Effects of cyclooxygenase products of arachidonic acid metabolism on cutaneous nociceptive threshold in the rat.

abstract：:Flexion movements induced by cortical stimulation and the associated postural adjustments in bilaterally pyramidotomised cats have been studied by means of an apparatus which measures separately the changes of force under each limb in the upright position of the animal. The results show: (1) The general motor behaviou...

journal_title：Brain research

authors： Nieoullon A,Gahéry Y

更新日期：1978-06-23 00:00:00

abstract：:Opiate regulation of the nuclear proto-oncogene c-fos was studied in the locus coeruleus (LC) and other regions of rat brain by immunoblotting, northern blotting, and in situ hybridization procedures. Precipitation of opiate withdrawal in rats, which is known to increase LC firing rates 4-fold, led to a two- to three-...

journal_title：Brain research

authors： Hayward MD,Duman RS,Nestler EJ

更新日期：1990-08-20 00:00:00

abstract：:In the present study we analyzed the effect of ascorbate (0.8 mM)/Fe2+ (2.5 microM)-induced membrane lipid peroxidation on the levels of intracellular free calcium,[Ca2+]i and on the possible mechanisms involved in the perturbation of intracellular calcium homeostasis during oxidative stress. For this purpose, the inf...

journal_title：Brain research

authors： Pereira C,Ferreira C,Carvalho C,Oliveira C

更新日期：1996-03-25 00:00:00

abstract：:Basal sleep amounts in adrenalectomized rats (AdX), as compared to intact animals, exhibit a significant increase in slow-wave sleep (SWS), a tendency towards an increase in paradoxical sleep (PS), and circadian rhythms (SWS and PS) flattened in amplitude. An immobilization stress (IS) of 1 h, imposed on AdX rats at t...

journal_title：Brain research

authors： Bonnet C,Marinesco S,Debilly G,Kovalzon V,Cespuglio R

更新日期：2000-01-24 00:00:00

abstract：:The aim of this study was to test the role of the perifornical hypothalamus and adjacent areas in the behavioral and cardiovascular responses to two forms of stress, conditioned fear to context and restraint. Of particular interest was the role of the hypocretin (orexin) containing neurons in these responses. Rats imp...

journal_title：Brain research

authors： Furlong T,Carrive P

更新日期：2007-01-12 00:00:00

abstract：:During embryogenesis, transient expression of nestin in proliferating neuroepithelial stem cells signals the commitment of progenitor cells to differentiate. Although adult mammalian brain contains very little nestin, significant upregulation of nestin has been reported following cerebral injury, leading to speculatio...

journal_title：Brain research

authors： Douen AG,Dong L,Vanance S,Munger R,Hogan MJ,Thompson CS,Hakim AM

更新日期：2004-05-22 00:00:00

abstract：:Glia represents the most numerous group of nervous system cells and CNS development and function depend on glial cells. We developed a purified Muller glia culture to investigate the expression of several neurotransmitter markers on these cells, such as dopaminergic, cholinergic, GABAergic and peptidergic receptors or...

journal_title：Brain research

authors： Kubrusly RC,da Cunha MC,Reis RA,Soares H,Ventura AL,Kurtenbach E,de Mello MC,de Mello FG

更新日期：2005-03-21 00:00:00

abstract：:Female golden-mantled ground squirrels that sustained complete ablation of the suprachiasmatic nucleus (SCNx) were housed pre- and post-operatively at 23 degrees C and then at 6.5 degrees C for 5-7 yr. SCNx and control animals held at the higher temperature manifested circannual rhythms (CARs) in body mass. In contras...

journal_title：Brain research

authors： Ruby NF,Dark J,Heller HC,Zucker I

更新日期：1998-01-26 00:00:00

abstract：:Recordings of single unit activity before, during and after a 1-h continuous exposure were made from the mitral cell layer of the olfactory bulbs of awake rabbits. Thirteen complete 1-h exposures were performed using 8 neurons, while a further 6 neurons were lost before the end of the exposure. During the first few mi...

journal_title：Brain research

authors： Chaput MA,Panhuber H

更新日期：1982-10-28 00:00:00

abstract：:We have used the post-embedding immunogold labelling method using antibodies to gamma-aminobutyric acid (GABA) to obtain quantitative data on the distribution, frequency, postsynaptic targets and ultrastructural characteristics of GABA-immunoreactive (GABA-IR) boutons in the trigeminal motor nucleus of rats. We have a...

journal_title：Brain research

authors： Saha S,Appenteng K,Batten TF

更新日期：1991-10-04 00:00:00

abstract：:The quantitative autoradiographic method with L-(35S)methionine was used to determine the effects of 1-acute (4h) and 2-chronic (14 days) immobilization stress followed by one week of recovery. Acute stress induced a significant decrease in methionine incorporation into proteins in 17 of the 35 brain structures examin...

journal_title：Brain research

authors： Giaume M,Grange E,Baubet V,Gay N,Sermet E,Sarda N,Bobillier P

更新日期：1995-03-27 00:00:00

abstract：:Hydrocephalus with aqueduct stenosis was a consistent feature in mice which received a single intraperitoneal injection of 6-aminonicotinamide (6-AN) on day 5 postnatal. Chronological investigation revealed that 6-AN-treated mice had aqueductal obstruction with edematously swollen ependymal cells and spongy changes in...

journal_title：Brain research

authors： Aikawa H,Suzuki K

更新日期：1985-10-01 00:00:00

abstract：:Two rat lines bred for kindling susceptibility were previously observed to engage in different behavioral strategies in tests of emotionality. In order to extend past research on defensive behaviors in these strains which largely used males, Fast- and Slow-kindling females were assessed for anxiety-like behaviors in a...

journal_title：Brain research

authors： Runke D,McIntyre DC

更新日期：2008-11-13 00:00:00

abstract：:Microinjections of monosodium glutamate (MSG; 300 microgram/0.5 microliter) into the hippocampus of the adult rat result in only marginal damage to local neurons. Perforant path transections, removing glutamatergic afferents to hippocampal granule cells, make the latter markedly more vulnerable to a subsequent MSG inj...

journal_title：Brain research

authors： Köhler C,Schwarcz R

更新日期：1981-05-04 00:00:00

abstract：:The 2,3-benzodiazepine derivative GYKI 52466 has been well characterized as a negative modulator of AMPA-type glutamate receptors. The present study re-examined the effects of GYKI 52466 on AMPA receptor-mediated currents in patches excised from pyramidal neurons in the hippocampal CA1 field and found that this drug h...

journal_title：Brain research

authors： Arai AC

更新日期：2001-02-23 00:00:00

abstract：:Lifelong bilingualism is associated with the delayed diagnosis of dementia, suggesting bilingual experience is relevant to brain health in aging. While the effects of bilingualism on cognitive functions across the lifespan are well documented, less is known about the neural substrates underlying differential behaviour...

journal_title：Brain research

authors： Olsen RK,Pangelinan MM,Bogulski C,Chakravarty MM,Luk G,Grady CL,Bialystok E

更新日期：2015-07-01 00:00:00

abstract：:Protein kinase C (PKC) activity was measured in rat brain with 2 h of middle cerebral artery (MCA) and common carotid artery (CCA) occlusion, using dual autoradiography of [14C]iodoantipyrine (IAP) and [3H]phorbol-12,13-dibutyrate (PDBu). In the ischemic brain, it required more than 120 min of incubation to obtain a p...

journal_title：Brain research

authors： Tohyama Y,Sako K,Yonemasu Y

更新日期：1997-03-07 00:00:00

abstract：:The density of specific prostaglandin E2 (PGE2) binding sites was quantitatively mapped in the rat brain using in vitro autoradiography. The anterior wall of the third ventricle and the nucleus solitary tract were found to have a very high density of binding sites (greater than 15 fmol/mg tissue). Two thalamic nuclei ...

journal_title：Brain research

authors： Matsumura K,Watanabe Y,Imai-Matsumura K,Connolly M,Koyama Y,Onoe H,Watanabe Y

更新日期：1992-05-29 00:00:00

abstract：:It has been accepted that the descending system from the nucleus locus coeruleus (LC)/nucleus subcoeruleus (SC) plays a significant role in spinal nociceptive processing. The present study was designed to examine modulation of nociceptive processing in the caudal part of the trigeminal sensory nuclear complex, the tri...

journal_title：Brain research

authors： Tsuruoka M,Matsutani K,Maeda M,Inoue T

更新日期：2003-12-12 00:00:00

abstract：:Opiates and cannabinoids are among the most widely consumed habit-forming drugs in humans. Several studies have demonstrated the existence of interactions between both kind of drugs in a variety of effects and experimental models. The present study has been focused to determine whether perinatal delta9-tetrahydrocanna...

journal_title：Brain research

authors： Vela G,Martín S,García-Gil L,Crespo JA,Ruiz-Gayo M,Fernández-Ruiz JJ,García-Lecumberri C,Pélaprat D,Fuentes JA,Ramos JA,Ambrosio E

更新日期：1998-10-05 00:00:00

abstract：:The involvement of striatal cholinergic neurons in the release of dopamine (DA) elicited by the mu-opioid receptor agonist DAGO ([D-Ala2, NMePhe4-Gly5(ol)]enkephalin) was explored. The striatal release of DA was measured by microdialysis in rats anesthetized with chloral hydrate. When infused in the striatum, through ...

journal_title：Brain research

authors： Dourmap N,Clero E,Costentin J

更新日期：1997-02-28 00:00:00

abstract：:The in vitro capacity of sympathetic superior cervical ganglia (SCG) to take up [3H]choline from the extracellular medium, to synthesize acetylcholine from [3H]choline, and to release [3H]acetylcholine in response to a high K+ concentration, were examined in rats throughout a 24-h cycle. Both the release of [3H]acetyl...

journal_title：Brain research

authors： González Burgos GR,Rosenstein RE,Cardinali DP

更新日期：1994-02-14 00:00:00

abstract：:Artificial CSF containing 12mEq/1 of potassium (4 times normal concentration) was perfused over the surface of normal neocortex in 10 locally or barbiturate anesthetized cats. Extracellular potassium concentrations ([K+]OS) were measured as a function of time to 8 h and of depth to 3 mm. Analysis of the [K+]O versus d...

journal_title：Brain research

authors： Fisher RS,Pedley TA,Prince DA

更新日期：1976-01-16 00:00:00

abstract：:Bilateral intraventricular injections of 6-hydroxydopamine depleted dopamine (DA) in striatal tissue of rats by 88%. Tail shock increased DA in striatal extracellular fluid of these rats from 10 to 17 pg/20 microliters as measured by microdialysis, values less than half those seen in normal striatum. The increase was ...

journal_title：Brain research

authors： Keefe KA,Stricker EM,Zigmond MJ,Abercrombie ED

更新日期：1990-09-17 00:00:00

abstract：:Recordings were made from single neurons in the rat's central nucleus of the inferior colliculus (ICc). Binaural responses were studied when dichotic tone bursts with various interaural-level differences were presented simultaneously or with a contralateral delay. These dichotic tone bursts allowed us to probe tempora...

journal_title：Brain research

authors： Zhang H,Kelly JB

更新日期：2009-12-15 00:00:00

abstract：:The outer plexiform layer (OPL) of the retina has been studied in the developing cat, from E (embryonic day) 30. Prior to E51 the layer could not be detected, the retina comprising two cell layers, an inner layer which becomes the ganglion cell layer of the adult, and an outer 'neuroblast' layer. The OPL was first det...

journal_title：Brain research

authors： Rapaport DH,Stone J

更新日期：1982-11-01 00:00:00

abstract：:This study aimed to identify the neural correlates of aggression-related attentional selectivity to angry faces in physical aggression. Physical aggression in a non-clinical sample of young men (N = 36) was measured using an aggression questionnaire. Visual attentional bias to angry faces was assessed using a dot-prob...

journal_title：Brain research

authors： Crago RV,Renoult L,Biggart L,Nobes G,Satmarean T,Bowler JO

更新日期：2019-11-15 00:00:00

abstract：:Cerebral cortex membranes from rats habituated to manipulations preceding decapitation (habituated rats) had 40% higher GABA binding than membranes from naive animals. Diazepam (5 X 10(-6) M), added to membranes from naive rats, increased GABA binding to the level of habituated rats, but failed to induce any further i...

journal_title：Brain research

authors： Biggio G,Concas A,Serra M,Salis M,Corda MG,Nurchi V,Crisponi C,Gessa GL

更新日期：1984-07-02 00:00:00

abstract：:In anesthetized cats, medial gastrocnemius motor units (MUs) were electrically stimulated via their ventral-root axons with independent random patterns. Muscle tension and homonymous alpha-motoneuron (alpha-MN) membrane potential fluctuations in response to these stimuli were recorded simultaneously. Cross-correlating...

journal_title：Brain research

authors： Koehler W,Hamm TM,Enoka RM,Stuart DG,Windhorst U

更新日期：1985-09-23 00:00:00

abstract：:At a physiologically relevant concentration (1.25 microM), aluminum had an activating effect on oligodendrocyte cell cultures, similar to that previously reported for other cell types. G protein-linked signal transduction was stimulated as indicated by enhanced production of IP3, and protein synthesis was increased. A...

journal_title：Brain research

authors： Golub MS,Zhang W,Keen CL,Goldkorn T

更新日期：2002-06-21 00:00:00