Identification of a receptor-binding pocket on the envelope protein of friend murine leukemia virus.

abstract：:Myeloblastosis-associated virus type 1 (MAV1) derived from a molecular clone of infectious proviral DNA (B. Perbal, J. S. Lipsick, J. Svoboda, R. F. Silva, and M. A. Baluda, J. Virol. 56:240-244, 1985) was shown to specifically induce nephroblastoma in chickens and therefore belongs to the MAV-N class. We show that ne...

journal_title：Journal of virology

authors： Soret J,Dambrine G,Perbal B

更新日期：1989-04-01 00:00:00

abstract：:Most highly pathogenic avian influenza A viruses cause only mild clinical signs in ducks, serving as an important natural reservoir of influenza A viruses. However, we isolated two H5N1 viruses that are genetically similar but differ greatly in virulence in ducks. A/Chicken/Jiangsu/k0402/2010 (CK10) is highly pathogen...

journal_title：Journal of virology

authors： Hu J,Hu Z,Mo Y,Wu Q,Cui Z,Duan Z,Huang J,Chen H,Chen Y,Gu M,Wang X,Hu S,Liu H,Liu W,Liu X,Liu X

更新日期：2013-10-01 00:00:00

abstract：:Viruses encode proteins that disrupt chemokine responses. The murine gammaherpesvirus 68 gene M3 encodes a chemokine binding protein (vCKBP-3) which has no sequence similarity to chemokine receptors but inhibits chemokine receptor binding and activity. We have used a panel of CXCL8 analogs to identify the structural r...

journal_title：Journal of virology

authors： Webb LM,Clark-Lewis I,Alcami A

更新日期：2003-08-01 00:00:00

abstract：:Circulating interferon production, induced by Newcastle disease virus, is about seven times higher in C(57) Black mice than i Balb/c/Gif mice. A Mendelian analysis was carried out and circulating interferon production was measured in reciprocal F(1) hybrids, in the F(2) generation, in progeny of backcrosses of F(1) hy...

journal_title：Journal of virology

authors： de Maeyer E,de Maeyer-Guignard J

更新日期：1969-05-01 00:00:00

abstract：UNLABELLED:PB1-F2 protein, the 11th influenza A virus (IAV) protein, is considered to play an important role in primary influenza virus infection and postinfluenza secondary bacterial pneumonia in mice. The functional role of PB1-F2 has been reported to be a strain-specific and host-specific phenomenon. Its precise con...

journal_title：Journal of virology

authors： Deventhiran J,Kumar SR,Raghunath S,Leroith T,Elankumaran S

更新日期：2015-10-14 00:00:00

abstract：:N(pro) is a multifunctional autoprotease unique to pestiviruses. The interacting partners of the N(pro) protein of classical swine fever virus (CSFV), a swine pestivirus, have been insufficiently defined. Using a yeast two-hybrid screen, we identified poly(C)-binding protein 1 (PCBP1) as a novel interacting partner of...

journal_title：Journal of virology

authors： Li D,Li S,Sun Y,Dong H,Li Y,Zhao B,Guo D,Weng C,Qiu HJ

更新日期：2013-02-01 00:00:00

abstract：:The 3'-end host-virus junction fragments from two bovine leukemia virus (BLV)-induced lymphoid tumors (tumors 15-4 and 1351), each containing a single provirus, were used as probes to detect large restriction fragments flanking these proviruses. The DNAs from 28 other independent BLV-induced tumors were checked by Sou...

journal_title：Journal of virology

authors： Kettmann R,Deschamps J,Couez D,Claustriaux JJ,Palm R,Burny A

更新日期：1983-07-01 00:00:00

abstract：:A panel of 16 monoclonal antibodies recognizing M protein (M1) of influenza virus was generated. Competition analyses resulted in localization of 14 monoclonal antibodies to three antigenic sites. Three monoclonal antibodies localized to site 1B recognized a peptide synthesized to M1 (residues 220 to 236) with enzyme-...

journal_title：Journal of virology

authors： Bucher D,Popple S,Baer M,Mikhail A,Gong YF,Whitaker C,Paoletti E,Judd A

更新日期：1989-09-01 00:00:00

abstract：:A number of eucaryotic viruses have devised strategies to minimize the deleterious effects on protein synthesis caused by activation of the interferon-induced, double-stranded-RNA-activated protein kinase, P68. In a recent report, we described the down regulation of the P68 protein kinase in cells infected by human im...

journal_title：Journal of virology

authors： Roy S,Agy M,Hovanessian AG,Sonenberg N,Katze MG

更新日期：1991-02-01 00:00:00

abstract：:Extracts made from human respiratory syncytial virus (RSV)-infected Hep-2 cells synthesized mRNAs encoded by all known viral genes. In contrast, RSV ribonucleoproteins purified from infected cells failed to transcribe in vitro; transcription was restored by addition of a cytoplasmic extract of uninfected Hep-2 cells, ...

journal_title：Journal of virology

authors： Barik S

更新日期：1992-11-01 00:00:00

abstract：:Rfv3 is an autosomal dominant gene that influences the recovery of resistant mice from Friend retrovirus (FV) infection by limiting viremia and promoting a more potent neutralizing antibody response. We previously reported that Rfv3 is encoded by Apobec3, an innate retrovirus restriction factor. However, it was recent...

journal_title：Journal of virology

authors： Santiago ML,Smith DS,Barrett BS,Montano M,Benitez RL,Pelanda R,Hasenkrug KJ,Greene WC

更新日期：2011-01-01 00:00:00

abstract：:Poliovirus-infected cells undergo an increase in cytoplasmic calcium concentrations from the 4th h postinfection. The protein responsible for this effect was identified by the expression of different poliovirus nonstructural proteins in HeLa cells by using a recombinant vaccinia virus system. Synthesis of protein 2BC ...

journal_title：Journal of virology

authors： Aldabe R,Irurzun A,Carrasco L

更新日期：1997-08-01 00:00:00

abstract：:In most human immunodeficiency virus type 1 (HIV-1)-infected individuals who achieve viral loads of <50 copies/ml during highly active antiretroviral therapy (HAART), low levels of plasma virus remain detectable for years by ultrasensitive methods. The relative contributions of ongoing virus replication and virus prod...

journal_title：Journal of virology

authors： Shiu C,Cunningham CK,Greenough T,Muresan P,Sanchez-Merino V,Carey V,Jackson JB,Ziemniak C,Fox L,Belzer M,Ray SC,Luzuriaga K,Persaud D,Pediatric AIDS Clinical Trials Group P1059 Team.

更新日期：2009-10-01 00:00:00

abstract：:The membrane glycoproteins G1 and G2 of Uukuniemi virus, a member of the Bunyaviridae family, are cotranslationally cleaved from a common precursor in the endoplasmic reticulum (ER). Here, we show that newly made G1 and G2 associate transiently with calnexin and calreticulin, two lectins involved in glycoprotein foldi...

journal_title：Journal of virology

authors： Veijola J,Pettersson RF

更新日期：1999-07-01 00:00:00

abstract：:RNA recombination occurs frequently during replication of tombusviruses and carmoviruses, which are related small plus-sense RNA viruses of plants. The most common recombinants generated by these viruses are either defective interfering (DI) RNAs or chimeric satellite RNAs, which are thought to be generated by templat...

journal_title：Journal of virology

authors： Cheng CP,Nagy PD

更新日期：2003-11-01 00:00:00

abstract：:We determined the capacity of microcapsules formed by the combination of sodium alginate, an aqueous anionic polymer, and spermine hydrochloride, an aqueous cationic amine, to enhance protection against rotavirus challenge in mice. Adult BALB/c mice were orally inoculated with either free or microencapsulated rotaviru...

journal_title：Journal of virology

authors： Moser CA,Speaker TJ,Offit PA

更新日期：1998-05-01 00:00:00

abstract：:Mouse mammary tumor virus (MMTV)-induced mammary adenocarcinomas can develop from several different premalignant precursors common in GR mice. Insertion mutagenesis of the mammary protooncogenes int-1 and int-2 was studied in this multistep system by analyzing samples from various stages of neoplastic development for ...

journal_title：Journal of virology

authors： Morris DW,Barry PA,Bradshaw HD Jr,Cardiff RD

更新日期：1990-04-01 00:00:00

abstract：:Proteins located in the tegument layer of herpesvirus particles play important roles in the replicative cycle at both early and late times after infection. As major constituents of the virion, they execute important functions in particular during formation of progeny virions. These functions have mostly been elucidate...

journal_title：Journal of virology

authors： Michael K,Klupp BG,Mettenleiter TC,Karger A

更新日期：2006-02-01 00:00:00

abstract：:The mechanisms involved in the emergence of virulent mammalian viruses were investigated in the adult immunodeficient SCID mouse infected by the attenuated prototype strain of the parvovirus Minute Virus of Mice (MVMp). Cloned MVMp intravenously inoculated in mice consistently evolved during weeks of subclinical infec...

journal_title：Journal of virology

authors： Rubio MP,López-Bueno A,Almendral JM

更新日期：2005-09-01 00:00:00

abstract：:The novel low-pathogenic avian influenza A H7N9 viruses (LPAI H7N9 viruses) have been a threat to public health since their emergence in 2013 because of the high rates of mortality and morbidity that they cause. Recently, highly pathogenic variants of these avian influenza A H7N9 viruses (HPAI H7N9 viruses) have emerg...

journal_title：Journal of virology

authors： Yang L,Zhu W,Li X,Chen M,Wu J,Yu P,Qi S,Huang Y,Shi W,Dong J,Zhao X,Huang W,Li Z,Zeng X,Bo H,Chen T,Chen W,Liu J,Zhang Y,Liang Z,Shi W,Shu Y,Wang D

更新日期：2017-11-14 00:00:00

abstract：:The unfolded-protein response (UPR), activated by sensor molecules PERK, ATF6, and IRE1 to resolve endoplasmic reticulum (ER) stress, has emerged as a key target for host cells and viruses to control the infection outcomes. The UPR regulates ER protein folding, controls cell fate upon ER stress, and plays an important...

journal_title：Journal of virology

authors： Qian Z,Xuan B,Chapa TJ,Gualberto N,Yu D

更新日期：2012-06-01 00:00:00

abstract：:The long terminal repeat U3 sequences were determined for multiple feline leukemia virus proviruses isolated from naturally occurring T-cell tumors. Heterogeneity was evident, even among proviruses cloned from individual tumors. Proviruses with one, two, or three repeats of the long terminal repeat enhancer sequences ...

journal_title：Journal of virology

authors： Fulton R,Plumb M,Shield L,Neil JC

更新日期：1990-04-01 00:00:00

abstract：:For viruses with segmented genomes, genetic diversity is generated by genetic drift, reassortment, and recombination. Recombination produces RNA populations distinct from full-length gene segments and can influence viral population dynamics, persistence, and host immune responses. Viruses in the Reoviridae family, inc...

journal_title：Journal of virology

authors： Smith SC,Gribble J,Diller JR,Wiebe MA,Thoner TW Jr,Denison MR,Ogden KM

更新日期：2021-01-20 00:00:00

abstract：:Induction of virus-specific T-cell responses in mucosal as well as systemic compartments of the immune system is likely to be a critical feature of an effective AIDS vaccine. We investigated whether virus-specific CD8(+) lymphocytes induced in rhesus macaques by immunization with attenuated simian immunodeficiency vir...

journal_title：Journal of virology

authors： Cromwell MA,Veazey RS,Altman JD,Mansfield KG,Glickman R,Allen TM,Watkins DI,Lackner AA,Johnson RP

更新日期：2000-09-01 00:00:00

abstract：:Cottontail rabbit papillomavirus induces strictly epithelial tumors in both cottontail and domestic rabbits. A high proportion of the initial benign papillomas progress within 8 to 14 months to invasive carcinomas. With the help of mRNA-specific riboprobes for E6, E7, E1, E2, L1 and L2, we investigated by in situ hybr...

journal_title：Journal of virology

authors： Zeltner R,Borenstein LA,Wettstein FO,Iftner T

更新日期：1994-06-01 00:00:00

abstract：:DNA replication intermediates of three plasmids containing all or part of a modified Epstein-Barr virus cis-acting plasmid maintenance region (oriP) were examined to further investigate oriP function. Replication intermediates were analyzed in vivo and in vitro by neutral-neutral two-dimensional gel electrophoresis. T...

journal_title：Journal of virology

authors： Platt TH,Tcherepanova IY,Schildkraut CL

更新日期：1993-03-01 00:00:00

abstract：:Therapeutic strategies for the treatment of acute retroviral infections have relied mainly on antiviral drugs. In this study we used the Friend virus model system to demonstrate that enhancement of the immune system can also have dramatic therapeutic effects. Since resistance to Friend virus-induced leukemia in mice i...

journal_title：Journal of virology

authors： Olbrich AR,Schimmer S,Heeg K,Schepers K,Schumacher TN,Dittmer U

更新日期：2002-11-01 00:00:00

abstract：:Widespread distribution of highly pathogenic avian H5N1 influenza viruses in domesticated and wild birds continues to pose a threat to public health, as interspecies transmission of virus has resulted in increasing numbers of human disease cases. Although the pathogenic mechanism(s) of H5N1 influenza viruses has not b...

journal_title：Journal of virology

authors： Szretter KJ,Gangappa S,Belser JA,Zeng H,Chen H,Matsuoka Y,Sambhara S,Swayne DE,Tumpey TM,Katz JM

更新日期：2009-06-01 00:00:00

abstract：:Replication of poliovirus (PV) is restricted to a few sites, including the brain and spinal cord. However, this neurotropism is not conserved in cultured cells. Monkey kidney cells become susceptible to PV infection after cultivation in vitro, and cell lines of monolayer cultures from almost any tissue of primates are...

journal_title：Journal of virology

authors： Yoshikawa T,Iwasaki T,Ida-Hosonuma M,Yoneyama M,Fujita T,Horie H,Miyazawa M,Abe S,Simizu B,Koike S

更新日期：2006-05-01 00:00:00

abstract：:A series of recombinant molecules were constructed which direct the expression of the easily assayed gene chloramphenicol acetyltransferase. We have used these recombinants to show that the 73/72-base-pair tandem repeat unit from the Moloney murine sarcoma virus long terminal repeat shares a number of properties with ...

journal_title：Journal of virology

authors： Laimins LA,Gruss P,Pozzatti R,Khoury G

更新日期：1984-01-01 00:00:00