Gene with quantitative effect on circulating interferon induced by Newcastle disease virus.

abstract：:Human La protein has been implicated in facilitating internal ribosome entry site (IRES)-mediated translation of hepatitis C virus (HCV). Earlier, we demonstrated that the RNA recognition motif (RRM) encompassing residues 112 to 184 of La protein [La (112-184)] interacts with the HCV IRES near the initiator AUG codon....

journal_title：Journal of virology

authors： Mondal T,Ray U,Manna AK,Gupta R,Roy S,Das S

更新日期：2008-12-01 00:00:00

abstract：:Bovine herpesvirus 1 (BHV-1) specifies and unspliced early 2.6-kb RNA (ER2.6) which is 3' coterminal with exon 2 of the 2.9-kb immediate-early (IE) RNA. The two transcripts have a common open reading frame (676 codons). The predicted protein, designated BHV-1 infected cell protein 0 (BICP0), contains a zinc finger dom...

journal_title：Journal of virology

authors： Fraefel C,Zeng J,Choffat Y,Engels M,Schwyzer M,Ackermann M

更新日期：1994-05-01 00:00:00

abstract：:Replication of the genomic RNA of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by replicase polyproteins that are processed by two viral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro). Previously, we showed that SARS-CoV PLpro processes the replicase polyprotein at three ...

journal_title：Journal of virology

authors： Barretto N,Jukneliene D,Ratia K,Chen Z,Mesecar AD,Baker SC

更新日期：2005-12-01 00:00:00

abstract：:The D4R gene of vaccinia virus encodes a functional uracil-DNA glycosylase that is essential for viral viability (D. T. Stuart, C. Upton, M. A. Higman, E. G. Niles, and G. McFadden, J. Virol. 67:2503-2513, 1993), and a D4R mutant, ts4149, confers a conditional lethal defect in viral DNA replication (A. K. Millns, M. S...

journal_title：Journal of virology

authors： Ellison KS,Peng W,McFadden G

更新日期：1996-11-01 00:00:00

abstract：:A fibrosarcoma was induced in a hamster by bovine papilloma virus type 2 (BPV2). The content of BPV2 DNA sequences was measured by DNA-DNA and cRNA-DNA hybridizations. The tumor contained approximately 300 BPV2 genome equivalents per cell. Southern blot hybridization indicated that the viral DNA was in free form, the ...

journal_title：Journal of virology

authors： Moar MH,Campo MS,Laird HM,Jarrett WF

更新日期：1981-09-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1)-infected macrophages damage mature neurons in the brain, although their effect on neuronal development has not been clarified. In this study, we show that HIV-1-infected macrophages produce factors that impair the development of neuronal precursor cells and that soluble vira...

journal_title：Journal of virology

authors： Kitayama H,Miura Y,Ando Y,Hoshino S,Ishizaka Y,Koyanagi Y

更新日期：2008-03-01 00:00:00

abstract：:Herpesvirus proteins pUL34 and pUL31 form a complex at the inner nuclear membrane (INM) which is necessary for efficient nuclear egress. Pseudorabies virus (PrV) pUL34 is a type II membrane protein of 262 amino acids (aa). The transmembrane region (TM) is predicted to be located between aa 245 and 261, leaving only on...

journal_title：Journal of virology

authors： Schuster F,Klupp BG,Granzow H,Mettenleiter TC

更新日期：2012-02-01 00:00:00

abstract：:We have analyzed three cases of hepatitis C virus (HCV)-infected recipients who received blood from HCV-infected donors. Two recipients were exposed to two different HCV RNA-positive donors, and one was exposed to a single donor. All parental genomes from the actual infecting units of blood and the recipients were def...

journal_title：Journal of virology

authors： Laskus T,Wang LF,Radkowski M,Vargas H,Nowicki M,Wilkinson J,Rakela J

更新日期：2001-03-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is typically acquired asymptomatically in childhood. In contrast, infection later in life often leads to infectious mononucleosis (IM), a febrile illness characterized by anti-EBV IgM antibody positivity, high loads of circulating latently infected B cells, and a marked lymphocytosis caused by...

journal_title：Journal of virology

authors： Abbott RJ,Pachnio A,Pedroza-Pacheco I,Leese AM,Begum J,Long HM,Croom-Carter D,Stacey A,Moss PAH,Hislop AD,Borrow P,Rickinson AB,Bell AI

更新日期：2017-10-13 00:00:00

abstract：UNLABELLED:Despite the nutritional and health benefits of breast milk, breast milk can serve as a vector for mother-to-child HIV transmission. Most HIV-infected infants acquire HIV through breastfeeding. Paradoxically, most infants breastfed by HIV-positive women do not become infected. This is potentially attributed t...

journal_title：Journal of virology

authors： Wahl A,Baker C,Spagnuolo RA,Stamper LW,Fouda GG,Permar SR,Hinde K,Kuhn L,Bode L,Aldrovandi GM,Garcia JV

更新日期：2015-11-01 00:00:00

abstract：:A distinctive feature of chronic human immunodeficiency virus type 1 (HIV-1) infection is the presence of multiple coexisting genetic variants, or subpopulations, that comprise the HIV-1 population detected in the peripheral blood. Analysis of HIV-1 RNA decay dynamics during the initiation of highly active antiretrovi...

journal_title：Journal of virology

authors： Ince WL,Harrington PR,Schnell GL,Patel-Chhabra M,Burch CL,Menezes P,Price RW,Eron JJ Jr,Swanstrom RI

更新日期：2009-05-01 00:00:00

abstract：:Influenza A virus matrix protein M1 is involved in multiple stages of the viral infectious cycle. Despite its functional importance, our present understanding of this essential viral protein is limited. The roles of a small subset of specific amino acids have been reported, but a more comprehensive understanding of th...

journal_title：Journal of virology

authors： Hom N,Gentles L,Bloom JD,Lee KK

更新日期：2019-06-14 00:00:00

abstract：:The expression of a human immunodeficiency virus (HIV) type 1 provirus (F12-HIV) cloned from a nonproducer, chronically infected CD4 down-regulated Hut-78 cell clone (F12) does not lead to the formation of viral particles and, upon transfection in HeLa CD4+ cells, confers resistance to HIV superinfection without affec...

journal_title：Journal of virology

authors： Federico M,Nappi F,Ferrari G,Chelucci C,Mavilio F,Verani P

更新日期：1995-11-01 00:00:00

abstract：:Varicella-zoster virus (VZV) is a herpesvirus and is the causative agent of chicken pox (varicella) and shingles (herpes zoster). Active immunization against varicella became possible with the development of live attenuated varicella vaccine. The Oka vaccine strain was isolated in Japan from a child who had typical va...

journal_title：Journal of virology

authors： Tillieux SL,Halsey WS,Thomas ES,Voycik JJ,Sathe GM,Vassilev V

更新日期：2008-11-01 00:00:00

abstract：:The intracellular assembly of the transmissible gastroenteritis coronavirus (TGEV) was studied in infected swine testis (ST) cells at different postinfection times by using ultrathin sections of conventionally embedded infected cells, freeze-substitution, and methods for detecting viral proteins and RNA at the electro...

journal_title：Journal of virology

authors： Risco C,Muntión M,Enjuanes L,Carrascosa JL

更新日期：1998-05-01 00:00:00

abstract：:Rotavirus is the major cause of diarrhea among young infants in both humans and animals. Immune protection of newborns by vaccination is difficult to achieve since there is not enough time to mount an immune response before exposure to the virus. We have designed a vaccination strategy mediating transfer of neutralizi...

journal_title：Journal of virology

authors： Coste A,Sirard JC,Johansen K,Cohen J,Kraehenbuhl JP

更新日期：2000-10-01 00:00:00

abstract：:The adaptive immune system generates CD8 cytotoxic T lymphocytes (CTLs) as a major component of the protective response against viruses. Knowledge regarding the nature of the peptide sequences presented by HLA class I molecules and recognized by CTLs is thus important for understanding host-pathogen interactions. In t...

journal_title：Journal of virology

authors： Varela-Calvino R,Skowera A,Arif S,Peakman M

更新日期：2004-12-01 00:00:00

abstract：:Broad, multispecific CD4(+) and CD8(+) T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated in chronic HCV patients with a favorable response to antiviral treatment. In order to recapitulate all of ...

journal_title：Journal of virology

authors： Lin Y,Kwon T,Polo J,Zhu YF,Coates S,Crawford K,Dong C,Wininger M,Hall J,Selby M,Coit D,Medina-Selby A,McCoin C,Ng P,Drane D,Chien D,Han J,Vajdy M,Houghton M

更新日期：2008-08-01 00:00:00

abstract：:Harvard Medical School convened a meeting of biomedical and clinical experts on 5 March 2015 on the topic of "Rethinking the Response to Emerging Microbes: Vaccines and Therapeutics in the Ebola Era," with the goals of discussing the lessons from the recent Ebola outbreak and using those lessons as a case study to aid...

journal_title：Journal of virology

authors： Knipe DM,Whelan SP

更新日期：2015-08-01 00:00:00

abstract：:We have used immunofluorescence in parallel with transmission and scanning electron microscopy to characterize the unusual cytoplasmic and nucleolar accumulation of Simian virus 40 (SV40) virion protein (C antigen) at restrictive temperatures (39 to 41 C) in monkey cells infected with a temperature-sensitive mutant of...

journal_title：Journal of virology

authors： Widmer C,Robb JA

更新日期：1974-12-01 00:00:00

abstract：:Amphiphilic fatty acid derivatives having a 14- to 20-carbon cis-unsaturated alkyl chain were found to be potent inhibitors of the entry process of the lipid-containing bacteriophage PR4. ...

journal_title：Journal of virology

authors： Sands JA,Reinhardt A,Auperin D,Landin P

更新日期：1979-01-01 00:00:00

abstract：:The pandemic threat posed by emerging zoonotic influenza A viruses necessitates development of antiviral agents effective against various antigenic subtypes. Human monoclonal antibody (hMAb) targeting the hemagglutinin (HA) stalk offers a promising approach to control influenza virus infections. Here, we investigated ...

journal_title：Journal of virology

authors： Marjuki H,Mishin VP,Chai N,Tan MW,Newton EM,Tegeris J,Erlandson K,Willis M,Jones J,Davis T,Stevens J,Gubareva LV

更新日期：2016-11-14 00:00:00

abstract：:The lytic switch transactivator Zta initiates the ordered cascade of Epstein-Barr virus gene expression that culminates in virus production. Zta is a sequence-specific DNA-binding protein that transactivates early viral promotes via cis-acting sequences. Activation of some of these genes is mediated through binding to...

journal_title：Journal of virology

authors： Cayrol C,Flemington EK

更新日期：1995-07-01 00:00:00

abstract：:The beginning of the second century of research in the field of virology (the first virus was discovered in 1898) was marked by its amalgamation with bioinformatics, resulting in the birth of a new domain--viroinformatics. The availability of more than 100 Web servers and databases embracing all or specific viruses (f...

journal_title：Journal of virology

authors： Sharma D,Priyadarshini P,Vrati S

更新日期：2015-02-01 00:00:00

abstract：:We have characterized an inhibitory RNA element in the human immunodeficiency virus type 1 (HIV-1) gag coding sequence that prevents gag expression. The inhibition exerted by this element could be overcome by the presence of the Rev-responsive element in cis and of Rev protein in trans. To understand the mechanism of ...

journal_title：Journal of virology

authors： Schwartz S,Campbell M,Nasioulas G,Harrison J,Felber BK,Pavlakis GN

更新日期：1992-12-01 00:00:00

abstract：:The structure and replication of a cold-adapted, temperature-sensitive (TS) mutant of an Asian (H2N2) influenza virus was compared with that of its wild-type (WT) parent. Viruses were grown in a chicken kidney cell system, and at the nonpermissive temperature of 40 C, production of infectious TS virus was about 100,00...

journal_title：Journal of virology

authors： Kendal AP,Kiley MP,Maassab HF

更新日期：1973-12-01 00:00:00

abstract：:A coxsackievirus B3 (CB3) isolate adapted to growth in RD cells shows an alteration in cell tropism as a result of its capacity to bind a 70-kDa cell surface molecule expressed on these cells. We now show that this molecule is the complement regulatory protein, decay-accelerating factor (DAF) (CD55). Anti-DAF antibodi...

journal_title：Journal of virology

authors： Bergelson JM,Mohanty JG,Crowell RL,St John NF,Lublin DM,Finberg RW

更新日期：1995-03-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) has a tropism for T lymphocytes and monocytes/macrophages, suggesting that HHV-6 infection affects the immunosurveillance system. In the present study, we investigated the HHV-6-induced phenotypic and functional alterations of dendritic cells (DCs), which are professional antigen-presenting...

journal_title：Journal of virology

authors： Kakimoto M,Hasegawa A,Fujita S,Yasukawa M

更新日期：2002-10-01 00:00:00

abstract：:When human A431 cells, which carry high numbers of epidermal growth factor (EGF) receptors, are exposed to EGF, the total content of phosphotyrosine in cell protein is increased, the EGF receptor becomes phosphorylated at tyrosine, and new phosphotyrosine-containing 36,000- and 81,000-dalton proteins are detected. We ...

journal_title：Journal of virology

authors： Cooper JA,Scolnick EM,Ozanne B,Hunter T

更新日期：1983-12-01 00:00:00

abstract：:An immediate-early protein of murine cytomegalovirus (MCMV), pp89, elicits an immunodominant and protective major histocompatibility complex (MHC) class I Ld-restricted CD8+ T-lymphocyte response. Remarkably, presentation of the naturally processed peptide of pp89, the nonapeptide YPHFMPTNL, is abolished during permis...

journal_title：Journal of virology

authors： Hengel H,Lucin P,Jonjić S,Ruppert T,Koszinowski UH

更新日期：1994-01-01 00:00:00