Chromosome integration domain for bovine leukemia provirus in tumors.

abstract：:Human herpesvirus 8 (HHV8) downregulates major histocompatibility complex (MHC) class I complexes from the plasma membrane via two of its genes, K3 and K5. The N termini of K3 and K5 contain a plant homeodomain (PHD) predicted to be structurally similar to RING domains found in E3 ubiquitin ligases. In view of the imp...

journal_title：Journal of virology

authors： Lorenzo ME,Jung JU,Ploegh HL

更新日期：2002-06-01 00:00:00

abstract：:The feline homolog of the alpha-chemokine receptor CXCR4 has recently been shown to support cell-cell fusion mediated by CXCR4-dependent strains of human immunodeficiency virus (HIV) and strains of feline immunodeficiency virus (FIV) that have been selected for growth in the Crandell feline kidney (CrFK) cell line. In...

journal_title：Journal of virology

authors： Willett BJ,Adema K,Heveker N,Brelot A,Picard L,Alizon M,Turner JD,Hoxie JA,Peiper S,Neil JC,Hosie MJ

更新日期：1998-08-01 00:00:00

abstract：:Phylogenetic analyses demonstrate significant diversity in worldwide circulating strains of human immunodeficiency virus type 1 (HIV-1). Detailed studies have revealed a complex pattern of intersubtype recombinations, as well as evidence of sub-subtypes circulating in various populations. In this study, we characteriz...

journal_title：Journal of virology

authors： Meloni ST,Kim B,Sankalé JL,Hamel DJ,Tovanabutra S,Mboup S,McCutchan FE,Kanki PJ

更新日期：2004-11-01 00:00:00

abstract：:HeLa cells infected with human rhinovirus type 2 synthesize a mixture of single-and double-stranded ribonucleic acid (RNA). The RNA synthesized by the membrane-bound RNA polymerase complex in vitro is also a mixture of single- and double-stranded RNA, whereas the deoxycholate-treated RNA polymerase complex synthesized...

journal_title：Journal of virology

authors： Yin FH,Knight E Jr

更新日期：1972-07-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) Vif recruits a cellular ubiquitin ligase complex to degrade antiviral APOBEC3 enzymes (APOBEC3C-H) and PP2A phosphatase regulators (PPP2R5A to PPP2R5E). While APOBEC3 antagonism is the canonical function of HIV-1 Vif, this viral accessory protein is also known to trigger G2/...

journal_title：Journal of virology

authors： Salamango DJ,McCann JL,Demir Ö,Becker JT,Wang J,Lingappa JR,Temiz NA,Brown WL,Amaro RE,Harris RS

更新日期：2020-10-14 00:00:00

abstract：:A/duck/Shanghai/28-1/2009(H4N2) (DK28) was isolated from a live poultry market in Shanghai, China. Using PCR and sequencing analysis, we obtained the complete genome sequences of the DK28 virus. The sequence analysis demonstrated that this H4N2 virus was a novel multiple-gene reassortant avian influenza virus (AIV) wh...

journal_title：Journal of virology

authors： Teng Q,Ji X,Li G,Li X,Li Z

更新日期：2012-11-01 00:00:00

abstract：:Current human immunodeficiency virus type 1 (HIV-1) envelope vaccine candidates elicit high antibody binding titers with neutralizing activity against T-cell line-adapted but not primary HIV-1 isolates. Serum antibodies from these human vaccine recipients were also found to be preferentially directed to linear epitope...

journal_title：Journal of virology

authors： VanCott TC,Mascola JR,Kaminski RW,Kalyanaraman V,Hallberg PL,Burnett PR,Ulrich JT,Rechtman DJ,Birx DL

更新日期：1997-06-01 00:00:00

abstract：:Natural evolution in primate lentiviral reverse transcriptase (RT) appears to have been constrained by the necessity to maintain function within an asymmetric protein composed of two identical primary amino acid sequences (66 kDa), of which one is cleaved (51 kDa). In this study, a detailed phylogenetic analysis now s...

journal_title：Journal of virology

authors： Tebit DM,Lobritz M,Lalonde M,Immonen T,Singh K,Sarafianos S,Herchenröder O,Kräusslich HG,Arts EJ

更新日期：2010-10-01 00:00:00

abstract：:RNA packaging signals (psi) from the 5' ends of murine and avian retroviral genomes have previously been shown to direct encapsidation of heterologous mRNA into the retroviral virion. The avian 5' packaging region has now been further characterized, and we have defined a 270-nucleotide sequence, A psi, which is suffic...

journal_title：Journal of virology

authors： Aronoff R,Hajjar AM,Linial ML

更新日期：1993-01-01 00:00:00

abstract：:The mechanism of action of hepatitis B virus (HBV) X protein in transcriptional transactivation and in tumorigenesis remains obscure. We have used the yeast two-hybrid system to identify a cellular protein that can interact with HBV X protein. This protein, designated X-associated protein 1 (XAP-1), is a human homolog...

journal_title：Journal of virology

authors： Lee TH,Elledge SJ,Butel JS

更新日期：1995-02-01 00:00:00

abstract：:Pancreatic islets from DBA/2 mice infected with the D variant of encephalomyocarditis (EMC-D) virus revealed lymphocytic infiltration with moderate to severe destruction of pancreatic beta cells. Our previous studies showed that the major population of infiltrating cells at the early stages of infection is macrophages...

journal_title：Journal of virology

authors： Hirasawa K,Jun HS,Maeda K,Kawaguchi Y,Itagaki S,Mikami T,Baek HS,Doi K,Yoon JW

更新日期：1997-05-01 00:00:00

abstract：:The adenovirus type 5 mutant dl1520 was engineered previously to be completely defective for E1B-55K functions. Recently, this mutant (also known as ONYX-015) has been suggested to replicate preferentially in p53(-) and some p53(+) tumor cell lines but to be attenuated in primary cultured cells (C. Heise, A. Sampson-J...

journal_title：Journal of virology

authors： Harada JN,Berk AJ

更新日期：1999-07-01 00:00:00

abstract：:Arthropod genomes contain sequences derived from integrations of DNA and nonretroviral RNA viruses. These sequences, known as endogenous viral elements (EVEs), have been acquired over the course of evolution and have been proposed to serve as a record of past viral infections. Recent evidence indicates that EVEs can f...

journal_title：Journal of virology

authors： Ter Horst AM,Nigg JC,Dekker FM,Falk BW

更新日期：2019-03-05 00:00:00

abstract：:Alphaviruses represent a serious public health threat and cause a wide variety of diseases, ranging from severe encephalitis, which can result in death or neurological sequelae, to mild infection, characterized by fever, skin rashes, and arthritis. In the infected cells, alphaviruses express only four nonstructural pr...

journal_title：Journal of virology

authors： Gorchakov R,Garmashova N,Frolova E,Frolov I

更新日期：2008-10-01 00:00:00

abstract：:The P4 promoter of the parvovirus minute virus of mice contains a single degenerate GC box sequence which binds the transcription factor Sp1 with high affinity. The two promoters of murine Sp1 were affinity purified, and their interactions with the P4 promoter were examined. Several unusual features were observed. Met...

journal_title：Journal of virology

authors： Pitluk ZW,Ward DC

更新日期：1991-12-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) has evolved multiple strategies for suppression of the antiviral response of the infected cell. DNA array technology has revealed that HCMV clearly regulates host gene expression during the course of a productive infection by enhancing, sustaining, or suppressing steady-state levels of cel...

journal_title：Journal of virology

authors： Gealy C,Denson M,Humphreys C,McSharry B,Wilkinson G,Caswell R

更新日期：2005-01-01 00:00:00

abstract：:Poliovirus (PV) is easily transferred to humans orally; however, no rodent model for oral infections has been developed because of the alimentary tract's low sensitivity to the virus. Here we showed that PV is inactivated by the low pH of the gastric contents in mice. The addition of 3% NaHCO3 to the viral inoculum in...

journal_title：Journal of virology

authors： Ohka S,Igarashi H,Nagata N,Sakai M,Koike S,Nochi T,Kiyono H,Nomoto A

更新日期：2007-08-01 00:00:00

abstract：:Infection by rat virus has been studied in cultures of rat embryo cells to evaluate the Margolis-Kilham hypothesis that the virus preferentially infects tissues with actively dividing cells. An enhancement of infection was seen in cultures infected 10 hr after fresh medium was added as compared to infection of station...

journal_title：Journal of virology

authors： Tennant RW,Layman KR,Hand RE

更新日期：1969-12-01 00:00:00

abstract：:Marek's disease (MD), a highly infectious disease caused by an oncogenic herpesvirus, is one of the few herpesvirus diseases against which live attenuated vaccines are used as the main strategy for control. We have constructed bacterial artificial chromosomes (BACs) of the CVI988 (Rispens) strain of the virus, the mos...

journal_title：Journal of virology

authors： Petherbridge L,Howes K,Baigent SJ,Sacco MA,Evans S,Osterrieder N,Nair V

更新日期：2003-08-01 00:00:00

abstract：:Hepatitis C virus (HCV) often causes a persistent infection associated with hypergammaglobulinemia, high levels of antiviral antibody and circulating immune complexes, and immune complex disease. We previously reported that only a limited neutralizing activity to vesicular stomatitis virus or HCV pseudotype is generat...

journal_title：Journal of virology

authors： Meyer K,Ait-Goughoulte M,Keck ZY,Foung S,Ray R

更新日期：2008-03-01 00:00:00

abstract：:Human respiratory syncytial virus (RSV) is a serious respiratory pathogen in infants and young children as well as elderly and immunocompromised populations. However, no RSV vaccines are available. We have explored the potential of virus-like particles (VLPs) as an RSV vaccine candidate. VLPs composed entirely of RSV ...

journal_title：Journal of virology

authors： McGinnes LW,Gravel KA,Finberg RW,Kurt-Jones EA,Massare MJ,Smith G,Schmidt MR,Morrison TG

更新日期：2011-01-01 00:00:00

abstract：:Both circulating and mucosal antibodies are considered important for protection against infection by influenza virus in humans and animals. However, current inactivated vaccines administered by intramuscular injection using a syringe and needle elicit primarily circulating antibodies. In this study, we report that epi...

journal_title：Journal of virology

authors： Chen D,Periwal SB,Larrivee K,Zuleger C,Erickson CA,Endres RL,Payne LG

更新日期：2001-09-01 00:00:00

abstract：:We show here that the white spot syndrome virus (WSSV) immediate-early protein IE1 interacts with the Penaeus monodon TATA box-binding protein (PmTBP) and that this protein-protein interaction occurs in the absence of any other viral or cellular proteins or nucleic acids, both in vitro and in vivo. Mapping studies usi...

journal_title：Journal of virology

authors： Liu WJ,Chang YS,Huang WT,Chen IT,Wang KC,Kou GH,Lo CF

更新日期：2011-07-01 00:00:00

abstract：:The hepatitis C virus (HCV)-specific CD4+ T-cell response against nonstructural proteins is strongly associated with successful viral clearance during acute hepatitis C. To further develop these observations into peptide-based vaccines and clinical immunomonitoring tools like HLA class II tetramers, a detailed charact...

journal_title：Journal of virology

authors： Gerlach JT,Ulsenheimer A,Grüner NH,Jung MC,Schraut W,Schirren CA,Heeg M,Scholz S,Witter K,Zahn R,Vogler A,Zachoval R,Pape GR,Diepolder HM

更新日期：2005-10-01 00:00:00

abstract：:Purified Friend viruses obtained from chronically infected tissue cultures were studied under the electron microscope in an effort to correlate the fine structure of the particles to their leukemogenic activity under varied experimental conditions, i.e., temperature treatments and exposure to Tween 80, amyl acetate, o...

journal_title：Journal of virology

authors： De Tkaczevski L,De Harven E,Friend C

更新日期：1968-04-01 00:00:00

abstract：:Hepatitis A virus (HAV), an atypical member of the Picornaviridae, grows poorly in cell culture. To define determinants of HAV growth, we introduced a blasticidin (Bsd) resistance gene into the virus genome and selected variants that grew at high concentrations of Bsd. The mutants grew fast and had increased rates of ...

journal_title：Journal of virology

authors： Konduru K,Kaplan GG

更新日期：2010-08-01 00:00:00

abstract：:During the acute phase of infection with influenza A virus, the degree of lymphopenia correlates with severity of disease. Factors that contribute to T-cell activation during influenza virus infection may contribute to this observation. Since the immune response is initiated when dendritic cells (DC) interact with T c...

journal_title：Journal of virology

authors： Oh S,McCaffery JM,Eichelberger MC

更新日期：2000-06-01 00:00:00

abstract：:A unique feature of the large hepadnavirus envelope protein (L) is its mixed transmembrane topology, resulting from partial posttranslational translocation of the pre-S domain. Using protease protection analysis, we demonstrate for duck hepatitis B virus an essential role for the small envelope protein (S) in this pro...

journal_title：Journal of virology

authors： Grgacic EV,Kuhn C,Schaller H

更新日期：2000-03-01 00:00:00

abstract：:Passive transfer of neutralizing antibodies is effective in protecting rhesus macaques against simian/human immunodeficiency virus (SHIV) challenge. In addition to neutralization, effector functions of the crystallizable fragment (Fc) of antibodies are involved in antibody-mediated protection against a number of virus...

journal_title：Journal of virology

authors： Moldt B,Schultz N,Dunlop DC,Alpert MD,Harvey JD,Evans DT,Poignard P,Hessell AJ,Burton DR

更新日期：2011-10-01 00:00:00

abstract：:Examination of the interaction between human immunodeficiency virus (HIV) regulatory gene products and the host immune system is fundamental to understanding the pathogenesis of HIV and could reveal possible targets for therapeutic intervention in the treatment of AIDS. The HIV Tat gene is a potential candidate for th...

journal_title：Journal of virology

authors： Brady HJ,Abraham DJ,Pennington DJ,Miles CG,Jenkins S,Dzierzak EA

更新日期：1995-12-01 00:00:00