Radiation dose dependences in the atomic bomb survivor cancer mortality data: a model-free visualization.

abstract：:It is well established that high-LET radiations efficiently induce chromosome aberrations. However, data on the effect of protons on telomere maintenance, as involved in genomic stability, are scarce and contradictory. Here we demonstrate that high-LET protons induce telomere lengthening in human primary fibroblasts a...

journal_title：Radiation research

authors： Berardinelli F,Antoccia A,Cherubini R,De Nadal V,Gerardi S,Cirrone GA,Tanzarella C,Sgura A

更新日期：2010-11-01 00:00:00

abstract：:The relative biological effectiveness was determined using sex-linked recessive lethals induced in Drosophila spermatozoa as the biological effect. The sex-linked recessive lethal test, a measure of mutations induced in germ cells and transmitted through successive generations, yields a linear dose-response curve in t...

journal_title：Radiation research

authors： Byrne BJ,Lee WR

更新日期：1989-03-01 00:00:00

abstract：:The hyperthermic inhibition of cellular DNA synthesis, i.e., reduction in replicon initiation and delay in DNA chain elongation, was previously postulated to be involved in the induction of chromosomal aberrations believed to be largely responsible for killing S-phase cells. Utilizing asynchronous Chinese hamster ovar...

journal_title：Radiation research

authors： Wong RS,Thompson LL,Dewey WC

更新日期：1988-04-01 00:00:00

abstract：:Radiotherapy is one of the major treatment modalities for the management of various cancers, however, it is limited by the severe side effects and complications experienced by some patients. Nicaraven, a chemically synthesized hydroxyl radical-specific scavenger, has been shown to protect normal tissues from radiation...

journal_title：Radiation research

authors： Yan C,Luo L,Urata Y,Goto S,Guo CY,Li TS

更新日期：2017-02-22 00:00:00

abstract：:Two very different techniques for measuring the energy of neutrons in the energy range 0.1-10 MeV are presented and compared. A recoil-proton spectrometer is used to determine the energy spectra of neutrons produced by the d(4)-Be and p(4)-Be reactions down to the low-energy threshold of 0.7 MeV. The same radiation fi...

journal_title：Radiation research

authors： Folkard M,Makrigiorgos G,Roper MJ,Waker AJ,Michael BD

更新日期：1989-04-01 00:00:00

abstract：:Abstract The present study was undertaken to investigate the ability of dietary supplements to reduce the formation and severity of cataracts in mice irradiated with high-energy protons or iron ions, which are important components of the radiation encountered by astronauts during space travel. The mice were exposed to...

journal_title：Radiation research

authors： Davis JG,Wan XS,Ware JH,Kennedy AR

更新日期：2010-03-01 00:00:00

abstract：:We demonstrate by western analysis that the expression levels of TP53 (formerly known as p53), CDKN1A (formerly known as p21Waf1), CDC2 (formerly known as p34cdc2), CCNB1 (cyclin B1) and RAD51 are significantly modulated in confluent, density-inhibited human diploid cell populations exposed to doses where only a small...

journal_title：Radiation research

authors： Azzam EI,de Toledo SM,Gooding T,Little JB

更新日期：1998-11-01 00:00:00

abstract：:Current therapeutic approaches for treatment of exposure to radiation involve the use of antioxidants, chelating agents, recombinant growth factors and transplantation of stem cells (e.g., hematopoietic stem cell transplantation). However, exposure to high-dose radiation is associated with severe damage to the vascula...

journal_title：Radiation research

authors： Rafii S,Ginsberg M,Scandura J,Butler JM,Ding BS

更新日期：2016-08-01 00:00:00

abstract：:A histopathological study was carried out on the spinal cord of rats after boron neutron capture (BNC) irradiation. Rats were irradiated with thermal neutrons alone or in combination with borocaptate sodium (BSH) or p-boronophenylalanine (BPA). Spinal cords were examined 1 year after irradiation, or at earlier times i...

journal_title：Radiation research

authors： Morris GM,Coderre JA,Bywaters A,Whitehouse E,Hopewell JW

更新日期：1996-09-01 00:00:00

abstract：:Wistar rats (36) were exposed daily throughout pregnancy to a power density level of 35 mW/cm2 of 6000-MHz microwave radiation (11), sham irradiated (10), or used as control animals (15). Litters were culled to a maximum of eight F1a offspring/litter (total = 124) on Postnatal Day 1 and subjected to a series of reflex...

journal_title：Radiation research

authors： Jensh RP

更新日期：1984-02-01 00:00:00

abstract：:The flow cytometry mutation assay is based on detecting mutations in the CD59 gene on human chromosome 11 in CHO A(L) cells with flow cytometry, but the kinetics of mutant expression and the histogram region for mutant selection have not been studied in detail. CHO A(L) cells were analyzed by flow cytometry for CD59 e...

journal_title：Radiation research

authors： Ross CD,Fox MH

更新日期：2008-11-01 00:00:00

abstract：:Currently, there is a serious absence of pharmaceutically attractive small molecules that mitigate the lethal effects of an accidental or intentional public exposure to toxic doses of ionizing radiation. Moreover, cellular systems that emulate the radiobiologically relevant cell populations and that are suitable for h...

journal_title：Radiation research

authors： Zellefrow CD,Sharlow ER,Epperly MW,Reese CE,Shun T,Lira A,Greenberger JS,Lazo JS

更新日期：2012-09-01 00:00:00

abstract：:Braun, R. D., Lanzen, J. L., Turnage, J. A., Rosner, G. and Dewhirst, M. W. Effects of the Interaction between Carbogen and Nicotinamide on R3230 Ac Tumor Blood Flow in Fischer 344 Rats. Radiat. Res. 155, 724-733 (2001). The purpose of this study was to determine whether there are interactions between carbogen breathi...

journal_title：Radiation research

authors： Braun RD,Lanzen JL,Turnage JA,Rosner G,Dewhirst MW

更新日期：2001-05-01 00:00:00

abstract：:Information on early internal radiation doses in Fukushima after the nuclear power plant accident on March 11, 2011, is quite limited due to initial organizational difficulties, high background radiation and contamination of radiation measuring devices. In Nagasaki, approximately 1,200 km away from Fukushima, the inte...

journal_title：Radiation research

authors： Matsuda N,Kumagai A,Ohtsuru A,Morita N,Miura M,Yoshida M,Kudo T,Takamura N,Yamashita S

更新日期：2013-06-01 00:00:00

abstract：:The increasingly wider use of microdosimetry in fields other than pure radiobiological research, especially in "practical" domains such as radiation protection and medical physics, has created a number of new practitioners who are not fully acquainted with many of the experimental pitfalls which beset the aspiring mic...

journal_title：Radiation research

authors： Kliauga P

更新日期：1990-10-01 00:00:00

abstract：:The present study demonstrates the usefulness of immunochemical assays for quantitating modified bases in oxidized and X-irradiated DNA. Escherichia coli, phi X174 RF I, PM2, and M13 DNA containing thymine glycols introduced by OsO4 oxidation were used as antigens in a direct enzyme-linked immunosorbent assay (ELISA)....

journal_title：Radiation research

authors： Hubbard K,Huang H,Laspia MF,Ide H,Erlanger BF,Wallace SS

更新日期：1989-05-01 00:00:00

abstract：:The retention of 241Am in mice 48 h after administration by gavage is reported here. The 241Am was given to mice in the form of either 241Am nitrate or 241Am citrate. The 241Am was also injected into rats in the same form. The homogenized livers of those rats were subsequently administered by gavage to another group o...

journal_title：Radiation research

authors： Hisamatsu S,Takizawa Y

更新日期：1987-08-01 00:00:00

abstract：:To determine whether systemic administration of MnSOD-PL protected mice from the acute hematopoietic syndrome and delayed death after total-body irradiation (TBI), C57BL/ 6J mice were injected intravenously with 100 microl liposomes containing 100 microg of human MnSOD-transgene plasmid 24 h prior to irradiation with ...

journal_title：Radiation research

authors： Epperly MW,Dixon T,Wang H,Schlesselman J,Franicola D,Greenberger JS

更新日期：2008-10-01 00:00:00

abstract：:Nuclear protein and DNA content of HeLa cells was determined as a function of time following hyperthermia by staining isolated nuclei with two fluorescent dyes: fluorescein isothiocyanate (FITC) for protein content and propidium iodide (PI) for DNA content. Bivariate FITC and PI histograms were obtained by flow cytome...

journal_title：Radiation research

authors： Roti Roti JL,Uygur N,Higashikubo R

更新日期：1986-08-01 00:00:00

abstract：:The purpose of this paper is to validate a metabolic model describing the kinetics of tritium in man. The validation is based on measurements of background levels of loose and bound tritium in Italian subjects and their diets. Model predictions are compared with empirical measurements of tritium in human urine and tis...

journal_title：Radiation research

authors： Travis CC,Etnier EL,Hetrick DM

更新日期：1984-12-01 00:00:00

abstract：:The (11)B(p,alpha)(8)Be* nuclear reaction was assessed for its ability to quantitatively map the in vivo subcellular distribution of boron within gliosarcomas treated with a boronated neutron capture therapy agent. Intracranial 9L gliosarcomas were produced in Fischer 344 rats. Fourteen days later, the majority of the...

journal_title：Radiation research

authors： Bench G,Grant PG,Ueda DL,Autry-Conwell SA,Hou Y,Boggan JE

更新日期：2003-12-01 00:00:00

abstract：:The investigation of fragment length distributions of plasmid DNA gives insight into the influence of localized energy distribution on the induction of DNA damage, particularly the clustering of double-strand breaks. We present an approach that determines the fragment length distributions of plasmid DNA after heavy-io...

journal_title：Radiation research

authors： Elsässer T,Brons S,Psonka K,Scholz M,Gudowska-Nowak E,Taucher-Scholz G

更新日期：2008-06-01 00:00:00

abstract：:This study investigated the biological effects and adaptive responses induced by single and repeated in vivo computed tomography (CT) scans. We postulated that, through the induction of low-level oxidative stress, repeated low-dose CT scans (20 mGy, 2 days/week, 10 weeks) could protect mice (C57BL/6) from acute effect...

journal_title：Radiation research

authors： Phan N,De Lisio M,Parise G,Boreham DR

更新日期：2012-02-01 00:00:00

abstract：:This study was undertaken to determine if structural alterations of the bulk chromatin and the amount of protein associated with the nuclear matrix in cerebellar neurons depend on radiation dose and a cell's state of oxygenation. After irradiation with 2.5 to 25.0 Gy under both aerobic and anoxic conditions, the sensi...

journal_title：Radiation research

authors： Jaberaboansari A,Landis MR,Wallen CA,Wheeler KT

更新日期：1989-07-01 00:00:00

abstract：:To estimate the effect of 50 Hz magnetic-field exposure on genome-wide gene expression, the yeast Saccharomyces cerevisiae was used as a model for eukaryotes. 2D PAGE (about 1,000 spots) for protein and cDNA microarray (about 5,900 genes) analysis for mRNA were performed. The cells were exposed to 50 Hz vertical magne...

journal_title：Radiation research

authors： Nakasono S,Laramee C,Saiki H,McLeod KJ

更新日期：2003-07-01 00:00:00

abstract：:Acute thermotolerance was induced in Chinese hamster ovary cells by heating at 43 degrees C for 45 min followed by incubation at 37 degrees C for up to 85 h. The degree of thermotolerance induced was quantified by a second heat exposure at 43 degrees C. To study the interaction of thermotolerance and thermosensitizati...

journal_title：Radiation research

authors： Jung H

更新日期：1994-09-01 00:00:00

abstract：:We present theoretical arguments to explain observations of a "reversal" of the RBE at relatively large doses; that is, the RBE of high-LET vs low-LET radiation is less than one. Numerical examples are given and the results of Bogo et al. (Radiat. Res. 118, 341-352, 1989) are discussed qualitatively. ...

journal_title：Radiation research

authors： Zaider M,Rossi HH

更新日期：1992-04-01 00:00:00

abstract：:While the link between risk of leukemia and acute radiation exposure is well established for large doses received acutely, uncertainty remains around the translation of these risk estimates to occupational exposure scenarios where the doses are low and accumulated over time, possibly over many years. We present leukem...

journal_title：Radiation research

authors： Gillies M,Haylock R,Hunter N,Zhang W

更新日期：2019-11-01 00:00:00

abstract：:Cells from an infinite-life-span near-diploid human fibroblast cell strain, MSU-1.1, were transformed after a single exposure to 60Co gamma radiation. The frequency of transformation as measured by the number of induced foci per 10(6) cells was a linear function of dose. Cells from 13 independent foci from gamma-irrad...

journal_title：Radiation research

authors： O'Reilly S,Walicka M,Kohler SK,Dunstan R,Maher VM,McCormick JJ

更新日期：1998-11-01 00:00:00

abstract：:Neurons are essential components of neural circuits and provide brain function organization. We previously reported that X irradiation induces apoptosis in immature neurons. To the best of our knowledge, there have been few reports investigating the effects of X irradiation on mature neurons. We analyzed the effects o...

journal_title：Radiation research

authors： Shirai K,Mizui T,Suzuki Y,Okamoto M,Hanamura K,Yoshida Y,Hino M,Noda SE,Al-jahdari WS,Chakravarti A,Shirao T,Nakano T

更新日期：2013-06-01 00:00:00