Abstract:
:The increasingly wider use of microdosimetry in fields other than pure radiobiological research, especially in "practical" domains such as radiation protection and medical physics, has created a number of new practitioners who are not fully acquainted with many of the experimental pitfalls which beset the aspiring microdosimetrist. This paper attempts to review some of the lesser known experimental obstacles. It also presents first results of measurements of single-event spectra at nanometer site sizes, based on the use of a small (0.5 x 0.5 mm) counter. Some observations and a critique of the operation of this counter are also presented. It is shown that the counter produces spectra at 5 nm which can be compared with theoretical predictions grounded on fundamental avalanche theory for a cylindrical counter.
journal_name
Radiat Resjournal_title
Radiation researchauthors
Kliauga Psubject
Has Abstractpub_date
1990-10-01 00:00:00pages
S5-15issue
1 Suppleissn
0033-7587issn
1938-5404journal_volume
124pub_type
杂志文章abstract::To compare the effects of exposure to a near-resonant frequency of microwaves at two orientations with a higher frequency exposure, five rhesus monkeys were exposed for 4 hr to 225 MHz, electric field oriented parallel to the long axis of the body (225 MHz-E), and to 225 MHz, magnetic field orientation (225 MHz-H), or...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1985-04-01 00:00:00
abstract::The purpose of this work was to determine how fractionated radiation used in the treatment of tumors affects the ability of cancer as well as normal cells to repair induced DNA double-strand breaks (DSBs) and how cells that have lost this ability die. Lymphocytic leukemia cells (MOLT4) were used as an experimental mod...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/RR2478.1
更新日期:2011-06-01 00:00:00
abstract::Radiation exposure from a number of terrestrial sources is associated with an increased risk for atherosclerosis. Recently, concern over whether exposure to cosmic radiation might pose a similar risk for astronauts has increased. To address this question, we examined the effect of 2 to 5 Gy iron ions ((56)Fe), a parti...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/RR2482.1
更新日期:2011-06-01 00:00:00
abstract::A standard Fricke dosimeter was used to measure the absorbed dose via the oxidation yields of Fe3+ ions in an aqueous environment induced by soft X rays within the "water window" spectral range. We also exploited the property of a neutral solution containing terephthalic acid as a tool for selective detection of OH ra...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/RR15520.1
更新日期:2020-04-01 00:00:00
abstract::Serum copper concentration was evaluated as an index of lung injury (monitored by lung prostacyclin production) with respect to the effects of time, dose, dose fractionation, and penicillamine dose modification in rats irradiated to the right hemithorax. Both lung PGI2 production and serum Cu concentration increased w...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1988-06-01 00:00:00
abstract::As a follow-up to the two previous surveys of radiation therapy among the atomic bomb survivors, a large-scale survey was performed to document (1) the number of radiation therapy treatments received by the atomic bomb survivors and (2) the types of radiation treatments conducted in Hiroshima and Nagasaki. The previou...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract::In a patient with Morbus Hodgkin, structural aberrations of the chromosome type in peripheral lymphocytes were analyzed during radiation therapy (accumulated target dose 44.6 Gy: 22 fractions of 1.8 Gy each and 2 fractions of 2.5 Gy each at the end of the therapy). The blood was sampled about 5 min after a fraction an...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1988-06-01 00:00:00
abstract::Blockers of the renin-angiotensin-aldosterone system (RAAS) ameliorate cognitive deficits and some aspects of brain injury after whole-brain irradiation. We investigated whether treatment with the angiotensin II type 1 receptor antagonist L-158,809 at a dose that protects cognitive function after fractionated whole-br...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/rr2560.1
更新日期:2011-07-01 00:00:00
abstract::An induction-type radiofrequency generator was used to heat thigh implants of the VX2 rabbit carcinoma. The tumor temperature could be easily raised to over 50 degrees C, while the temperature of normal adjacent muscle generally remained at about 43 degrees C. The marked hypovascularity of the tumor, as demonstrated a...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1983-02-01 00:00:00
abstract::Mycoplasma infection of mammalian cells in culture is a common occurrence that can affect the results of experimental protocols. Current methods of eliminating mycoplasma from cell cultures are usually tedious, time-consuming, and sometimes unsuccessful. In the present study, four cultured brain tumor cell lines (huma...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract::Pulse radiolysis and 60Co gamma radiolysis were used to study the effects of ionizing radiations on the activity of glutamate dehydrogenase. Hydroxyl radicals are considerably more effective than hydrated electrons in causing loss of enzymatic activity. Evidence is also presented that the free radical anions (SCN)-.2,...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Exposure to ionizing radiation alone or combined with traumatic tissue injury is a crucial life-threatening factor in nuclear and radiological incidents. Radiation injuries occur at the molecular, cellular, tissue and systemic levels; their mechanisms, however, remain largely unclear. Exposure to radiation combined wi...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/RR14647.1
更新日期:2017-11-01 00:00:00
abstract::This review was initiated in response to concerns that ionizing radiation could be a cause of melanoma. Studies presenting the relative risks for melanoma after external ionizing radiation exposure were in seven categories: (1) The Canadian Radiation Dose Registry, (2) nuclear industry workers, (3) subjects near nucle...
journal_title:Radiation research
pub_type: 杂志文章,评审
doi:10.1667/rr3447.1
更新日期:2005-11-01 00:00:00
abstract::The analysis of mitotic indices (MI) and chromosome breakages in metaphases of 50-hr lymphocyte cultures exposed to the calcium or zinc chelates of diethylenetriamine pentaacetic acid (DTPA) demonstrated: (1) an 80% reduction in MI in cultures from three women but no reduction in those from two men after in vitro expo...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1984-07-01 00:00:00
abstract::To determine whether exposure to radiofrequency (RF) radiation can induce DNA damage or apoptosis, Molt-4 T lymphoblastoid cells were exposed with RF fields at frequencies and modulations of the type used by wireless communication devices. Four types of frequency/modulation forms were studied: 847.74 MHz code-division...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/rr3127
更新日期:2004-02-01 00:00:00
abstract::The capacity of plateau-phase Chinese hamster V79 and normal and transformed C3H-10T1/2 cells for repair of potentially lethal radiation damage (PLD) was evaluated for cells irradiated alone or given combined treatments of heat and radiation. The data show that all cell lines tested could repair PLD and that transform...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::There is growing scientific, regulatory and public concern over anthropogenic input of radionuclides to the aquatic environment, especially given the issues surrounding existing nuclear waste, future energy demand and past or potential nuclear accidents. A change in the approach to how we protect the environment from ...
journal_title:Radiation research
pub_type: 杂志文章,评审
doi:10.1667/rr2687.1
更新日期:2012-05-01 00:00:00
abstract::Currently available treatments for radiation-induced nausea and vomiting either are ineffective or reduce performance. The new antiemetic and gastrokinetic agent zacopride was tested in rhesus monkeys to assess its behavioral toxicity and its ability to inhibit radiation-induced emesis. Zacopride (intragastric, 0.3 mg...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
abstract::Radiation exposure leads to a risk for long-term deterministic and stochastic late effects. Two individuals exposed to protracted photon radiation in the radiological accident at the Lilo Military site in Georgia in 1997 received follow-up treatment and resection of several chronic radiation ulcers in the Bundeswehr H...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/RR0774.1
更新日期:2007-05-01 00:00:00
abstract::The linear no-threshold extrapolation from a dose-response relationship for ionizing radiation derived at higher doses to doses for which regulatory standards are proposed is being challenged by some scientists and defended by others. It appears that the risks associated with exposures to doses of interest are below t...
journal_title:Radiation research
pub_type:
doi:
更新日期:1998-12-01 00:00:00
abstract::Trypanothione is a unique diglutathionyl-spermidine conjugate found in abundance in trypanosomes but not in other eukaryotes. Because trypanothione is a naturally occurring polyamine thiol reminiscent of the synthetic drug amifostine, it may be a useful protector against radiation and oxidative stress. For these reaso...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/RR2235.1
更新日期:2010-09-01 00:00:00
abstract::A biophysical model has been developed that is based on the assumptions that an interphase chromosome occupies a spherical territory and that chromosome exchanges are formed by the misrejoining of two DNA double-strand breaks induced within a defined interaction distance. The model is used to explain the relative freq...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/0033-7587(2001)156[0603:poriia]2.0.co;2
更新日期:2001-11-01 00:00:00
abstract::Chinese hamster ovary (CHO) cells were exposed to various concentrations of diethylmaleate (DEM) during a 42 degrees C incubation to determine if glutathione (GSH) compartmentalization was a factor in modification of thermal sensitivity. Cytoplasmic and mitochondrial GSH were isolated from CHO cells immediately after ...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
abstract::While the risk of lung cancer associated separately with smoking and radiation exposure has been widely reported, it is not clear how smoking and radiation together contribute to the risk of specific lung cancer histological types. With individual smoking histories and radiation dose estimates, we characterized the jo...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/rr2819.1
更新日期:2012-09-01 00:00:00
abstract::This paper evaluates the global vitamin D effective UV (UV(vitd)) irradiances under cloudy conditions at a subtropical, southern hemisphere site. The UV(vitd) irradiances were analyzed on a horizontal plane and sampled at 5-min intervals over 18 months so that a wide range of parameters including cloud conditions, sol...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/RR1936.1
更新日期:2010-05-01 00:00:00
abstract::The relative biological effectiveness was determined using sex-linked recessive lethals induced in Drosophila spermatozoa as the biological effect. The sex-linked recessive lethal test, a measure of mutations induced in germ cells and transmitted through successive generations, yields a linear dose-response curve in t...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::To characterize the role of the cerebrovascular response in the development of brain injury after focal irradiation, 125I sources were implanted in frontal white matter of the brain of normal dogs; dose was 20 Gy, 7.5 mm from the source. Cerebral blood flow, vascular volume and mean transit time of blood were quantifi...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract::The adaptive response to ionizing radiation may be mediated by the induction of antioxidant defense mechanisms, accelerated repair or altered cell cycle progression after the conditioning dose. To gain new insight into the mechanism of the adaptive response, nondividing lymphocytes and fibroblasts were used to elimina...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/rr3430.1
更新日期:2005-10-01 00:00:00
abstract::It is well known that ionizing radiation-induced toxicity to normal tissue has functional consequences in the brain. However, the underlying molecular alterations have yet to be elucidated. We have previously reported cognitive impairments with concomitant changes in dendritic complexity, spine density and inflammatio...
journal_title:Radiation research
pub_type: 杂志文章
doi:10.1667/RR15061.1
更新日期:2018-11-01 00:00:00
abstract::To approach treatment of micrometastases of steroid receptor-rich cancers using estrogen receptor-directed therapy with Auger electrons, multicellular spheroids of the estrogen receptor-rich human breast cancer cell line, MCF-7, were prepared and exposed to a range of concentrations of an Auger electron-emitting estro...
journal_title:Radiation research
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00