Cooperative phenomena in two-pulse, two-color laser photocoagulation of cutaneous blood vessels.

Abstract:

:A novel laser system has been developed to study the effects of multiple laser pulses of differing wavelengths on cutaneous blood vessels in vivo, using the hamster dorsal skin flap preparation and in vitro, using cuvettes of whole or diluted blood. The system permits sequenced irradiation with well-defined intrapulse spacing at 532 nm, using a long-pulse frequency-doubled Nd:YAG laser, and at 1064 nm, using a long-pulse Nd:YAG laser. Using this system, we have identified a parameter space where two pulses of different wavelengths act in a synergistic manner to effect permanent vessel damage at radiant exposures where the two pulses individually have little or no effect. Using a two-color pump-probe technique in vitro, we have identified a phenomenon we call greenlight-induced infrared absorption, where a pulse of green light causes photochemical and photothermal modifications to the chemical constituents of blood and results in enhanced infrared absorption. We identify a new chemical species, met-hemoglobin, not normally present in healthy human blood but formed during laser photocoagulation which we believe is implicated in the enhanced near-infrared absorption.

journal_name

Photochem Photobiol

authors

Barton JK,Frangineas G,Pummer H,Black JF

doi

10.1562/0031-8655(2001)073<0642:cpitpt>2.0.co;2

subject

Has Abstract

pub_date

2001-06-01 00:00:00

pages

642-50

issue

6

eissn

0031-8655

issn

1751-1097

journal_volume

73

pub_type

杂志文章
  • Chlorin e6 derivative radachlorin mainly accumulates in mitochondria, lysosome and endoplasmic reticulum and shows high affinity toward tumors in nude mice in photodynamic therapy.

    abstract::The efficacy of photodynamic therapy (PDT) depends upon the amount of photosensitizer accumulated in the malignant tissues. Radachlorin is a popular photosensitizer used in photodynamic therapy to treat various types of cancer. In this study, we have studied the main organelles responsible for the accumulation of rada...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12273

    authors: Biswas R,Moon JH,Ahn JC

    更新日期:2014-09-01 00:00:00

  • Comparison of methylene blue and methylene violet for photoinactivation of intracellular and extracellular virus in red cell suspensions.

    abstract::Previous studies with methylene blue (MB) in red cell suspensions have demonstrated that extracellular, but not intracellular, virus can be readily photoinactivated. To test if the resistance of intracellular virus to inactivation is related to the permanent positive charge of the phenothiazine, a series of uncharged ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1997.tb08588.x

    authors: Skripchenko A,Robinette D,Wagner SJ

    更新日期:1997-03-01 00:00:00

  • Behaviors producing photodispersal in Stentor coeruleus.

    abstract::The ciliate Stentor coeruleus exhibits photodispersal, that is, these cells swim away from light sources and collect in dimly lighted areas. We imaged and reconstructed the tracks of 48 Stentor to determine which swimming behaviors produced their photodispersal. We observed that their photodispersal is not due to a ch...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2004)080<0401:BPPISC>2.0.CO;2

    authors: Menzies E,Das N,Wood DC

    更新日期:2004-11-01 00:00:00

  • Actinic Prurigo in Singaporean Chinese: A Positive Association with HLA-DRB1*03:01.

    abstract::Studies have reported the association of human leukocyte antigen (HLA) genes with susceptibility to develop actinic prurigo (AP) in Caucasians, but there were no studies in Asian populations, including the Chinese. Our study was performed to determine if AP is associated with susceptibility or protective HLA alleles o...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12569

    authors: Chen Q,Shen M,Heng YK,Theng TSC,Tey HL,Ren EC,Chong WS

    更新日期:2016-03-01 00:00:00

  • Analysis of two kinds of tree as physical barriers against erythemal UVB radiation received.

    abstract::Differences between global radiation UVER (erythemal ultraviolet solar radiation) received under full sun and diffuse radiation received under the shadow of two types of tree are analyzed to check the importance of these components on human exposure to UV radiation. Blue Line spores dosimeters of VioSpor were used for...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12020

    authors: Ysasi GG,Ribera LJ

    更新日期:2013-05-01 00:00:00

  • Enhanced response to daunomycin of normal, tumor and metastatic cell lines via drug photoactivation.

    abstract::We have compared the cytotoxicity of daunomycin in vitro to highly differentiated normal epithelial cells (Fisher rat thyroid cells, FRTL-5) and to two neoplastic cell lines, a thyroid carcinoma (TK-6) and its lung metastasis (MPTK-6). Whereas the cell lines are equally sensitive to the drug in the dark, if irradiated...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1993.tb09223.x

    authors: Andreoni A,Colasanti A,Kisslinger A,Mastrocinque M,Portella G,Riccio P,Roberti G

    更新日期:1993-05-01 00:00:00

  • Calculation of singlet oxygen dose using explicit and implicit dose metrics during benzoporphyrin derivative monoacid ring A (BPD-MA)-PDT in vitro and correlation with MLL cell survival.

    abstract::Photodynamic therapy (PDT) oxygen consumption, clonogenic cell survival, fluorescence photobleaching and photoproduct formation were investigated during benzoporphyrin derivative monoacid (BPD-MA)-PDT of MAT-LyLu cells in vitro. Cells were incubated with BPD-MA concentrations of 0.1, 0.5 or 2.5 μg mL(-1) for 2 h and t...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2011.00942.x

    authors: Weston MA,Patterson MS

    更新日期:2011-09-01 00:00:00

  • Antimicrobial photodynamic therapy and photodynamic inactivation, or killing bugs with dyes and light--a symposium-in-print.

    abstract::In antimicrobial photodynamic therapy, the photosensitizer (PS) in its ground singlet state absorbs light to give the excited singlet state that can transition to the long-lived triplet state. This PS triplet may undergo energy transfer (Type 2) or electron transfer (Type 1) to oxygen to form reactive oxygen species (...

    journal_title:Photochemistry and photobiology

    pub_type: 社论

    doi:10.1111/j.1751-1097.2012.01139.x

    authors: Hamblin MR

    更新日期:2012-05-01 00:00:00

  • Sensitized photooxidation of Di- and tripeptides of tyrosine.

    abstract::This paper studies the dye-sensitized photooxidation of tyrosine (tyr) and tyr di- and tripeptides (tyr-tyr and tyr-tyr-tyr) mediated by singlet molecular oxygen (O2[1 delta g]) in alkaline media. Photooxidation quantum efficiencies (phi r) were obtained by determining the overall and reactive rate constants of intera...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:

    authors: Criado S,Soltermann AT,Marioli JM,García NA

    更新日期:1998-10-01 00:00:00

  • The quenching of CdSe quantum dots photoluminescence by gold nanoparticles in solution.

    abstract::The photoluminescence (PL) of CdSe quantum dots (QD) in aqueous media has been studied in the presence of gold nanoparticles (NP) with different shapes. The steady state PL intensity of CdSe QD (1.5-2 nm in size) is quenched in the presence of gold NP. Picosecond bleach recovery and nanosecond time-resolved luminescen...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2002)075<0591:tqocqd>2.0.co;2

    authors: Nikoobakht B,Burda C,Braun M,Hun M,El-Sayed MA

    更新日期:2002-06-01 00:00:00

  • Carotenohematoporphyrins as tumor-imaging dyes. Synthesis and in vitro photophysical characterization.

    abstract::Multichromophoric dyes for use in tumor imaging have been synthesized and photophysically characterized. Structurally, these dyes are dyads and triads that consist of one or two carotenoid polyenes covalently attached to hematoporphyrin (HP) or hematoporphyrin dimethyl ester (HPDME) moieties via ester linkages. The gr...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:

    authors: Tatman D,Liddell PA,Moore TA,Gust D,Moore AL

    更新日期:1998-10-01 00:00:00

  • Biodistribution and pharmacokinetic studies of a porphyrin dimer photosensitizer (Oxdime) by fluorescence imaging and spectroscopy in mice bearing xenograft tumors.

    abstract::Herein, we present a study of the pharmacokinetics and biodistribution of a butadiyne-linked conjugated porphyrin dimer (Oxdime) designed to have high near-infrared (NIR) 2-photon absorption cross-section for photodynamic therapy (PDT). Changes in biodistribution over time were monitored in mice carrying B16-F10 melan...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2012.01194.x

    authors: Khurana M,Ulrich S,Kim A,Moriyama Y,Netchev G,Akens MK,Anderson HL,Wilson BC

    更新日期:2012-11-01 00:00:00

  • A role for hydrogen peroxide in the pro-apoptotic effects of photodynamic therapy.

    abstract::Although the first reactive oxygen species (ROS) formed during irradiation of photosensitized cells is almost invariably singlet molecular oxygen (1O2), other ROS have been implicated in the phototoxic effects of photodynamic therapy (PDT). Among these are superoxide anion radical (*O2(-)), hydrogen peroxide (H2O2) an...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2009.00589.x

    authors: Price M,Terlecky SR,Kessel D

    更新日期:2009-11-01 00:00:00

  • The hairless mouse model of photoaging: evaluation of the relationship between dermal elastin, collagen, skin thickness and wrinkles.

    abstract::Quantitative and qualitative changes in dermal collagen and elastin occur in response to chronic ultraviolet (UV) irradiation. These changes have been implicated in the genesis of the wrinkling seen in chronically irradiated, or photoaged skin. We examined the relationship between wrinkle formation and changes in derm...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1992.tb02194.x

    authors: Moloney SJ,Edmonds SH,Giddens LD,Learn DB

    更新日期:1992-10-01 00:00:00

  • Sun exposure over a lifetime in Australian adults from latitudinally diverse regions.

    abstract::Spatio-temporal patterns in sun exposure underlie variations in skin cancer incidence and vitamin D deficiency, indicate effectiveness of sun protection programs and provide insights into future health risks. From 558 adults across four regions of Australia (Brisbane (27°S), Newcastle (33°S), Geelong and the Western D...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12044

    authors: Lucas RM,Valery P,van der Mei I,Dwyer T,Pender MP,Taylor B,Ponsonby AL,Ausimmune Investigator Group.

    更新日期:2013-05-01 00:00:00

  • Photooxidative damage to lysosomes of cultured macrophages by acridine orange.

    abstract::Cultured cells accumulate acridine orange (AO), which is a weak basic dye and a photosensitizer, in lysosomes and other acidic compartments. During exposure to blue light, AO-loaded macrophages show decreasing red granular fluorescence and increasing green diffuse fluorescence. This is hypothesized to represent peroxi...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1990.tb01685.x

    authors: Zdolsek JM,Olsson GM,Brunk UT

    更新日期:1990-01-01 00:00:00

  • UV induced (6-4) photoproducts are distributed differently than cyclobutane dimers in nucleosomes.

    abstract::We have compared the distributions of two stable UV photoproducts in nucleosome core DNA at the single-nucleotide level using a T4 polymerase-exonuclease mapping procedure. The distribution of pyrimidine-pyrimidone (6-4) dimers was uncovered by reversing the major UV photo-product, cis-syn cyclobutane pyrimidine dimer...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1990.tb01732.x

    authors: Gale JM,Smerdon MJ

    更新日期:1990-04-01 00:00:00

  • Electrocyclic rearrangement of pentamethylcyclooctapyrimidine-2,4-diones: reaction pathway into a 9,11-diazapentacyclo-[6.4.0.0(1,3).0(2,5).0(4,8)]dodecane system and a 9,11-diazapentacyclo [6.4.0.0(1,3).0(2,6).0(4,8)]dodecane system.

    abstract::Photolysis of 6-chloro-1,3-dimethyluracil and mesitylene in the presence of trifluoroacetic acid (TFA) at low temperature gave 1,3,5,7,9- and 1,3,6,8,10-pentamethylcyclooctapyrimidine-2,4-diones (1b, 1c). Sequential photoreaction of the former (1b) resulted in the formation of 9,11-diazapentacyclo[6.4.0.0(1,3).0(2,5)....

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)074<0385:eropdr>2.0.co;2

    authors: Ohkura K,Nishijima K,Seki K

    更新日期:2001-09-01 00:00:00

  • Triplet Excited States and Singlet Oxygen Production by Analogs of Red Wine Pyranoanthocyanins.

    abstract::During the maturation of red wines, the anthocyanins of grapes are transformed into pyranoanthocyanins, which possess a pyranoflavylium cation as their basic chromophore. Photophysical properties of the singlet and triplet excited states of a series of synthetic pyranoflavylium cations were determined at room temperat...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12973

    authors: Silva GTM,Thomas SS,Silva CP,Schlothauer JC,Baptista MS,Freitas AA,Bohne C,Quina FH

    更新日期:2019-01-01 00:00:00

  • In vitro photodynamic effects of lysyl chlorin p6: cell survival, localization and ultrastructural changes.

    abstract::The in vitro cell survival, localization and ultrastructural changes following irradiation were examined in 9L glioma cells sensitized with a new photosensitizer, lysyl chlorin p6 (LCP). In clonogenic assays, LCP was 10-100-fold more phototoxic than photofrin II on a microgram/mL basis. Lysyl chlorin p6 uptake was blo...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1993.tb04948.x

    authors: Leach MW,Higgins RJ,Autry SA,Boggan JE,Lee SJ,Smith KM

    更新日期:1993-11-01 00:00:00

  • Empirical evaluation of a simple analytical formula for the ultraviolet index.

    abstract::This paper focuses on the estimation of the UV Index (UVI) for all sky conditions using a simple analytical parameterization involving three independent variables: the solar zenith angle, the total ozone column and the clearness index. Measurements of the UVI made at Badajoz and Cáceres (Southwestern Spain) from Janua...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2010.00860.x

    authors: Antón M,Serrano A,Cancillo ML,García JA,Madronich S

    更新日期:2011-03-01 00:00:00

  • New triruthenium clusters as photoinduced DNA-binding and cleaving agents.

    abstract::1-Hydroxybenzotriazole and 1-hydroxypyridine-2-thione were incorporated as ligands with the cluster Ru3(CO)10 (NCMe)2 to give [(mu-H)Ru3(CO)10(mu2-2,3-eta2-NNN(O)C6 H4)] and [(mu-H)Ru3(CO)9(mu2-eta1 : eta2-C5H4N(O)S)], respectively. Irradiation of these two new triruthenium metal clusters individually with 350 nm UV l...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2002)075<0457:ntcapd>2.0.co;2

    authors: Hwu JR,Kuang-Lieh L,Yu SF,Yu LJ,Kumaresan S,Lin KJ,Tsay SC

    更新日期:2002-05-01 00:00:00

  • In vitro study of the photocytotoxicity of some hypericin analogs on different cell lines.

    abstract::In the present study, hypericin analogs with an increased hydrophilic character were synthesized. As chemical modifications alter the lipophilicity/hydrophilicity balance together with the photophysical/chemical background of the molecule the influence of these structural changes on the cellular uptake, retention and ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)074<0164:ivsotp>2.0.co;2

    authors: Delaey EM,Obermuëller R,Zupkó I,De Vos D,Falk H,de Witte PA

    更新日期:2001-08-01 00:00:00

  • Roles of porphyrin and iron metabolisms in the δ-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin and photodamage of tumor cells.

    abstract::δ-Aminolevulinic acid (ALA)-induced porphyrin accumulation is widely used in the treatment of cancer, as photodynamic therapy. To clarify the mechanisms of the tumor-preferential accumulation of protoporphyrin, we examined the effect of the expression of heme-biosynthetic and -degradative enzymes on the ALA-induced ac...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2011.00950.x

    authors: Ohgari Y,Miyata Y,Miyagi T,Gotoh S,Ohta T,Kataoka T,Furuyama K,Taketani S

    更新日期:2011-09-01 00:00:00

  • Comparison of UV-absorbing nets in pepper crops: spectral properties, effects on plants and pest control.

    abstract::In horticultural crops, the use of screens to protect plants is the usual strategy in the Mediterranean area. Screen manufacturers offer a range of netting that vary in their UV-absorbing properties. We compared the photoeffects of seven different screens. Sweet pepper trials were conducted at the Gilat Research Cente...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2009.00657.x

    authors: Legarrea S,Karnieli A,Fereres A,Weintraub PG

    更新日期:2010-03-01 00:00:00

  • In vitro Studies of Antitumor Effect, Toxicity/Cytotoxicity and Skin Permeation/Retention of a Green Fluorescence Pyrene-based Dye for PDT Application.

    abstract::Photosensitizers (PS) are compounds that can generate reactive oxygen species under irradiation of appropriate light and are widely used in photodynamic therapy (PDT). Currently, topical PDT is an effective treatment for several skin diseases, including bacterial infections, fungal mycoses and psoriasis. In addition, ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13335

    authors: de França BM,Ghasemishahrestani Z,de Souza GFM,da Silva RN,Queiroz DD,Pierre MBR,Pereira MD,Forero JSB,Corrêa RJ

    更新日期:2020-09-23 00:00:00

  • Alkali-labile photolesions mapping to purine sites in ultraviolet-irradiated DNA.

    abstract::Gel sequencing experiments with the 5'- and 3'-end-labeled oligonucleotides d(A3GA4GA5GA6GA3G) and d(AT)10 have demonstrated that dimeric adenine photoproducts and thymine-adenine photoadducts constitute alkali-labile lesions in UV-irradiated DNA. On treatment with hot piperidine, DNA strand breakage occurs predominan...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1994.tb05022.x

    authors: Hejmadi V,Stevenson C,Kumar S,Davies RJ

    更新日期:1994-02-01 00:00:00

  • Ultraviolet B but not A radiation activates suppressor B cells in draining lymph nodes.

    abstract::Immunosuppressive doses of solar-simulated UV radiation activate lymph node B cells that can suppress primary immunity by inhibiting the function of dendritic cells. The aim of this study was to determine the waveband responsible for activation of these suppressor B cells. We exposed C57BL/6 mice to various doses of e...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2005-04-20-RA-495

    authors: Byrne SN,Ahmed J,Halliday GM

    更新日期:2005-11-01 00:00:00

  • Photocatalytic degradation of toluene using a novel flow reactor with Fe-doped TiO2 catalyst on porous nickel sheets.

    abstract::A novel continuous-flow photocatalytic reactor was designed to decompose toluene by using porous nickel sheets that were coated with a Fe-doped TiO2 catalyst. While locating the UV lamp at the central axis, the catalyst sheets were located along the inner wall and positioned vertically with an equal space of 50 mm alo...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2004-06-19-RA-207

    authors: Dezhi S,Sheng C,Chung JS,Xiaodong D,Zhibin Z

    更新日期:2005-03-01 00:00:00

  • Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer.

    abstract::Ultraviolet (UV) radiation is among the most prevalent environmental factors that influence human health and disease. Even 1 h of UV irradiation extensively damages the genome. To cope with resulting deleterious DNA lesions, cells activate a multitude of DNA damage response pathways, including DNA repair. Strikingly, ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13245

    authors: Lee JW,Ratnakumar K,Hung KF,Rokunohe D,Kawasumi M

    更新日期:2020-05-01 00:00:00