Neurosecretory activity within suprachiasmatic neurons of the female rabbit following castration.

abstract：:The known occurrence of opiates in the adrenals stimulated us to determine whether Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2), an endogenous peptide that can act as an antiopiate, is present in these glands and whether adrenalectomy affects its concentrations in plasma. The presence of Tyr-MIF-1 in the adrenals of the rat was sh...

journal_title：Neuroendocrinology

authors： Kastin AJ,Fabre L,Banks WA,Zadina JE

更新日期：1993-03-01 00:00:00

abstract：:Recordings were made of single unit activity through chronically implanted electrodes within the hypothalamic paraventricular nucleus of freely moving male rats also bearing chronically implanted stimulating electrodes in the preoptic area (POA) and indwelling jugular cannulae. High frequency electrical stimulation of...

journal_title：Neuroendocrinology

authors： Saphier D,Feldman S

更新日期：1986-01-01 00:00:00

abstract：:Over the last 10 years, kisspeptins--peptide products of varying lengths encoded by the KISS1 gene--have been found to be key regulators of normal reproductive function throughout life in animals and humans. By activating the kisspeptin receptor [previously known as orphan G protein-coupled receptor 54 (GPR54)], they ...

journal_title：Neuroendocrinology

authors： Prague JK,Dhillo WS

更新日期：2015-01-01 00:00:00

abstract：:Acetylcholinesterase (AChE) activity, and concentrations of monoamines, monoamine metabolites and oxytocin (OT) were measured in the cerebrospinal fluid (CSF) of sheep during late pregnancy, labour, parturition, vaginocervical stimulation, lamb separation and suckling. Concentrations of AChE, 4-hydroxy-3 methoxyphenyl...

journal_title：Neuroendocrinology

authors： Kendrick KM,Keverne EB,Baldwin BA,Sharman DF

更新日期：1986-01-01 00:00:00

abstract：:The involvement of histaminergic transmission in the rapid and sustained plasma ACTH and corticosterone (CORT) responses induced in conscious rats by intra-arterial infusions of 25 micrograms.kg-1 Escherichia coli lipopolysaccharide (LPS) was investigated. LPS challenge produced a rapid and transient increase (+ 62%) ...

journal_title：Neuroendocrinology

authors： Givalois L,Siaud P,Mekaouche M,Ixart G,Malaval F,Assenmacher I,Barbanel G

更新日期：1996-03-01 00:00:00

abstract：:There is a great deal of conflicting data regarding the issue of whether androgens influence opiate receptors in the whole male rat brain. Although Hahn and Fishman initially reported that long-term castration produced a large increase in the density of opiate-binding sites, relative to controls, no other independent ...

journal_title：Neuroendocrinology

authors： Cicero TJ,O'Connor LH,Bell RD

更新日期：1987-08-01 00:00:00

abstract：:Pit-1 expression has been reported to be cell-type-specific in the adult human pituitary and in human pituitary adenomas. In contrast, studies of rodent fetal adenohypophysial development as well as mature rodent glands have indicated that the pit-1 mRNA is ubiquitously expressed and the protein is under translational...

journal_title：Neuroendocrinology

authors： Puy LA,Asa SL

更新日期：1996-04-01 00:00:00

abstract：:Allopregnanolone is a neuroactive steroid present in the brain, but also measurable in systemic circulation. It exhibits anxiolytic and anticonvulsant effects and is able to produce hyperphagia. Since eating behavior disturbances and increased peripheral basal sympathetic activity have been reported in obese subjects,...

journal_title：Neuroendocrinology

authors： Menozzi R,Florio P,Bondi M,Luisi S,Cobellis L,Genazzani AR,Del Rio G,Petraglia F

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. AIM:To evaluate the clinicopathological features and therapeutic outcomes of CP diagnosed in the elderly. PATIENTS AND METHODS:A retrospective, multicenter, national study of C...

journal_title：Neuroendocrinology

authors： Iglesias P,Nocete I,Moure Rodríguez MD,Venegas-Moreno E,Ares J,Biagetti B,Rodríguez Berrocal V,Guerrero-Pérez F,Vicente A,Villar-Taibo R,Cordido F,Paja M,Glerean M,González Rivera N,Dios Fuentes E,Blanco C,Alvaréz-Escolá

更新日期：2020-10-09 00:00:00

abstract：:The mechanisms involved in the activation of the hypothalamus-pituitary-adrenal axis after administration of Mycoplasma fermentans were examined. Male rats were injected intracerebroventricularly (i.c.v.) with heat-inactivated M. fermentas (6 micrograms protein/10 microliters/rat) or vehicle and were killed 2 h later....

journal_title：Neuroendocrinology

authors： Wohlman A,Gallily R,Yirmiya R,Weidenfeld J

更新日期：1997-09-01 00:00:00

abstract：:Parturition is initiated in sheep by an increase in the activity of the fetal hypothalamus-pituitary-adrenal (HPA) axis. Prostaglandins, known to augment the activity of this endocrine axis, have long been proposed as involved in the initiation of paturition. We have previously demonstrated that endogenously produced ...

journal_title：Neuroendocrinology

authors： Deauseault D,Giroux D,Wood CE

更新日期：2000-05-01 00:00:00

abstract：:Delta-sleep-inducing peptide (DSIP) colocalizes within gonadotropin-releasing-hormone (GnRH)-containing neurons in adult hypothalamus and could play a role in the regulation of hypothalamic-pituitary axis in adults. To support the possibility that DSIP also participates in fetal neuroendocrine events and to demonstrat...

journal_title：Neuroendocrinology

authors： Pu LP,Dubois PM

更新日期：1992-01-01 00:00:00

abstract：:After in vivo treatment, progesterone initially decreases tyrosine hydroxylase (TH) activity in the TIDA neurons, but subsequently increases TH activity with prolonged treatment. In order to explore the cellular mechanism for progesterone's effect, this study examined the acute inhibitory action of progesterone on TH ...

journal_title：Neuroendocrinology

authors： Arbogast LA,Voogt JL

更新日期：2002-05-01 00:00:00

abstract：:Endocrine pancreatic tumours (EPTs) are uncommon, with a major challenge to alert physicians to their recognition and requirements of treatment. Functioning EPTs cause well-known clinical syndromes of hormone excess. Insulinomas, gastrinomas and glucagonomas are most common; vipomas and somatostatinomas are rare. EPTs...

journal_title：Neuroendocrinology

authors： Akerström G,Hellman P,Hessman O,Osmak L

更新日期：2004-01-01 00:00:00

abstract：:Serum prolactin was measured in lightly etherized rats between 4 and 5 a.m. and between 11 a.m. and 12 noon at various times after operation in intact rats and rats that had been operated on. Serum prolactin was elevated in the late nocturnal samples from intact rats and this elevation was prevented by pinealectomy. W...

journal_title：Neuroendocrinology

authors： Ronnekleiv OK,McCann SM

更新日期：1975-01-01 00:00:00

abstract：:In vivo and in vitro methods have been used to compare the effects of opioid receptor blockade on the functional activity of the hypothalamo-pituitary-gonadal axis in adult (200 g) and sexually immature (50 g) male rats. In the adult, a single injection of the mu-receptor antagonist, naloxone (500 micrograms/100 g bod...

journal_title：Neuroendocrinology

authors： Leposavic G,Cover PO,Buckingham JC

更新日期：1991-06-01 00:00:00

abstract：:Oxytocin (OT) binding sites are modulated by estrogens in several brain regions including the ventromedial hypothalamic nucleus (VMN) in both male and female rats. To further study steroid regulation of OT receptor binding, we examined the effect of androgen replacement in castrated male rats on OT binding with quanti...

journal_title：Neuroendocrinology

authors： Johnson AE,Coirini H,McEwen BS,Insel TR

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:We previously presented data of this multicentric, phase II study showing that everolimus plus octreotide long-acting repeatable (LAR) for advanced neuroendocrine neoplasms (NENs), in the first line setting, is an active and safe treatment. We now present updated data at 5 years. METHODS:Patients with advan...

journal_title：Neuroendocrinology

authors： Bajetta E,Catena L,Pusceddu S,Spada F,Iannacone C,Sarno I,Di Menna G,Dottorini L,Marte AM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:68Gallium DOTA-PET imaging is preferable to standard somatostatin receptor scintigraphy where available; however, its role in the management of lung carcinoid tumours (LC) remains unclear. METHODS:All consecutive patients with histologically confirmed LC from two ENETS Centres of Excellence were identified ...

journal_title：Neuroendocrinology

authors： Lamarca A,Pritchard DM,Westwood T,Papaxoinis G,Nonaka D,Vinjamuri S,Valle JW,Manoharan P,Mansoor W

更新日期：2018-01-01 00:00:00

abstract：:We studied the effect that beta-endorphin (beta END) might have at the median eminence (ME) on luteinizing hormone (LH)-releasing hormone (LHRH) during the ovulatory cycle of domestic hens. Thus, we assessed (a) the immunocytochemical distribution of beta END and LHRH in the hen ME, (b) the temporal changes in ME and ...

journal_title：Neuroendocrinology

authors： Contijoch AM,Malamed S,Sarkar DK,Advis JP

更新日期：1993-01-01 00:00:00

abstract：:The role of endogenous opiate peptides in the mesencephalic central gray (MCG) and their possible interactions with gonadotropin-releasing hormone (GnRH) in the regulation of lordosis behavior was assessed in ovariectomized, estrogen-treated and estrogen-progesterone-treated female rats. Lordosis behavior triggered by...

journal_title：Neuroendocrinology

authors： Sirinathsinghji DJ

更新日期：1984-09-01 00:00:00

abstract：:Thyroid hormones and nitric oxide/cyclic guanosine monophosphate (NO/cGMP) signaling play a significant role in the structural development of the cerebellum, respectively. In the present study, the possible contribution of neuronal NO synthase (NOS) and cGMP in the thyroid hormone-induced structural changes was invest...

journal_title：Neuroendocrinology

authors： Serfozo Z,de Vente J,Elekes K

更新日期：2009-01-01 00:00:00

abstract：:Serotonin and dopamine neurons have been shown to exert a stimulatory and inhibitory control, respectively, over pituitary release of beta-endorphin-like immunoreactivity (beta-END-LI). In the present study we sought to determine whether an interaction exists between these two reciprocal mechanisms regulating beta-END...

journal_title：Neuroendocrinology

authors： Sapun-Malcolm D,Farah JM Jr,Mueller GP

更新日期：1986-01-01 00:00:00

abstract：:Follicle-stimulating hormone (FSH) is involved in the regulation and maintenance of gametogenesis. It exists in multiple molecular forms with different oligosaccharide structures which in turn are influenced by the hormonal milieu. Previous studies from our laboratory demonstrated that antiandrogen administration to i...

journal_title：Neuroendocrinology

authors： Rulli SB,Creus S,Pellizzari E,Cigorraga SB,Calandra RS,Campo S

更新日期：1999-10-01 00:00:00

abstract：:Kisspeptin is a neuropeptide that signals via a Gαq-coupled receptor, GPR54, in gonadotropin-releasing hormone (GnRH) neurons and is essential for pubertal maturation and fertility. Kisspeptin depolarizes and excites GnRH neurons primarily through the activation of canonical transient receptor potential (TRPC) channel...

journal_title：Neuroendocrinology

authors： Rønnekleiv OK,Zhang C,Bosch MA,Kelly MJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cervical stimulation induces a circadian rhythm of prolactin secretion and antiphase dopamine release. The suprachiasmatic nucleus (SCN) controls this rhythm, and we propose that it does so through clock gene expression within the SCN. METHODS:To test this hypothesis, serial blood samples were taken fr...

journal_title：Neuroendocrinology

authors： Poletini MO,Kennett JE,McKee DT,Freeman ME

更新日期：2010-01-01 00:00:00

abstract：:Galanin-like peptide (GALP) is a 60-amino-acid peptide with structural similarities to galanin and a high affinity for galanin receptors. GALP is expressed by a discrete population of neurons in the arcuate nucleus (ARC) and median eminence of the hypothalamus of several species, including the rat. GALP neurons expres...

journal_title：Neuroendocrinology

authors： Shen J,Gundlach AL

更新日期：2004-01-01 00:00:00

abstract：:Using specific antibodies to corticotrophin-releasing factor (CRF) and arginine vasopressin (AVP) we have immunocytochemically located cells and fibres containing these peptides in sheep fetuses. CRF neurones were first detected, in low frequency, in the paraventricular nuclei of fetuses of 90 days of gestation (term ...

journal_title：Neuroendocrinology

authors： Levidiotis M,Oldfield B,Wintour EM

更新日期：1987-11-01 00:00:00

abstract：:Although glutamate is the predominant excitatory amino acid in the vertebrate central nervous system (CNS) where it affects a variety of physiological processes and pathophysiological states, the role that glutamate receptors may play outside the CNS has not been clearly established. In the present study, the effects ...

journal_title：Neuroendocrinology

authors： Giovannucci DR,Stuenkel EL

更新日期：1995-08-01 00:00:00

abstract：:The ability of the flutamide metabolite Sch 16423 to block androgen receptor binding and inhibit masculine copulatory behavior in male rats was examined. Restoration of copulatory behavior was prevented in Sch 16423-treated rats given two 10-mm testosterone (T)-filled Silastic capsules plus 15 mg Sch 16423 daily for 1...

journal_title：Neuroendocrinology

authors： McGinnis MY,Mirth MC

更新日期：1986-01-01 00:00:00