Involvement of central histamine in the early phase of ACTH and corticosterone responses to endotoxin in rats.

abstract：:After the combined treatment with dexamethasone, morphine and pentobarbitone, the electrical stimulation in the rat tuber cinereum induces a rise in plasma corticosterone (CS) level, probably by direct stimulation of the corticoliberin-producing neural elements and the consecutive ACTH release. We have attempted to lo...

journal_title：Neuroendocrinology

authors： Makara GB,Stark E,Palkovits M

更新日期：1978-01-01 00:00:00

abstract：:Avian prolactin (PRL) secretion is regulated by vasoactive intestinal peptide (VIP) neurons residing in the infundibular nuclear complex (INF) of the hypothalamus. This VIPergic activity is modulated by stimulatory dopaminergic inputs. Dynorphin, serotonin (5-HT), dopamine (DA) and VIP all appear to stimulate PRL secr...

journal_title：Neuroendocrinology

authors： Youngren O,Chaiseha Y,Al-Zailaie K,Whiting S,Kang SW,El Halawani M

更新日期：2002-03-01 00:00:00

abstract：:These studies investigated the effect of aging on thyroid hormone regulation of beta-endorphin in rat corpus striatum and hypothalamus. In both brain areas, basal levels of beta-endorphin declined with age. In addition, age modified the response of beta-endorphin to thyroid hormone status. Hypothyroid rats aged 6 mont...

journal_title：Neuroendocrinology

authors： Gambert SR

更新日期：1981-02-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP) gene transcripts were demonstrated by RNA blot hybridization using VIP-specific RNA hybridization probes. High levels of expression were observed as early as in 16-day-old embryos. In aging rats, the VIP-mRNA levels were reduced significantly (in the cerebral cortex) as compared to ...

journal_title：Neuroendocrinology

authors： Gozes I,Schächter P,Shani Y,Giladi E

更新日期：1988-01-01 00:00:00

abstract：:The presence of vasopressin (VP) in pars distalis of rats and pigs was investigated. Using radioimmunoassay and bioassay of VP, a substance with immunological and biological properties of this hormone was found. This substance was not detected in the adenohypophysis of rats with diabetes insipidus. A partial purificat...

journal_title：Neuroendocrinology

authors： Chateau M,Marchetti J,Burlet A,Boulange M

更新日期：1979-01-01 00:00:00

abstract：:The functions of oxytocin in the female are thought to be confined to the processes of milk ejection and parturition. In this study the role of oxytocin in the body's response to stressful stimuli has been examined. Physical immobilization of rats and forced swimming caused large increases in the secretion of the horm...

journal_title：Neuroendocrinology

authors： Lang RE,Heil JW,Ganten D,Hermann K,Unger T,Rascher W

更新日期：1983-10-01 00:00:00

abstract：:The effect of steroids on the two gonadotropin-releasing hormone (GnRH) forms present in the eel (mammalian GnRH, mGnRH and chicken GnRH-II, cGnRH-II), as well as on gonadotropin (GTH), was studied using specific radioimmunoassays. Female silver eels received chronic treatments with various steroids (estradiol, testos...

journal_title：Neuroendocrinology

authors： Montero M,Le Belle N,King JA,Millar RP,Dufour S

更新日期：1995-05-01 00:00:00

abstract：:The effect of sonicated suspensions of phosphatidylserine (PS), an acidic phospholipid, was investigated on prolactin secretion utilizing in vivo and in vitro approaches. Acute and chronic administration of PS reduced plasma prolactin levels during different phases of circadian rhythms. The phospholipid was able to in...

journal_title：Neuroendocrinology

authors： Canonico PL,Annunziato L,Toffano G,Bernardini R,Stanzani S,Foti M,Clementi G,Drago F,Scapagnini U

更新日期：1981-12-01 00:00:00

abstract：:The study was designed to determine whether the ability of central oxytocin (OT) to stimulate gonadotropin-releasing hormone (GnRH) on the afternoon of proestrus (PE) in the cycling female rat is mediated at the level of GnRH terminals within the median eminence (ME), or at higher hypothalamic levels where GnRH cell b...

journal_title：Neuroendocrinology

authors： Selvage D,Johnston CA

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:We previously presented data of this multicentric, phase II study showing that everolimus plus octreotide long-acting repeatable (LAR) for advanced neuroendocrine neoplasms (NENs), in the first line setting, is an active and safe treatment. We now present updated data at 5 years. METHODS:Patients with advan...

journal_title：Neuroendocrinology

authors： Bajetta E,Catena L,Pusceddu S,Spada F,Iannacone C,Sarno I,Di Menna G,Dottorini L,Marte AM

更新日期：2018-01-01 00:00:00

abstract：:In this study, radiolabeled recombinant rat interleukin-1 beta (r125I-IL-1 beta) was used to localize and characterize IL-1 beta binding in rat hypothalamus and pituitary gland by quantitative autoradiography. The ability of this ligand to bind to type I IL-1 receptor was first tested on murine lymphoma cells (EL-4). ...

journal_title：Neuroendocrinology

authors： Marquette C,Van Dam AM,Ban E,Lanièce P,Crumeyrolle-Arias M,Fillion G,Berkenbosch F,Haour F

更新日期：1995-10-01 00:00:00

abstract：:Hereditary cases of growth hormone (GH)-secreting tumors have been classified into three clinical entities: the multiple endocrine neoplasia type 1 (MEN1) syndrome, the Carney complex (CNC) and the isolated familial somatotropinomas (IFS). The genomic defects associated with MEN1 are all linked to various mutations of...

journal_title：Neuroendocrinology

authors： Lytras A,Tolis G

更新日期：2006-01-01 00:00:00

abstract：:Recordings were made of single unit activity through chronically implanted electrodes within the hypothalamic paraventricular nucleus of freely moving male rats also bearing chronically implanted stimulating electrodes in the preoptic area (POA) and indwelling jugular cannulae. High frequency electrical stimulation of...

journal_title：Neuroendocrinology

authors： Saphier D,Feldman S

更新日期：1986-01-01 00:00:00

abstract：:The neuropeptide galanin (GAL) is widely distributed in the central and peripheral nervous systems where it often coexists with catecholamines and acetylcholine. Recently we have reported that human GAL (hGAL) in man depresses the release of norepinephrine (NE) and the responses to both assumption of upright posture a...

journal_title：Neuroendocrinology

authors： degli Uberti EC,Bondanelli M,Margutti A,Ambrosio MR,Valentini A,Campo M,Franceschetti P,Zatelli MC,Pansini R,Trasforini G

更新日期：1996-11-01 00:00:00

abstract：:Histamine (HA) stimulates the release of the pro-opiomelanocortin (POMC)-derived peptides ACTH, beta-endorphin (beta-END), beta-lipotropin and alpha-melanocyte-stimulating hormone, and HA is involved in the mediation of the stress-induced release of these peptides. The effect of HA is indirect and may involve the hypo...

journal_title：Neuroendocrinology

authors： Kjaer A,Knigge U,Bach FW,Warberg J

更新日期：1992-09-01 00:00:00

abstract：:Introduction The membrane-associated G protein-coupled estrogen receptor 1 (GPER) mediates the regulation by estradiol on arginine-vasopressin immunoreactivity in the supraoptic and paraventricular hypothalamic nuclei of female rats and is involved in the estrogenic control of hypothalamic regulated functions, such as...

journal_title：Neuroendocrinology

authors： Marraudino M,Carrillo B,Bonaldo B,Llorente R,Campioli E,Garate I,Pinos H,Garcia-Segura LM,Collado P,Grassi D

更新日期：2020-06-22 00:00:00

abstract：:Several molecular forms related to the decapeptide LHRH were characterized and quantified in various brain structures of intact and castrated male and female rats. Distinct moieties were separated by high performance liquid chromatography (HPLC) and radioimmunoassayed against anti-LHRH antibodies of different specific...

journal_title：Neuroendocrinology

authors： Gautron JP,Pattou E,Leblanc P,L'Héritier A,Kordon C

更新日期：1993-08-01 00:00:00

abstract：:The sleep-wakefulness pattern and brain protein levels were determined in rats for 3 h following these conditions: administration of an inhibitor of protein synthesis (anisomycin), administration of several doses of rat growth hormone (GH) or thyrotropin, and administration of a combination of anisomycin + GH or thyro...

journal_title：Neuroendocrinology

authors： Drucker-Colín RR,Spanis CW,Hunyadi J,Sassin JF,McGaugh JL

更新日期：1975-01-01 00:00:00

abstract：:Brain corticosteroid receptors, the type 1 mineralocorticoid receptor (MR) and the type 2 glucocorticoid receptor (GR), are involved in the regulation of neuroendocrine and behavioral responses during ongoing and stressful conditions. To further investigate the role of MR in these responses, we treated male Wistar rat...

journal_title：Neuroendocrinology

authors： Reul JM,Probst JC,Skutella T,Hirschmann M,Stec IS,Montkowski A,Landgraf R,Holsboer F

更新日期：1997-03-01 00:00:00

abstract：:The expression of the alpha-subunit of the glycoprotein hormones was studied in the developing rat pituitary by in situ hybridization and immunocytochemical techniques. The alpha-subunit mRNA labelling was detected in Rathke's pouch at 12 days' gestation (E12); at E13, it was exclusively concentrated in the pars tuber...

journal_title：Neuroendocrinology

authors： Stoeckel ME,Hindelang C,Klein MJ,Poissonnier M,Félix JM

更新日期：1993-12-01 00:00:00

abstract：:Medial parvocellular paraventricular corticotropin-releasing hormone (mPVN CRH) cells are critical in generating hypothalamic-pituitary-adrenal (HPA) axis responses to systemic interleukin-1beta (IL-1beta). However, although it is understood that catecholamine inputs are important in initiating mPVN CRH cell responses...

journal_title：Neuroendocrinology

authors： Buller K,Xu Y,Dayas C,Day T

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND/AIM:Somatostatin (SST) analogs are mainstay for controlling tumor proliferation and hormone secretion in carcinoid patients. Recent data suggest that extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation may potentiate the anti-tumor effects of SST analogs in carcinoids. Additionally, ERK1/2 pho...

journal_title：Neuroendocrinology

authors： Somnay Y,Chen H,Kunnimalaiyaan M

更新日期：2013-01-01 00:00:00

abstract：:The in vitro release of LHRH from hypothalami of adult male rats (intact, 5-day castrates, 5-day castrates replaced with various doses of testosterone) was measured under basal conditions and after the addition of KCl, the opiate antagonist naloxone or the opiate agonist DAGO to the perifusion medium. Hypothalami from...

journal_title：Neuroendocrinology

authors： Nikolarakis KE,Pfeiffer DG,Almeida OF,Herz A

更新日期：1986-01-01 00:00:00

abstract：:We have investigated the variations in growth hormone (GH) and somatostatin (SOM) mRNAs in adult, middle-aged and aging rats of both sexes using quantitative in situ hybridization. cDNA probes complementary to GH mRNA and SOM mRNA were used on fixed pituitary and hypothalamic sections, respectively. A clear sexual dim...

journal_title：Neuroendocrinology

authors： Martinoli MG,Ouellet J,Rhéaume E,Pelletier G

更新日期：1991-12-01 00:00:00

abstract：:The neurohypophysial peptide hormone [Arg8]vasopressin (AVP) has well documented pressor effects in the periphery. These are mediated by vasopressin receptors (VPRs) of the V1a subtype, expressed by vascular smooth muscle cells, which induce vascular contraction when activated. AVP also has effects on the vasculature ...

journal_title：Neuroendocrinology

authors： Sermasi E,Howl J,Pyner S,Wheatley M,Coote JH

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:The reviewing and assessment of epidemiological characteristics of neuroendocrine tumours (NETs) remains a challenge. Despite the fact that it is an uncommon family of neoplasms, several worldwide series have revealed an increasing incidence of this rare condition. However, the data are difficult to compare ...

journal_title：Neuroendocrinology

authors： Huguet I,Grossman AB,O'Toole D

更新日期：2017-01-01 00:00:00

abstract：:Changes in antidiuretic substance (i.e., vasopressin) release from the cut pituitary stalk and the intact pituitary gland were observed during electrical stimulation of amygdala medial nucleus. Electrical pulses of 4 or 36 cycles per second (cps) were used and in both cases the same energy (about 2.160 nanowatt second...

journal_title：Neuroendocrinology

authors： Tomas T

更新日期：1975-01-01 00:00:00

abstract：:The mechanisms involved in the activation of the hypothalamus-pituitary-adrenal axis after administration of Mycoplasma fermentans were examined. Male rats were injected intracerebroventricularly (i.c.v.) with heat-inactivated M. fermentas (6 micrograms protein/10 microliters/rat) or vehicle and were killed 2 h later....

journal_title：Neuroendocrinology

authors： Wohlman A,Gallily R,Yirmiya R,Weidenfeld J

更新日期：1997-09-01 00:00:00

abstract：:Studies were performed to determine the role of thyroid hormone in the suppression of thyrotropin (TSH) by opiates. Serum samples were collected by decapitation 1, 3, 6, 12, 24, or 48 h after rats were implanted with 1 sustained-release morphine (75 mg) or placebo pellet. Morphine decreased TSH by 44% at 1 h and by 83...

journal_title：Neuroendocrinology

authors： Berglund LA,Millard WJ,Gabriel SM,Simpkins JW

更新日期：1990-09-01 00:00:00

abstract：:Thymic neuroendocrine neoplasms are rare tumours, but their management can often be highly problematic. While previously assumed to be essentially variants of bronchopulmonary (lung) carcinoids, they are generally more aggressive and more difficult to treat. Some 25% are associated with multiple endocrine neoplasia-1,...

journal_title：Neuroendocrinology

authors： Jia R,Sulentic P,Xu JM,Grossman AB

更新日期：2017-01-01 00:00:00