Vasoactive intestinal peptide gene expression from embryos to aging rats.

abstract：:The effect of glucocorticoids on corticotropin-releasing factor (CRF) gene expression was studied by combination of in situ hybridization histochemistry and steroid implantation. Dexamethasone micropellets, implanted around the hypothalamic paraventricular nucleus (PVN), caused total inhibition of the hybridizable CRF...

journal_title：Neuroendocrinology

authors： Kovács KJ,Mezey E

更新日期：1987-10-01 00:00:00

abstract：:Brain corticosteroid receptors, the type 1 mineralocorticoid receptor (MR) and the type 2 glucocorticoid receptor (GR), are involved in the regulation of neuroendocrine and behavioral responses during ongoing and stressful conditions. To further investigate the role of MR in these responses, we treated male Wistar rat...

journal_title：Neuroendocrinology

authors： Reul JM,Probst JC,Skutella T,Hirschmann M,Stec IS,Montkowski A,Landgraf R,Holsboer F

更新日期：1997-03-01 00:00:00

abstract：:We have used excitatory amino acids as tools to elucidate changes in hypothalamic function associated with lactation, focusing on the regulation of luteinizing hormone (LH) and prolactin secretion. In these studies, we have compared the responsiveness to NMA (N-methyl-D,L-aspartate), an agonist for the N-methyl-D-aspa...

journal_title：Neuroendocrinology

authors： Abbud R,Smith MS

更新日期：1993-10-01 00:00:00

abstract：:Studies were conducted to determine if the hypothermic effects of barbiturates were responsible for their ability to suppress luteinizing hormone (LH) secretion in rats following ovariectomy or treatment with gonadal steroids. In both ovariectomized rats and rats treated with estradiol and progesterone, pentobarbital ...

journal_title：Neuroendocrinology

authors： Simpkins JW,Katovich MJ

更新日期：1987-09-01 00:00:00

abstract：:In these three experiments, we investigated the effect of adrenalectomy and adrenal demedullation on the stress-induced impairment of long-term potentiation (LTP) in the rat hippocampal slice. In the first, adrenalectomy alone resulted in a significant reduction in LTP, while exposure to stress resulted in a further r...

journal_title：Neuroendocrinology

authors： Shors TJ,Levine S,Thompson RF

更新日期：1990-01-01 00:00:00

abstract：:An influence of thyroid status on the secretory activity of hypothalamic dopaminergic neurons was observed in adult rats and its involvement in the regulation of prolactin (PRL) secretion was examined. The secretory activity of the tuberoinfundibular dopaminergic (TIDA) neurons was evaluated by measurement of dopamine...

journal_title：Neuroendocrinology

authors： Reymond MJ,Benotto W,Lemarchand-Béraud T

更新日期：1987-06-01 00:00:00

abstract：:In addition to the magnocellular hypothalamic nuclei, arginine vasopressin (AVP)-containing neurons have also been identified in limbic structures, including the hippocampus and amygdala. In the present study, we compared the qualitative properties of the in vitro release of AVP from the dissected hypothalamus with th...

journal_title：Neuroendocrinology

authors： Raber J,Pich EM,Koob GF,Bloom FE

更新日期：1994-03-01 00:00:00

abstract：:Leptin, the product of the obese gene, is a protein that is secreted primarily from adipocytes. Leptin can influence the function of the pituitary gland through its action on the hypothalamus, but it can also directly act at the level of the pituitary gland. The ability of leptin to induce an increase in intracellular...

journal_title：Neuroendocrinology

authors： Glavaski-Joksimovic A,Rowe EW,Jeftinija K,Scanes CG,Anderson LL,Jeftinija S

更新日期：2004-01-01 00:00:00

abstract：:Characteristic increases in neuronal activity coincident with the pulsatile release of luteinizing hormone from the pituitary gland have been recorded from electrodes chronically implanted in the medial basal hypothalamus of the rhesus monkey. This electrophysiologic manifestation of the hypothalamic 'pulse generator'...

journal_title：Neuroendocrinology

authors： Wilson RC,Kesner JS,Kaufman JM,Uemura T,Akema T,Knobil E

更新日期：1984-09-01 00:00:00

abstract：:The effect of frontal deafferentation of the medial basal hypothalamus on pro-opiomelanocortin (POMC) gene expression was studied in the intermediate lobe (IL) and anterior lobe (AL) of the pituitary gland in the absence and presence of corticosterone (CORT). The lesion in the basal hypothalamus removed neural inputs ...

journal_title：Neuroendocrinology

authors： Seger MA,van Eekelen JA,Kiss JZ,Burbach JP,de Kloet ER

更新日期：1988-04-01 00:00:00

abstract：:Circadian rhythms occur in hypothalamic serotonin content in the turkey. Inhibition of serotonin (5-HT) synthesis by parachlorophenylalanine (PCPA) blocks circadian variation in hypothalamic serotonin levels suggesting that the major cause of diurnal fluctuations is differing rates of synthesis of the amine. PCPA trea...

journal_title：Neuroendocrinology

authors： Martin JT,El Halawani M,Phillips RE

更新日期：1982-03-01 00:00:00

abstract：:Our previous studies on annexin 5, a member of the annexin family of proteins, have shown its expression in the anterior pituitary gland, its preferential distribution in gonadotropes, and its increase after ovariectomy. In the present study, we examined (1) whether annexin 5 is synthesized in gonadotropes, (2) whethe...

journal_title：Neuroendocrinology

authors： Kawaminami M,Etoh S,Miyaoka H,Sakai M,Nishida M,Kurusu S,Hashimoto I

更新日期：2002-01-01 00:00:00

abstract：:Acute immobilization stress results in changes in the concentration of both dopamine and noradrenaline in specific forebrain limbic system areas, whereas the adrenaline levels remain unchanged. Changes in dopamine concentrations are more restricted than those in noradrenaline concentrations. Dopamine levels are increa...

journal_title：Neuroendocrinology

authors： Saavedra JM

更新日期：1982-11-01 00:00:00

abstract：:Vasostatin, a fragment of calreticulin, was transfected in the BON cell line to evaluate the feasibility of using it for gene therapy in neuroendocrine tumors. Vasostatin transfected cells were subcutaneously inoculated in nude mice. Burkitt lymphoma cell line, CA46, colorectal adenocarcinoma cell line, SW480, as well...

journal_title：Neuroendocrinology

authors： Liu M,Imam H,Oberg K,Zhou Y

更新日期：2005-01-01 00:00:00

abstract：:To examine the role of excitatory amino acid neurotransmitters in the regulation of LH and FSH secretion in ovariectomized (ovx) adult rats treated with estradiol and progesterone, we measured the release rates of the excitatory amino acid neurotransmitters, glutamate and aspartate, as well as the neurally inactive am...

journal_title：Neuroendocrinology

authors： Ping L,Mahesh VB,Wiedmeier VT,Brann DW

更新日期：1994-04-01 00:00:00

abstract：:We have previously reported that the somatotropin regulatory peptides, growth hormone-releasing hormone (GRF) and somatostatin (SS) increase feeding when applied centrally in low picomole-range doses. The similarity between the dose-response characteristics and photoperiod sensitivities of these two peptide's feeding ...

journal_title：Neuroendocrinology

authors： Feifel D,Vaccarino FJ,Rivier J,Vale WW

更新日期：1993-01-01 00:00:00

abstract：:Arginine-vasopressin (AVP) is regarded as a potent stimulator of pituitary adrenocorticotropin (ACTH) secretion and participates therefore in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis function in concert with the physiological activator of the axis, hypothalamic corticotropin-releasing hormone (C...

journal_title：Neuroendocrinology

authors： Bernardini R,Chiarenza A,Kamilaris TC,Renaud N,Lempereur L,Demitrack M,Gold PW,Chrousos GP

更新日期：1994-11-01 00:00:00

abstract：:The mechanisms involved in the activation of the hypothalamus-pituitary-adrenal axis after administration of Mycoplasma fermentans were examined. Male rats were injected intracerebroventricularly (i.c.v.) with heat-inactivated M. fermentas (6 micrograms protein/10 microliters/rat) or vehicle and were killed 2 h later....

journal_title：Neuroendocrinology

authors： Wohlman A,Gallily R,Yirmiya R,Weidenfeld J

更新日期：1997-09-01 00:00:00

abstract：:Recent evidence suggests that the free amino-terminal fragment of procalcitonin (N-PCT) plays a role in the central control of feeding behavior and energy homeostasis. However, little is known about the mechanisms through which N-PCT works. Here we report that intracerebroventricular administration of N-PCT to free-fe...

journal_title：Neuroendocrinology

authors： Tavares E,Miñano FJ

更新日期：2008-01-01 00:00:00

abstract：:Neurons synthesizing growth hormone releasing factor were detected by immunocytochemistry with specific antiserum against synthetic rat hypothalamic growth hormone releasing factor. Growth hormone releasing factor immunoreactive neurons which also showed tyrosine hydroxylase immunoreactivity were located in the ventro...

journal_title：Neuroendocrinology

authors： Okamura H,Murakami S,Chihara K,Nagatsu I,Ibata Y

更新日期：1985-08-01 00:00:00

abstract：:Pregnant rats were kept on an ethanol-containing (6% w/v) liquid diet from the 13th day of gestation and serum growth hormone (GH) levels were determined in the offspring after four different experimental paradigms. In controls, administration of cyproheptadine (a serotonin-blocking agent), or insulin, or exposure to ...

journal_title：Neuroendocrinology

authors： Thadani PV

更新日期：1984-04-01 00:00:00

abstract：:Gonadal steroids exert an important regulatory influence upon the biosynthetic and secretory activity of the somatostatin and growth hormone-releasing hormone (GHRH) neurons controlling the release of growth hormone. It is hypothesized that some of these effects occur in an indirect transsynaptic manner through the st...

journal_title：Neuroendocrinology

authors： Pannell C,Simonian SX,Gillies GE,Luscher B,Herbison AE

更新日期：2002-08-01 00:00:00

abstract：:To clarify the role and site of action of gamma-aminobutyric acid (GABA) in ovine pineal glands, we have investigated the effects of aminooxyacetic acid (AOAA), an inhibitor of GABA transaminase, on endogenous GABA content and beta-adrenoceptor mediated pineal function in Merino sheep. A significant elevation of endog...

journal_title：Neuroendocrinology

authors： Foldes A,Maxwell CA,Rintoul AJ,Edols RW

更新日期：1984-03-01 00:00:00

abstract：:We have investigated the effects of exposure to short-term constant light (LL) on the spontaneous, proestrous luteinizing hormone (LH) surge in the female rat. Exposure to LL during the 3 days preceding proestrus delayed and reduced the magnitude of the LH surge which was measured in blood samples taken from conscious...

journal_title：Neuroendocrinology

authors： Watts AG,Fink G

更新日期：1981-09-01 00:00:00

abstract：:In previous studies we obtained evidence that serotonin release by p-chloroamphetamine (PCA) causes an increase in corticosterone secretion but that this effect is not mediated via the raphe nuclei in the midbrain. In contrast, PCA-induced prolactin secretion was abolished by dorsal raphe lesions. In the present study...

journal_title：Neuroendocrinology

authors： Van de Kar LD,Karteszi M,Bethea CL,Ganong WF

更新日期：1985-11-01 00:00:00

abstract：:The hypophysial portal vessels and anterior pituitary glands of adult male rats were surgically exposed, cannulated and infused for 1 min with saline, growth hormone-releasing factor (GH-RF), and dbcAMP. After cessation of infusion, anterior pituitary glands were collected at 1, 5, 15, 30 or 60 min for electron micros...

journal_title：Neuroendocrinology

authors： Wilbur DL,Worthington WC Jr,Markwald RR

更新日期：1975-01-01 00:00:00

abstract：:Somatotropes and GC cells, a GH-producing cell line, exhibit [Ca(2+)](i) oscillations that result from rhythmic Ca(2+) action potentials. Determination of this operating mode required simultaneous recording of both parameters by fura-2 imaging and patch-clamp techniques. In order to test whether patch recording induce...

journal_title：Neuroendocrinology

authors： Robert C,Tseeb V,Kordon C,Hammond C

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Little information is available concerning prognostic factors for bronchopulmonary large cell neuroendocrine carcinomas (BP-LCNECs) and even less is known about combined LCNECs (Co-LCNECs). We investigated whether an integrated morphological, immunohistochemical, and molecular approach could be used for thei...

journal_title：Neuroendocrinology

authors： Milione M,Maisonneuve P,Grillo F,Mangogna A,Centonze G,Prinzi N,Pusceddu S,Garzone G,Cattaneo L,Busico A,Bossi P,Spaggiari P,Pellegrinelli A,Del Gobbo A,Ferrero S,Kankava K,Pruneri G,Rolli L,Roca E,Bercich L,Tiron

更新日期：2020-05-04 00:00:00

abstract：:Studies were undertaken to determine the effects of chronic stimulation of opiate receptors on the negative feedback effects of testosterone (T) on luteinizing hormone (LH) secretion in the male rat. In an initial study, castrated male rats received replacement levels of T (2 ng/ml) or chronic morphine (M) treatment f...

journal_title：Neuroendocrinology

authors： Gabriel SM,Simpkins JW,Kalra SP,Kalra PS

更新日期：1985-01-01 00:00:00

abstract：:The role of endogenous opioid peptides in the control of gonadotropin-releasing hormone pulse generator activity was examined in long-term ovariectomized goats by recording the hypothalamic multiple-unit activity specifically associated with pulsatile luteinizing hormone secretion (MUA volleys). Administration of nalo...

journal_title：Neuroendocrinology

authors： Ito K,Tanaka T,Mori Y

更新日期：1993-04-01 00:00:00