Vasoactive intestinal peptide gene expression from embryos to aging rats.

abstract：:The accuracy and reproducibility of the World Health Organization (WHO) 2015 classification of bronchopulmonary neuroendocrine neoplasms (BP-NENs) is disputed. The aim of this study is to classify and grade BP-NENs using the WHO 2019 classification of digestive system NENs (DiS-NEN-WHO 2019), and to analyze its accura...

journal_title：Neuroendocrinology

authors： Oka N,Kasajima A,Konukiewitz B,Sakurada A,Okada Y,Kameya T,Weichert W,Ishikawa Y,Suzuki H,Sasano H,Klöppel G

更新日期：2020-01-01 00:00:00

abstract：:Although glutamate is the predominant excitatory amino acid in the vertebrate central nervous system (CNS) where it affects a variety of physiological processes and pathophysiological states, the role that glutamate receptors may play outside the CNS has not been clearly established. In the present study, the effects ...

journal_title：Neuroendocrinology

authors： Giovannucci DR,Stuenkel EL

更新日期：1995-08-01 00:00:00

abstract：:The effect of glucocorticoids on corticotropin-releasing factor (CRF) gene expression was studied by combination of in situ hybridization histochemistry and steroid implantation. Dexamethasone micropellets, implanted around the hypothalamic paraventricular nucleus (PVN), caused total inhibition of the hybridizable CRF...

journal_title：Neuroendocrinology

authors： Kovács KJ,Mezey E

更新日期：1987-10-01 00:00:00

abstract：:Lewis (LEW) and Fischer 344 (F344) rats differ in responsiveness of the hypothalamo-pituitary-adrenocortical (HPA) axis as well as in their behavioral responses to drugs of abuse. The present experiments were conducted to compare hypothalamic corticotropin-releasing factor (CRF), plasma adrenocorticotropic hormone (AC...

journal_title：Neuroendocrinology

authors： Simar MR,Saphier D,Goeders NE

更新日期：1996-01-01 00:00:00

abstract：:A role for glutamate in signalling mechanisms in the mammalian pineal gland is suggested by the high concentration of the transmitter in pinealocytes and the expression of glutamate receptor subunits in the rat gland. A single type of glutamate binding site has been characterized in the rat and bovine pineal gland, pr...

journal_title：Neuroendocrinology

authors： Mick G

更新日期：1995-03-01 00:00:00

abstract：:Kisspeptin is a neuropeptide that signals via a Gαq-coupled receptor, GPR54, in gonadotropin-releasing hormone (GnRH) neurons and is essential for pubertal maturation and fertility. Kisspeptin depolarizes and excites GnRH neurons primarily through the activation of canonical transient receptor potential (TRPC) channel...

journal_title：Neuroendocrinology

authors： Rønnekleiv OK,Zhang C,Bosch MA,Kelly MJ

更新日期：2015-01-01 00:00:00

abstract：:During adult-onset peripheral hypothyroidism, the brain maintains normal levels of thyroid hormone for some time through a mechanism of 'central homeostasis'. Although onset, duration, and termination of such a homeostatic phenomenon have been recently evaluated in rat models, the mechanism behind remains unknown. Dur...

journal_title：Neuroendocrinology

authors： Kundu S,Roy S,De J,Biswas A,Pramanik M,Ray AK

更新日期：2007-01-01 00:00:00

abstract：:G-protein-coupled receptor 135 (GPCR135), a former orphan GPCR also known as SALPR, has recently been shown to be modulated by relaxin-3 (R3). In addition to GPCR135, R3 has been shown to be an agonist for GPCR142 (which is a pseudogene in the rat) and to activate LGR7, which is primarily the receptor for relaxin-1/2....

journal_title：Neuroendocrinology

authors： Sutton SW,Bonaventure P,Kuei C,Roland B,Chen J,Nepomuceno D,Lovenberg TW,Liu C

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Manipulating thyroid hormones has been shown to influence learning and memory. Although a large body of literature is available on the effects of thyroid hormone deficiency on learning and memory functions during developmental or adult-onset hypothyroidism, electrophysiological findings are limited. This lim...

journal_title：Neuroendocrinology

authors： Taşkın E,Artis AS,Bitiktas S,Dolu N,Liman N,Süer C

更新日期：2011-01-01 00:00:00

abstract：:We have previously reported that luteinizing hormone releasing hormone (LH-RH) levels in the medial basal hypothalamus (MBH) of adult male rats castrated for 2 weeks can be raised by testosterone (T) or estradiol (E2) treatment for 3-4 days. The present study was undertaken to determine the time after castration when ...

journal_title：Neuroendocrinology

authors： Kalra PS

更新日期：1985-09-01 00:00:00

abstract：:Using two tests in intact adult rats, it has been found that a high positive correlation exists (p less than 0.005) between the ovulation inhibiting and the serotonin antagonistic activities measured in vivo of five tricyclic compounds and ten ergot derivatives. In these chemically different classes of compounds, cert...

journal_title：Neuroendocrinology

authors： Markó M,Flückiger E

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND/AIMS:Estrogen receptor-alpha (ER alpha) splice variants are important for understanding estrogen effects on the brain and estrogen therapy pitfalls. We addressed the question whether a novel ER alpha splice variant TADDI is expressed at the protein level in the human brain and whether it changes in relation ...

journal_title：Neuroendocrinology

authors： Ishunina TA,Swaab DF

更新日期：2009-01-01 00:00:00

abstract：:The effects of acute and chronic administration of a combination of lynestrenol-mestrenol, a widely employed contraceptive medication, on the dopaminergic system of the rat forebrain and striatum were investigated to better understand the biochemical basis of the neurological side-effects of steroid contraceptive drug...

journal_title：Neuroendocrinology

authors： Algeri S,Ponzio F,Dolfini E,Jori A

更新日期：1976-01-01 00:00:00

abstract：:The effects of delta 9-tetrahydrocannabinol (THC) on hypothalamic norepinephrine (NE) and dopamine (DA) turnover and hypothalamic serotonin (5-HT), 5-hydroxyindole acetic acid (5-HIAA) and LHRH content preceding and during a progesterone- (P) induced LH and prolactin (PRL) surge were investigated in ovariectomized est...

journal_title：Neuroendocrinology

authors： Steger RW,DePaolo L,Asch RH,Silverman AY

更新日期：1983-11-01 00:00:00

abstract：:The role of beta-endorphin in the stimulation of growth hormone secretion elicited by administration of clonidine (Clon), an alpha2-adrenergic agonist, was investigated in awake, freely moving male rats. Animals were infused slowly with either 1 ml of normal rabbit serum (NRS), beta-endorphin antiserum (beta-end-AS) o...

journal_title：Neuroendocrinology

authors： Bruhn TO,Tresco PA,Mueller GP,Jackson IM

更新日期：1989-10-01 00:00:00

abstract：:In order to search for candidate genes related to pituitary adenoma aggressiveness, the present investigation was intended to compare the mRNA expression profile from a pool of four nonfunctional pituitary adenomas (NFPA) with a spinal cord metastasis of a nonfunctional pituitary carcinoma (MNFPC). The metallothionein...

journal_title：Neuroendocrinology

authors： Giorgi RR,Correa-Giannella ML,Casarini AP,Machado MC,Bronstein MD,Cescato VA,Giannella-Neto D

更新日期：2005-01-01 00:00:00

abstract：:Plasma and hypothalamic LHRH was measured by specific radioimmuno-assay in intact and ovariectomized rats, and the values were correlated with peripheral plasma (PP) FSH and LH titers. At most stages of the estrous cycle, plasma LHRH was either undetectable or present at very minimal values. An increase in PP LHRH con...

journal_title：Neuroendocrinology

authors： Wheaton JE,McCann SM

更新日期：1976-01-01 00:00:00

abstract：:Circadian rhythm of blood corticosterone in adrenalectomized rats with (AT rat) or without adrenal autotransplants was investigated. Blood samples were obtained individually at 4-hour intervals for a 24-hour period per week for 5-7 consecutive weeks by the tail tip incision method. Corticosterone responses of the auto...

journal_title：Neuroendocrinology

authors： Murakami N,Takahashi K

更新日期：1982-03-01 00:00:00

abstract：:Oxytocin receptors are regulated during parturition and lactation. Gonadal steroids are thought to be key players in this regulation. It is not well documented how oxytocin receptor gene expression is regulated in the CNS. In this study we analyzed potential estrogen effects on the oxytocin receptor mRNA levels in som...

journal_title：Neuroendocrinology

authors： Quiñones-Jenab V,Jenab S,Ogawa S,Adan RA,Burbach JP,Pfaff DW

更新日期：1997-01-01 00:00:00

abstract：:The present study was undertaken to evaluate the 24-hour periodicity in serum prolactin levels subsequent to transecting the ascending serotonergic system or ablating the suprachiasmatic nuclei (SCN) of adult (185 g) female rats. The ascending serotonergic system was transected at the level of the rostral mesencephalo...

journal_title：Neuroendocrinology

authors： Dunn JD,Johnson DC,Castro AJ,Swenson R

更新日期：1980-08-01 00:00:00

abstract：:The effects of (D-Met2,Pro5)-enkephalinamide--a superactive enkephalin analogue--on the preovulatory discharge of gonadotrophic hormones and on ovulation were investigated. Injection of the opioid (16 nmol) into a lateral cerebral ventricle of regularly cycling female rats immediately before the critical period on the...

journal_title：Neuroendocrinology

authors： Köves K,Marton J,Molnár J,Halász B

更新日期：1981-02-01 00:00:00

abstract：:Dopaminergic agonists are effective in vivo in inhibiting lactotrope proliferation and prolactin (PRL)-secreting pituitary tumors. The purpose of the present study was to demonstrate in vitro actions of dopaminergic agents on proliferation and cell shape of rat lactotropes. Anterior pituitary cells cultured with serum...

journal_title：Neuroendocrinology

authors： Arita J,Hashi A,Hoshi K,Mazawa S,Suzuki S

更新日期：1998-09-01 00:00:00

abstract：:Avian prolactin (PRL) secretion is regulated by vasoactive intestinal peptide (VIP) neurons residing in the infundibular nuclear complex (INF) of the hypothalamus. This VIPergic activity is modulated by stimulatory dopaminergic inputs. Dynorphin, serotonin (5-HT), dopamine (DA) and VIP all appear to stimulate PRL secr...

journal_title：Neuroendocrinology

authors： Youngren O,Chaiseha Y,Al-Zailaie K,Whiting S,Kang SW,El Halawani M

更新日期：2002-03-01 00:00:00

abstract：:The mammalian pineal gland appears to be a major endocrine component in the regulation of photoperiodic responses. The circadian pattern of secretion of the pineal hormone, melatonin, is regulated by the nervous system. Changes in photoperiod, acting via the nervous system, alter the temporal pattern of melatonin secr...

journal_title：Neuroendocrinology

authors： Goldman BD,Darrow JM

更新日期：1983-11-01 00:00:00

abstract：:The neurotransmitter and andrenoceptors involved in the inhibition of luteinizing hormone (LH) release induced by stimulating the locus ceruleus nucleus (LC) have been characterized in ovariectomized, estrogen-primed rats in which the release of LH was triggered by electrical stimulation of the medial preoptic area. B...

journal_title：Neuroendocrinology

authors： Dotti C,Taleisnik S

更新日期：1984-01-01 00:00:00

abstract：:Over the last 10 years, kisspeptins--peptide products of varying lengths encoded by the KISS1 gene--have been found to be key regulators of normal reproductive function throughout life in animals and humans. By activating the kisspeptin receptor [previously known as orphan G protein-coupled receptor 54 (GPR54)], they ...

journal_title：Neuroendocrinology

authors： Prague JK,Dhillo WS

更新日期：2015-01-01 00:00:00

abstract：:Progesterone is readily reduced in humans to its A-ring metabolites, allopregnanolone (3 alpha-hydroxy-5 alpha-pregnan-20-one) and pregnanolone (3 alpha-hydroxy-5 beta-pregnan-20-one). The latter have been reported to have anxiolytic, hypnotic and anesthetic actions when administered to laboratory animals and (or) hum...

journal_title：Neuroendocrinology

authors： Freeman EW,Purdy RH,Coutifaris C,Rickels K,Paul SM

更新日期：1993-10-01 00:00:00

abstract：:The effects of acute stress exposure upon cholecystokinin (CCK) and substance P (SP) concentrations in discrete hypothalamic regions of the adult male rat brain were studied. Animals were exposed to foot shock stress for periods of 2, 4, 10, 30 or 60 min duration; immediately afterwards they were decapitated; brains w...

journal_title：Neuroendocrinology

authors： Siegel RA,Düker EM,Pahnke U,Wuttke W

更新日期：1987-06-01 00:00:00

abstract：:The relationship between concentrations of vasopressin in plasma and cerebrospinal fluid (CSF) was examined under basal and hypoxic conditions in unanesthetized and unrestrained adult female sheep. Under basal conditions mean (+/- SE) concentration of vasopressin (4.1 +/- 0.3 pg/ml) in CSF was significantly (p less th...

journal_title：Neuroendocrinology

authors： Stark RI,Daniel SS,Husain MK,Zubrow AB,James LS

更新日期：1984-06-01 00:00:00

abstract：:Previous work has demonstrated that N-methyl-D-aspartate (NMDA) is capable of stimulating luteinizing hormone release in a variety of species. Interestingly, the ability of NMDA to stimulate luteinizing hormone release is significantly compromised in castrated male and female rats as compared to intact animals. The pu...

journal_title：Neuroendocrinology

authors： Brann DW,Zamorano PL,Chorich LP,Mahesh VB

更新日期：1993-12-01 00:00:00