Surgical treatment of endocrine pancreatic tumours.

abstract：:The hypothalamic GnRH pulse generator activity, which was assessed by the characteristic increases in the multiple unit activity (MUA) specifically associated with the pulsatile LH secretion (MUA volleys), was monitored throughout the estrous cycle of the female goat. Blood samples were collected daily for analysis of...

journal_title：Neuroendocrinology

authors： Tanaka T,Ozawa T,Hoshino K,Mori Y

更新日期：1995-12-01 00:00:00

abstract：:Male Turkish hamsters received horizontal knife cuts within the hypothalamus to investigate the role of afferent and efferent projections of the paraventricular nucleus (PVN) in seasonal regulation of endocrine function. Following surgery, the animals were exposed to either a long (16 h light/8 h dark) or a short (8 h...

journal_title：Neuroendocrinology

authors： Badura LL,Goldman BD

更新日期：1992-04-01 00:00:00

abstract：:In vivo single-unit extracellular recording was used to assess neuronal membrane sensitivity at the level of the midbrain central gray (MCG) to the iontophoresis of luteinizing hormone releasing hormone (LHRH) and beta-endorphin (beta-END). The percentage of change in firing rate was evaluated to determine the effect ...

journal_title：Neuroendocrinology

authors： Schiess MC,Dudley CA,Moss RL

更新日期：1987-06-01 00:00:00

abstract：:Estradiol rapidly regulates the activity of arcuate nucleus (ARH) proopiomelanocortin (POMC) neurons that project to the medial preoptic nucleus (MPN) to regulate lordosis. Orphanin FQ/nociceptin (OFQ/N) acts via opioid receptor-like (ORL)-1 receptors to inhibit these POMC neurons. Therefore, we tested the hypothesis ...

journal_title：Neuroendocrinology

authors： Conde K,Meza C,Kelly MJ,Sinchak K,Wagner EJ

更新日期：2016-01-01 00:00:00

abstract：:TRPM8 is a member of the melastatin-type transient receptor potential ion channel family. Activation by cold or by agonists (menthol, icilin) induces a transient rise in intracellular free calcium concentration ([Ca(2+)](i)). Our previous study demonstrated that Ca(2+)-permeable cation channels play a role in IGF-1-in...

journal_title：Neuroendocrinology

authors： Mergler S,Strowski MZ,Kaiser S,Plath T,Giesecke Y,Neumann M,Hosokawa H,Kobayashi S,Langrehr J,Neuhaus P,Plöckinger U,Wiedenmann B,Grötzinger C

更新日期：2007-01-01 00:00:00

abstract：:The arcuate nucleus-median eminence complex (AM) undergoes major structural and functional changes during normal puberty or if exposed to a pulse of estradiol in the prepuberal period. Those changes are expressed by increased synaptogenesis and by a drastic alteration in the feedback control of anterior pituitary glan...

journal_title：Neuroendocrinology

authors： Rodriguez-Sierra JF,Heydorn WE,Creed GJ,Jacobowitz DM

更新日期：1987-06-01 00:00:00

abstract：:Reliable prediction of disease status is a major challenge in managing gastroenteropancreatic neuroendocrine tumors (GEP-NET). The aim of the study was to validate the NETest®, a blood molecular genomic analysis, for predicting the course of disease in individual patients compared to Chromogranin A (CgA). NETest® (nor...

journal_title：Neuroendocrinology

authors： van Treijen MJC,van der Zee D,Heeres BC,Staal FCR,Vriens MR,Saveur LJ,Verbeek WHM,Korse CM,Maas M,Valk GD,Tesselaar M

更新日期：2020-06-03 00:00:00

abstract：:The storage form of prolactin (PRL) was converted into the releasable form in the lactating rat pituitary gland within 10 min of suckling by 6 pups following 4-5 h of nonsuckling on postpartum day 13-14. The characteristics of the PRL discharge from the releasable pool into the circulation was then studied using a sti...

journal_title：Neuroendocrinology

authors： Grosvenor CE

更新日期：1984-07-01 00:00:00

abstract：:The present study investigates the role of melanotrope proopiomelanocortin-derived peptide in the interrenal stress response to different stressors in male gilthead sea bream, Sparus aurata. Plasma cortisol and acetyl salmon endorphin (acetyl s-EP), as well as pituitary acetyl s-EP contents, were measured during two s...

journal_title：Neuroendocrinology

authors： Mosconi G,Gallinelli A,Polzonetti-Magni AM,Facchinetti F

更新日期：1998-08-01 00:00:00

abstract：:Hypothalamic dopamine (DA) tonically inhibits prolactin (PRL) release from the anterior pituitary gland. Transient escapes from this DA tone elicit a pronounced potentiation of the PRL-releasing action of secretagogues such as thyrotropin-releasing hormone (TRH). Previous evidence has suggested that modulation of Ca(2...

journal_title：Neuroendocrinology

authors： del Mar Hernández M,García Ferreiro RE,García DE,Hernández ME,Clapp C,Martínez de la Escalera G

更新日期：1999-07-01 00:00:00

abstract：:The effects of ovariectomy on the ultrastructure of neurons within the SCH nuclei of the rabbit were investigated. All SCH neurons of the intact controls were similar in that they showed no morphological evidence of enhanced neurosecretory activity. In contrast, two distinct types of neurons were present within the SC...

journal_title：Neuroendocrinology

authors： Clattenburg RE,Montemurro DG,Bruni JE

更新日期：1975-01-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP), a prolactin (PRL)-releasing factor, has been shown to be synthesized within the anterior pituitary. To test the hypothesis that estrogens increase PRL secretion, at least in part, by stimulating VIP secretion, the concentrations of VIP, peptide histidine isoleucine (PHI) and prepro...

journal_title：Neuroendocrinology

authors： Lam KS,Srivastava G,Lechan RM,Lee T,Reichlin S

更新日期：1990-11-01 00:00:00

abstract：:The developmental pattern of hypophyseal luteinizing hormone (LH) during fetal and early postnatal life, and the capacity of fetal and early postnatal pituitaries to synthesize, release and store LH in the absence of any hypothalamic influence were investigated. Pituitary radioimmunoassayable LH was detectable by feta...

journal_title：Neuroendocrinology

authors： Nemeskéri A,Kurcz M,Halász B

更新日期：1984-05-01 00:00:00

abstract：:Central or systemic administration of morphine disrupts maternal behavior in steroid-primed, pup-induced virgin and lactating rats. Morphine, the prototypical mu agonist, also interacts with different opioid receptor subtypes. The present study examined the effectiveness of five receptor-selective agonists, in additio...

journal_title：Neuroendocrinology

authors： Mann PE,Kinsley CH,Bridges RS

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND/AIMS:Both prostaglandin E2 (PGE2) and estradiol stimulate fetal ACTH secretion and augment fetal ACTH responses to stress. We have reported that estradiol increases prostaglandin endoperoxide synthase-2 (PGHS-2), and we have proposed that there is a positive feedback relationship between estrogen and fetal h...

journal_title：Neuroendocrinology

authors： Schaub CE,Keller-Wood M,Wood CE

更新日期：2008-01-01 00:00:00

abstract：:Previous work has demonstrated that physiological concentrations of 17beta-estradiol can protect the female rat brain against middle cerebral artery occlusion (MCAO)-induced ischemic damage. The present study examined whether therapeutic doses of the clinically relevant selective estrogen receptor modulator (SERM), ta...

journal_title：Neuroendocrinology

authors： Mehta SH,Dhandapani KM,De Sevilla LM,Webb RC,Mahesh VB,Brann DW

更新日期：2003-01-01 00:00:00

abstract：:Dopaminergic agonists are effective in vivo in inhibiting lactotrope proliferation and prolactin (PRL)-secreting pituitary tumors. The purpose of the present study was to demonstrate in vitro actions of dopaminergic agents on proliferation and cell shape of rat lactotropes. Anterior pituitary cells cultured with serum...

journal_title：Neuroendocrinology

authors： Arita J,Hashi A,Hoshi K,Mazawa S,Suzuki S

更新日期：1998-09-01 00:00:00

abstract：:We have examined the spinal cord for the presence of glucocorticoid-binding sites. For this purpose, cytosol from the spinal cord of adrenalectomized rats was incubated with (3H)-dexamethasone. Maximal binding was obtained after 20 h of incubation at 0 degree C in the presence of 20 mM molybdate, whereas at 20 degrees...

journal_title：Neuroendocrinology

authors： Orti E,Coirini H,De Nicola AF

更新日期：1985-03-01 00:00:00

abstract：:Experiments were carried out to increase the endogenous levels of TRH in brain and spinal cord. After 7 days of continuous oral ingestion of TRH analogs (D-pGlu-Leu-ProNH2, pGlu-Leu-Pro, pGlu-Pro-ProNH2, or pGlu-Leu-pyrrolidide), spinal cord and brain levels of TRH were elevated, whereas the content of TRH metabolite,...

journal_title：Neuroendocrinology

authors： Prasad C,Eloby-Childress S,Iriuchijima T,Wilber JF,Szirtes T,Kisfaludy L

更新日期：1989-02-01 00:00:00

abstract：UNLABELLED:Opioid peptides are present in both the posterior pituitary (PP) and stalk-median eminence (SME). Their effects on the dopaminergic neurons in the SME are well documented, but little is known concerning their role in the regulation of dopamine (DA) release from the PP. The objectives of this study were (1) t...

journal_title：Neuroendocrinology

authors： Garris PA,Ben-Jonathan N

更新日期：1990-10-01 00:00:00

abstract：:The hypothalamic neurons containing substance P (SP) were examined immunohistochemically in rats with a normal estrous cycle or persistent estrus (PE), in pregnancy and in lactating state. In PE animals, the neurons increased in number 1 week after ovariectomy, but then decreased and disappeared. During pregnancy, the...

journal_title：Neuroendocrinology

authors： Tsuruo Y,Hisano S,Nakanishi J,Katoh S,Daikoku S

更新日期：1987-05-01 00:00:00

abstract：:The presence and distribution of bombesin (BBS)/gastrin-releasing peptide (GRP)-like immunoreactivity (IR) was examined in the goldfish pituitary and forebrain. BBS/GRP-like IR nerve fibres were consistently observed throughout the pituitary neurointermediate lobe (NIL); occasionally, BBS/GRP-like material was localiz...

journal_title：Neuroendocrinology

authors： Himick BA,Peter RE

更新日期：1995-04-01 00:00:00

abstract：:It is now well documented that various polyclonal antisera to the human growth hormone-releasing factor (hGHRF, somatocrinin) visualize in the brain by immunohistochemistry the classical hypothalamic hypophysiotropic neurons and also antigens present in otherwise characterized peptidergic neuronal systems. The nature ...

journal_title：Neuroendocrinology

authors： Ciofi P,Tramu G,Bloch B

更新日期：1990-04-01 00:00:00

abstract：:Substance P (SP) is known to act on pituitary hormone release either at the hypothalamic level or directly at the pituitary level. In order to investigate whether SP is present in the pituitary gland and to localize the peptide at the cellular and subcellular levels, the immunocytological method was used. Rat pituitar...

journal_title：Neuroendocrinology

authors： Morel G,Chayvialle JA,Kerdelhue B,Dubois PM

更新日期：1982-01-01 00:00:00

abstract：:The reuptake of dopamine into nerve terminals is the primary mechanism of inactivation of this neurotransmitter in the synaptic cleft. We report sex differences and estrous cycle variations of rat striatal dopamine uptake sites. During the estrous cycle, peak density of striatal dopamine uptake sites labelled with [3H...

journal_title：Neuroendocrinology

authors： Morissette M,Di Paolo T

更新日期：1993-07-01 00:00:00

abstract：:The hypothesis was tested that corticotropin-releasing factor (CRF) is involved in the inhibition of gonadotropin secretion during chronic hyperprolactinemia. Two models of hyperprolactinemia were used, namely inoculation with the prolactin (PRL)-secreting tumor 7315b and implantation of isogenic pituitary glands. Gon...

journal_title：Neuroendocrinology

authors： Kooy A,de Greef WJ,Vreeburg JT,Hackeng WH,Ooms MP,Lamberts SW,Weber RF

更新日期：1990-03-01 00:00:00

abstract：:Immunoneutralization of endogenous gonadal steroids has recently been shown to modify pineal beta-adrenoceptor function in intact Merino ewes. In the current study, interactions between gonadal steroids and these receptors have been further investigated. beta-Adrenoceptor density and binding affinity both showed time-...

journal_title：Neuroendocrinology

authors： Foldes A,Maxwell CA,Scaramuzzi RJ,Donnelly JB,Hoskinson RM,Rintoul AJ

更新日期：1985-12-01 00:00:00

abstract：:Rats bearing transplanted prolactin-secreting tumors are known to have very high prolactin levels in the serum, reduced hypothalamic opiate concentrations, increasing hypothalamic dopamine synthesis and increased hypophyseal portal blood dopamine levels. Further, it has been shown that incubation in 3H-leucine of ante...

journal_title：Neuroendocrinology

authors： Login IS,Nagy I,MacLeod RM

更新日期：1981-08-01 00:00:00

abstract：:Tyrosine hydroxylase activity in noradrenergic neurons of the locus coeruleus was found to rise in bilaterally adrenalectomized adult mice, with maximum increase of the enzyme activity (52% above control) occurring 7 days after the surgery. No such increase of tyrosine hydroxylase activity was found in dopaminergic ne...

journal_title：Neuroendocrinology

authors： Markey KA,Sze PY

更新日期：1984-04-01 00:00:00

abstract：:The effect of steroids on the two gonadotropin-releasing hormone (GnRH) forms present in the eel (mammalian GnRH, mGnRH and chicken GnRH-II, cGnRH-II), as well as on gonadotropin (GTH), was studied using specific radioimmunoassays. Female silver eels received chronic treatments with various steroids (estradiol, testos...

journal_title：Neuroendocrinology

authors： Montero M,Le Belle N,King JA,Millar RP,Dufour S

更新日期：1995-05-01 00:00:00