Pathophysiological effect of hepatic ischemia and reperfusion after hepatectomy in dogs with obstructive jaundice, focusing on the effect of coenzyme Q10 and styrene-co-maleic acid superoxide dismutase.

abstract：:We report a 13-year-old girl who presented with hepatic failure and hemolytic anemia. Laboratory findings showed a normal serum copper level (104 microg/dl), high urinary copper level (2370 microg/dl), and low serum ceruloplasmin level (14.3 microg/dl). Slit-lamp examination revealed Kayser-Fleischer rings on her corn...

journal_title：Journal of gastroenterology

authors： Sakaida I,Kawaguchi K,Kimura T,Tamura F,Okita K

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Gene therapy is a promising therapeutic method but is severely hampered due to its lack of an ideal delivery system. Therefore, in this study, a nonviral and magnetic resonance imaging (MRI) visible vector, polyethylene glycol-grafted polyethylenimine and superparamagnetic iron oxide nanoparticles (PEG-g-PEI...

journal_title：Journal of gastroenterology

authors： Chen Y,Lian G,Liao C,Wang W,Zeng L,Qian C,Huang K,Shuai X

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The endoscopic abnormalities present in the small bowel (SB) of patients with portal hypertension (PH) are not well understood. This study sought to evaluate endoscopic findings of the SB in patients with PH by double balloon endoscopy (DBE). METHODS:We evaluated the endoscopic findings of SB in 15 patients...

journal_title：Journal of gastroenterology

authors： Kodama M,Uto H,Numata M,Hori T,Murayama T,Sasaki F,Tsubouchi N,Ido A,Shimoda K,Tsubouchi H

更新日期：2008-01-01 00:00:00

abstract：:Cyclin D1 overexpression is remarkably frequent in several human carcinomas and is believed to be a critical event in oncogenesis. We examined cyclin D1 expression, p53 expression, and the Ki-67 labeling index by immunostaining in human gallbladder mucosa in conditions varying from normal to malignant tissue. We also ...

journal_title：Journal of gastroenterology

authors： Itoi T,Shinohara Y,Takeda K,Nakamura K,Takei K,Sanada J,Horibe T,Saito T,Kasuya K,Ebihara Y

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:It remains unknown whether Kupffer-phase images in Sonazoid-enhanced ultrasonography (US) can be used to predict hypervascularization of borderline lesions. Therefore, we aimed to clarify whether Kupffer-phase images in Sonazoid-enhanced ultrasonography can predict subsequent hypervascularization in hypovasc...

journal_title：Journal of gastroenterology

authors： Inoue T,Hyodo T,Korenaga K,Murakami T,Imai Y,Higaki A,Suda T,Takano T,Miyoshi K,Koda M,Tanaka H,Iijima H,Ochi H,Hirooka M,Numata K,Kudo M

更新日期：2016-02-01 00:00:00

abstract：:We reviewed articles on the epidemiology and clinical characteristics of gastroesophageal reflux disease (GERD) in Japan to clarify these features of GERD in this country. Although the definition of GERD depends on the individual study, the prevalence of GERD has been increasing since the end of the 1990s. The reasons...

journal_title：Journal of gastroenterology

authors： Fujiwara Y,Arakawa T

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Endoscopic sphincterotomy (ES) is widely performed in patients with common bile duct stones (CBDS). However, the long-term outcomes of patients following ES have not been sufficiently elucidated. Impaired papillary function following ES may result in additional late complications. In contrast, endoscopic pap...

journal_title：Journal of gastroenterology

authors： Doi S,Yasuda I,Mukai T,Iwashita T,Uemura S,Yamauchi T,Nakashima M,Adachi S,Shimizu M,Tomita E,Itoi T,Moriwaki H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:There have been few reports on hepatocellular carcinoma (HCC) in nonalcoholic steatohepatitis (NASH) and the natural history of NASH. Accordingly, we assessed the clinical features of HCC in NASH, the risk factors for HCC, and natural history of NASH with advanced fibrosis. PATIENTS AND METHODS:There were 3...

journal_title：Journal of gastroenterology

authors： Hashimoto E,Yatsuji S,Tobari M,Taniai M,Torii N,Tokushige K,Shiratori K

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Autoimmune pancreatitis (AIP) is considered to be a pancreatic lesion of IgG4-related systemic disease, but about 20% of AIP patients do not have elevated serum IgG4 levels. This study aimed to clarify the pathophysiology of AIP patients without elevated serum IgG4 levels. METHODS:Fifty-eight AIP patients w...

journal_title：Journal of gastroenterology

authors： Kamisawa T,Takuma K,Tabata T,Inaba Y,Egawa N,Tsuruta K,Hishima T,Sasaki T,Itoi T

更新日期：2011-01-01 00:00:00

abstract：:We estimated the levels of free sialic acid and sialylated oligosaccharides excreted in the urine of normal donors (n = 10) and patients with gastric cancer (n = 6) and colorectal cancer (n = 4). The total sialic acid level in cancer patients was similar to that in normal donors. However, the ratios of glycosidically ...

journal_title：Journal of gastroenterology

authors： Shimada I,Shoji M,Futatsuya R,Katoh T,Kominato Y,Sakamoto T,Fujikura T

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:The model for end-stage liver disease (MELD) is useful for assessing the recipients of liver transplants, namely, deceased-donor transplantation. The application of MELD for living donor liver transplantation (LDLT) is under investigation. Thus, the aim of this study was to analyze the impact of the MELD sco...

journal_title：Journal of gastroenterology

authors： Kogure T,Ueno Y,Kawagishi N,Kanno N,Yamagiwa Y,Fukushima K,Satomi S,Shimosegawa T

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Angiogenesis is essential for gastric ulcer healing. Recent results suggest that vascular endothelial growth factor receptor 1 (VEGFR1), which binds to VEGF, promotes angiogenesis. In the present study, we investigated the role of VEGFR1 signaling in gastric ulcer healing and angiogenesis. METHODS:Gastric u...

journal_title：Journal of gastroenterology

authors： Sato T,Amano H,Ito Y,Eshima K,Minamino T,Ae T,Katada C,Ohno T,Hosono K,Suzuki T,Shibuya M,Koizumi W,Majima M

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Subunit A of coagulation factor XIII (FXIII-A) is important for clot stability and acts in the subsequent wound healing process. Loss of plasma FXIII-A has been reported after surgery, sepsis, and inflammatory conditions. In the intestinal mucosa, FXIII-A is expressed by macrophages and cellular FXIII-A has ...

journal_title：Journal of gastroenterology

authors： Soendergaard C,Kvist PH,Seidelin JB,Pelzer H,Nielsen OH

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Infection with Helicobacter pylori has been associated with chronic idiopathic urticaria (CIU). The aim of this study was to investigate the efficacy of H. pylori eradication in the treatment of patients with CIU. METHODS:Fifty patients with CIU (16 men and 34 women; age 25-75 years) and 100 sex- and age-ma...

journal_title：Journal of gastroenterology

authors： Fukuda S,Shimoyama T,Umegaki N,Mikami T,Nakano H,Munakata A

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The risk for lymph node metastasis and the prognostic significance of pedunculated-type T1 colorectal carcinomas (CRCs) require further study. We aimed to assess the validity of the 2014 Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines based on long-term outcomes of pedunculated-type T1...

journal_title：Journal of gastroenterology

authors： Asayama N,Oka S,Tanaka S,Nagata S,Furudoi A,Kuwai T,Onogawa S,Tamura T,Kanao H,Hiraga Y,Okanobu H,Kuwabara T,Kunihiro M,Mukai S,Goto E,Shimamoto F,Chayama K

更新日期：2016-07-01 00:00:00

abstract：:Progressive familial intrahepatic cholestasis (PFIC) syndromes are characterized by defects in transporters of conjugated bile acids into the bile canaliculus. Three genes (ATP8B1, ABCB11, ABCB4) are associated with the different forms, but no easy genotype-phenotype correlations help in the prioritization for gene te...

journal_title：Journal of gastroenterology

authors： Nobili V,Di Giandomenico S,Francalanci P,Callea F,Marcellini M,Santorelli FM

更新日期：2006-06-01 00:00:00

abstract：:A rare case of benign diaphragmatic schwannoma in a 38-year-old female is reported. Precontrast computed tomography (CT) showed an encapsulated well-defined round homogeneous tumor with central calcification, measuring approximately 5 cm in diameter, arising from the left diaphragm. Contrast-enhanced CT and gadolinium...

journal_title：Journal of gastroenterology

authors： Koyama S,Araki M,Suzuki K,Fukutomi H,Maruyama T,Mun Y,Otsuka M,Fukao K

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Neovascularization was shown to be critically involved in the progression of multiple cancers, and treatment approaches targeting tumor-associated neovascularization provide convincing results in recent years in some tumor entities. However, little is known about the tumor-associated neovascularization in hi...

journal_title：Journal of gastroenterology

authors： Thelen A,Scholz A,Benckert C,Schröder M,Weichert W,Wiedenmann B,Neuhaus P,Jonas S

更新日期：2008-01-01 00:00:00

abstract：:Human glucagonoma cells were isolated and maintained in vitro. Incubation experiments showed that carbachol (Cch) induced the simultaneous release of glucagon, VIP (vasoactive intestinal polypeptide), and pancreatic polypeptide (PP) at levels significantly higher than basal levels. Atropine abolished the stimulatory e...

journal_title：Journal of gastroenterology

authors： Funakoshi A,Yasunami Y,Ryu S,Shinozaki H,Jimi A,Ikeda S

更新日期：1994-12-01 00:00:00

abstract：:Two hundred and three patients with Crohn's disease seen at Kyushu University, Fukuoka University, and their affiliated centers from 1973 to 1988 were followed for 4.4 +/- 3.2 years (mean +/- SD), to evaluate the prognosis relative to life span and surgery. Cumulative survival rate and cumulative operation rate were c...

journal_title：Journal of gastroenterology

authors： Iida M,Yao T,Okada M

更新日期：1995-11-01 00:00:00

abstract：:We investigated the therapeutic effects of egualen sodium (KT1-32), a new antiulcer agent, on chronic erosive and atrophic gastritis induced by 5 months' administration of sodium taurocholate (TCA; 5 mM) in rats. The chronic gastritis was manifested by mucosal surface injuries (erosions), reduced mucosal thickness, re...

journal_title：Journal of gastroenterology

authors： Mochizuki S,Matsumoto M,Wakabayashi S,Kosakai K,Tomiyama A,Kishimoto S

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Few studies have investigated measures to prevent small bowel injuries induced by aspirin. Our aim was to evaluate the effect of probiotic treatment on the small bowel injuries induced by chronic low-dose aspirin use. METHODS:Thirty-five patients who took low-dose enteric-coated aspirin 100 mg daily (for mo...

journal_title：Journal of gastroenterology

authors： Endo H,Higurashi T,Hosono K,Sakai E,Sekino Y,Iida H,Sakamoto Y,Koide T,Takahashi H,Yoneda M,Tokoro C,Inamori M,Abe Y,Nakajima A

更新日期：2011-07-01 00:00:00

abstract：:The 13C-urea breath test (13C-UBT) is a non-invasive method for detecting Helicobacter pylori. This study was performed to determine the cutoff value and evaluate the sensitivity and specificity of 13C-UBT in Taiwan. 13C-Urea (100 mg of 99% 13C-labeled urea) was dissolved in 50 ml sterile water for the test. The test ...

journal_title：Journal of gastroenterology

authors： Wang WM,Lee SC,Ding HJ,Jan CM,Chen LT,Wu DC,Liu CS,Peng CF,Chen YW,Huang YF,Chen CY

更新日期：1998-06-01 00:00:00

abstract：:We report a 66-year-old man with hepatocellular carcinoma who was positive for hepatitis B surface antigen, and was hospitalized because of hypoglycemia and hypertension. His plasma renin activity was normal (2.3 ng/ml per h), but concentrations of angiotensin I (>2500 pg/ml) and II (86 pg/ml) were high. Increased ang...

journal_title：Journal of gastroenterology

authors： Arai H,Saitoh S,Matsumoto T,Makita F,Mitsugi S,Yuasa K,Takagi H,Mori M

更新日期：1999-08-01 00:00:00

abstract：:Fulminant hepatic failure (FHF) usually has a fatal prognosis without liver transplantation. We describe the case of a woman who developed FHF, and was evaluated as a candidate for liver transplantation, but who was cured without transplantation through intensive medical care that included glucagon-insulin therapy, me...

journal_title：Journal of gastroenterology

authors： Masuhara M,Yagawa T,Aoyagi M,Suzuki C,Sakaguchi E,Segawa M,Hironaka K,Kayano K,Tamura F,Seguchi M,Soejima Y,Murakami F,Sakaida I,Tateishi A,Fukumoto Y,Okita K

更新日期：2001-05-01 00:00:00

abstract：:There is an abundance of evidence that nitric oxide plays a critical role in regulating several components of gastrointestinal mucosal defense. Suppression of nitric oxide synthesis increases susceptibility to injury, while administration of nitric oxide donors increases resistance to injury. On the other hand, nitric...

journal_title：Journal of gastroenterology

authors： Elliott SN,Wallace JL

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:It is suggested that nonalcoholic fatty liver disease (NAFLD), including nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH), can be associated with insomnia and gastro-esophageal reflux disease (GERD). The relationship between GERD and insomnia in subjects with biopsy-proven NAFLD was in...

journal_title：Journal of gastroenterology

authors： Taketani H,Sumida Y,Tanaka S,Imajo K,Yoneda M,Hyogo H,Ono M,Fujii H,Eguchi Y,Kanemasa K,Chayama K,Itoh Y,Yoshikawa T,Saibara T,Fujimoto K,Nakajima A,Japan Study Group of NAFLD.

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:Single nucleotide polymorphisms (SNPs) of the adiponectin gene have been reported to be associated with insulin resistance and the prevalence of type-2 diabetes. We investigated the SNPs of adiponectin in non-alcoholic fatty liver disease (NAFLD) patients. METHODS:One hundred nineteen patients histologically d...

journal_title：Journal of gastroenterology

authors： Tokushige K,Hashimoto E,Noto H,Yatsuji S,Taniai M,Torii N,Shiratori K

更新日期：2009-01-01 00:00:00

abstract：:In this study, we quantitatively measured glycogen levels in tissue samples obtained from tumors, regions adjacent to tumor, and regions of normal colorectum to determine whether the levels were related to cell cycle and cancer growth. Glycogen levels were analyzed in relation to histopathological factors, (tumor size...

journal_title：Journal of gastroenterology

authors： Takahashi S,Satomi A,Yano K,Kawase H,Tanimizu T,Tuji Y,Murakami S,Hirayama R

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Peristaltic reflex does not fully explain the polarity of peristalsis. In the distal colon, we propose that the balance of circular muscle contraction proximal and distal to the pellet is a local reflex that predicts polarity of peristalsis. METHODS:Guinea pig distal colon segments were harvested, and fecal...

journal_title：Journal of gastroenterology

authors： Gribovskaja-Rupp I,Kwak JM,Takahashi T,Ludwig K

更新日期：2014-05-01 00:00:00