HBV-related fulminant hepatic failure: successful intensive medical therapy in a candidate for liver transplantation.

abstract：:The incidence and prevalence of primary biliary cirrhosis show wide geographic differences. The frequency of this disease in Japan is lower than in Northern Europe. To elucidate the immunoreactivity of serum with enzymes of the 2-oxo-acid dehydrogenase complex (2-OADC) and the M2 mitochondrial antigenic complex in Jap...

journal_title：Journal of gastroenterology

authors： Omagari K,Rowley MJ,Jois JA,Feeney SJ,Komatsu K,Maeda T,Onishi S,Yamazaki K,Suzuki K,Galperin C,Mackay IR

更新日期：1996-02-01 00:00:00

abstract：:In 1992, a seroepidemiologic study was carried out among hemodialysis patients and the general population in Fukuoka and Okinawa, Japan to determine the presence of hepatitis C virus (HCV) infection and HCV viremia. The markers used were antibody to HCV, determined by second-generation assay (anti-HCV), and HCV RNA, d...

journal_title：Journal of gastroenterology

authors： Hayashi J,Yoshimura E,Nabeshima A,Kishihara Y,Ikematsu H,Hirata M,Maeda Y,Kashiwagi S

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Cold snare polypectomy (CSP) has not undergone sufficient histopathological evaluation. This study aimed to clarify the histopathological features of CSP specimens, including resection depth and layer, as compared with endoscopic mucosal resection (EMR). METHODS:Polyps were recruited retrospectively. Sessil...

journal_title：Journal of gastroenterology

authors： Ito A,Suga T,Ota H,Tateiwa N,Matsumoto A,Tanaka E

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:There are substantial differences in inflammatory bowel disease (IBD) genetics depending on the populations examined. We aimed to identify Japanese population-specific or true culprit susceptibility genes through a meta-analysis of past genetic studies of Japanese IBD. METHODS:For this study, we reviewed 2,...

journal_title：Journal of gastroenterology

authors： Arimura Y,Isshiki H,Onodera K,Nagaishi K,Yamashita K,Sonoda T,Matsumoto T,Takahashi A,Takazoe M,Yamazaki K,Kubo M,Fujimiya M,Imai K,Shinomura Y

更新日期：2014-08-01 00:00:00

abstract：:The aim of this study was to examine the diurnal variations in ornithine decarboxylase (ODC) activity and apoptosis in the small intestinal mucosa of Mongolian gerbils. First, the feeding, drinking, and ambulatory patterns of the gerbils were recorded. The results indicated that Mongolian gerbils lost diurnal cyclicit...

journal_title：Journal of gastroenterology

authors： Kashiwagi Y,Fujimoto K,Iwakiri R,Yoshida T,Noda T,Aw TY,Niho Y,Sakata T

更新日期：2000-01-01 00:00:00

abstract：:To investigate the role played by cytokines in chronic pancreatitis, we examined serum levels of interleukin-1 beta (IL-1 beta) and interleukin-6 (IL-6) by radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) in 33 patients with definitively diagnosed chronic pancreatitis. All the patients, who had rec...

journal_title：Journal of gastroenterology

authors： Bamba T,Yoshioka U,Inoue H,Iwasaki Y,Hosoda S

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:In acute pancreatitis, pancreatic phospholipase A(2) (PLA2) in the circulating blood hydrolyzes phospholipids contained in plasma lipoproteins, liberating eicosanoid precursors that are subsequently converted to various eicosanoids. The pathophysiological significance of eicosanoid synthesis via this pathway...

journal_title：Journal of gastroenterology

authors： Motoyoshi M,Sugiyama M,Atomi Y,Kimura W,Nagawa H

更新日期：2006-11-01 00:00:00

abstract：:We report a case of Cruveihier-Baumgarten syndrome associated with portal vein thrombosis that developed, slowly during a 2-year period after endoscopic variceal sclerotherapy. The thrombosis led to the disappearance of the venous hum and the dilated abdominal wall veins characteristic of this syndrome. A 73-year-old ...

journal_title：Journal of gastroenterology

authors： Yamakawa O,Ohta H,Watanabe H,Motoo Y,Okai T,Kadoya M,Matsui O,Sawabu N

更新日期：1996-08-01 00:00:00

abstract：:The effect of nifedipine administration (10 mg) on esophageal acid exposure time was investigated in 11 non-reflux esophagitis (non-RE) patients and 11 grade C (Los Angeles classification) reflux esophagitis (RE) patients. In each subject, esophageal pH monitoring was performed, with the subject in the supine position...

journal_title：Journal of gastroenterology

authors： Ishikawa H,Iwakiri K,Sugiura T,Kobayashi M

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:LYVE-1, a specific marker of lymphatics, is expressed in hepatic sinusoidal endothelium. A previous study revealed that LYVE-1 expression in sinusoidal endothelium was reduced in cirrhosis. However, it is still obscure how LYVE-1 expression in sinusoidal endothelium was reduced during the disease progression...

journal_title：Journal of gastroenterology

authors： Arimoto J,Ikura Y,Suekane T,Nakagawa M,Kitabayashi C,Iwasa Y,Sugioka K,Naruko T,Arakawa T,Ueda M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:A new capsule endoscope has been developed by Olympus Medical Systems. The visualization and usefulness of its real-time image viewer for gastric transit abnormality were evaluated by using this new device. METHODS:Thirty-seven consecutive patients were enrolled. In cases of gastric transit abnormality (gas...

journal_title：Journal of gastroenterology

authors： Ogata H,Kumai K,Imaeda H,Aiura K,Hisamatsu T,Okamoto S,Iwao Y,Sugino Y,Kitajima M,Hibi T

更新日期：2008-01-01 00:00:00

abstract：:Several components of the gastrointestinal tract including the esophagogastric junction (EGJ) show circumferential asymmetry in the formation of pathological lesions, which is caused by the morphological and functional asymmetry of the gastrointestinal tract. Pressure in the lower esophageal sphincter (LES) is higher ...

journal_title：Journal of gastroenterology

authors： Kinoshita Y,Furuta K,Adachi K,Amano Y

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Autoimmune pancreatitis (AIP) is a unique form of pancreatitis and can be complicated with various extrapancreatic lesions. Little is known about the long-term clinical course of AIP. Here we aimed to document the clinical course of AIP. METHODS:For this study, we recruited 21 patients, averaging 66.5 years in...

journal_title：Journal of gastroenterology

authors： Uchida K,Yazumi S,Nishio A,Kusuda T,Koyabu M,Fukata M,Miyoshi H,Sakaguchi Y,Fukui T,Matsushita M,Takaoka M,Okazaki K

更新日期：2009-01-01 00:00:00

abstract：:A 65-year-old woman was admitted to our hospital with the diagnosis of gallbladder tumor. Right extended hepatic lobectomy plus lymph node dissection of the hepatoduodenal ligament and left hepaticojejunostomy with Roux-en-Y reconstruction was performed in July, 1993. The gallbladder tumor was histologically proven to...

journal_title：Journal of gastroenterology

authors： Suganuma M,Marugami Y,Sakurai Y,Ochiai M,Hasegawa S,Imazu H,Matsubara T,Funabiki T,Kuroda M

更新日期：1997-12-01 00:00:00

abstract：:In this study, we used magnetic resonance (MR) imaging to measure portal blood flow in 12 healthy controls and 17 cirrhotics while they were breath-holding after inspiration and after expiration. We then compared the results with measurements made during normal respiration in the healthy controls and cirrhotics. Blood...

journal_title：Journal of gastroenterology

authors： Sugano S,Yamamoto K,Sasao K,Watanabe M

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Previous studies investigating the impact of tumor location on colorectal cancer prognosis only compared two groups by location, e.g., 'right-sided colon vs. left-sided colon,' 'colon vs. rectum,' and 'right-sided (right-sided colon) vs. left-sided (left-sided colon and rectum).' This nationwide multicenter ...

journal_title：Journal of gastroenterology

authors： Shida D,Inoue M,Tanabe T,Moritani K,Tsukamoto S,Yamauchi S,Sugihara K,Kanemitsu Y

更新日期：2020-10-01 00:00:00

abstract：:We present herein a case of a 75-year-old Japanese man who had developed a pancreatic abscess 7 years after a longitudinal pancreatojejunostomy for chronic pancreatitis. The patient, a heavy drinker of alcohol, underwent surgical decompression of a ductal obstruction to relieve persistent abdominal pain due to severel...

journal_title：Journal of gastroenterology

authors： Suzuki A,Matsunaga T,Aoki S,Hirayama T,Nakagawa N,Shibata K,Yabana T,Kawasaki H,Takasaka H,Sasaki K,Katsuramaki T,Mukaiya M,Hirata K,Imai K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The clinicopathologic features of cystic neoplasms of the liver, such as cystadenoma and cystadenocarcinoma, are poorly defined because these lesions are extremely rare. METHODS:Clinicopathologic findings in six patients who underwent surgery for a cystic hepatic neoplasm were reviewed retrospectively to de...

journal_title：Journal of gastroenterology

authors： Hai S,Hirohashi K,Uenishi T,Yamamoto T,Shuto T,Tanaka H,Kubo S,Tanaka S,Kinoshita H

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Several findings suggest that eosinophilic esophagitis (EoE) is strongly associated with atopy and allergen-driven, Th2-type immune responses, indicating the association of EoE with immune dysregulation. The objective of this study is to ascertain the molecular mechanism involved in EoE disease development a...

journal_title：Journal of gastroenterology

authors： Zafra MP,Cancelliere N,Rodríguez del Río P,Ruiz-García M,Estévez L,Andregnette V,Sánchez-García S,Fiandor A,Collantes E,Sastre J,Quirce S,Ibáñez MD,del Pozo V

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Fulminant non-A, non-B, non-C hepatitis has a high mortality rate, making the identification of its causative agent imperative. Cytomegalovirus, Epstein-Barr virus, human herpesvirus-6, and herpes simplex virus are all members of the herpesviridae family that are associated with fatal hepatic failure. We inv...

journal_title：Journal of gastroenterology

authors： Ishikawa K,Hasegawa K,Naritomi T,Kanai N,Ogawa M,Kato Y,Kobayashi M,Torii N,Hayashi N

更新日期：2002-01-01 00:00:00

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine produced by a wide variety of lymphoid and non-lymphoid tissues. We studied the relationship between IL-6 and the liver in an attempt to elucidate this cytokine's role in hepatitis C-induced liver inflammation. We investigated the behavior of serum IL-6 in 25 patients wit...

journal_title：Journal of gastroenterology

authors： Malaguarnera M,Di Fazio I,Romeo MA,Restuccia S,Laurino A,Trovato BA

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Dual oral therapy with daclatasvir plus asunaprevir yielded an SVR rate of 85% among patients with genotype 1b HCV. Treatment failure mainly occurred in patients with pre-existing HCV with NS5A-Y93H mutation. The significance of the mutation was evaluated. METHODS:The percent of serum NS5A-Y93H strains rela...

journal_title：Journal of gastroenterology

authors： Uchida Y,Kouyama J,Naiki K,Sugawara K,Ando S,Nakao M,Motoya D,Inao M,Imai Y,Nakayama N,Mochida S

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:We recently reported that the presence of a papillary adenocarcinoma (pap) component was an independent risk factor for lymphatic involvement in endoscopically resected early gastric cancer (EGC). This study aimed to investigate the potential association between the presence of a pap component in EGC and lym...

journal_title：Journal of gastroenterology

authors： Sekiguchi M,Kushima R,Oda I,Suzuki H,Taniguchi H,Sekine S,Fukagawa T,Katai H

更新日期：2015-04-01 00:00:00

abstract：:Using commercial quantitative assays, quantitative hepatitis B surface antigen (qHBsAg) has improved our understanding and management of chronic hepatitis B (CHB). The HBsAg level is highest in the immune tolerance phase, starts to decline during the immune clearance phase, and decreases slowly but progressively after...

journal_title：Journal of gastroenterology

authors： Tseng TC,Kao JH

更新日期：2013-01-01 00:00:00

abstract：:Because most gastric cancers develop from a background of Helicobacter pylori-infected gastric mucosa, H. pylori plays an important role in gastric carcinogenesis. Therefore, eradication of H. pylori may inhibit the incidence of gastric cancers. In experimental studies, H. pylori eradication has proved to act as a pro...

journal_title：Journal of gastroenterology

authors： Kato M,Asaka M,Ono S,Nakagawa M,Nakagawa S,Shimizu Y,Chuma M,Kawakami H,Komatsu Y,Hige S,Takeda H

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Percutaneous microwave ablation and radiofrequency ablation are two commonly used modalities for the treatment of hepatocellular carcinoma; however, comparisons of them have not been documented adequately. METHODS:Of 102 patients with biopsy-proved hepatocellular carcinoma, 49 (98 nodules) were treated perc...

journal_title：Journal of gastroenterology

authors： Lu MD,Xu HX,Xie XY,Yin XY,Chen JW,Kuang M,Xu ZF,Liu GJ,Zheng YL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Several small, prospective, open studies suggest that leukocytapheresis might be efficient in patients with steroid-dependent ulcerative colitis (UC). AIM:To evaluate the short- and long-term effectiveness of leukocytapheresis for the management of steroid-dependent UC in clinical practice. METHODS:A Web-b...

journal_title：Journal of gastroenterology

authors： Cabriada JL,Domènech E,Ibargoyen N,Hernández V,Clofent J,Ginard D,Gutiérrez-Ibarluzea I,Hinojosa J

更新日期：2012-04-01 00:00:00

abstract：:The proliferative activity of serrated adenomas of the large intestine was determined by examining proliferating cell nuclear antigen (PCNA). The PCNA labeling index, determined by visual inspection, and the PCNA area rate, determined with the newly developed image processor for analytical pathology (IPAP), of serrate...

journal_title：Journal of gastroenterology

authors： Fujishima N

更新日期：1996-04-01 00:00:00

abstract：:CYFRA 21-1 is a fragment of cytokeratin 19 (CK 19). Four patients with large intrahepatic (or peripheral) cholangiocarcinoma (CC) and high serum levels of CYFRA 21-1 (normal, < or = 2 ng/ml) are reported. CYFRA 21-1 levels exceeded 9 ng/ml in all 4 patients. Carcinoembryonic antigen (CEA), was high in 1 (CEA; normal r...

journal_title：Journal of gastroenterology

authors： Kashihara T,Ohki A,Kobayashi T,Sato T,Nishizawa H,Ogawa K,Tako H,Kawakami F,Tsuji M,Tamaoka K

更新日期：1998-06-01 00:00:00

abstract：:Small bowel transit time (SBTT) in 15 young and 13 elderly women was assessed by measuring breath hydrogen concentrations after they had consumed a solid test meal. The meal consisted of 200 g cooked rice, 50 ml miso (made from fermented soy bean curd) soup, a boiled egg, and 95.5 g of cooked soy beans with mixed vege...

journal_title：Journal of gastroenterology

authors： Kagaya M,Iwata N,Toda Y,Nakae Y,Kondo T

更新日期：1997-08-01 00:00:00