A pancreatic abscess 7 years after a pancreatojejunostomy for calcifying chronic pancreatitis.

abstract：:Involvement of the gastroduodenum is extremely rare in Crohn's disease. For obstructing duodenal Crohn's disease, bypass procedures have traditionally been selected. However, more recently, strictureplasty has become an acceptable surgical option. We treated two Crohn's disease patients with short proximal duodenal st...

journal_title：Journal of gastroenterology

authors： Takesue Y,Yokoyama T,Akagi S,Ohge H,Murakami Y,Imamura Y,Uemura K,Kanehiro T,Matsuura Y

更新日期：2000-12-01 00:00:00

abstract：:A 21-year-old man with diarrhea and edema was admitted to our hospital and diagnosed with protein-losing enteropathy caused by primary intestinal lymphangiectasia. He was placed, in turn, on a low-fat diet, an elemental diet, and, subsequently, fasting therapy with total parenteral nutrition (TPN) support. However, hi...

journal_title：Journal of gastroenterology

authors： Kuroiwa G,Takayama T,Sato Y,Takahashi Y,Fujita T,Nobuoka A,Kukitsu T,Kato J,Sakamaki S,Niitsu Y

更新日期：2001-02-01 00:00:00

abstract：:Diagnosis of chronic pancreatitis in its early stage is an extremely difficult task. If the genetic predispositions are identified, it may help make possible the earlier diagnosis of chronic pancreatitis or the detection of patients at risk. There are two major hypotheses about the pathogenesis of chronic pancreatitis...

journal_title：Journal of gastroenterology

authors： Naruse S,Fujiki K,Ishiguro H

更新日期：2007-01-01 00:00:00

abstract：:Various types of polyunsaturated fatty acids (PUFAs) have been suggested to exert different effects on the colon in terms of promotion or inhibition of tumor development. Results of in vitro and in vivo studies are, however, inconsistent and it remains unclear whether or not the cellular effects of PUFAs change along ...

journal_title：Journal of gastroenterology

authors： Tsai WS,Nagawa H,Kaizaki S,Tsuruo T,Muto T

更新日期：1998-04-01 00:00:00

abstract：:In 1992, a seroepidemiologic study was carried out among hemodialysis patients and the general population in Fukuoka and Okinawa, Japan to determine the presence of hepatitis C virus (HCV) infection and HCV viremia. The markers used were antibody to HCV, determined by second-generation assay (anti-HCV), and HCV RNA, d...

journal_title：Journal of gastroenterology

authors： Hayashi J,Yoshimura E,Nabeshima A,Kishihara Y,Ikematsu H,Hirata M,Maeda Y,Kashiwagi S

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:We recently reported the real-world changes in the etiologies of liver cirrhosis (LC) based on nationwide survey data and assessed the etiologies of LC with hepatocellular carcinoma (HCC). METHODS:Fifty-five participants from 68 institutions provided data on 23,637 patients with HCC-complicated LC. The chan...

journal_title：Journal of gastroenterology

authors： Enomoto H,Ueno Y,Hiasa Y,Nishikawa H,Hige S,Takikawa Y,Taniai M,Ishikawa T,Yasui K,Takaki A,Takaguchi K,Ido A,Kurosaki M,Kanto T,Nishiguchi S,Japan Etiology of Liver Cirrhosis Study Group in the 54th Annual Meeting of JSH.

更新日期：2020-11-20 00:00:00

abstract：:Inflammatory bowel disease (IBD) could be curable by "immune rest" and correction of the genetic predisposition inherent in allogeneic hematopoietic stem cell transplantation. However, balancing risks against benefits remains challenging. The application of mesenchymal stem cells (MSCs) serving as a site-regulated "dr...

journal_title：Journal of gastroenterology

authors： Nagaishi K,Arimura Y,Fujimiya M

更新日期：2015-03-01 00:00:00

abstract：:An association between macrovascular thrombosis and idiopathic inflammatory bowel disease has been described, although very few well-documented cases have been published. We report on a 39-year-old woman who presented with right hemifacial and upper limb edema that was shown to be due to an extensive right brachioceph...

journal_title：Journal of gastroenterology

authors： Ribeiro JM,Rebocho L,Lucas MB,Campos P,Victorino RM

更新日期：2003-01-01 00:00:00

abstract：:The clinical significance of the measurement of c-erbB-2 oncogene product was evaluated. The subjects consisted of 404 patients, including 248 with cancer of the digestive organs and 128 with benign digestive diseases. Serum c-erbB-2 protein levels were measured by sandwich immunoenzyme assay. The positive rates of c-...

journal_title：Journal of gastroenterology

authors： Motoo Y,Sawabu N,Yamaguchi Y,Mouri I,Yamakawa O,Watanabe H,Ohta H,Okai T,Makino H

更新日期：1994-10-01 00:00:00

abstract：:Inflammatory cells in the gastric epithelium and direct cell damage are important effects of H. pylori infection in causing gastroduodenal diseases. The aim of this study was to determine whether H. Pylori possessing the cagA gene and vacuolating cytotoxin activity (cagA+/tox+) has these toxigenicities. The detection ...

journal_title：Journal of gastroenterology

authors： Kodama K,Fujioka T,Ito A,Kodama R,Nasu M

更新日期：1998-01-01 00:00:00

abstract：:An expert meeting was organized by the Swedish and Norwegian Medical Products Agencies in September 1995 in order to review the current literature and opinions on detection and treatment of Helicobacter pylori. Ten people from these Agencies and 23 experts participated in the workshop and all were involved in the fina...

journal_title：Journal of gastroenterology

authors： Unge P

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Although colorectal cancer (CRC) is one of the most common causes of cancer mortality, early-stage detection improves survival rates dramatically. Because cancer impacts important metabolic pathways, the alteration of metabolite levels as a potential biomarker of early-stage cancer has been the focus of many...

journal_title：Journal of gastroenterology

authors： Uchiyama K,Yagi N,Mizushima K,Higashimura Y,Hirai Y,Okayama T,Yoshida N,Katada K,Kamada K,Handa O,Ishikawa T,Takagi T,Konishi H,Kuriu Y,Nakanishi M,Otsuji E,Itoh Y,Naito Y

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:LYVE-1, a specific marker of lymphatics, is expressed in hepatic sinusoidal endothelium. A previous study revealed that LYVE-1 expression in sinusoidal endothelium was reduced in cirrhosis. However, it is still obscure how LYVE-1 expression in sinusoidal endothelium was reduced during the disease progression...

journal_title：Journal of gastroenterology

authors： Arimoto J,Ikura Y,Suekane T,Nakagawa M,Kitabayashi C,Iwasa Y,Sugioka K,Naruko T,Arakawa T,Ueda M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:There have been few epidemiological studies on gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in Japan. METHODS:We examined the epidemiology of GEP-NETs [pancreatic endocrine tumors (PETs) and gastrointestinal neuroendocrine tumors (GI-NETs)] in Japan in 2005 using a nationwide stratified random sa...

journal_title：Journal of gastroenterology

authors： Ito T,Sasano H,Tanaka M,Osamura RY,Sasaki I,Kimura W,Takano K,Obara T,Ishibashi M,Nakao K,Doi R,Shimatsu A,Nishida T,Komoto I,Hirata Y,Nakamura K,Igarashi H,Jensen RT,Wiedenmann B,Imamura M

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Although previous studies have indicated that serum pepsinogen I levels, as well as the pepsinogen I/II ratio, were positively correlated with maximal gastric output, the relationship may be different between Helicobacter pylori-negative and -positive subjects. The aim of this study was to investigate the re...

journal_title：Journal of gastroenterology

authors： Iijima K,Sekine H,Koike T,Imatani A,Ohara S,Shimosegawa T

更新日期：2005-10-01 00:00:00

abstract：:Adenocarcinoma of the small intestine is uncommon. Due to this paucity and the lack of specificity of symptoms, patients are usually seen late in the course of their illness, when curative therapy, mainly represented by extensive surgical resection, is unlikely. The authors report a case of primary well-differentiated...

journal_title：Journal of gastroenterology

authors： Koyama S,Araki M,Yuhara K,Murata Y,Fukutomi H,Atake S,Gohongi T,Yuzawa K,Fukao K,Kikuchi M

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Insulin-like growth factor (IGF)-I receptor (IGF-IR) signaling plays important parts in both the tumorigenicity and progression of digestive/gastrointestinal malignancies. In this study, we sought to test the effectiveness of a practical approach to blocking IGF-IR signaling using RNA interference d...

journal_title：Journal of gastroenterology

authors： Wang Y,Adachi Y,Imsumran A,Yamamoto H,Piao W,Li H,Ii M,Arimura Y,Park MY,Kim D,Lee CT,Carbone DP,Imai K,Shinomura Y

更新日期：2010-02-01 00:00:00

abstract：:Cold restraint stress (CRS) induced vagal-dependent corpus mucosal erosions with hemorrhage in rats. Aggressive factors such as gastric acid, pepsin, and high-amplitude contractions have been reported to be responsible for inducing the formation of gastric lesions. Thyrotropin-releasing hormone (TRH) microinjected int...

journal_title：Journal of gastroenterology

authors： Kaneko H,Taché Y,Kusugami K

更新日期：2002-11-01 00:00:00

abstract：:In this study, we used magnetic resonance (MR) imaging to measure portal blood flow in 12 healthy controls and 17 cirrhotics while they were breath-holding after inspiration and after expiration. We then compared the results with measurements made during normal respiration in the healthy controls and cirrhotics. Blood...

journal_title：Journal of gastroenterology

authors： Sugano S,Yamamoto K,Sasao K,Watanabe M

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Oxidative stress (OS) plays an important role in the progression of chronic liver disease and hepatocarcinogenesis. However, the role of OS in the progression of hepatocellular carcinoma (HCC) is unclear. The aim of this study was to assess whether OS promotes angiogenesis in HCC. METHODS:The expressions of...

journal_title：Journal of gastroenterology

authors： Jo M,Nishikawa T,Nakajima T,Okada Y,Yamaguchi K,Mitsuyoshi H,Yasui K,Minami M,Iwai M,Kagawa K,Itoh Y,Yoshikawa T

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:We recently reported that the presence of a papillary adenocarcinoma (pap) component was an independent risk factor for lymphatic involvement in endoscopically resected early gastric cancer (EGC). This study aimed to investigate the potential association between the presence of a pap component in EGC and lym...

journal_title：Journal of gastroenterology

authors： Sekiguchi M,Kushima R,Oda I,Suzuki H,Taniguchi H,Sekine S,Fukagawa T,Katai H

更新日期：2015-04-01 00:00:00

abstract：:The 13C-urea breath test (13C-UBT) is a non-invasive method for detecting Helicobacter pylori. This study was performed to determine the cutoff value and evaluate the sensitivity and specificity of 13C-UBT in Taiwan. 13C-Urea (100 mg of 99% 13C-labeled urea) was dissolved in 50 ml sterile water for the test. The test ...

journal_title：Journal of gastroenterology

authors： Wang WM,Lee SC,Ding HJ,Jan CM,Chen LT,Wu DC,Liu CS,Peng CF,Chen YW,Huang YF,Chen CY

更新日期：1998-06-01 00:00:00

abstract：:Cyclin D1 overexpression is remarkably frequent in several human carcinomas and is believed to be a critical event in oncogenesis. We examined cyclin D1 expression, p53 expression, and the Ki-67 labeling index by immunostaining in human gallbladder mucosa in conditions varying from normal to malignant tissue. We also ...

journal_title：Journal of gastroenterology

authors： Itoi T,Shinohara Y,Takeda K,Nakamura K,Takei K,Sanada J,Horibe T,Saito T,Kasuya K,Ebihara Y

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:This study aimed to develop a model to predict the development of severe anemia during pegylated interferon alpha-2b plus ribavirin combination therapy. METHODS:Data were collected from 1081 genotype 1b chronic hepatitis C patients who were treated at 6 hospitals in Japan. These patients were randomly assig...

journal_title：Journal of gastroenterology

authors： Hiramatsu N,Kurosaki M,Sakamoto N,Iwasaki M,Sakamoto M,Suzuki Y,Sugauchi F,Tamori A,Kakinnuma S,Matsuura K,Izumi N

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:Hepatic steatosis is frequently observed in subjects with metabolic syndrome (MS). In type 2 diabetics, it is independently associated with cardiovascular diseases. In order to confirm and extend this finding, a large group of patients with risk factors for atherosclerosis was studied. METHODS:Carotid atherosc...

journal_title：Journal of gastroenterology

authors： Carallo C,Mancuso G,Mauro G,Laghi F,Madafferi B,Irace C,Gnasso A,Scavelli F,Dell'Aquila F,Bartone M,Gullo F,Ferraro M,Spagnuolo V,Belmonte M,Ferrara A,Silvano Rotondaro A,Brandolino N,Parasporo F,Scopelliti F

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) occurs in chronic hepatitis B (CH-B) patients even after treatment with nucleos(t)ide analogues (NAs) by a mechanism involving an association between the oncogenic factors of integrated HBV and liver fibrosis. An association has been demonstrated between advanced chronic liver ...

journal_title：Journal of gastroenterology

authors： Kawaguchi K,Honda M,Ohta H,Terashima T,Shimakami T,Arai K,Yamashita T,Sakai Y,Yamashita T,Mizukoshi E,Komura T,Unoura M,Kaneko S

更新日期：2018-06-01 00:00:00

abstract：:Cholecystokinin (CCK) receptor antagonists have been reported on have an inhibitory effect on acute experimental pancreatitis, but their long-term administration is also reported to block pancreatic regeneration. We examined whether the short-term administration of KSG-504 (KSG), a synthetic CCK-A receptor antagonist,...

journal_title：Journal of gastroenterology

authors： Okumura Y,Inoue H,Fujiyama Y,Bamba T

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Anemia of inflammation, commonly observed in patients with chronic diseases, is associated with decreased serum iron. Hepcidin, mainly produced by hepatocytes in a STAT3- and/or SMAD-dependent manner, is involved in iron homeostasis. What remains to be established is whether or not the hepatic IL-6/STAT3 sig...

journal_title：Journal of gastroenterology

authors： Sakamori R,Takehara T,Tatsumi T,Shigekawa M,Hikita H,Hiramatsu N,Kanto T,Hayashi N

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to elucidate the role of nuclear factor kappaB (NF-kappaB) in the development of gastric ischemia-reperfusion (GI-R) injury and in mediating the effects of angiotensin II (Ang II) in the paraventricular nucleus (PVN) on GI-R injury. METHODS:GI-R injury was induced in rats by cl...

journal_title：Journal of gastroenterology

authors： Zhang YM,Wei EQ,Hu X,Qiao WL,Shi Y,Xu M,Zhang JF

更新日期：2008-01-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease in industrialized countries worldwide, and has become a serious public health issue not only in Western countries but also in many Asian countries including Japan. Within the wide spectrum of NAFLD, nonalcoholic steato...

journal_title：Journal of gastroenterology

authors： Watanabe S,Hashimoto E,Ikejima K,Uto H,Ono M,Sumida Y,Seike M,Takei Y,Takehara T,Tokushige K,Nakajima A,Yoneda M,Saibara T,Shiota G,Sakaida I,Nakamuta M,Mizuta T,Tsubouchi H,Sugano K,Shimosegawa T,Japanese Society

更新日期：2015-04-01 00:00:00