Abstract:
:A 21-year-old man with diarrhea and edema was admitted to our hospital and diagnosed with protein-losing enteropathy caused by primary intestinal lymphangiectasia. He was placed, in turn, on a low-fat diet, an elemental diet, and, subsequently, fasting therapy with total parenteral nutrition (TPN) support. However, his symptoms were not relieved, but, rather were exacerbated. On the 45th day of hospitalization, octreotide therapy was initiated. After 2 weeks of treatment, his clinical symptoms, as well as hypoproteinemia and hypoalbuminemia, gradually became alleviated. The improvement was confirmed in terms of scintigraphy, endoscopy, and histology of the duodenum. The patient remained healthy until 6 months after the commencement of octreotide treatment, when he discontinued octreotide at his own discretion, at which point the symptoms recurred. Resumption of the drug, however, again brought about remission, which has continued until the present, March 2000. Thus, octreotide therapy is one modality which may be useful for refractory primary intestinal lymphangiectasia.
journal_name
J Gastroenteroljournal_title
Journal of gastroenterologyauthors
Kuroiwa G,Takayama T,Sato Y,Takahashi Y,Fujita T,Nobuoka A,Kukitsu T,Kato J,Sakamaki S,Niitsu Ydoi
10.1007/s005350170142subject
Has Abstractpub_date
2001-02-01 00:00:00pages
129-32issue
2eissn
0944-1174issn
1435-5922journal_volume
36pub_type
杂志文章abstract:BACKGROUND:Gastric marker mucins (MUC5AC and MUC6) and intestinal marker molecules (MUC2 and CD10) have been used to determine the cell lineage of epithelial cell of gastric carcinoma (GC). METHODS:To clarify the characteristics of Epstein-Barr virus (EBV)-associated GC, 18 cases were immunohistochemically evaluated a...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-006-1841-y
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Using cDNA microarray analysis that displays a total of 8734 mouse genes, we have identified 21 known and novel transcripts, including mouse expressed sequence tags (ESTs) that were consistently up- or downregulated in the fundus of wild-type mice and W/W(V) mice, where intramuscular interstitial cells of Ca...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-003-1283-8
更新日期:2004-01-01 00:00:00
abstract::Endoscopic surveillance of Barrett's esophagus has become a foundation of the management of esophageal adenocarcinoma (EAC). Surveillance for Barrett's esophagus commonly involves periodic upper endoscopy with biopsies of suspicious areas and random four-quadrant biopsies. However, targeted biopsies using narrow-band ...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.1007/s00535-018-1491-x
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:A new capsule endoscope has been developed by Olympus Medical Systems. The visualization and usefulness of its real-time image viewer for gastric transit abnormality were evaluated by using this new device. METHODS:Thirty-seven consecutive patients were enrolled. In cases of gastric transit abnormality (gas...
journal_title:Journal of gastroenterology
pub_type: 临床试验,杂志文章
doi:10.1007/s00535-007-2140-y
更新日期:2008-01-01 00:00:00
abstract::To evaluate the diagnostic utility of blood biochemical parameters in assessing degree of hepatic fibrosis, serum levels of aminoterminal type III procollagen peptide (P III P), type IV collagen (IV-collagen), 7S domain of type IV collagen (7S-collagen), and hyaluronan (HA) were measured in 54 patients with chronic vi...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/BF02934493
更新日期:1997-06-01 00:00:00
abstract::Pyogenic granulomas represent the aquisition of vasodilative granulation tissue in the skin or mucosa. They are extremely rare in the alimentary tract, other than in the oral cavity. Here, we report a case of pyogenic granuloma arising from the gastric mucosa. An 82-year-old man was admitted to our hospital because of...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.1007/s00535-004-1579-3
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Ulcerative colitis (UC) is characterized by chronic inflammation in the colon and epigenetic factors underlying the occurrence. Circular RNAs (circRNAs) have been under intensive focus due to the circular construct and gene-regulating functions. However, the changes and roles of circRNAs in UC remain unknown...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-019-01585-7
更新日期:2019-09-01 00:00:00
abstract::Helicobacter pylori infection has been found to decrease the expression of antral somatostatin and to increase the release of the acid-stimulating hormone gastrin. The reversal of these changes in gut hormones by the eradication of H. pylori, and in-vivo and in-vitro studies in animals either infected with H. pylori o...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.1007/s005350200000
更新日期:2002-01-01 00:00:00
abstract::Both reflex and sensory mechanisms control the function of the stomach, and disturbances in these mechanisms may explain the pathophysiology of disorders of gastric function. The objective of this report is to perform a literature-based critical analysis of new, relevant or conflicting information on gastric sensitivi...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.1007/s00535-013-0917-8
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The relative contribution of gastric acid secretion and Helicobacter pylori infection to low-dose aspirin-induced gastropathy remains to be clarified. This is partly because the capability of the infection to modify gastric acid secretion complicates the interaction. The aim of this study was to estimate the...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-011-0385-y
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:The p53 tumor suppressor protein plays a fundamental role in maintaining genomic integrity through its ability to arrest the cell cycle in G1 and induce apoptosis. The proapoptotic activity of p53 seems to be strictly related to proline-rich regions, homologous to the SH3 binding domain. In the literature, r...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-007-2026-z
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Previous studies investigating the impact of tumor location on colorectal cancer prognosis only compared two groups by location, e.g., 'right-sided colon vs. left-sided colon,' 'colon vs. rectum,' and 'right-sided (right-sided colon) vs. left-sided (left-sided colon and rectum).' This nationwide multicenter ...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-020-01706-7
更新日期:2020-10-01 00:00:00
abstract::As an increase in gastroesophageal reflux disease (GERD) has been reported in Japan, and public interest in GERD has been increasing, the Japanese Society of Gastroenterology published the Evidence-based Clinical Practice Guidelines for GERD (1st edition) in 2009. Six years have passed since its publication, and there...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,实务指引,评审
doi:10.1007/s00535-016-1227-8
更新日期:2016-08-01 00:00:00
abstract::Ulcerative colitis is a chronic inflammatory disease of colonic mucosa in which the pathogenesis of any immunological disorders would likely be related. Various circulating autoantibodies have been reported in patients with ulcerative colitis, although their possible roles in this disease process have not yet been cla...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/BF03326407
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:The model for end-stage liver disease (MELD) is useful for assessing the recipients of liver transplants, namely, deceased-donor transplantation. The application of MELD for living donor liver transplantation (LDLT) is under investigation. Thus, the aim of this study was to analyze the impact of the MELD sco...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-006-1887-x
更新日期:2006-10-01 00:00:00
abstract::The localization and distribution of gamma delta T cell receptor (TCR)-positive cells (gamma delta T cells) in hepatocellular carcinoma capsules was investigated immunohistochemically at both light and electron microscopic levels. Most of the mononuclear cells infiltrating the tumor capsules were CD3-positive. Togethe...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/BF02347508
更新日期:1995-06-01 00:00:00
abstract::The aim of this study was to examine the diurnal variations in ornithine decarboxylase (ODC) activity and apoptosis in the small intestinal mucosa of Mongolian gerbils. First, the feeding, drinking, and ambulatory patterns of the gerbils were recorded. The results indicated that Mongolian gerbils lost diurnal cyclicit...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s005350070088
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:It remains unknown whether the Rome III criteria can exclude organic colonic lesions prior to the diagnosis of irritable bowel syndrome (IBS). We evaluated the colonoscopy results of patients meeting the Rome III criteria for the diagnosis of IBS to determine the presence of organic colonic lesions. METHODS...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00535-012-0573-4
更新日期:2012-10-01 00:00:00
abstract::We report a 13-year-old girl who presented with hepatic failure and hemolytic anemia. Laboratory findings showed a normal serum copper level (104 microg/dl), high urinary copper level (2370 microg/dl), and low serum ceruloplasmin level (14.3 microg/dl). Slit-lamp examination revealed Kayser-Fleischer rings on her corn...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
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更新日期:2005-06-01 00:00:00
abstract::Gastric mucosal lesions are an important complication in endotoxemia. In order to define the role played by the vagus nerve and endothelial-derived relaxing factor (EDRF) in gastric mucosal blood flow, an investigation was carried out on four groups of rats: a control group; a group given lipopolysaccharide (LPS, 5 mg...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/BF01211368
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:Oropharyngeal dysphagia (OD) is a major gastrointestinal motility disorder that causes severe nutritional and respiratory complications in elderly and neurological patients. In an earlier study, we found that stimulation of pharyngeal sensory neurons by capsaicinoids acting on transient receptor potential va...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00535-013-0920-0
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Evidence suggests that rates of gastroesophageal reflux disease are increasing in the Asia-Pacific region, where patients tend to have predominantly non-erosive reflux disease as opposed to erosive (reflux) esophagitis. At present, data for the responsiveness of non-erosive reflux disease to proton pump inhi...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00535-011-0402-1
更新日期:2011-07-01 00:00:00
abstract::Cytosolic phospholipase A2 (PLase A2) is activated by low Ca2+ concentrations and translocates from the cytosol to the cell membrane, releasing arachidonic acid; the arachidonic acid cascade then leads to the production of many inflammatory mediators. The aim of this study, accordingly, was to investigate the role of ...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s005350050215
更新日期:1999-02-01 00:00:00
abstract::The requirement for well spread out chromosomes for the cytogenetic analysis of primary gastrointestinal tumors led us to develop new techniques. These techniques involved two main procedures: (1) preliminary incubation with culture medium in the presence of collagenase, Dispase, and colcemid, for 3 h, and (2) treatme...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/BF02355049
更新日期:1996-08-01 00:00:00
abstract::Although polycystic liver disease (PLD) is known to be associated with autosomal dominant polycystic kidney disease, a finding of PLD with pancreatic ductal adenocarcinoma is extremely rare. We have experienced one such case of a ductal adenocarcinoma of the pancreas in a patient with Potter type III cystic disease of...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s005350170088
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:In acute pancreatitis, pancreatic phospholipase A(2) (PLA2) in the circulating blood hydrolyzes phospholipids contained in plasma lipoproteins, liberating eicosanoid precursors that are subsequently converted to various eicosanoids. The pathophysiological significance of eicosanoid synthesis via this pathway...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-006-1892-0
更新日期:2006-11-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-009-0159-y
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Little is known about the difference in enhancement patterns of hepatocellular carcinoma (HCC) during multistep hepatocarcinogenesis between the post-vascular phase of Sonazoid-enhanced ultrasonography (SEUS) and hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriamine (Gd-EOB-DTPA)-enhanced MRI, as...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-013-0859-1
更新日期:2014-06-01 00:00:00
abstract::Although stomal varices are a rare complication, bleeding stomal varices often need to be treated owing to symptoms of hypovolemic shock, recurrence of stomal bleeding, or deterioration in the quality of life. Various treatment strategies for the management of bleeding stomal varices have thus far been reported. We re...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-006-1960-5
更新日期:2007-01-01 00:00:00
abstract::There is an abundance of evidence that nitric oxide plays a critical role in regulating several components of gastrointestinal mucosal defense. Suppression of nitric oxide synthesis increases susceptibility to injury, while administration of nitric oxide donors increases resistance to injury. On the other hand, nitric...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.1007/s005350050178
更新日期:1998-12-01 00:00:00