Percutaneous microwave and radiofrequency ablation for hepatocellular carcinoma: a retrospective comparative study.


BACKGROUND:Percutaneous microwave ablation and radiofrequency ablation are two commonly used modalities for the treatment of hepatocellular carcinoma; however, comparisons of them have not been documented adequately. METHODS:Of 102 patients with biopsy-proved hepatocellular carcinoma, 49 (98 nodules) were treated percutaneously with microwave ablation and 53 (72 nodules) with radiofrequency ablation. The local tumor control, complications related to treatment, and long-term results of the two modalities were compared retrospectively. RESULTS:The complete ablation rates were 94.9% (93/98) using microwave ablation vs 93.1% (67/72) using radiofrequency ablation (P = 0.75), and no significant differences were found either in the ablation of tumors of 3.0 cm or less (P = 1.00) or in those of more than 3.0 cm (P = 1.00) between the two modalities. The local recurrence rates were 11.8% (11/93) using microwave ablation vs 20.9% (14/67) using radiofrequency ablation (P = 0.12), and there were no significant differences between the two modalities either in tumors of 3.0 cm or less (P = 0.36) or in those of more than 3.0 cm (P = 0.82). The rates of major complications associated with microwave ablation and radiofrequency ablation were 8.2% (4/49) vs 5.7% (3/53; P = 0.71). The disease-free survival rates in the microwave ablation group were 45.9%, 26.9%, 26.9%, and 13.4% at 1, 2, 3, and 4 years, respectively, and those in the radiofrequency ablation group were 37.2%, 20.7%, and 15.5% at 1, 2 and 3 years, respectively (P = 0.53). The 1-, 2-, 3-, and 4-year cumulative survival rates for patients who underwent microwave ablation were 81.6%, 61.2%, 50.5%, and 36.8%, respectively, and for patients who underwent radiofrequency ablation the rates were 71.7%, 47.2%, 37.6%, and 24.2%, respectively (P = 0.12). CONCLUSIONS:Percutaneous microwave ablation and radiofrequency ablation are both effective methods in treating hepatocellular carcinomas. The local tumor control, complications related to treatment, and long-term survivals were equivalent for the two modalities.


J Gastroenterol


Lu MD,Xu HX,Xie XY,Yin XY,Chen JW,Kuang M,Xu ZF,Liu GJ,Zheng YL




Has Abstract


2005-11-01 00:00:00












  • A population-based cohort study for the risk factors of HCC among hepatitis B virus mono-infected subjects in Japan.

    abstract:BACKGROUND:There have only been a few prospective studies investigating risk factors associated with the development of hepatocellular carcinoma (HCC) among chronic hepatitis B patients all over the world, and no study has been conducted in Japanese population. METHODS:A population-based cohort consisting of 19393 sub...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Kusakabe A,Tanaka Y,Inoue M,Kurbanov F,Tatematsu K,Nojiri S,Joh T,Tsugane S,Mizokami M

    更新日期:2011-01-01 00:00:00

  • Gastrojejunal fistula caused by gastric ulcer.

    abstract::We report a case of gastrojejunal fistula caused by benign gastric ulcer, a very rare condition. The patient was an 81-year-old-woman who had had multiple recurrences of gastric ulcer. She also had diabetes mellitus. She was admitted to our hospital because of a left femoral head fracture, necessitating a mechanical b...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Matsuoka M,Yoshida Y,Hayakawa K,Fukuchi S

    更新日期:1998-04-01 00:00:00

  • A pancreatic abscess 7 years after a pancreatojejunostomy for calcifying chronic pancreatitis.

    abstract::We present herein a case of a 75-year-old Japanese man who had developed a pancreatic abscess 7 years after a longitudinal pancreatojejunostomy for chronic pancreatitis. The patient, a heavy drinker of alcohol, underwent surgical decompression of a ductal obstruction to relieve persistent abdominal pain due to severel...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Suzuki A,Matsunaga T,Aoki S,Hirayama T,Nakagawa N,Shibata K,Yabana T,Kawasaki H,Takasaka H,Sasaki K,Katsuramaki T,Mukaiya M,Hirata K,Imai K

    更新日期:2002-01-01 00:00:00

  • Treatment outcomes after splenectomy with gastric devascularization or balloon-occluded retrograde transvenous obliteration for gastric varices: a propensity score-weighted analysis from a single institution.

    abstract:BACKGROUND:Although balloon-occluded retrograde transvenous obliteration (BRTO) is often selected to treat gastric varices caused by portal hypertension, data comparing BRTO and splenectomy with gastric devascularization (Sp + Dev) are limited. METHODS:From January 2009 to February 2018, 100 patients with gastric vari...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Oshita K,Ohira M,Honmyo N,Kobayashi T,Murakami E,Aikata H,Baba Y,Kawano R,Awai K,Chayama K,Ohdan H

    更新日期:2020-09-01 00:00:00

  • Living-related partial liver transplantation for decompensated hepatitis B without reactivation of hepatitis B in the following 30 months.

    abstract::We report a case of living-related partial liver transplantation for decompensated hepatitis B without reactivation of hepatitis B in the following 30 months, and we analyze the factors that indicate a favorable prognosis for transplantation. The 42-year-old female patient received continuously administered lamivudine...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Hasegawa K,Hashimoto E,Kanai N,Ogawa M,Naritomi T,Taniai M,Takasaki K,Hayashi N

    更新日期:2001-09-01 00:00:00

  • Superior mesenteric artery syndrome: diagnosis and treatment from the gastroenterologist's view.

    abstract:BACKGROUND:Superior mesenteric artery syndrome (SMAS) is caused by compression of the third part of the duodenum between the superior mesenteric artery and the aorta. It occurs most frequently in patients with rapid weight loss. METHODS:We report two young patients, who each presented with a longstanding history of po...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Lippl F,Hannig C,Weiss W,Allescher HD,Classen M,Kurjak M

    更新日期:2002-01-01 00:00:00

  • The relationship between gallbladder disease and smoking and drinking habits in middle-aged Japanese.

    abstract:BACKGROUND:Few studies have investigated the association between smoking and ultrasonographically diagnosed gallbladder (GB) disease, and their results were uncertain. This study was conducted to examine the association between smoking and drinking and GB diseases. METHODS:A total of 9,947 subjects (age, 30-69 years; ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Okamoto M,Yamagata Z,Takeda Y,Yoda Y,Kobayashi K,Fujino MA

    更新日期:2002-01-01 00:00:00

  • Leukocytapheresis for steroid-dependent ulcerative colitis in clinical practice: results of a nationwide Spanish registry.

    abstract:BACKGROUND:Several small, prospective, open studies suggest that leukocytapheresis might be efficient in patients with steroid-dependent ulcerative colitis (UC). AIM:To evaluate the short- and long-term effectiveness of leukocytapheresis for the management of steroid-dependent UC in clinical practice. METHODS:A Web-b...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Cabriada JL,Domènech E,Ibargoyen N,Hernández V,Clofent J,Ginard D,Gutiérrez-Ibarluzea I,Hinojosa J

    更新日期:2012-04-01 00:00:00

  • Dieulafoy's vascular malformation of the jejunum: first case report of laparoscopic treatment.

    abstract::A case of Dieulafoy's vascular malformation of the jejunum treated by laparoscopic surgery is described. The patient was a 31-year-old-woman who had complained of melena and had severe anemia needing blood transfusion. Angiography revealed microaneurysms and hypervascularity of the jejunum in the area between the firs...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Mino A,Ogawa Y,Ishikawa T,Uchima Y,Yamazaki M,Nakamura S,Yukawa T,Matsumoto T,Arakawa T,Hirakawa K

    更新日期:2004-01-01 00:00:00

  • Therapy of metastatic pancreatic neuroendocrine tumors (pNETs): recent insights and advances.

    abstract::Neuroendocrine tumors (NETs) [carcinoids, pancreatic neuroendocrine tumors (pNETs)] are becoming an increasing clinical problem because not only are they increasing in frequency, but they can frequently present with advanced disease that requires diagnostic and treatment approaches different from those used in the neo...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Ito T,Igarashi H,Jensen RT

    更新日期:2012-09-01 00:00:00

  • Hepatic subcapsular hematoma after extracorporeal shock wave lithotripsy (ESWL) for pancreatic stones.

    abstract::We present a patient with complication of huge hepatic subcapsular hematoma after extracorporeal shock wave lithotripsy (ESWL) for pancreatic lithotripsy. The hematoma measured 78-110mm. Angiography showed a subcapsular hematoma, rather than a hematoma in the liver. In the arterial phase, the distal end of the small v...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Hirata N,Kushida Y,Ohguri T,Wakasugi S,Kojima T,Fujita R

    更新日期:1999-12-01 00:00:00

  • Nutritional therapy for Crohn's disease in Japan.

    abstract::In Japan, nutritional therapy as both a primary and as a secondary treatment is widely used for Crohn's disease (CD). The rationale for its use is based on a variety of reasons. The first is its ability to induce remission and to ameliorate the activity of intestinal lesions in the short term by enteral (EN) or by par...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Matsui T,Sakurai T,Yao T

    更新日期:2005-03-01 00:00:00

  • Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: a Japanese collaborative study.

    abstract:BACKGROUND:Depth of submucosal invasion (SM depth) in submucosal invasive colorectal carcinoma (SICC) is considered an important predictive factor for lymph node metastasis. However, no nationwide reports have clarified the relationship between SM depth and rate of lymph node metastasis. Our aim was to investigate the ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,多中心研究


    authors: Kitajima K,Fujimori T,Fujii S,Takeda J,Ohkura Y,Kawamata H,Kumamoto T,Ishiguro S,Kato Y,Shimoda T,Iwashita A,Ajioka Y,Watanabe H,Watanabe T,Muto T,Nagasako K

    更新日期:2004-06-01 00:00:00

  • Anemia in patients with colorectal cancer.

    abstract::Although anemia is one of the signs of colorectal cancer, the relationships between histological findings and hematological findings other than hemoglobin level have not been adequately investigated. We investigated the relationship between hematological findings, serum iron, and histological findings in 358 patients ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Sadahiro S,Suzuki T,Tokunaga N,Mukai M,Tajima T,Makuuchi H,Saito T

    更新日期:1998-08-01 00:00:00

  • The recovery of the PT-INR to less than 1.3 predicts survival in patients with severe acute liver injury.

    abstract:BACKGROUND:Acute liver failure is a potentially fatal disease of various etiologies for which liver transplantation is the only known curative treatment. Although the decision-making on transplantation is largely dependent on the severity of liver injury (based on predicting a fatal outcome), a statistical analysis to ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Mawatari S,Moriuchi A,Ohba F,Kawano T,Oda K,Takikawa Y,Takikawa H,Ido A,Tsubouchi H

    更新日期:2018-07-01 00:00:00

  • Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.

    abstract:BACKGROUND:Neutrophil elastase (NE) is a major secretory product from activated neutrophils and a major contributor to tissue destruction. However, little is known about the pathogenic contribution of NE to ulcerative colitis (UC). This study was designed to investigate the contribution of NE by measuring NE activity i...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Morohoshi Y,Matsuoka K,Chinen H,Kamada N,Sato T,Hisamatsu T,Okamoto S,Inoue N,Takaishi H,Ogata H,Iwao Y,Hibi T

    更新日期:2006-04-01 00:00:00

  • D-Penicillamine improved laparoscopic and histological findings of the liver in a patient with Wilson's disease: 3-year follow-up after diagnosis of Coombs-negative hemolytic anemia of Wilson's disease.

    abstract::We report a 13-year-old girl who presented with hepatic failure and hemolytic anemia. Laboratory findings showed a normal serum copper level (104 microg/dl), high urinary copper level (2370 microg/dl), and low serum ceruloplasmin level (14.3 microg/dl). Slit-lamp examination revealed Kayser-Fleischer rings on her corn...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Sakaida I,Kawaguchi K,Kimura T,Tamura F,Okita K

    更新日期:2005-06-01 00:00:00

  • Effect of arterial administration of a high molecular weight anti-tumor agent, styrene maleic acid neocarzinostatin, for multiple small liver cancer--a pilot study.

    abstract::To assess the efficacy of the zinostatin derivative, the anti-tumor agent, styrene-maleic acid neocarzinostatin, in treating multiple small liver cancers, 29 patients with multiple hepatocellular carcinoma of 3 cm or less in diameter were treated with intraarterial injections of this high molecular weight agent, mixed...

    journal_title:Journal of gastroenterology

    pub_type: 临床试验,杂志文章


    authors: Ikeda K,Saitoh S,Suzuki Y,Tsubota A,Koida I,Kobayashi M,Arase Y,Chayama K,Murashima N,Kumada H

    更新日期:1997-08-01 00:00:00

  • Alpha-fetoprotein-producing gastric carcinoma: biological properties of a cultured cell line.

    abstract::We describe a gastric carcinoma cell line that has been maintained in vitro for more than 10 years and retains the capacity to produce a large amount of alpha-fetoprotein. This cell line was isolated from a metastatic lymph node of a 63-year-old male patient with advanced gastric carcinoma (T2N3P0H0M0) who showed high...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Sekiguchi M,Fujii Y,Saito A,Suzuki T,Shiroko Y,Nakamura H,Hasumi K

    更新日期:1995-10-01 00:00:00

  • Does gastroesophageal reflux have an influence on bleeding from esophageal varices?

    abstract:BACKGROUND:Mucosal breaks induced by gastroesophageal reflux of gastric contents were more frequently found on the right anterior wall of the lower esophagus. Bleeding from esophageal varices may be also derived from gastroesophageal reflux. The circumferential location of the ruptured esophageal varices was evaluated ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Okamoto E,Amano Y,Fukuhara H,Furuta K,Miyake T,Sato S,Ishihara S,Kinoshita Y

    更新日期:2008-01-01 00:00:00

  • Infective dyspepsia in a heart transplant recipient.

    abstract::We report the coexistence of symptomatic viral, bacterial, and fungal infection of the upper gastrointestinal tract in a heart transplant recipient. Endoscopic findings were normal at all levels but, because of severe symptoms and recent conversion to positive serology for Cytomegalovirus, biopsies were taken. These s...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Huwez FU,McPhaden AR,Belcher PR,Naik SK,Wheatley DJ

    更新日期:1996-12-01 00:00:00

  • Intestinal microflora as a therapeutic target in inflammatory bowel disease.

    abstract::Although the causes of inflammatory bowel disease (IBD) remain incompletely understood, increasing evidence implicates intestinal microflora in the pathogenesis of these disorders. Alteration of intestinal flora therefore may offer a plausible therapeutic approach. Although recent data support a potential therapeutic ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Mitsuyama K,Toyonaga A,Sata M

    更新日期:2002-11-01 00:00:00

  • Long-term effects of Helicobacter pylori eradication in Mongolian gerbils.

    abstract:BACKGROUND:In this study, to clarify whether Helicobacter pylori eradication alters the course of the development of gastric mucosal changes in the stomach, we examined the long-term effects of H. pylori eradication on H. pylori-inoculated gerbils. METHODS:A total of 40 H. pylori-inoculated gerbils were randomized and...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Hirayama F,Takagi S,Yokoyama Y,Yamamoto K,Iwao E,Haga K

    更新日期:2002-01-01 00:00:00

  • Adhesion molecules and pancreatitis.

    abstract::Acute and chronic pancreatitises are gastrointestinal inflammatory diseases, the incidence of which is increasing worldwide. Most (~ 80%) acute pancreatitis (AP) patients have mild disease, and about 20% have severe disease, which causes multiple organ failure and has a high mortality rate. Chronic pancreatitis (CP) i...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Sato T,Shibata W,Maeda S

    更新日期:2019-02-01 00:00:00

  • Long-term follow-up study of Crohn's disease in Japan. The Research Committee of Inflammatory Bowel Disease in Japan.

    abstract::Two hundred and three patients with Crohn's disease seen at Kyushu University, Fukuoka University, and their affiliated centers from 1973 to 1988 were followed for 4.4 +/- 3.2 years (mean +/- SD), to evaluate the prognosis relative to life span and surgery. Cumulative survival rate and cumulative operation rate were c...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,多中心研究


    authors: Iida M,Yao T,Okada M

    更新日期:1995-11-01 00:00:00

  • Chemotherapy for metastatic gastric cancer: past, present, and future.

    abstract::Despite the numerous efforts of randomized studies on advanced gastric cancer, no globally accepted standard regimen has yet been established. Two triplet regimens have already demonstrated significant survival prolongation in Western studies. However, the benefit seems to be marginal, and these regimens may be replac...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Ohtsu A

    更新日期:2008-01-01 00:00:00

  • Breath hydrogen and methane excretion produced by commercial beverages containing dietary fiber.

    abstract::Soft drinks containing dietary fiber are popular in Japan. There seem to be two types, one containing polydextrose and the other, oligosaccharide. These beverages are claimed to be useful for constipation or obesity, but data are scanty. We examined four such fiber-containing beverages [Fibe-mini Otsuka Pharmaceutical...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Kondo T,Nakae Y

    更新日期:1996-10-01 00:00:00

  • C-reactive protein is an indicator of serum infliximab level in predicting loss of response in patients with Crohn's disease.

    abstract:BACKGROUND:The ability of serum infliximab level to predict clinical outcome in infliximab therapy in Crohn's disease is unclear. Here, we aimed to clarify the correlation between the timing of loss of response (LOR) to treatment and a decrease in serum infliximab level, and, in addition, to identify an indicator of in...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,多中心研究


    authors: Hibi T,Sakuraba A,Watanabe M,Motoya S,Ito H,Sato N,Yoshinari T,Motegi K,Kinouchi Y,Takazoe M,Suzuki Y,Matsumoto T,Kawakami K,Matsumoto T,Hirata I,Tanaka S,Ashida T,Matsui T

    更新日期:2014-02-01 00:00:00

  • Clinical importance of IL-22 cascade in IBD.

    abstract::IL-22 is a relatively new cytokine that is characterized by several unique biological properties. In the intestines, the effect of IL-22 is restricted mainly to non-lymphoid cells such as epithelial cells. Interestingly, the expression pattern and major cellular source of IL-22 have distinct difference between large a...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Mizoguchi A,Yano A,Himuro H,Ezaki Y,Sadanaga T,Mizoguchi E

    更新日期:2018-04-01 00:00:00

  • Portal venous blood flow while breath-holding after inspiration or expiration and during normal respiration in controls and cirrhotics.

    abstract::In this study, we used magnetic resonance (MR) imaging to measure portal blood flow in 12 healthy controls and 17 cirrhotics while they were breath-holding after inspiration and after expiration. We then compared the results with measurements made during normal respiration in the healthy controls and cirrhotics. Blood...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章


    authors: Sugano S,Yamamoto K,Sasao K,Watanabe M

    更新日期:1999-10-01 00:00:00