Hypertension as a paraneoplastic syndrome in hepatocellular carcinoma.

abstract：PURPOSE:Recent routine testing for liver function and anti-mitochondrial antibodies has increased the number of newly diagnosed patients with primary biliary cirrhosis (PBC). This study investigated the prognosis of asymptomatic PBC patients, focusing on age difference, to clarify its effect on the prognosis of PBC pat...

journal_title：Journal of gastroenterology

authors： Kubota J,Ikeda F,Terada R,Kobashi H,Fujioka S,Okamoto R,Baba S,Morimoto Y,Ando M,Makino Y,Taniguchi H,Yasunaka T,Miyake Y,Iwasaki Y,Yamamoto K

更新日期：2009-01-01 00:00:00

abstract：:This study was designed to clarify what differences the last 25 years have made in surgical results for patients with hepatocellular carcinoma (HCC). We examined results for 716 hepatectomized patients in four treatment eras: first era (1973-1980; n = 58), second era (1981-1985; n = 155), third era (1986-1990; n = 243...

journal_title：Journal of gastroenterology

authors： Yamanaka N,Takata M,Tanaka T,Yamanaka J,Yasui C,Ando T,Kuroda N,Maeda S,Okamoto E

更新日期：2000-01-01 00:00:00

abstract：:A case of heterotopic gastric mucosa in the fundus of the gallbladder is reported. A 23-year-old man, who had been healthy and asymptomatic, visited our hospital because of abnormal findings in a liver enzyme test given during a routine health screening. Ultrasonography demonstrated a highly echogenic polypoid mass in...

journal_title：Journal of gastroenterology

authors： Uchiyama S,Imai S,Suzuki T,Arita A,Takeda K,Sujino H,Kameda H

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy is the current standard of care for patients with chronic hepatitis C. Determining precisely the risk of serious adverse events (SAEs) and mortality from a single study is rather difficult because of the infrequency of such events. The aim of this s...

journal_title：Journal of gastroenterology

authors： Minami T,Kishikawa T,Sato M,Tateishi R,Yoshida H,Koike K

更新日期：2013-02-01 00:00:00

abstract：:We report a 54-year-old Japanese woman who developed liver tumors 102 months after hepatic resection for hepatocellular carcinoma (HCC) and percutaneous transluminal angioplasty (PTA) for membranous obstruction of the inferior vena cava (MOVC), which is one form of Budd-Chiari syndrome. In the present admission workup...

journal_title：Journal of gastroenterology

authors： Takamura M,Ichida T,Yokoyama J,Matsuda Y,Nomoto M,Aoyagi Y

更新日期：2004-07-01 00:00:00

abstract：:A 69-year-old woman was admitted to our hospital with fever and abdominal pain in the epigastric region. Abdominal ultrasonography demonstrated a well-defined hypoechoic mass in the epigastric region with encasement of the left hepatic lobe and stomach. Computed tomography confirmed a low-density mass, 20 cm in diamet...

journal_title：Journal of gastroenterology

authors： Kaibori M,Kawaguchi Y,Yokoigawa N,Yanagida H,Takai S,Kwon AH,Uemura Y,Kamiyama Y

更新日期：2003-01-01 00:00:00

abstract：:We describe a gastric carcinoma cell line that has been maintained in vitro for more than 10 years and retains the capacity to produce a large amount of alpha-fetoprotein. This cell line was isolated from a metastatic lymph node of a 63-year-old male patient with advanced gastric carcinoma (T2N3P0H0M0) who showed high...

journal_title：Journal of gastroenterology

authors： Sekiguchi M,Fujii Y,Saito A,Suzuki T,Shiroko Y,Nakamura H,Hasumi K

更新日期：1995-10-01 00:00:00

abstract：:Focal nodular hyperplasia (FNH) of the liver is a rare benign lesion that probably reflects a local hyperplastic response of hepatocytes to a vascular abnormality. Currently, the natural history of the disease remains largely unknown. We present a patient with FNH of the liver who was followed up for 4 years. A 22-yea...

journal_title：Journal of gastroenterology

authors： Ohmoto K,Honda T,Hirokawa M,Mitsui Y,Iguchi Y,Kuboki M,Yamamoto S

更新日期：2002-01-01 00:00:00

abstract：:Various types of polyunsaturated fatty acids (PUFAs) have been suggested to exert different effects on the colon in terms of promotion or inhibition of tumor development. Results of in vitro and in vivo studies are, however, inconsistent and it remains unclear whether or not the cellular effects of PUFAs change along ...

journal_title：Journal of gastroenterology

authors： Tsai WS,Nagawa H,Kaizaki S,Tsuruo T,Muto T

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:To examine gastric myoelectrical activity in patients with primary biliary cirrhosis (PBC). MATERIALS AND METHODS:The study comprised 11 female PBC patients (average age 53.4 years, range 43-70) and two aged-matched control groups: 11 (53.4 years, range 37-78) healthy women, and 10 female patients with chron...

journal_title：Journal of gastroenterology

authors： Kasicka-Jonderko A,Krusiec-Swidergoł B,Jonderko K,Musialik J,Gonciarz M,Błońska-Fajfrowska B,Gonciarz Z

更新日期：2009-01-01 00:00:00

abstract：:In this study, we used magnetic resonance (MR) imaging to measure portal blood flow in 12 healthy controls and 17 cirrhotics while they were breath-holding after inspiration and after expiration. We then compared the results with measurements made during normal respiration in the healthy controls and cirrhotics. Blood...

journal_title：Journal of gastroenterology

authors： Sugano S,Yamamoto K,Sasao K,Watanabe M

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Endoscopic sphincterotomy (ES) is widely performed in patients with common bile duct stones (CBDS). However, the long-term outcomes of patients following ES have not been sufficiently elucidated. Impaired papillary function following ES may result in additional late complications. In contrast, endoscopic pap...

journal_title：Journal of gastroenterology

authors： Doi S,Yasuda I,Mukai T,Iwashita T,Uemura S,Yamauchi T,Nakashima M,Adachi S,Shimizu M,Tomita E,Itoi T,Moriwaki H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Although it is less frequently encountered, mesenteric vein occlusion poses as important a problem as mesenteric artery occlusion. The energy metabolism of intestinal tissue during venous occlusion and reperfusion was studied. METHODS:Male Wistar rats were studied in four groups of 17 animals each. Intestin...

journal_title：Journal of gastroenterology

authors： Kimura M,Kataoka M,Kuwabara Y,Sato A,Sugiura M,Fujii Y

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) has not been reported for human hepatoma, because cancer cells only weakly take up the photosensitizer. Indocyanine green (ICG) is a photosensitizer normally excreted into the bile, and bile excretion is impaired in human hepatomas. We examined whether human hepatoma cell lines pre...

journal_title：Journal of gastroenterology

authors： Kaneko J,Inagaki Y,Ishizawa T,Gao J,Tang W,Aoki T,Sakamoto Y,Hasegawa K,Sugawara Y,Kokudo N

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) is characterized by chronic inflammation in the colon and epigenetic factors underlying the occurrence. Circular RNAs (circRNAs) have been under intensive focus due to the circular construct and gene-regulating functions. However, the changes and roles of circRNAs in UC remain unknown...

journal_title：Journal of gastroenterology

authors： Wang T,Chen N,Ren W,Liu F,Gao F,Ye L,Han Y,Zhang Y,Liu Y

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Patients with ulcerative colitis (UC) exhibit overproduction of reactive oxygen species (ROS) and imbalance of colonic microflora. We previously developed a novel redox nanoparticle (RNP(O)), which effectively scavenged ROS in the inflamed mucosa of mice with dextran sodium sulfate (DSS)-induced colitis afte...

journal_title：Journal of gastroenterology

authors： Vong LB,Yoshitomi T,Morikawa K,Saito S,Matsui H,Nagasaki Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Insulin-like growth factor (IGF)-I receptor (IGF-IR) signaling plays important parts in both the tumorigenicity and progression of digestive/gastrointestinal malignancies. In this study, we sought to test the effectiveness of a practical approach to blocking IGF-IR signaling using RNA interference d...

journal_title：Journal of gastroenterology

authors： Wang Y,Adachi Y,Imsumran A,Yamamoto H,Piao W,Li H,Ii M,Arimura Y,Park MY,Kim D,Lee CT,Carbone DP,Imai K,Shinomura Y

更新日期：2010-02-01 00:00:00

abstract：:Gastrointestinal symptoms such as abdominal pain, dyspepsia, and diarrhea are relatively nonspecific and a common cause for seeking medical attention. To date, it is challenging for physicians to differentiate between functional and organic gastrointestinal conditions and it involves the use of serological and endosco...

journal_title：Journal of gastroenterology

authors： Ikhtaire S,Shajib MS,Reinisch W,Khan WI

更新日期：2016-05-01 00:00:00

abstract：:We present herein a case of a 75-year-old Japanese man who had developed a pancreatic abscess 7 years after a longitudinal pancreatojejunostomy for chronic pancreatitis. The patient, a heavy drinker of alcohol, underwent surgical decompression of a ductal obstruction to relieve persistent abdominal pain due to severel...

journal_title：Journal of gastroenterology

authors： Suzuki A,Matsunaga T,Aoki S,Hirayama T,Nakagawa N,Shibata K,Yabana T,Kawasaki H,Takasaka H,Sasaki K,Katsuramaki T,Mukaiya M,Hirata K,Imai K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:There have only been a few prospective studies investigating risk factors associated with the development of hepatocellular carcinoma (HCC) among chronic hepatitis B patients all over the world, and no study has been conducted in Japanese population. METHODS:A population-based cohort consisting of 19393 sub...

journal_title：Journal of gastroenterology

authors： Kusakabe A,Tanaka Y,Inoue M,Kurbanov F,Tatematsu K,Nojiri S,Joh T,Tsugane S,Mizokami M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The risk for lymph node metastasis and the prognostic significance of pedunculated-type T1 colorectal carcinomas (CRCs) require further study. We aimed to assess the validity of the 2014 Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines based on long-term outcomes of pedunculated-type T1...

journal_title：Journal of gastroenterology

authors： Asayama N,Oka S,Tanaka S,Nagata S,Furudoi A,Kuwai T,Onogawa S,Tamura T,Kanao H,Hiraga Y,Okanobu H,Kuwabara T,Kunihiro M,Mukai S,Goto E,Shimamoto F,Chayama K

更新日期：2016-07-01 00:00:00

abstract：:To study the appropriate period for formalin fixation in order to detect p53 abnormalities in formalin-fixed tissue, we used seven surgically resected human colorectal cancer specimens. The immunohistochemical reactivity of p53 immunostaining and amplification of DNA by polymerase chain reaction (PCR) of the p53 gene ...

journal_title：Journal of gastroenterology

authors： Matsubayashi H,Watanabe H,Nishikura K,Ajioka Y,Maejima T,Kijima H,Saitoh T

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Primary biliary cirrhosis (PBC) is histopathologically characterized by chronic nonsuppurative destructive cholangitis and ductopenia of interlobular bile ducts. Bile duct injury is also often encountered in chronic viral hepatitis (CVH) and in autoimmune hepatitis (AIH). METHODS:In this study, we performed...

journal_title：Journal of gastroenterology

authors： Zen Y,Harada K,Sasaki M,Tsuneyama K,Matsui K,Haratake J,Sakisaka S,Maeyama S,Yamamoto K,Nakano M,Shimamatsu K,Kage M,Kurose N,Uchiyama A,Kaizaki Y,Toda G,Nakanuma Y

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Hypersensitive esophagus (HE) is defined by endoscopy-negative heartburn with a normal acid exposure time but positive symptom association probability (SAP) and/or symptom index (SI) on impedance-pH monitoring, and proton pump inhibitor (PPI) responsiveness. Functional heartburn (FH) is distinguished by nega...

journal_title：Journal of gastroenterology

authors： Frazzoni M,de Bortoli N,Frazzoni L,Furnari M,Martinucci I,Tolone S,Farioli A,Marchi S,Fuccio L,Savarino V,Savarino E

更新日期：2017-04-01 00:00:00

abstract：:We report the coexistence of symptomatic viral, bacterial, and fungal infection of the upper gastrointestinal tract in a heart transplant recipient. Endoscopic findings were normal at all levels but, because of severe symptoms and recent conversion to positive serology for Cytomegalovirus, biopsies were taken. These s...

journal_title：Journal of gastroenterology

authors： Huwez FU,McPhaden AR,Belcher PR,Naik SK,Wheatley DJ

更新日期：1996-12-01 00:00:00

abstract：:To assess the efficacy of the zinostatin derivative, the anti-tumor agent, styrene-maleic acid neocarzinostatin, in treating multiple small liver cancers, 29 patients with multiple hepatocellular carcinoma of 3 cm or less in diameter were treated with intraarterial injections of this high molecular weight agent, mixed...

journal_title：Journal of gastroenterology

authors： Ikeda K,Saitoh S,Suzuki Y,Tsubota A,Koida I,Kobayashi M,Arase Y,Chayama K,Murashima N,Kumada H

更新日期：1997-08-01 00:00:00

abstract：:We estimated the levels of free sialic acid and sialylated oligosaccharides excreted in the urine of normal donors (n = 10) and patients with gastric cancer (n = 6) and colorectal cancer (n = 4). The total sialic acid level in cancer patients was similar to that in normal donors. However, the ratios of glycosidically ...

journal_title：Journal of gastroenterology

authors： Shimada I,Shoji M,Futatsuya R,Katoh T,Kominato Y,Sakamoto T,Fujikura T

更新日期：1995-02-01 00:00:00

abstract：:The tight junction of pancreatic exocrine cells is thought to regulate paracellular permeability, and is a possible reflux route of pancreatic juice into the blood flow. Morphological changes in the tight junction of canine pancreatic acinar cells following intraductal hypertension and secretin stimulation were morpho...

journal_title：Journal of gastroenterology

authors： Akao S,Oya M,Akiyama H,Ishikawa H

更新日期：2000-01-01 00:00:00

abstract：:We report a case of Cruveihier-Baumgarten syndrome associated with portal vein thrombosis that developed, slowly during a 2-year period after endoscopic variceal sclerotherapy. The thrombosis led to the disappearance of the venous hum and the dilated abdominal wall veins characteristic of this syndrome. A 73-year-old ...

journal_title：Journal of gastroenterology

authors： Yamakawa O,Ohta H,Watanabe H,Motoo Y,Okai T,Kadoya M,Matsui O,Sawabu N

更新日期：1996-08-01 00:00:00

abstract：:Sixty-two colorectal adenomas 10 mm or less in diameter, resected endoscopically and fixed in formalin for 3 days or less, were evaluated with antiproliferating cell nuclear antigen/cyclin (PCNA) monoclonal antibody to investigate the cell proliferation kinetics. All lesions were tubular adenoma with low-grade atypia....

journal_title：Journal of gastroenterology

authors： Kobayashi M,Watanabe H,Ajioka Y,Honma T,Asakura H

更新日期：1994-04-01 00:00:00