Heterotopic gastric mucosa of the gallbladder.

abstract：BACKGROUND:The most commonly used methods for bowel preparation are polyethylene glycol-electrolyte lavage solution (PEG-ELS) and sodium phosphate. Both are problematic in children. The use of bisacodyl together with fleet enema has been suggested as an alternative; however, its use without dietary restriction is infer...

journal_title：Journal of gastroenterology

authors： Shaoul R,Haloon L

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:DNA microarray technology has enabled genomewide analysis of gene transcript levels, yielding insight into the molecular nature of liver disease. METHODS:We compared gene expression of liver biopsy specimens in 16 patients with different stages of chronic hepatitis B, five with autoimmune hepatitis (AIH), f...

journal_title：Journal of gastroenterology

authors： Furuta K,Sato S,Yamauchi T,Ozawa T,Harada M,Kakumu S

更新日期：2008-01-01 00:00:00

abstract：:This study was conducted to determine and compare serum trace metal levels in viral hepatitis-associated chronic liver disease. Of 98 patients aged 43 (+/- 13) [mean (+/- SD)] years, 83 (85%) were seropositive for hepatitis B surface antigen (HBsAg) and 15 (15%) were seropositive for anti-hepatitis C virus (HCV). Twen...

journal_title：Journal of gastroenterology

authors： Pramoolsinsap C,Promvanit N,Komindr S,Lerdverasirikul P,Srianujata S

更新日期：1994-10-01 00:00:00

abstract：:Little data are available regarding the effects of hepatitis virus serostatus and the severity of coexisting chronic inflammation on intrahepatic recurrence after hepatectomy for hepatocellular carcinoma (HCC). We investigated the extent to which these factors modified the prognosis of hepatectomized patients. A total...

journal_title：Journal of gastroenterology

authors： Yamanaka N,Takada M,Tanaka T,Yamanaka J,Yasui C,Ando T,Maeda S,Matsushita K,Okamoto E

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer is obstinate and resistant to gemcitabine, a standard chemotherapeutic agent for the disease. We previously showed a therapeutic effect of glycogen synthase kinase-3β (GSK3β) inhibition against gastrointestinal cancer and glioblastoma. Here, we investigated the effect of GSK3β inhibition on...

journal_title：Journal of gastroenterology

authors： Shimasaki T,Ishigaki Y,Nakamura Y,Takata T,Nakaya N,Nakajima H,Sato I,Zhao X,Kitano A,Kawakami K,Tanaka T,Takegami T,Tomosugi N,Minamoto T,Motoo Y

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The gap junction (GJ) plays important roles in the maintenance of tissue homeostasis, the control of cell growth and differentiation, and the prevention of experimental hepatocarcinogenesis. In this study, we examined the relationship between the expression of the GJ protein connexin (Cx) 32 in 24 human hepa...

journal_title：Journal of gastroenterology

authors： Nakashima Y,Ono T,Yamanoi A,El-Assal ON,Kohno H,Nagasue N

更新日期：2004-08-01 00:00:00

abstract：:Changes of hepatic sinusoids are crucial in the pathogenesis of liver cirrhosis and portal hypertension. Liver injury leads to distinct morphological abnormalities such as loss of sinusoidal fenestration, vasoconstriction, and angiogenesis as well as molecular changes. Communication between the two key cells in this h...

journal_title：Journal of gastroenterology

authors： Greuter T,Shah VH

更新日期：2016-06-01 00:00:00

abstract：:Patients with longstanding extensive colitis, both ulcerative colitis and Crohn's colitis, have an increased risk of developing colorectal cancer. Because of this risk, colonoscopic surveillance for neoplasia is recommended by most authorities. Although there has been no randomised controlled trial to demonstrate surv...

journal_title：Journal of gastroenterology

authors： Rutter MD

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Hypersensitive esophagus (HE) is defined by endoscopy-negative heartburn with a normal acid exposure time but positive symptom association probability (SAP) and/or symptom index (SI) on impedance-pH monitoring, and proton pump inhibitor (PPI) responsiveness. Functional heartburn (FH) is distinguished by nega...

journal_title：Journal of gastroenterology

authors： Frazzoni M,de Bortoli N,Frazzoni L,Furnari M,Martinucci I,Tolone S,Farioli A,Marchi S,Fuccio L,Savarino V,Savarino E

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Ghrelin, an appetite-promoting peptide secreted from the stomach, is reported to enhance preprandial acid output, possibly through stimulation of the cephalic phase. The present study was designed to clarify the dynamics of ghrelin in H(2) receptor (H(2)R)-null mice by genetic H(2)R knockout. METHODS:Fiftee...

journal_title：Journal of gastroenterology

authors： Arakawa M,Suzuki H,Minegishi Y,Fukushima Y,Masaoka T,Ishikawa T,Hosoda H,Kangawa K,Hibi T

更新日期：2007-09-01 00:00:00

abstract：:Preoperative biliary drainage (PBD) has been thought to be preferable regardless of the site of biliary strictures, e.g., distal or proximal strictures because PBD by endoscopy or interventional radiology decreases postoperative mortality and morbidity rates. However, recently, several studies have revealed that PBD s...

journal_title：Journal of gastroenterology

authors： Umeda J,Itoi T

更新日期：2015-09-01 00:00:00

abstract：:Progressive familial intrahepatic cholestasis (PFIC) syndromes are characterized by defects in transporters of conjugated bile acids into the bile canaliculus. Three genes (ATP8B1, ABCB11, ABCB4) are associated with the different forms, but no easy genotype-phenotype correlations help in the prioritization for gene te...

journal_title：Journal of gastroenterology

authors： Nobili V,Di Giandomenico S,Francalanci P,Callea F,Marcellini M,Santorelli FM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Ursodeoxycholic acid (UDCA) partly exerts choleretic effects by modifying the function of the bile salt export pump (Bsep, ABCB11). UDCA induces insertion of Bsep into the canalicular membrane of hepatocytes; however, underlying mechanisms remain unknown. We aimed to elucidate molecular mechanisms behind UDC...

journal_title：Journal of gastroenterology

authors： Kagawa T,Orii R,Hirose S,Arase Y,Shiraishi K,Mizutani A,Tsukamoto H,Mine T

更新日期：2014-05-01 00:00:00

abstract：:Various types of polyunsaturated fatty acids (PUFAs) have been suggested to exert different effects on the colon in terms of promotion or inhibition of tumor development. Results of in vitro and in vivo studies are, however, inconsistent and it remains unclear whether or not the cellular effects of PUFAs change along ...

journal_title：Journal of gastroenterology

authors： Tsai WS,Nagawa H,Kaizaki S,Tsuruo T,Muto T

更新日期：1998-04-01 00:00:00

abstract：:We report two cirrhotic patients with gastric antral vascular ectasia (GAVE) in whom chronic blood loss presented a major problem. Case 1, a 69-year-old man, had alcoholic liver cirrhosis, and case 2, a 75-year-old woman, had liver cirrhosis associated with hepatitis C virus. The patients required repeated blood trans...

journal_title：Journal of gastroenterology

authors： Yamada M,Nishimura D,Hoshino H,Katada N,Sano H,Kato K

更新日期：1998-08-01 00:00:00

abstract：:We report a case of synchronous gas gangrene and spontaneous bacterial peritonitis associated with liver cirrhosis. The patient was a 52-year-old man who was being followed for decompensated liver cirrhosis. He experienced sudden onset lower abdominal pain with distension and pain in the left leg. A bullous lesion, wi...

journal_title：Journal of gastroenterology

authors： Murata K,Shimizu A,Takase K,Nakano T,Tameda Y

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Several small, prospective, open studies suggest that leukocytapheresis might be efficient in patients with steroid-dependent ulcerative colitis (UC). AIM:To evaluate the short- and long-term effectiveness of leukocytapheresis for the management of steroid-dependent UC in clinical practice. METHODS:A Web-b...

journal_title：Journal of gastroenterology

authors： Cabriada JL,Domènech E,Ibargoyen N,Hernández V,Clofent J,Ginard D,Gutiérrez-Ibarluzea I,Hinojosa J

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The dynamic change in gastric emptying on a minute-by-minute basis (gastric velocity) is evaluated by the 13C-octanoate breath test with deconvolution analysis. However, deconvolution is impractical, because it requires dual experiments to obtain 13CO2 excretion profiles following intraduodenal and oral admi...

journal_title：Journal of gastroenterology

authors： Sanaka M,Yamamoto T,Osaki Y,Kuyama Y

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The ideal medication for the treatment of acid-related diseases, for example, hemorrhagic ulcers and stress-related gastric bleeding, should have a rapid onset of action to promote hemostasis and alleviate symptoms. The aim of our study was to investigate the inhibitory effects on gastric acid secretion afte...

journal_title：Journal of gastroenterology

authors： Abe Y,Inamori M,Togawa J,Kikuchi T,Muramatsu K,Chiguchi G,Kawamura H,Kobayashi N,Kirikoshi H,Sakaguchi T,Takamura T,Nakajima A,Ueno N,Sekihara H

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) are one of the major classes of proteolytic enzymes involved in tumor invasion and metastasis, being inhibited by naturally occurring tissue inhibitors of metalloproteinases (TIMPs). In this study, we examined the expression of MMP-2, MMP-9, membrane-type 1 (MT1)-MMP, TIMP-1,...

journal_title：Journal of gastroenterology

authors： Shim KN,Jung SA,Joo YH,Yoo K

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The transcription factor nuclear factor-E2-related factor-2 (Nrf2) inhibits lipid accumulation and oxidative stress in the liver by interfering with lipogenic pathways and inducing antioxidative stress genes. METHODS:The involvement of Nrf2 in defense against the development of steatohepatitis was studied i...

journal_title：Journal of gastroenterology

authors： Okada K,Warabi E,Sugimoto H,Horie M,Gotoh N,Tokushige K,Hashimoto E,Utsunomiya H,Takahashi H,Ishii T,Yamamoto M,Shoda J

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) is characterized by chronic inflammation in the colon and epigenetic factors underlying the occurrence. Circular RNAs (circRNAs) have been under intensive focus due to the circular construct and gene-regulating functions. However, the changes and roles of circRNAs in UC remain unknown...

journal_title：Journal of gastroenterology

authors： Wang T,Chen N,Ren W,Liu F,Gao F,Ye L,Han Y,Zhang Y,Liu Y

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) core protein is known to cause oxidative stress and alter apoptosis pathways. However, the apoptosis results are inconsistent, and the real significance of oxidative stress is not well known. The aim of this study was twofold. First, we wanted to confirm whether core-induced oxidative...

journal_title：Journal of gastroenterology

authors： Hara Y,Hino K,Okuda M,Furutani T,Hidaka I,Yamaguchi Y,Korenaga M,Li K,Weinman SA,Lemon SM,Okita K

更新日期：2006-03-01 00:00:00

abstract：:Anomalous arrangement of the pancreaticobiliary ductal system (AAPB), a congenital anomaly defined as a union of the pancreatic and biliary ducts located outside the duodenal wall, is a newly designated disease entity, and is frequently found in adult patients with gallbladder carcinoma (GBX). In the present study, th...

journal_title：Journal of gastroenterology

authors： Yang Y,Fujii H,Matsumoto Y,Suzuki K,Kawaoi A,Suda K

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Although it is less frequently encountered, mesenteric vein occlusion poses as important a problem as mesenteric artery occlusion. The energy metabolism of intestinal tissue during venous occlusion and reperfusion was studied. METHODS:Male Wistar rats were studied in four groups of 17 animals each. Intestin...

journal_title：Journal of gastroenterology

authors： Kimura M,Kataoka M,Kuwabara Y,Sato A,Sugiura M,Fujii Y

更新日期：2003-01-01 00:00:00

abstract：:The incidence and prevalence of primary biliary cirrhosis show wide geographic differences. The frequency of this disease in Japan is lower than in Northern Europe. To elucidate the immunoreactivity of serum with enzymes of the 2-oxo-acid dehydrogenase complex (2-OADC) and the M2 mitochondrial antigenic complex in Jap...

journal_title：Journal of gastroenterology

authors： Omagari K,Rowley MJ,Jois JA,Feeney SJ,Komatsu K,Maeda T,Onishi S,Yamazaki K,Suzuki K,Galperin C,Mackay IR

更新日期：1996-02-01 00:00:00

abstract：:In our hospital, 83 patients with colorectal cancer underwent the immunologic fecal occult blood test (IFOBT). The positive rate for IFOBT in all patients was 87%. Colon cancers more proximal than the transverse colon were 100% positive. Carcinomas of the ulcerative type showed a significantly higher positive rate tha...

journal_title：Journal of gastroenterology

authors： Iida Y,Munemoto Y,Miura S,Kasahara Y,Saito H,Mitsui T,Asada Y,Fukuoka K,Toya D,Tanaka N

更新日期：1995-04-01 00:00:00

abstract：:An association of hidradenitis suppurativa with Crohn's disease is supported by previous repent. We here report a patient with hidradenitis suppurativa who subsequently developed peripheral arthritis, sacroiliitis, and Crohn's disease. A significant attenuation of bowel, cutaneous, and joint symptoms was achieved afte...

journal_title：Journal of gastroenterology

authors： Roussomoustakaki M,Dimoulios P,Chatzicostas C,Kritikos HD,Romanos J,Panayiotides JG,Kouroumalis EA

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Most studies evaluating visceral sensation measure visceromotor response (VMR) to colorectal distention (CRD). However, CRD itself induces visceral sensitization, and little is known about the detailed characteristics of this response. The present study tried to clarify this question. METHODS:VMR was determ...

journal_title：Journal of gastroenterology

authors： Nozu T,Kumei S,Miyagishi S,Takakusaki K,Okumura T

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The p53 tumor suppressor protein plays a fundamental role in maintaining genomic integrity through its ability to arrest the cell cycle in G1 and induce apoptosis. The proapoptotic activity of p53 seems to be strictly related to proline-rich regions, homologous to the SH3 binding domain. In the literature, r...

journal_title：Journal of gastroenterology

authors： Vietri MT,Riegler G,Ursillo A,Caserta L,Cioffi M,Molinari AM

更新日期：2007-06-01 00:00:00