Hidradenitis suppurativa associated with Crohn's disease and spondyloarthropathy: response to anti-TNF therapy.

abstract：:Asia has intermediate-to-high prevalence and high morbidity of hepatitis B virus (HBV) infection. The use of guideline-recommended nucleos(t)ide analogs with high barrier to resistance, such as entecavir (ETV), tenofovir disoproxil fumarate (TDF), and tenofovir alafenamide (TAF), is one of the key interventions for cu...

journal_title：Journal of gastroenterology

authors： Charlton MR,Alam A,Shukla A,Dashtseren B,Lesmana CRA,Duger D,Payawal DA,Duy Cuong D,Jargalsaikhan G,Cua IHY,Sollano JD,Singh KR,Madan K,Win KM,Kyi KP,Tun KS,Salih M,Rastogi M,Saraf N,Thuy PTT,Hien PTD,Gani RA,

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:An optimal surveillance program is important to prevent advanced colorectal neoplasm. In this context, we have evaluated the cumulative risk of high-risk adenoma (HRA) or colorectal cancer (CRC) according to surveillance interval time after polypectomy. In addition, we assessed risk factors for late surveill...

journal_title：Journal of gastroenterology

authors： Tae CH,Moon CM,Kim SE,Jung SA,Eun CS,Park JJ,Seo GS,Cha JM,Park SC,Chun J,Lee HJ,Jung Y,Kim JO,Joo YE,Park DI

更新日期：2017-07-01 00:00:00

abstract：:Endoscopic surveillance of Barrett's esophagus has become a foundation of the management of esophageal adenocarcinoma (EAC). Surveillance for Barrett's esophagus commonly involves periodic upper endoscopy with biopsies of suspicious areas and random four-quadrant biopsies. However, targeted biopsies using narrow-band ...

journal_title：Journal of gastroenterology

authors： Ishihara R,Goda K,Oyama T

更新日期：2019-01-01 00:00:00

abstract：:Class II antigens are strongly expressed on the inflamed colonic epithelium in inflammatory bowel disease. However, the mechanism of this epithelial class II antigen induction is not fully understood. Increased activities of interferon (IFN)gamma, tumor necrosis factor (TNF)alpha, and interleukin (IL)2 have been shown...

journal_title：Journal of gastroenterology

authors： Horie Y,Chiba M,Suzuki T,Kudo T,Kamata A,Iizuka M,Masamune O

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Angiogenesis is essential for gastric ulcer healing. Recent results suggest that vascular endothelial growth factor receptor 1 (VEGFR1), which binds to VEGF, promotes angiogenesis. In the present study, we investigated the role of VEGFR1 signaling in gastric ulcer healing and angiogenesis. METHODS:Gastric u...

journal_title：Journal of gastroenterology

authors： Sato T,Amano H,Ito Y,Eshima K,Minamino T,Ae T,Katada C,Ohno T,Hosono K,Suzuki T,Shibuya M,Koizumi W,Majima M

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The most commonly used methods for bowel preparation are polyethylene glycol-electrolyte lavage solution (PEG-ELS) and sodium phosphate. Both are problematic in children. The use of bisacodyl together with fleet enema has been suggested as an alternative; however, its use without dietary restriction is infer...

journal_title：Journal of gastroenterology

authors： Shaoul R,Haloon L

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Insulin-like growth factor (IGF)-I receptor (IGF-IR) signaling plays important parts in both the tumorigenicity and progression of digestive/gastrointestinal malignancies. In this study, we sought to test the effectiveness of a practical approach to blocking IGF-IR signaling using RNA interference d...

journal_title：Journal of gastroenterology

authors： Wang Y,Adachi Y,Imsumran A,Yamamoto H,Piao W,Li H,Ii M,Arimura Y,Park MY,Kim D,Lee CT,Carbone DP,Imai K,Shinomura Y

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Dual oral therapy with daclatasvir plus asunaprevir yielded an SVR rate of 85% among patients with genotype 1b HCV. Treatment failure mainly occurred in patients with pre-existing HCV with NS5A-Y93H mutation. The significance of the mutation was evaluated. METHODS:The percent of serum NS5A-Y93H strains rela...

journal_title：Journal of gastroenterology

authors： Uchida Y,Kouyama J,Naiki K,Sugawara K,Ando S,Nakao M,Motoya D,Inao M,Imai Y,Nakayama N,Mochida S

更新日期：2016-03-01 00:00:00

abstract：:We investigated the therapeutic effects of egualen sodium (KT1-32), a new antiulcer agent, on chronic erosive and atrophic gastritis induced by 5 months' administration of sodium taurocholate (TCA; 5 mM) in rats. The chronic gastritis was manifested by mucosal surface injuries (erosions), reduced mucosal thickness, re...

journal_title：Journal of gastroenterology

authors： Mochizuki S,Matsumoto M,Wakabayashi S,Kosakai K,Tomiyama A,Kishimoto S

更新日期：1996-12-01 00:00:00

abstract：:Focal nodular hyperplasia (FNH) is a benign lesion of the liver which usually presents with one or two localizations. We report a patient with history of resection of a biliary cyst, and who had been taking oral contraceptives for the past 18 years, who had multiple localizations of FNH (more than 30 lesions). The lar...

journal_title：Journal of gastroenterology

authors： Colle I,de Beeck BO,Hoorens A,Hautekeete M

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Patients with ulcerative colitis (UC) exhibit overproduction of reactive oxygen species (ROS) and imbalance of colonic microflora. We previously developed a novel redox nanoparticle (RNP(O)), which effectively scavenged ROS in the inflamed mucosa of mice with dextran sodium sulfate (DSS)-induced colitis afte...

journal_title：Journal of gastroenterology

authors： Vong LB,Yoshitomi T,Morikawa K,Saito S,Matsui H,Nagasaki Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Recently, a significant relationship between gastric cancer and Helicobacter pylori infection has been proven. The purpose of this study was to elucidate the actual conditions of H. pylori infection in Japanese teenagers. METHODS:The study subjects were students at a certain high school between 2007 and 200...

journal_title：Journal of gastroenterology

authors： Akamatsu T,Ichikawa S,Okudaira S,Yokosawa S,Iwaya Y,Suga T,Ota H,Tanaka E

更新日期：2011-12-01 00:00:00

abstract：:Focal nodular hyperplasia (FNH) of the liver is a rare benign lesion that probably reflects a local hyperplastic response of hepatocytes to a vascular abnormality. Currently, the natural history of the disease remains largely unknown. We present a patient with FNH of the liver who was followed up for 4 years. A 22-yea...

journal_title：Journal of gastroenterology

authors： Ohmoto K,Honda T,Hirokawa M,Mitsui Y,Iguchi Y,Kuboki M,Yamamoto S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) is characterized by chronic inflammation in the colon and epigenetic factors underlying the occurrence. Circular RNAs (circRNAs) have been under intensive focus due to the circular construct and gene-regulating functions. However, the changes and roles of circRNAs in UC remain unknown...

journal_title：Journal of gastroenterology

authors： Wang T,Chen N,Ren W,Liu F,Gao F,Ye L,Han Y,Zhang Y,Liu Y

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:It is controversial whether patients with gastric marginal zone lymphomas of mucosa associated lymphoid tissue (MALT) have higher risk of second malignancies. The aim of this study was to define the risk of second malignancies in these patients. METHODS:We analyzed prospective follow-up data of 146 consecut...

journal_title：Journal of gastroenterology

authors： Tajika M,Matsuo K,Ito H,Chihara D,Bhatia V,Kondo S,Tanaka T,Mizuno N,Hara K,Hijioka S,Imaoka H,Matsumoto K,Nakamura T,Yatabe Y,Yamao K,Niwa Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The apelin receptor (APJ) is related to angiotensin-like-receptor 1 (AGTRL1). This study was designed to elucidate the in vivo localization and changes of APJ in cirrhotic liver, and the in vitro changes of APJ expression in cultured hepatic stellate cells (HSCs) and capillarized sinusoidal endothelial cells...

journal_title：Journal of gastroenterology

authors： Yokomori H,Oda M,Yoshimura K,Machida S,Kaneko F,Hibi T

更新日期：2011-02-01 00:00:00

abstract：:Soft drinks containing dietary fiber are popular in Japan. There seem to be two types, one containing polydextrose and the other, oligosaccharide. These beverages are claimed to be useful for constipation or obesity, but data are scanty. We examined four such fiber-containing beverages [Fibe-mini Otsuka Pharmaceutical...

journal_title：Journal of gastroenterology

authors： Kondo T,Nakae Y

更新日期：1996-10-01 00:00:00

abstract：:Cholecystokinin (CCK) receptor antagonists have been reported on have an inhibitory effect on acute experimental pancreatitis, but their long-term administration is also reported to block pancreatic regeneration. We examined whether the short-term administration of KSG-504 (KSG), a synthetic CCK-A receptor antagonist,...

journal_title：Journal of gastroenterology

authors： Okumura Y,Inoue H,Fujiyama Y,Bamba T

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) consists of nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH); the latter progresses to liver cirrhosis and hepatocellular carcinoma. Discriminating NASH from NAFL typically involves liver biopsy. The mechanism of NASH progression is unclear but ...

journal_title：Journal of gastroenterology

authors： Kado A,Tsutsumi T,Enooku K,Fujinaga H,Ikeuchi K,Okushin K,Moriya K,Yotsuyanagi H,Koike K

更新日期：2019-08-01 00:00:00

abstract：:We present herein a case of a 75-year-old Japanese man who had developed a pancreatic abscess 7 years after a longitudinal pancreatojejunostomy for chronic pancreatitis. The patient, a heavy drinker of alcohol, underwent surgical decompression of a ductal obstruction to relieve persistent abdominal pain due to severel...

journal_title：Journal of gastroenterology

authors： Suzuki A,Matsunaga T,Aoki S,Hirayama T,Nakagawa N,Shibata K,Yabana T,Kawasaki H,Takasaka H,Sasaki K,Katsuramaki T,Mukaiya M,Hirata K,Imai K

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:In patients chronically infected with hepatitis B virus, interferon has been used for the purpose of viral suppression by loss of hepatitis B e antigen (HBeAg) with or without seroconversion to antibody to HBeAg (anti-HBe). However, discussion about the effect of interferon on the development of hepatocellular ...

journal_title：Journal of gastroenterology

authors： Miyake Y,Kobashi H,Yamamoto K

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Abrogating tolerance is a critical step in the pathogenesis of Crohn's disease (CD). T cell-anergy is one of the main mechanisms of tolerance and is regulated by the gene related to anergy in lymphocytes (GRAIL). This study investigated the expressions and regulation of GRAIL in CD and murine colitis models....

journal_title：Journal of gastroenterology

authors： Mukai A,Iijima H,Hiyama S,Fujii H,Shinzaki S,Inoue T,Shiraishi E,Kawai S,Araki M,Hayashi Y,Kondo J,Mizushima T,Kanto T,Egawa S,Nishida T,Tsujii M,Takehara T

更新日期：2014-12-01 00:00:00

abstract：:Perianal fistulae are frequently seen complications in Crohn's disease. Although surgical procedures such as Seton's method have been devised, many patients still suffer from fistulae that are resistant to conventional therapy. We administered oral adsorbent to a patient with disease Crohn's who had a complicated peri...

journal_title：Journal of gastroenterology

authors： Tsujikawa T,Araki Y,Makino J,Uda K,Ihara T,Sasaki M,Fujiyama Y,Bamba T

更新日期：2000-01-01 00:00:00

abstract：:A new triple therapy using a proton pump inhibitor and two antibiotics shows high efficiency against Helicobacter pylori infection. The aim of this study was to determine the optimal dose and duration of lansoprazole (LA) administration in combination with amoxicillin (AMPC) and metronidazole (MNZ). A total of 91 pati...

journal_title：Journal of gastroenterology

authors： Nishikawa K,Sugiyama T,Ishizuka J,Kudo T,Komatsu Y,Katagiri M,Sukegawa M,Kagaya H,Kudo M,Kato M,Takeda H,Toyota J,Asaka M

更新日期：1999-01-01 00:00:00

abstract：:Cancer is caused by the accumulation of inherited and/or acquired alterations in specific genes. The recent decline in the cost of DNA sequencing has allowed tumor sequencing to be conducted on a large scale, which, in turn, has led to an unprecedented understanding of the genetic events that drive neoplasia. This und...

journal_title：Journal of gastroenterology

authors： Matthaei H,Semaan A,Hruban RH

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:In elderly patients with superficial esophageal squamous cell carcinoma (ESCC), the optimal treatment strategy after non-curative endoscopic submucosal dissection (ESD) remains unclear. We aimed to evaluate the validity of additional treatments after non-curative ESD and post-ESD survival predictors in elder...

journal_title：Journal of gastroenterology

authors： Nakajo K,Abe S,Oda I,Ishihara R,Tanaka M,Yoshio T,Katada C,Yano T

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Although colorectal cancer (CRC) is one of the most common causes of cancer mortality, early-stage detection improves survival rates dramatically. Because cancer impacts important metabolic pathways, the alteration of metabolite levels as a potential biomarker of early-stage cancer has been the focus of many...

journal_title：Journal of gastroenterology

authors： Uchiyama K,Yagi N,Mizushima K,Higashimura Y,Hirai Y,Okayama T,Yoshida N,Katada K,Kamada K,Handa O,Ishikawa T,Takagi T,Konishi H,Kuriu Y,Nakanishi M,Otsuji E,Itoh Y,Naito Y

更新日期：2017-06-01 00:00:00

abstract：:A 21-year-old man with diarrhea and edema was admitted to our hospital and diagnosed with protein-losing enteropathy caused by primary intestinal lymphangiectasia. He was placed, in turn, on a low-fat diet, an elemental diet, and, subsequently, fasting therapy with total parenteral nutrition (TPN) support. However, hi...

journal_title：Journal of gastroenterology

authors： Kuroiwa G,Takayama T,Sato Y,Takahashi Y,Fujita T,Nobuoka A,Kukitsu T,Kato J,Sakamaki S,Niitsu Y

更新日期：2001-02-01 00:00:00

abstract：:Gastric mucosal lesions are an important complication in endotoxemia. In order to define the role played by the vagus nerve and endothelial-derived relaxing factor (EDRF) in gastric mucosal blood flow, an investigation was carried out on four groups of rats: a control group; a group given lipopolysaccharide (LPS, 5 mg...

journal_title：Journal of gastroenterology

authors： Sakano T,Itoh K,Tanaka M,Arakawa Y,Matsuo Y

更新日期：1995-02-01 00:00:00

abstract：:Cytosolic phospholipase A2 (PLase A2) is activated by low Ca2+ concentrations and translocates from the cytosol to the cell membrane, releasing arachidonic acid; the arachidonic acid cascade then leads to the production of many inflammatory mediators. The aim of this study, accordingly, was to investigate the role of ...

journal_title：Journal of gastroenterology

authors： Morita H,Nakanishi K,Dohi T,Yasugi E,Oshima M

更新日期：1999-02-01 00:00:00