Efficacy of oral adsorbent for treatment of peristomal fistula associated with Crohn's disease.

Abstract:

:Perianal fistulae are frequently seen complications in Crohn's disease. Although surgical procedures such as Seton's method have been devised, many patients still suffer from fistulae that are resistant to conventional therapy. We administered oral adsorbent to a patient with disease Crohn's who had a complicated peristomal fistula that did not improve with conventional therapy. Six grams of oral adsorbent (AST-120) were added daily to a regimen of elemental diet therapy and prednisolone. The fistula gradually decreased in size after the administration of the oral adsorbent, and had healed completely after 40 days' treatment. There were no side effects from the oral adsorbent. This case report suggests that oral adsorbent is an effective treatment for peristomal fistula associated with Crohn's disease.

journal_name

J Gastroenterol

authors

Tsujikawa T,Araki Y,Makino J,Uda K,Ihara T,Sasaki M,Fujiyama Y,Bamba T

doi

10.1007/s005350050349

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

296-8

issue

4

eissn

0944-1174

issn

1435-5922

journal_volume

35

pub_type

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