Abstract:
:Although esophageal candidiasis is the most common form of Candida infection in the gastro-intestinal tract, little attention has been directed toward determining the mechanism of its infection. We have already clarified the existence of four modes of adherence of Candida albicans to the esophagus; attachment, subepithelial cell insertion, cavitation, and invasion. This study was undertaken to clarify the significance of each of these modes. Scanning electron microscopic observations were made of esophageal specimens from 8-week-old rabbits infected with Candida albicans IFO 1060. In this study, attachment and subepithelial cell insertion were found to be the most frequent modes of adherence. Cavitation occurred following subepithelial cell insertion, while invasion occurred following attachment and subepithelial cell insertion. These results suggest that attachment and subepithelial cell insertion play the most important role in the initial stage of adherence. The ratios of these modes for living yeast cells were similar to those for dead yeast cells and beads. This suggests that Candida albicans can gain a foothold on the esophageal epithelium solely by physical contact, after which colonization occurs.
journal_name
J Gastroenteroljournal_title
Journal of gastroenterologyauthors
Hoshika K,Mine Hdoi
10.1007/BF01229065subject
Has Abstractpub_date
1994-02-01 00:00:00pages
1-5issue
1eissn
0944-1174issn
1435-5922journal_volume
29pub_type
杂志文章abstract:BACKGROUND:Neovascularization was shown to be critically involved in the progression of multiple cancers, and treatment approaches targeting tumor-associated neovascularization provide convincing results in recent years in some tumor entities. However, little is known about the tumor-associated neovascularization in hi...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-008-2255-9
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:The purpose of our study was to evaluate the long-term outcome and complications of balloon-occluded retrograde transvenous obliteration (B-RTO) in patients with hemorrhage from gastric fundal varices. METHODS:Thirty-four consecutive patients with bleeding from gastric varices who were treated with B-RTO we...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-007-2077-1
更新日期:2007-08-01 00:00:00
abstract::Progressive familial intrahepatic cholestasis (PFIC) syndromes are characterized by defects in transporters of conjugated bile acids into the bile canaliculus. Three genes (ATP8B1, ABCB11, ABCB4) are associated with the different forms, but no easy genotype-phenotype correlations help in the prioritization for gene te...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-006-1816-z
更新日期:2006-06-01 00:00:00
abstract::Chronic inflammatory bowel disease (IBD) is an important etiologic factor in the development of colorectal cancer. However, the mechanism underlying the development of colorectal cancers through chronic inflammation is not known. Activation-induced cytidine deaminase (AID) was originally identified as an inducer of so...
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pub_type: 杂志文章
doi:10.1007/s00535-010-0326-1
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:We recently reported the efficacy of indigo naturalis (IN) in patients with active ulcerative colitis (UC) in a randomized controlled trial (INDIGO study). However, few studies have been conducted to investigate whether IN is effective even in treatment-refractory cases, such as in those with steroid depende...
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pub_type: 杂志文章
doi:10.1007/s00535-019-01625-2
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:It remains unknown whether the Rome III criteria can exclude organic colonic lesions prior to the diagnosis of irritable bowel syndrome (IBS). We evaluated the colonoscopy results of patients meeting the Rome III criteria for the diagnosis of IBS to determine the presence of organic colonic lesions. METHODS...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00535-012-0573-4
更新日期:2012-10-01 00:00:00
abstract::A 69-year-old woman was admitted to Hokuso Shiroi Hospital because of recurrent pain in the lower right side of the abdomen. Small-intestinal cancer was strongly suspected after fluoroscopy of the small intestine. Laparotomy showed advanced cancer of the ileum, of complete annular constrictive type, 9.5 x 5cm in size....
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s005350050102
更新日期:1998-06-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-012-0722-9
更新日期:2013-09-01 00:00:00
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journal_title:Journal of gastroenterology
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更新日期:2001-02-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-015-1117-5
更新日期:2016-04-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/BF02990103
更新日期:2002-01-01 00:00:00
abstract::The chemotactic activity of Helicobacter pylori is important for its colonization. H. pylori exhibited chemotactic responses to urea and potassium bicarbonate, which can be supplied from human gastric epithelium. The chemotactic activities of H. pylori in a fluid environment were higher on the urease-positive strain t...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Three-dimensional-computed tomography (3D-CT) cholangiography is a 3D shaded surface display image of the biliary tract obtained by using helical CT after intravenous cholangiography or cholangiography per percutaneous transhepatic cholangio-drainage tube. We investigated whether 3D-CT cholangiography could provide a ...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s005350050225
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:The introduction of capsule endoscopy (CE) has facilitated the detection of mucosal changes in the small bowel, and such mucosal changes have been noted in cirrhotic patients with portal hypertension; these changes are described as portal hypertensive enteropathy. The aim of this study was to assess the effe...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-012-0660-6
更新日期:2013-05-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02361248
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:At present, squamous cell carcinoma accounts for most esophageal cancers in Japan; however, there is concern that the incidence of esophageal adenocarcinoma in Japan is increasing in comparison to Western countries. Akita Prefecture, with a population of 1 million, has the highest rate of esophageal cancer-a...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-017-1412-4
更新日期:2018-07-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-015-1058-z
更新日期:2015-11-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/BF02355069
更新日期:1996-08-01 00:00:00
abstract::Nonrotation of the midgut in adults and appendiceal mucocele are both rare pathological conditions. We report here the first case of nonrotation of the midgut associated with appendiceal mucocele. The patient was a 51-year-old man admitted to hospital with ileus. An upper gastrointestinal series and a barium enema rev...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s005350170153
更新日期:2001-01-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.1007/s005350200000
更新日期:2002-01-01 00:00:00
abstract::The correct name of the last author should be. ...
journal_title:Journal of gastroenterology
pub_type: 已发布勘误
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更新日期:2020-01-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/BF02358371
更新日期:1994-06-01 00:00:00
abstract::Using commercial quantitative assays, quantitative hepatitis B surface antigen (qHBsAg) has improved our understanding and management of chronic hepatitis B (CHB). The HBsAg level is highest in the immune tolerance phase, starts to decline during the immune clearance phase, and decreases slowly but progressively after...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:In the respiratory mucosa, interleukin (IL)-33, has been shown to enhance T helper 2 (TH2)-type responses through the master regulatory gene GATA-3. IL-33 is upregulated in ulcerative colitis (UC), and the aim was to assess if IL-33 holds a similar key position in the shaping of the immune response in experi...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-014-0982-7
更新日期:2015-02-01 00:00:00
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journal_title:Journal of gastroenterology
pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Adiponectin has been shown to have suppressive effects on tumor development, but the expression of adiponectin receptors in tumor tissue has not been fully elucidated. The purpose of this study was to quantitatively evaluate the expression of two adiponectin receptors, AdipoR1 and AdipoR2, in gastric cancer ...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-010-0228-2
更新日期:2010-09-01 00:00:00
abstract::Cold restraint stress (CRS) induced vagal-dependent corpus mucosal erosions with hemorrhage in rats. Aggressive factors such as gastric acid, pepsin, and high-amplitude contractions have been reported to be responsible for inducing the formation of gastric lesions. Thyrotropin-releasing hormone (TRH) microinjected int...
journal_title:Journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.1007/BF03326431
更新日期:2002-11-01 00:00:00
abstract::Although anemia is one of the signs of colorectal cancer, the relationships between histological findings and hematological findings other than hemoglobin level have not been adequately investigated. We investigated the relationship between hematological findings, serum iron, and histological findings in 358 patients ...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s005350050120
更新日期:1998-08-01 00:00:00
abstract:PURPOSE:Hepatic steatosis is frequently observed in subjects with metabolic syndrome (MS). In type 2 diabetics, it is independently associated with cardiovascular diseases. In order to confirm and extend this finding, a large group of patients with risk factors for atherosclerosis was studied. METHODS:Carotid atherosc...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
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更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:There have only been a few prospective studies investigating risk factors associated with the development of hepatocellular carcinoma (HCC) among chronic hepatitis B patients all over the world, and no study has been conducted in Japanese population. METHODS:A population-based cohort consisting of 19393 sub...
journal_title:Journal of gastroenterology
pub_type: 杂志文章
doi:10.1007/s00535-010-0307-4
更新日期:2011-01-01 00:00:00