Current status of preoperative biliary drainage.

abstract：:An expert meeting was organized by the Swedish and Norwegian Medical Products Agencies in September 1995 in order to review the current literature and opinions on detection and treatment of Helicobacter pylori. Ten people from these Agencies and 23 experts participated in the workshop and all were involved in the fina...

journal_title：Journal of gastroenterology

authors： Unge P

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Little is known about the difference in enhancement patterns of hepatocellular carcinoma (HCC) during multistep hepatocarcinogenesis between the post-vascular phase of Sonazoid-enhanced ultrasonography (SEUS) and hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriamine (Gd-EOB-DTPA)-enhanced MRI, as...

journal_title：Journal of gastroenterology

authors： Ohama H,Imai Y,Nakashima O,Kogita S,Takamura M,Hori M,Seki Y,Sawai Y,Igura T,Fukuda K,Makino Y,Morimoto O,Ohsawa M,Sakamoto M,Murakami T

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND AIM:Mac-2 Binding Protein Glycosylation Isomer (M2BPGi) is a novel fibrosis marker. We examined the ability of M2BPGi to predict liver fibrosis in patients with biliary atresia. METHODS:Sixty-four patients who underwent living donor liver transplantation (LDLT) were included [median age, 1.1 years (rang...

journal_title：Journal of gastroenterology

authors： Yamada N,Sanada Y,Tashiro M,Hirata Y,Okada N,Ihara Y,Urahashi T,Mizuta K

更新日期：2017-02-01 00:00:00

abstract：:As an increase in gastroesophageal reflux disease (GERD) has been reported in Japan, and public interest in GERD has been increasing, the Japanese Society of Gastroenterology published the Evidence-based Clinical Practice Guidelines for GERD (1st edition) in 2009. Six years have passed since its publication, and there...

journal_title：Journal of gastroenterology

authors： Iwakiri K,Kinoshita Y,Habu Y,Oshima T,Manabe N,Fujiwara Y,Nagahara A,Kawamura O,Iwakiri R,Ozawa S,Ashida K,Ohara S,Kashiwagi H,Adachi K,Higuchi K,Miwa H,Fujimoto K,Kusano M,Hoshihara Y,Kawano T,Haruma K,Hongo M

更新日期：2016-08-01 00:00:00

abstract：:Focal nodular hyperplasia (FNH) of the liver is a rare benign lesion that probably reflects a local hyperplastic response of hepatocytes to a vascular abnormality. Currently, the natural history of the disease remains largely unknown. We present a patient with FNH of the liver who was followed up for 4 years. A 22-yea...

journal_title：Journal of gastroenterology

authors： Ohmoto K,Honda T,Hirokawa M,Mitsui Y,Iguchi Y,Kuboki M,Yamamoto S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Hypersensitive esophagus (HE) is defined by endoscopy-negative heartburn with a normal acid exposure time but positive symptom association probability (SAP) and/or symptom index (SI) on impedance-pH monitoring, and proton pump inhibitor (PPI) responsiveness. Functional heartburn (FH) is distinguished by nega...

journal_title：Journal of gastroenterology

authors： Frazzoni M,de Bortoli N,Frazzoni L,Furnari M,Martinucci I,Tolone S,Farioli A,Marchi S,Fuccio L,Savarino V,Savarino E

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Cold snare polypectomy (CSP) has not undergone sufficient histopathological evaluation. This study aimed to clarify the histopathological features of CSP specimens, including resection depth and layer, as compared with endoscopic mucosal resection (EMR). METHODS:Polyps were recruited retrospectively. Sessil...

journal_title：Journal of gastroenterology

authors： Ito A,Suga T,Ota H,Tateiwa N,Matsumoto A,Tanaka E

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:As biopsy sites may miss coexisting gastric mucosal high grade neoplasia (HGN) foci, making a diagnosis of gastric mucosal low grade neoplasia (LGN) based only on forceps biopsy specimens can be inaccurate. Therefore, to achieve an accurate diagnosis, endoscopic mucosal resection (EMR) of the entire lesion i...

journal_title：Journal of gastroenterology

authors： Min BH,Kim KM,Kim ER,Park CK,Kim JJ,Lee H,Lee JH,Chang DK,Kim YH,Rhee PL,Rhee JC

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Although colorectal cancer (CRC) is one of the most common causes of cancer mortality, early-stage detection improves survival rates dramatically. Because cancer impacts important metabolic pathways, the alteration of metabolite levels as a potential biomarker of early-stage cancer has been the focus of many...

journal_title：Journal of gastroenterology

authors： Uchiyama K,Yagi N,Mizushima K,Higashimura Y,Hirai Y,Okayama T,Yoshida N,Katada K,Kamada K,Handa O,Ishikawa T,Takagi T,Konishi H,Kuriu Y,Nakanishi M,Otsuji E,Itoh Y,Naito Y

更新日期：2017-06-01 00:00:00

abstract：:We used positron emission tomography with 2-deoxy-2-[(18)F]fluoro- d-glucose (FDG-PET) in the diagnosis of two cases of malignant intraductal papillary mucinous tumor (IPMT) of the pancreas. A 56-year-old man and a 72-year-old man, both with tumors in the pancreatic head, were referred to Akita University Medical Cent...

journal_title：Journal of gastroenterology

authors： Yoshioka M,Sato T,Furuya T,Shibata S,Andoh H,Asanuma Y,Hatazawa J,Koyama K

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Loss of imprinting (LOI) of the insulin-like growth factor 2 (IGF2) is an early event in the development of colorectal cancer (CRC). Whether LOI of IGF2 denotes a molecular or clinical cancer subgroup is currently unknown. METHODS:Tumor biopsies and paired normal mucosa from 399 patients with extensive clin...

journal_title：Journal of gastroenterology

authors： Belharazem D,Magdeburg J,Berton AK,Beissbarth L,Sauer C,Sticht C,Marx A,Hofheinz R,Post S,Kienle P,Ströbel P

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Liver histology is the gold standard for the diagnosis of nonalcoholic steatohepatitis (NASH). Noninvasive, simple, reproducible, and reliable biomarkers are greatly needed to differentiate NASH from nonalcoholic fatty liver disease (NAFLD). METHODS:To construct a scoring system for predicting NASH, 177 Jap...

journal_title：Journal of gastroenterology

authors： Sumida Y,Yoneda M,Hyogo H,Yamaguchi K,Ono M,Fujii H,Eguchi Y,Suzuki Y,Imai S,Kanemasa K,Fujita K,Chayama K,Yasui K,Saibara T,Kawada N,Fujimoto K,Kohgo Y,Okanoue T,Japan Study Group of Nonalcoholic Fatty Liver Disease

更新日期：2011-02-01 00:00:00

abstract：:We investigated whether extravariceal collateral pattern contributed to the development of portal-hypertensive gastropathy (PHG) before and after sclerotherapy. Ninety-nine patients with cirrhosis and large esophageal varices were examined in this retrospective study. They were divided into four groups according to tr...

journal_title：Journal of gastroenterology

authors： Nakayama M,Iwao T,Oho K,Toyonaga A,Tanikawa K

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:In acute pancreatitis, pancreatic phospholipase A(2) (PLA2) in the circulating blood hydrolyzes phospholipids contained in plasma lipoproteins, liberating eicosanoid precursors that are subsequently converted to various eicosanoids. The pathophysiological significance of eicosanoid synthesis via this pathway...

journal_title：Journal of gastroenterology

authors： Motoyoshi M,Sugiyama M,Atomi Y,Kimura W,Nagawa H

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:There have only been a few prospective studies investigating risk factors associated with the development of hepatocellular carcinoma (HCC) among chronic hepatitis B patients all over the world, and no study has been conducted in Japanese population. METHODS:A population-based cohort consisting of 19393 sub...

journal_title：Journal of gastroenterology

authors： Kusakabe A,Tanaka Y,Inoue M,Kurbanov F,Tatematsu K,Nojiri S,Joh T,Tsugane S,Mizokami M

更新日期：2011-01-01 00:00:00

abstract：:Cold restraint stress (CRS) induced vagal-dependent corpus mucosal erosions with hemorrhage in rats. Aggressive factors such as gastric acid, pepsin, and high-amplitude contractions have been reported to be responsible for inducing the formation of gastric lesions. Thyrotropin-releasing hormone (TRH) microinjected int...

journal_title：Journal of gastroenterology

authors： Kaneko H,Taché Y,Kusugami K

更新日期：2002-11-01 00:00:00

abstract：:Changes of hepatic sinusoids are crucial in the pathogenesis of liver cirrhosis and portal hypertension. Liver injury leads to distinct morphological abnormalities such as loss of sinusoidal fenestration, vasoconstriction, and angiogenesis as well as molecular changes. Communication between the two key cells in this h...

journal_title：Journal of gastroenterology

authors： Greuter T,Shah VH

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The ability of serum infliximab level to predict clinical outcome in infliximab therapy in Crohn's disease is unclear. Here, we aimed to clarify the correlation between the timing of loss of response (LOR) to treatment and a decrease in serum infliximab level, and, in addition, to identify an indicator of in...

journal_title：Journal of gastroenterology

authors： Hibi T,Sakuraba A,Watanabe M,Motoya S,Ito H,Sato N,Yoshinari T,Motegi K,Kinouchi Y,Takazoe M,Suzuki Y,Matsumoto T,Kawakami K,Matsumoto T,Hirata I,Tanaka S,Ashida T,Matsui T

更新日期：2014-02-01 00:00:00

abstract：:We present a patient with complication of huge hepatic subcapsular hematoma after extracorporeal shock wave lithotripsy (ESWL) for pancreatic lithotripsy. The hematoma measured 78-110mm. Angiography showed a subcapsular hematoma, rather than a hematoma in the liver. In the arterial phase, the distal end of the small v...

journal_title：Journal of gastroenterology

authors： Hirata N,Kushida Y,Ohguri T,Wakasugi S,Kojima T,Fujita R

更新日期：1999-12-01 00:00:00

abstract：:Asia has intermediate-to-high prevalence and high morbidity of hepatitis B virus (HBV) infection. The use of guideline-recommended nucleos(t)ide analogs with high barrier to resistance, such as entecavir (ETV), tenofovir disoproxil fumarate (TDF), and tenofovir alafenamide (TAF), is one of the key interventions for cu...

journal_title：Journal of gastroenterology

authors： Charlton MR,Alam A,Shukla A,Dashtseren B,Lesmana CRA,Duger D,Payawal DA,Duy Cuong D,Jargalsaikhan G,Cua IHY,Sollano JD,Singh KR,Madan K,Win KM,Kyi KP,Tun KS,Salih M,Rastogi M,Saraf N,Thuy PTT,Hien PTD,Gani RA,

更新日期：2020-09-01 00:00:00

abstract：:Class II antigens are strongly expressed on the inflamed colonic epithelium in inflammatory bowel disease. However, the mechanism of this epithelial class II antigen induction is not fully understood. Increased activities of interferon (IFN)gamma, tumor necrosis factor (TNF)alpha, and interleukin (IL)2 have been shown...

journal_title：Journal of gastroenterology

authors： Horie Y,Chiba M,Suzuki T,Kudo T,Kamata A,Iizuka M,Masamune O

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:High serum immunoglobulin G4 (IgG4) levels and IgG4-positive plasma cell infiltration are characteristic of type 1 autoimmune pancreatitis (AIP). It is unclear whether innate immunity is a cause of type 1 AIP; the possible involvement of microbial infection has been suggested in its pathogenesis. To clarify ...

journal_title：Journal of gastroenterology

authors： Fukui Y,Uchida K,Sakaguchi Y,Fukui T,Nishio A,Shikata N,Sakaida N,Uemura Y,Satoi S,Okazaki K

更新日期：2015-04-01 00:00:00

abstract：:We report a case of Cruveihier-Baumgarten syndrome associated with portal vein thrombosis that developed, slowly during a 2-year period after endoscopic variceal sclerotherapy. The thrombosis led to the disappearance of the venous hum and the dilated abdominal wall veins characteristic of this syndrome. A 73-year-old ...

journal_title：Journal of gastroenterology

authors： Yamakawa O,Ohta H,Watanabe H,Motoo Y,Okai T,Kadoya M,Matsui O,Sawabu N

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Superior mesenteric artery syndrome (SMAS) is caused by compression of the third part of the duodenum between the superior mesenteric artery and the aorta. It occurs most frequently in patients with rapid weight loss. METHODS:We report two young patients, who each presented with a longstanding history of po...

journal_title：Journal of gastroenterology

authors： Lippl F,Hannig C,Weiss W,Allescher HD,Classen M,Kurjak M

更新日期：2002-01-01 00:00:00

abstract：:Duodenal gastrinoma is recognized as a relatively common cause of Zollinger-Ellison syndrome, but its clinical and biological features are not well known. Here we report a case of duodenal gastrinoma with lymph node metastasis which was confirmed by pathology examinations. Hypergastrinemia and gastric acid hypersecret...

journal_title：Journal of gastroenterology

authors： Takasu A,Shimosegawa T,Fukudo S,Asakura T,Uchi M,Kimura K,Kashimura J,Satoh K,Koizumi M,Sasaki I,Hongo M,Suzuki T,Toyota T

更新日期：1998-10-01 00:00:00

abstract：PURPOSE:In patients chronically infected with hepatitis B virus, interferon has been used for the purpose of viral suppression by loss of hepatitis B e antigen (HBeAg) with or without seroconversion to antibody to HBeAg (anti-HBe). However, discussion about the effect of interferon on the development of hepatocellular ...

journal_title：Journal of gastroenterology

authors： Miyake Y,Kobashi H,Yamamoto K

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Abrogating tolerance is a critical step in the pathogenesis of Crohn's disease (CD). T cell-anergy is one of the main mechanisms of tolerance and is regulated by the gene related to anergy in lymphocytes (GRAIL). This study investigated the expressions and regulation of GRAIL in CD and murine colitis models....

journal_title：Journal of gastroenterology

authors： Mukai A,Iijima H,Hiyama S,Fujii H,Shinzaki S,Inoue T,Shiraishi E,Kawai S,Araki M,Hayashi Y,Kondo J,Mizushima T,Kanto T,Egawa S,Nishida T,Tsujii M,Takehara T

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Innate immunity mechanisms have been shown to play a paramount role in organ transplantation. Our aim was to investigate the hypothesis that activation of the interferon system may affect clinically relevant outcomes, such as acute rejection and/or early fibrosis progression, after liver transplantation. ME...

journal_title：Journal of gastroenterology

authors： Minisini R,Giarda P,Grossi G,Bitetto D,Toniutto P,Falleti E,Avellini C,Occhino G,Fabris C,Pirisi M

更新日期：2011-11-01 00:00:00

abstract：:We report a 13-year-old girl who presented with hepatic failure and hemolytic anemia. Laboratory findings showed a normal serum copper level (104 microg/dl), high urinary copper level (2370 microg/dl), and low serum ceruloplasmin level (14.3 microg/dl). Slit-lamp examination revealed Kayser-Fleischer rings on her corn...

journal_title：Journal of gastroenterology

authors： Sakaida I,Kawaguchi K,Kimura T,Tamura F,Okita K

更新日期：2005-06-01 00:00:00

abstract：:We investigated the adverse effects of sulfasalazine in the treatment of inflammatory bowel disease in Japan. In our first survey, adverse effects were observed in 52 out of 751 patients with ulcerative colitis (6.9%) and in 8 out of 221 patients with Crohn's disease (3.6%); i.e., such effects were observed in 60 out ...

journal_title：Journal of gastroenterology

authors： Nakajima H,Munakata A,Yoshida Y

更新日期：1995-11-01 00:00:00