Inflammatory and anti-inflammatory cytokines regulate the recovery from sublethal X irradiation in rat thymus.

abstract：:In a patient with Morbus Hodgkin, structural aberrations of the chromosome type in peripheral lymphocytes were analyzed during radiation therapy (accumulated target dose 44.6 Gy: 22 fractions of 1.8 Gy each and 2 fractions of 2.5 Gy each at the end of the therapy). The blood was sampled about 5 min after a fraction an...

journal_title：Radiation research

authors： Diener A,Stephan G,Vogl T,Lissner J

更新日期：1988-06-01 00:00:00

abstract：:Angiogenesis defines the many steps involved in the growth and migration of endothelial cell-derived blood vessels. This process is necessary for the growth and metastasis of tumors, and considerable effort is being expended to find inhibitors of tumor angiogenesis. This usually involves screening of potential anti-an...

journal_title：Radiation research

authors： Newton DL,Kaur G,Rhim JS,Sausville EA,Rybak SM

更新日期：2001-01-01 00:00:00

abstract：:Studies have causally linked external thyroid radiation exposure in childhood with thyroid cancer. In 1995, investigators conducted relative risk analyses of pooled data from seven epidemiologic studies. Doses were mostly <10 Gy, although childhood cancer therapies can result in thyroid doses >50 Gy. We pooled data fr...

journal_title：Radiation research

authors： Veiga LH,Holmberg E,Anderson H,Pottern L,Sadetzki S,Adams MJ,Sakata R,Schneider AB,Inskip P,Bhatti P,Johansson R,Neta G,Shore R,de Vathaire F,Damber L,Kleinerman R,Hawkins MM,Tucker M,Lundell M,Lubin JH

更新日期：2016-05-01 00:00:00

abstract：:Cisplatin and binuclear rhodium (Rh2) carboxylates appear to potentiate radiation-induced killing of Salmonella typhimurium cells largely as a consequence of one-electron reduction that leads to an active radiolytic product. This conclusion is supported by results from experiments wherein the hydrated electron and the...

journal_title：Radiation research

authors： Richmond RC,Mahtani HK

更新日期：1991-07-01 00:00:00

abstract：:A dose-response relationship was established in normal unanesthetized cats for emetic incidence, latency to onset of vomiting, and duration of emetic activity over a period of 24 h after whole-body exposure to 60Co radiation at selected doses between 7.5 and 90 Gy. Each episode of vomiting, i.e., retching and expulsio...

journal_title：Radiation research

authors： Borison HL,McCarthy LE,Douple EB,Johnson J,Borison R

更新日期：1987-03-01 00:00:00

abstract：:Cytoglobin is a recently identified vertebrate globin whose functions include scavenging reactive oxygen and nitrosative species. In tumor cells, CYGB may function as a tumor suppressor gene. Here we show that knockdown of cytoglobin expression can sensitize human glioma cells to oxidative stress induced by chemical i...

journal_title：Radiation research

authors： Fang J,Ma I,Allalunis-Turner J

更新日期：2011-08-01 00:00:00

abstract：:Radiation nephropathy is one of the common late effects in cancer survivors who received radiotherapy as well as in victims of radiation accidents. The clinical manifestations of radiation nephropathy occur months after exposure. To date, there are no known early biomarkers to predict the future development of radiati...

journal_title：Radiation research

authors： Bhayana S,Song F,Jacob J,Fadda P,Denko NC,Xu-Welliver M,Chakravarti A,Jacob NK

更新日期：2017-12-01 00:00:00

abstract：:We previously described an enhanced sensitivity for cell killing and gamma-H2AX focus induction after both high-dose-rate and continuous low-dose-rate gamma irradiation in 14 primary fibroblast strains derived from hereditary-type retinoblastoma family members (both affected RB1(+/-) probands and unaffected RB1(+/+) p...

journal_title：Radiation research

authors： Wilson PF,Nagasawa H,Fitzek MM,Little JB,Bedford JS

更新日期：2010-01-01 00:00:00

abstract：:Pregnant Wistar-MS rats received a whole-body irradiation of 0-2.6 Gy gamma rays at day 20 of pregnancy. The mother rats were implanted with a diethylstilbestrol (DES) pellet 30 days after weaning, and the female pups delivered by the irradiated mother were treated with DES after maturation. Lactating rats were irradi...

journal_title：Radiation research

authors： Inano H,Suzuki K,Onoda M,Yamanouchi H

更新日期：1996-06-01 00:00:00

abstract：:The lung tolerance in mice after single and fractionated irradiations with p(45)+Be and p(65)+Be neutrons produced at the isochronous cyclotron "CYCLONE" of Louvain-la-Neuve (Belgium) was studied. Cobalt-60 gamma rays were used for control irradiations. The end point was the dose which was lethal to 50% of the mice by...

journal_title：Radiation research

authors： Grégoire V,Beauduin M,Gueulette J,De Coster BM,Octave-Prignot M,Vynckier S,Wambersie A

更新日期：1993-01-01 00:00:00

abstract：:Three-dimensional treatment planning systems used extensively for external-beam treatments have recently been applied for use in brachytherapy. Localization of structures in 3D from imaging studies integrated into computerized systems for planning of implants and evaluation allows 3D dose distributions to be indexed t...

journal_title：Radiation research

authors： Martel MK,Narayana V

更新日期：1998-11-01 00:00:00

abstract：:The capacity of plateau-phase Chinese hamster V79 and normal and transformed C3H-10T1/2 cells for repair of potentially lethal radiation damage (PLD) was evaluated for cells irradiated alone or given combined treatments of heat and radiation. The data show that all cell lines tested could repair PLD and that transform...

journal_title：Radiation research

authors： Raaphorst GP,Azzam EI,Feeley M

更新日期：1988-01-01 00:00:00

abstract：:Trypanothione is a unique diglutathionyl-spermidine conjugate found in abundance in trypanosomes but not in other eukaryotes. Because trypanothione is a naturally occurring polyamine thiol reminiscent of the synthetic drug amifostine, it may be a useful protector against radiation and oxidative stress. For these reaso...

journal_title：Radiation research

authors： Fitzgerald MP,Madsen JM,Coleman MC,Teoh ML,Westphal SG,Spitz DR,Radi R,Domann FE

更新日期：2010-09-01 00:00:00

abstract：:Data are presented for a subset of lymphocytes characterized by FISH as missing painted chromosomal material. These lymphocytes occur in both control and irradiated subjects. These cells have a much greater frequency of one-way translocations than cells in which all of the painted chromosomal material is present. Thei...

journal_title：Radiation research

authors： Edwards A,Maznik N,Moquet J,Hone P,Vinnikov V,Lloyd D,Cox R

更新日期：2002-04-01 00:00:00

abstract：:Abstract Double-strand breaks (DSBs) can be generated in the DNA of mammalian cells when heat-labile sites induced by ionizing radiation within a clustered DNA damage site are thermally transformed to single-strand breaks (SSBs) and combine with other SSBs or heat-labile sites in the opposite DNA strand. When this the...

journal_title：Radiation research

authors： Singh SK,Wu W,Wu W,Wang M,Iliakis G

更新日期：2009-08-01 00:00:00

abstract：:Pentamidine is similar to rhodamine-123 in chemical structure and state of electron charge, and rhodamine-123 was previously shown to be a hyperthermic sensitizer under appropriate cell culture conditions. The present experiments were carried out to determine whether pentamidine would potentiate hyperthermic cell kill...

journal_title：Radiation research

authors： Kim SH,Hong SS,Alfieri AA,Kim JH

更新日期：1988-11-01 00:00:00

abstract：:Whether inner-shell ionizations of DNA atoms, called core ionizations, are critical events for cell inactivation by ionizing radiations such as 100 keV electrons and gamma rays has been investigated. The number of core ionizations in DNA atoms per gray of the two types of radiations is calculated from various Monte Ca...

journal_title：Radiation research

authors： Boissière A,Champion C,Touati A,Hervé du Penhoat MA,Sabatier L,Chatterjee A,Chetioui A

更新日期：2007-04-01 00:00:00

abstract：:Pulmonary carcinomas were recorded in a life-span experiment of male Sprague-Dawley rats exposed to fission neutrons. Mortality-corrected prevalences are obtained by the method of isotonic regression. In a second part of the paper a comparison is made with data obtained earlier for radon-daughter inhalations in the sa...

journal_title：Radiation research

authors： Chmelevsky D,Kellerer AM,Lafuma J,Morin M,Masse R

更新日期：1984-06-01 00:00:00

abstract：:Reverse-biased silicon p-n junction arrays using Silicon-On-Insulator technology have been proposed as microdosimeters. The performance of such detectors in boron neutron capture therapy (BNCT) is discussed. This work provides the first reported measurements using boron-coated silicon diode arrays as microdosimeters i...

journal_title：Radiation research

authors： Bradley PD,Rosenfeld AB,Allen B,Coderre J,Capala J

更新日期：1999-03-01 00:00:00

abstract：:The threat of exposure to ionizing radiation from a nuclear reactor accident or deliberate terrorist actions is a significant public health concern. The lung is particularly susceptible to radiation-induced injury from external sources or inhalation of radioactive particles from radioactive fallout. Radiation-induced ...

journal_title：Radiation research

authors： Christofidou-Solomidou M,Pietrofesa RA,Arguiri E,Koumenis C,Segal R

更新日期：2017-11-01 00:00:00

abstract：:Radiation is an independent risk factor for cardiovascular and cerebrovascular disease in cancer patients. Modern radiotherapy techniques reduce the volume of the heart and major coronary vessels exposed to high doses, but some exposure is often unavoidable. Radiation damage to the myocardium is caused primarily by in...

journal_title：Radiation research

authors： Stewart FA,Hoving S,Russell NS

更新日期：2010-12-01 00:00:00

abstract：:During the pulsed-electron beam direct grafting of neat styrene onto poly(tetrafluoroethylene-co-hexafluoropropylene) (FEP) substrate, the radiolytically-produced styryl and carbon-centered FEP radicals undergo various desired and undesired competing reactions. In this study, a high-dose rate is used to impede the und...

journal_title：Radiation research

authors： Kim B,Weaver A,Chumakov M,Pazos IM,Poster DL,Gaskell K,Han DH,Scherer G,Yandrasits MA,Lee BC,Al-Sheikhly M

更新日期：2018-09-01 00:00:00

abstract：:Both plant senescence and plant response to ionizing radiation involve changes in gene expression and epigenetic profiles, that rely on the formation of reactive oxygen species. However, how the developmental stage of a plant affects its response to ionizing radiation has not been extensively studied. In this study, o...

journal_title：Radiation research

authors： Sidler C,Li D,Kovalchuk O,Kovalchuk I

更新日期：2015-02-01 00:00:00

abstract：:Exposure of cells to heat induces thermotolerance, a transient resistance to subsequent heat challenges. It has been shown that thermotolerance is correlated in time with the enhanced synthesis of heat shock proteins. In this study, the association of induced heat shock proteins with various cellular fractions was inv...

journal_title：Radiation research

authors： Murnane JP,Li GC

更新日期：1985-03-01 00:00:00

abstract：:Resistance to radiation is considered to be an important reason for local failure after radiotherapy and tumor recurrence. However, the exact mechanisms of tumor resistance remain poorly understood. Current investigations of microRNAs as potential diagnostic and therapeutic tools for cancer treatment have shown promis...

journal_title：Radiation research

authors： Mueller AK,Lindner K,Hummel R,Haier J,Watson DI,Hussey DJ

更新日期：2016-06-01 00:00:00

abstract：:The dependence of relative biological effectiveness (RBE) on photon energy is a topic of extensive discussions. The increasing amount of in vitro data in the low-energy region indicates this to be a complex dependence that is influenced by the end point and cell line studied. In the present investigation, the RBE of 1...

journal_title：Radiation research

authors： Lehnert A,Dörr W,Lessmann E,Pawelke J

更新日期：2008-03-01 00:00:00

abstract：:Inhalation and ingestion of 137Cs and other long-lived radionuclides can occur after large-scale accidental or malicious radioactive contamination incidents, resulting in a complex temporal pattern of radiation dose/dose rate, influenced by radionuclide pharmacokinetics and chemical properties. High-throughput radiati...

journal_title：Radiation research

authors： Shuryak I,Ghandhi SA,Turner HC,Weber W,Melo D,Amundson SA,Brenner DJ

更新日期：2020-10-16 00:00:00

abstract：:The placental transfer and distribution of 241Am in the feto-placental system were studied in pregnant rats. Rats were injected intravenously with 241Am citrate at 15 or 18 days of gestation. Groups injected at 15 days of gestation were sacrificed 2, 24, 48, or 120 hr after injection, and the group injected at 18 days...

journal_title：Radiation research

authors： Hisamatsu S,Takizawa Y

更新日期：1983-04-01 00:00:00

abstract：:The mechanisms underlying hepatocellular damage after irradiation are obscure. We identified genes induced by radiation in isolated rat hepatocytes in vitro by cDNA array gene expression analysis and then screened in vivo experiments with those same genes using real-time PCR and Western blotting. Hepatocytes were irra...

journal_title：Radiation research

authors： Christiansen H,Batusic D,Saile B,Hermann RM,Dudas J,Rave-Frank M,Hess CF,Schmidberger H,Ramadori G

更新日期：2006-03-01 00:00:00

abstract：:Statistical analysis of Monte Carlo simulations of positive ion track structure is presented for 1 MeV protons passing outside an absorbing region of interest. Energy deposition and production of ionization within the region occur only by delta-ray transport from the ion's path. Depositions in spherical absorber regio...

journal_title：Radiation research

authors： Wilson WE

更新日期：1994-12-01 00:00:00