Sequence and organization of the Mamestra configurata nucleopolyhedrovirus genome.

abstract：:Glycoproteins gB and gH/gL are required for entry of Epstein-Barr virus (EBV) into cells, but the role of each glycoprotein and how they function together to mediate fusion is unclear. Analysis of the functional homology of gB from the closely related primate gammaherpesvirus, rhesus lymphocryptovirus (Rh-LCV), showed...

journal_title：Virology

authors： Plate AE,Reimer JJ,Jardetzky TS,Longnecker R

更新日期：2011-04-25 00:00:00

abstract：:Human keratinocytes (HKc) immortalized by human papillomavirus type 16 DNA (HKc/HPV16) progress toward malignancy through growth factor-independent (HKc/GFI) and differentiation-resistant stages (HKc/DR). This progression is associated with a loss of sensitivity to growth inhibition by both all-trans-retinoic acid (RA...

journal_title：Virology

authors： Mi Y,Borger DR,Fernandes PR,Pirisi L,Creek KE

更新日期：2000-05-10 00:00:00

abstract：:The emergence and re-emergence of Zika virus (ZIKV), is a cause for international concern. These highly pathogenic arboviruses represent a serious health burden in tropical and subtropical areas worldwide. Despite these burdens, antiviral therapies do not exist, and inhibitors of ZIKV are therefore urgently needed. To...

journal_title：Virology

authors： Chen H,Lao Z,Xu J,Li Z,Long H,Li D,Lin L,Liu X,Yu L,Liu W,Li G,Wu J

更新日期：2020-07-01 00:00:00

abstract：:We have utilized glycan microarray technology to determine the receptor binding properties of early isolates from the recent 2009 H1N1 human pandemic (pdmH1N1), and compared them to North American swine influenza isolates from the same year, as well as past seasonal H1N1 human isolates. We showed that the pdmH1N1 stra...

journal_title：Virology

authors： Bradley KC,Jones CA,Tompkins SM,Tripp RA,Russell RJ,Gramer MR,Heimburg-Molinaro J,Smith DF,Cummings RD,Steinhauer DA

更新日期：2011-05-10 00:00:00

abstract：:Segment 7 (M) of the cold-adapted live influenza A virus vaccine plays a primary role in the ability of this virus to interfere with the replication of wild-type influenza A viruses. This conclusion is based on several lines of evidence. Single gene reassortant viruses derived by crossing influenza A/Ann Arbor/6/60 (H...

journal_title：Virology

authors： Whitaker-Dowling P,Zvolenski R,Youngner JS

更新日期：1991-01-01 00:00:00

abstract：:The nucleotide sequence of two variants of coconut tinangaja viroid (CTiV) were obtained. Both sequence variants are 254 nucleotide residues in size but differ in sequence at two positions. In comparisons with other viroids, the sequences and proposed secondary structure of CTiV show most homology with the 246 nucleot...

journal_title：Virology

authors： Keese P,Osorio-Keese ME,Symons RH

更新日期：1988-02-01 00:00:00

abstract：:Tetherin has been defined as a restriction factor of HIV-1 and several other enveloped viruses. However, the significance of tetherin in viral infection remains to be further addressed. Here, we investigated whether tetherin plays a role in HSV-2 infection. Our study revealed that overexpression of tetherin restricted...

journal_title：Virology

authors： Liu Y,Luo S,He S,Zhang M,Wang P,Li C,Huang W,Hu B,Griffin GE,Shattock RJ,Hu Q

更新日期：2015-01-15 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV-68) replicates robustly in cell culture, providing a model for studying viral genome replication during de novo infection of tumor-associated herpesviruses. We have previously identified a 1.25-kb origin of lytic replication (oriLyt) for MHV-68. To further investigate the molecular mech...

journal_title：Virology

authors： Gong D,Qi J,Arumugaswami V,Sun R,Deng H

更新日期：2009-05-10 00:00:00

abstract：:The HIV-1 Nef protein causes a decrease in major histocompatibility complex (MHC) class I and CD4 molecule expression on the cell surface. To determine if Nef can affect components of the innate immune response, we assessed the ability of Nef to alter the cell surface expression of human CD1d. In cells co-expressing C...

journal_title：Virology

authors： Cho S,Knox KS,Kohli LM,He JJ,Exley MA,Wilson SB,Brutkiewicz RR

更新日期：2005-07-05 00:00:00

abstract：:Sequence analysis of the murine gamma-herpesvirus 68 (gammaHV68) genome previously identified several open reading frames (ORFs) located at the left end of the viral genome that do not share homology with other known herpesvirus or cellular genes. Here, we show that one of these ORFs, M4, encodes a secreted glycoprote...

journal_title：Virology

authors： Evans AG,Moorman NJ,Willer DO,Speck SH

更新日期：2006-01-20 00:00:00

abstract：:The most recent introduction of an avian influenza A virus without reassortment into mammals occurred in 1979 when H1N1 strains could be isolated from diseased pigs in northern Europe. This newly introduced avian virus formed a stable lineage in pigs and, in the meantime, spread all over Europe. In 1991 highly pathoge...

journal_title：Virology

authors： Ludwig S,Haustein A,Kaleta EF,Scholtissek C

更新日期：1994-07-01 00:00:00

abstract：:Monoclonal antibodies to the matrix or E1 glycoprotein of mouse hepatitis virus (MHV) were tested for their ability to protect mice from a normally lethal challenge of MHV-4. Four antibodies were tested, and two of these, J.1.3 and J.3.9, were protective. Protection did not correlate with virus neutralization in vitro...

journal_title：Virology

authors： Fleming JO,Shubin RA,Sussman MA,Casteel N,Stohlman SA

更新日期：1989-01-01 00:00:00

abstract：:Here we describe the complete genome sequences of two strains of Usutu virus (USUV), a mosquito-borne member of the genus Flavivirus in the Japanese encephalitis virus (JEV) serogroup. USUV was detected in Austria in 2001 causing a high mortality rate in blackbirds; the reference strain (SAAR-1776) was isolated in 195...

journal_title：Virology

authors： Bakonyi T,Gould EA,Kolodziejek J,Weissenböck H,Nowotny N

更新日期：2004-10-25 00:00:00

abstract：:The enveloped virions of two strains of a granulosis virus, a synergistic Hawaiian (GVH) and a nonsynergistic Oregonian (GVO) strain which infect the armyworm, Pseudaletia unipuncta, were liberated from their capsules with 0.02 N NaOH and purified by filtration through membrane filters. The envelopes were solubilized ...

journal_title：Virology

authors： Yamamoto T,Tanada Y

更新日期：1979-04-15 00:00:00

abstract：:CD8(+) T-lymphocytes from HIV-1 infected individuals express unidentified factors that suppress viral replication by inhibiting HIV-1 gene expression. We examined the role of epigenetics in modulating the HIV-1 suppressive factors expressed by primary CD8(+) T cells from subjects naturally controlling virus replicatio...

journal_title：Virology

authors： Saunders KO,Freel SA,Overman RG,Cunningham CK,Tomaras GD

更新日期：2010-09-15 00:00:00

abstract：:Several strains of tobacco ringspot virus (TobRV) support the replication and encapsidation of satellite tobacco ringspot virus RNA (STobRV RNA). We have compared the nucleotide sequences of four STobRV RNAs, each initially associated with a different isolate of TobRV. A STobRV RNA from a geranium isolate of TobRV and...

journal_title：Virology

authors： Buzayan JM,McNinch JS,Schneider IR,Bruening G

更新日期：1987-09-01 00:00:00

abstract：:The HIV-1 protein Vpr enhances macrophage infection, triggers G2 cell cycle arrest, and targets cells for NK-cell killing. Vpr acts through the CRL4(DCAF1) ubiquitin ligase complex to cause G2 arrest and trigger expression of NK ligands. Corresponding ubiquitination targets have not been identified. UNG2 and SMUG1 are...

journal_title：Virology

authors： Casey Klockow L,Sharifi HJ,Wen X,Flagg M,Furuya AK,Nekorchuk M,de Noronha CM

更新日期：2013-09-01 00:00:00

abstract：:To illuminate the molecular basis for host range restriction of parainfluenza virus replication, we have examined the types of virus macromolecules produced during abortive infection of nonpermissive MDBK cells with human parainfluenza virus type 1 (hPIV1). While these cells do not support production of hPIV1 virus, t...

journal_title：Virology

authors： Tao T,Ryan KW

更新日期：1996-06-01 00:00:00

abstract：:Simian-human immunodeficiency virus encoding both reverse transcriptase (RT) and envelope genes of HIV-1 (RT Env SHIV) is important for evaluating biomedical prevention modalities for HIV/AIDS. We describe virological characterization of a clade B RT Env SHIV following infection of macaques via multiple routes. In viv...

journal_title：Virology

authors： Pal R,Galmin L,Pereira LE,Li B,Zhang J,Li D,Francis J,McNicholl JM,Weiss DE,Smith JM

更新日期：2012-10-10 00:00:00

abstract：:The porcine lymphotropic herpesviruses (PLHV) are discussed as possible risk factors in xenotransplantation because of the high prevalence of PLHV-1, PLHV-2 and PLHV-3 in pig populations world-wide and the fact that PLHV-1 has been found to be associated with porcine post-transplant lymphoproliferative disease. To pro...

journal_title：Virology

authors： Lindner I,Ehlers B,Noack S,Dural G,Yasmum N,Bauer C,Goltz M

更新日期：2007-01-20 00:00:00

abstract：:Experiments were undertaken to determine if the sera of avian sarcoma virus-infected 15I5 X 7(2) chickens exhibit antibody reactivity for species of endogenous retroviral envelope glycoprotein expressed in 15I5 X 7(2) fibroblasts. Two viruses were used for infection of the 15I5 X 7(2) chickens, Pr-A and cl. 85; the en...

journal_title：Virology

authors： Halpern MS,Deery DT,Flores LJ,Fujita DJ,Mason WS

更新日期：1983-01-30 00:00:00

abstract：:The 50-70 S RNA complex of a clone of Kirsten murine leukemia virus (Ki-MLV), propagated in NIH 3T3 cells, as well as that of a Moloney (Mo)-MLV, propagated in a mouse thymus-bone marrow cell line, contained an approximately 30 S RNA of unknown biological activity in addition to 38 S genomic RNA. The approximately 30 ...

journal_title：Virology

authors： Duesberg PH,Scolnick EM

更新日期：1977-11-01 00:00:00

abstract：:Vaccinia topoisomerase provides a model system for structure-function analysis of the type IB topoisomerase family. Here we performed an alanine scan of eight positions in the beta4 and beta5 strands of the N-terminal domain (Leu57, Ile58, Phe59, Val60, Gly61, Ser62, Gln69 and Gly73) and eight positions in the alpha8-...

journal_title：Virology

authors： Tian L,Shuman S

更新日期：2007-03-15 00:00:00

abstract：:In transient gene expression assays we observed an increase in expression of the bacterial chloramphenicol acetyl-transferase (CAT) gene, under the transcriptional control of the HIV-1 LTR (pLTR-CAT), when this plasmid was cotransfected into Vero or MRC-5 cells with a plasmid containing either the HCMV immediate early...

journal_title：Virology

authors： Rando RF,Srinivasan A,Feingold J,Gonczol E,Plotkin S

更新日期：1990-05-01 00:00:00

abstract：:The repetitive DNA sequences of the genome of Molluscum contagiosum virus type 1 (MCV-1) have been localized within the terminal regions of the viral genome corresponding to the BamHI MCV-1 DNA fragments B (18 kbp; 0 to 0.095 map units (m.u.)) and E (10.5 kbp; 0.944 to 1 m.u.). The fine mapping of these particular reg...

journal_title：Virology

authors： Bugert JJ,Raab K,Rösen-Wolff A,Janssen W,Darai G

更新日期：1993-01-01 00:00:00

abstract：:Recently, we reported that in vitro and in vivo persistent infection of neurons by lymphocytic choriomeningitis virus (LCMV) downregulated GAP43 expression, a protein involved in neuronal plasticity associated with learning and memory. Here, we investigated the transcriptional and posttranscriptional events involved. ...

journal_title：Virology

authors： Cao W,Oldstone MB,De La Torre JC

更新日期：1997-04-14 00:00:00

abstract：:Repression of human papillomavirus (HPV) E6 and E7 oncogenes in established cervical carcinoma cell lines causes senescence due to reactivation of cellular tumor suppressor pathways. Here, we determined whether ongoing expression of HPV16 or HPV18 oncogenes is required for the proliferation of primary human cervical c...

journal_title：Virology

authors： Magaldi TG,Almstead LL,Bellone S,Prevatt EG,Santin AD,DiMaio D

更新日期：2012-01-05 00:00:00

abstract：:Animal viruses profoundly modify the metabolism of lipids, the synthesis of new membranes, and membrane traffic. These alterations are related to the replication of viral genomes. Addition of oleic acid from the beginning of poliovirus infection inhibits the appearance of virus polypeptides at concentrations that do n...

journal_title：Virology

authors： Guinea R,Carrasco L

更新日期：1991-11-01 00:00:00

abstract：:Varicella zoster virus (VZV) is a neurotropic alphaherpesvirus that, following primary infection (varicella), establishes latency in sensory, autonomic, sympathetic and parasympathetic neurons, where it remains until reactivation (zoster). VZV-specific cell-mediated immune responses maintain VZV latency; thus, immunos...

journal_title：Virology

authors： Como CN,Pearce CM,Cohrs RJ,Baird NL

更新日期：2018-09-01 00:00:00

abstract：:Infection with hepatitis B virus (HBV) has been detected in human populations throughout the world, as well as in a number of ape species (Pan troglodytes, Gorilla gorilla, gibbons [Nomascus and Hylobates species] and Pongo pygmaeus). To investigate the distribution of naturally occurring HBV infection in these specie...

journal_title：Virology

authors： Starkman SE,MacDonald DM,Lewis JC,Holmes EC,Simmonds P

更新日期：2003-09-15 00:00:00