Coconut tinangaja viroid: sequence homology with coconut cadang-cadang viroid and other potato spindle tuber viroid related RNAs.


:The nucleotide sequence of two variants of coconut tinangaja viroid (CTiV) were obtained. Both sequence variants are 254 nucleotide residues in size but differ in sequence at two positions. In comparisons with other viroids, the sequences and proposed secondary structure of CTiV show most homology with the 246 nucleotide residue variant of coconut cadang-cadang viroid (CCCV (246]. Several regions throughout the rod-like molecules of CTiV show significant structural and sequence homology with other RNAs related to potato spindle tuber viroid. These homologies include a centrally positioned uridine bulged G:C helix and a 17 nucleotide residue sequence found in common with hop stunt viroid in the left-hand end loop of both viroids.






Keese P,Osorio-Keese ME,Symons RH




Has Abstract


1988-02-01 00:00:00














  • 3'-terminal nucleotide sequences important for the accumulation of cowpea mosaic virus M-RNA.

    abstract::The location of nucleotide sequences important in determining the extent of cowpea mosaic virus M-RNA accumulation in cowpea protoplasts has been analyzed by deletion mutagenesis of full-length cDNA clones from which infectious transcripts can be produced in vitro. The results suggest that cis-acting sequences which d...


    pub_type: 杂志文章


    authors: Rohll JB,Holness CL,Lomonossoff GP,Maule AJ

    更新日期:1993-04-01 00:00:00

  • MMTV does not encode viral microRNAs but alters the levels of cancer-associated host microRNAs.

    abstract::Mouse mammary tumor virus (MMTV) induces breast cancer in mice in the absence of known virally-encoded oncogenes. Tumorigenesis by MMTV is thought to occur primarily through insertional mutagenesis, leading to the activation of cellular proto-oncogenes and outgrowth of selected cells. Here we investigated whether MMTV...


    pub_type: 杂志文章


    authors: Kincaid RP,Panicker NG,Lozano MM,Sullivan CS,Dudley JP,Mustafa F

    更新日期:2018-01-01 00:00:00

  • Strict conservation of the retroviral nucleocapsid protein zinc finger is strongly influenced by its role in viral infection processes: characterization of HIV-1 particles containing mutant nucleocapsid zinc-coordinating sequences.

    abstract::The retroviral nucleocapsid (NC) protein contains highly conserved amino acid sequences (-Cys-X2-Cys-X4-His-X4-Cys-) designated retroviral (CCHC) Zn2+ fingers. The NC protein of murine leukemia viruses contains one NC Zn2+ finger and mutants that were competent in metal binding (CCCC and CCHH) packaged wild-type level...


    pub_type: 杂志文章


    authors: Gorelick RJ,Gagliardi TD,Bosche WJ,Wiltrout TA,Coren LV,Chabot DJ,Lifson JD,Henderson LE,Arthur LO

    更新日期:1999-03-30 00:00:00

  • Nonlinear ribosome migration on cauliflower mosaic virus 35S RNA in transgenic tobacco plants.

    abstract::Cauliflower mosaic virus (CaMV) uses a specialised translation mechanism to bypass the long leader sequence of the 35S RNA. The effect of the CaMV 35S RNA leader sequence on the expression of a downstream beta-glucuronidase (GUS) reporter gene was studied in transgenic tobacco plants. Enzymatic GUS assays of these tra...


    pub_type: 杂志文章


    authors: Schärer-Hernández N,Hohn T

    更新日期:1998-03-15 00:00:00

  • Combination of Adt-O1Manisa and Ad5-boIFNλ3 induces early protective immunity against foot-and-mouth disease in cattle.

    abstract::Foot-and-mouth-disease (FMD) remains the most infectious livestock disease worldwide. Although commercially available inactivated or adenovirus-vectored-vaccines (Ad5-FMD) are effective, they require 5-7 days to induce protection. Therefore, new control strategies that stimulate rapid immune responses are needed. Expr...


    pub_type: 杂志文章


    authors: Diaz-San Segundo F,Montiel NA,Sturza DF,Perez-Martin E,Hickman D,Ramirez-Medina E,Grubman MJ,de Los Santos T

    更新日期:2016-12-01 00:00:00

  • One hundred years of poliovirus pathogenesis.

    abstract::Poliovirus was first isolated nearly 100 years ago in a landmark experiment that established the viral etiology of poliomyelitis. This discovery stimulated investigation of the pathogenesis of poliomyelitis in many laboratories. Nearly 50 years later, when two effective poliovirus vaccines were developed, the impetus ...


    pub_type: 杂志文章,评审


    authors: Racaniello VR

    更新日期:2006-01-05 00:00:00

  • Vesicular stomatitis virus and its defective interfering particles exhibit in vitro transcriptional and replicative competition for purified L-NS polymerase molecules.

    abstract::We have quantitated replication of the RNA genomes of vesicular stomatitis virus (VSV) and its defective interfering (DI) particles in a BHK21 cell-free system into which nucleocapsids were introduced in varying amounts and ratios, with or without addition of purified virus polymerase components. The quantitative tran...


    pub_type: 杂志文章


    authors: Giachetti C,Holland JJ

    更新日期:1989-05-01 00:00:00

  • Production and characterization of monoclonal antibodies to porcine group C rotaviruses cross-reactive with group A rotaviruses.

    abstract::Five monoclonal antibodies (MAbs) to porcine group (gp) C rotaviruses (Cowden and Ah strains) reactive with both gp A and C rotaviruses in cell culture immunofluorescence (CCIF) tests were produced and characterized. These MAbs reacted with three strains of gp A and two strains of gp C rotaviruses in a CCIF test and w...


    pub_type: 杂志文章


    authors: Tsunemitsu H,Ojeh CK,Jiang B,Simkins RA,Weilnau PA,Saif LJ

    更新日期:1992-11-01 00:00:00

  • Low pH-dependent Sindbis virus-induced fusion of BHK cells: differences between strains correlate with amino acid changes in the E1 glycoprotein.

    abstract::Expression of alphavirus glycoproteins on the surface of infected cells leads to cell fusion after exposure to acidic pH. Two strains of Sindbis virus, AR339 (SV) and neuroadapted Sindbis virus (NSV), which differ in virulence for weanling mice, were found to differ in pH-dependent fusion. BHK-21 cells infected with S...


    pub_type: 杂志文章


    authors: Boggs WM,Hahn CS,Strauss EG,Strauss JH,Griffin DE

    更新日期:1989-04-01 00:00:00

  • Norovirus classification and proposed strain nomenclature.

    abstract::Without a virus culture system, genetic analysis becomes the principal method to classify norovirus (NoV) strains. Currently, classification of NoV strains beneath the species level has been based on sequences from different regions of the viral genome. As a result, the phylogenetic insights of some virus were not app...


    pub_type: 杂志文章


    authors: Zheng DP,Ando T,Fankhauser RL,Beard RS,Glass RI,Monroe SS

    更新日期:2006-03-15 00:00:00

  • Octapartite negative-sense RNA genome of High Plains wheat mosaic virus encodes two suppressors of RNA silencing.

    abstract::High Plains wheat mosaic virus (HPWMoV, genus Emaravirus; family Fimoviridae), transmitted by the wheat curl mite (Aceria tosichella Keifer), harbors a monocistronic octapartite single-stranded negative-sense RNA genome. In this study, putative proteins encoded by HPWMoV genomic RNAs 2-8 were screened for potential RN...


    pub_type: 杂志文章


    authors: Gupta AK,Hein GL,Graybosch RA,Tatineni S

    更新日期:2018-05-01 00:00:00

  • Porcine reproductive and respiratory syndrome virus non-structural protein 1 suppresses tumor necrosis factor-alpha promoter activation by inhibiting NF-κB and Sp1.

    abstract::The objective of this study was to identify porcine reproductive and respiratory syndrome virus (PRRSV)-encoded proteins that are responsible for the inhibition of TNF-α expression and the mechanism(s) involved in this phenomenon. Using a TNF-α promoter reporter system, the non-structural protein 1 (Nsp1) was found to...


    pub_type: 杂志文章


    authors: Subramaniam S,Kwon B,Beura LK,Kuszynski CA,Pattnaik AK,Osorio FA

    更新日期:2010-10-25 00:00:00

  • Helicase ATPase activity of the Tobacco mosaic virus 126-kDa protein modulates replicase complex assembly.

    abstract::Mutations disrupting helicase domain motifs of the Tobacco mosaic virus 126/183-kDa proteins were investigated for their effect on replicase function and assembly. These mutations inhibited virus replication but did not affect 126-kDa induced N gene resistance or RNAi suppression. However, in vivo expressed 126-kDa mo...


    pub_type: 杂志文章


    authors: Wang X,Kelman Z,Culver JN

    更新日期:2010-07-05 00:00:00

  • Evaluation of the zoonotic potential of multiple subgroups of clade influenza A (H5N8) virus.

    abstract::Clade H5N8 highly pathogenic avian influenza viruses (HPAIVs) have spread worldwide. Phylogenetic analysis identified two genetic groups of the H5N8 HPAIVs in South Korea; group A evolved further into four subgroups. Here, we examined the zoonotic potential, both in vivo and in vitro, of genetically distinct s...


    pub_type: 杂志文章


    authors: Lee YN,Lee EK,Song BM,Heo GB,Woo SH,Cheon SH,Lee YJ

    更新日期:2018-03-01 00:00:00

  • The roles of the red clover necrotic mosaic virus capsid and cell-to-cell movement proteins in systemic infection.

    abstract::The red clover necrotic mosaic dianthovirus (RCNMV) genome is split between two single-stranded RNA species termed RNA-1 and RNA-2. RNA-2 is required for infection of whole plants but is dispensable for infection and virion formation in protoplasts. We have used full-length cDNA clones of RNA-1 and -2 from which infec...


    pub_type: 杂志文章


    authors: Xiong Z,Kim KH,Giesman-Cookmeyer D,Lommel SA

    更新日期:1993-01-01 00:00:00

  • Antigenic mapping of the surface proteins of rhesus rotavirus.

    abstract::Monoclonal antibodies have been produced and used to map the functional topography of the surface proteins of rhesus rotavirus (RRV) that mediate viral neutralization. Ten monoclonal antibodies directed to VP7 were studied in neutralization assays and competitive binding studies. A large neutralization domain with sev...


    pub_type: 杂志文章


    authors: Shaw RD,Vo PT,Offit PA,Coulson BS,Greenberg HB

    更新日期:1986-12-01 00:00:00

  • Differential subcellular localization of hepatitis C virus core gene products.

    abstract::The expression of the core gene of two different hepatitis C virus (HCV) isolates was analyzed. In the presence of its downstream E1 envelope protein sequence, two major core protein products with molecular masses of 21 kDa (P21) and 19 kDa (P19) and a minor protein product with molecular mass of 16 kDa (P16) were det...


    pub_type: 杂志文章


    authors: Lo SY,Masiarz F,Hwang SB,Lai MM,Ou JH

    更新日期:1995-11-10 00:00:00

  • Tumorigenicity of adenovirus-transformed cells: region E1A of adenovirus 12 confers resistance to natural killer cells.

    abstract::Sensitivity of a library of rat cells transformed in vitro with viable recombinant adenoviruses to natural killer (NK) cells and allogeneic cytotoxic T cells has been studied and correlated with their oncogenic potential in syngeneic rats. All cell lines transformed with the sub370-12E1AB virus (containing E1A and E1B...


    pub_type: 杂志文章


    authors: Sawada Y,Föhring B,Shenk TE,Raska K Jr

    更新日期:1985-12-01 00:00:00

  • The AG recombinant IbNG and novel strains of group M HIV-1 are common in Cameroon.

    abstract::The genetic diversity of group M HIV-1 is highest in west central Africa. Blood samples from four locations in Cameroon were collected to determine the molecular epidemiology of HIV-1. The C2-V5 region of envelope was sequenced from 39 of the 40 samples collected, and 7 samples were sequenced across the genome. All st...


    pub_type: 杂志文章


    authors: Carr JK,Torimiro JN,Wolfe ND,Eitel MN,Kim B,Sanders-Buell E,Jagodzinski LL,Gotte D,Burke DS,Birx DL,McCutchan FE

    更新日期:2001-07-20 00:00:00

  • Papillomavirus E2 protein is regulated by specific fibroblast growth factor receptors.

    abstract::The papillomavirus (PV) E2 protein activates transcription and replication by recruiting cellular proteins and the E1 DNA helicase to their binding sites in the viral genome. We recently demonstrated that phosphorylation of tyrosine 102 in the bovine papillomavirus (BPV-1) E2 protein restricts these activities and tha...


    pub_type: 杂志文章


    authors: DeSmet M,Kanginakudru S,Jose L,Xie F,Gilson T,Androphy EJ

    更新日期:2018-08-01 00:00:00

  • Assessment and optimization of rolling circle amplification protocols for the detection and characterization of badnaviruses.

    abstract::The genus Badnavirus is characterized by members that are genetically and serologically heterogeneous which presents challenges for their detection and characterization. The presence of integrated badnavirus-like sequences in some host species further complicates detection using PCR-based protocols. To address these c...


    pub_type: 杂志文章


    authors: Sukal AC,Kidanemariam DB,Dale JL,Harding RM,James AP

    更新日期:2019-03-01 00:00:00

  • Rapid adaptation of avian H7N9 virus in pigs.

    abstract::How the H7N9 avian influenza virus gained the distinct ability to infect humans is unclear. Pigs are an important host in influenza virus ecology because they are susceptible to infection with both avian and human influenza viruses and are often involved in interspecies transmission. Here, we passaged one avian isolat...


    pub_type: 杂志文章


    authors: Xu L,Bao L,Deng W,Zhu H,Li F,Chen T,Lv Q,Yuan J,Xu Y,Li Y,Yao Y,Gu S,Yu P,Chen H,Qin C

    更新日期:2014-03-01 00:00:00

  • The measles virus phosphoprotein interacts with the linker domain of STAT1.

    abstract::The measles virus (MV) phosphoprotein (P) and V proteins block the interferon (IFN) response by impeding phosphorylation of the signal transducer and activator of transcription 1 (STAT1) by the Janus kinase 1 (JAK1). We characterized how STAT1 mutants interact with P and JAK1 phosphorylation. Certain mutants of the li...


    pub_type: 杂志文章


    authors: Devaux P,Priniski L,Cattaneo R

    更新日期:2013-09-01 00:00:00

  • Alteration of intrahepatic cytokine expression and AP-1 activation in transgenic mice expressing hepatitis C virus core protein.

    abstract::Hepatitis C virus (HCV) infection often leads to the development of hepatocellular carcinoma (HCC), but its molecular mechanism has not been clearly elucidated. Previously, transgenic mice constitutively expressing HCV core protein have been shown to develop HCC, suggesting a pivotal role of the core protein in hepato...


    pub_type: 杂志文章


    authors: Tsutsumi T,Suzuki T,Moriya K,Yotsuyanagi H,Shintani Y,Fujie H,Matsuura Y,Kimura S,Koike K,Miyamura T

    更新日期:2002-12-20 00:00:00

  • Memory T cells protect chicks from acute infectious bronchitis virus infection.

    abstract::Infectious bronchitis has remained one of the most difficult to control diseases in poultry since it was first described in 1931. Previous studies demonstrated that primary CD8(+) T lymphocytes collected at 10 days post-infection (p.i.) are important in controlling acute infection. To further investigate the role of m...


    pub_type: 杂志文章


    authors: Pei J,Briles WE,Collisson EW

    更新日期:2003-02-15 00:00:00

  • Recombinant human parainfluenza virus type 2 with mutations in V that permit cellular interferon signaling are not attenuated in non-human primates.

    abstract::The HPIV2 V protein inhibits type I interferon (IFN) induction and signaling. To manipulate the V protein, whose coding sequence overlaps that of the polymerase-associated phosphoprotein (P), without altering the P protein, we generated an HPIV2 virus in which P and V are expressed from separate genes (rHPIV2-P+V). rH...


    pub_type: 杂志文章


    authors: Schaap-Nutt A,D'Angelo C,Amaro-Carambot E,Nolan SM,Davis S,Wise SM,Higgins C,Bradley K,Kim O,Mayor R,Skiadopoulos MH,Collins PL,Murphy BR,Schmidt AC

    更新日期:2010-10-10 00:00:00

  • Simian virus 40 Vp2/3 small structural proteins harbor their own nuclear transport signal.

    abstract::We have used a microinjection approach to identify a domain of the simian virus 40 (SV40) structural proteins Vp2 and Vp3(Vp2/3) responsible for their nuclear transport. By using both synthetic peptides, containing small regions of Vp2/3 conjugated to bovine serum albumin (BSA), and beta-galactosidase-Vp3 fusion prote...


    pub_type: 杂志文章


    authors: Clever J,Kasamatsu H

    更新日期:1991-03-01 00:00:00

  • Sequence and secondary structure analysis of the 5'-terminal region of flavivirus genome RNA.

    abstract::The 5'-terminal noncoding region sequences were determined for the genome RNAs of seven strains of St. Louis encephalitis virus (SLEV) and one strain of West Nile virus (WNV) using a single synthetic cDNA primer complementary to the 5'-terminus of the coding region of a strain of WNV RNA. The 5'-terminal sequences obt...


    pub_type: 杂志文章


    authors: Brinton MA,Dispoto JH

    更新日期:1988-02-01 00:00:00

  • Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures.

    abstract::Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amin...


    pub_type: 杂志文章


    authors: Schoppel K,Hassfurther E,Britt W,Ohlin M,Borrebaeck CA,Mach M

    更新日期:1996-02-01 00:00:00

  • Different evolution of simian immunodeficiency virus in a natural host and a new host.

    abstract::To address the mechanisms of host-virus adaptation and pathogenesis of lentiviral infections, we compared the evolution of the same isolate of simian immunodeficiency virus (SIVsmm9) in two different situations: nonpathogenic infection of its natural host, the sooty mangabey, and AIDS-inducing infection of a new host,...


    pub_type: 杂志文章


    authors: Courgnaud V,Saurin W,Villinger F,Sonigo P

    更新日期:1998-07-20 00:00:00