Coconut tinangaja viroid: sequence homology with coconut cadang-cadang viroid and other potato spindle tuber viroid related RNAs.


:The nucleotide sequence of two variants of coconut tinangaja viroid (CTiV) were obtained. Both sequence variants are 254 nucleotide residues in size but differ in sequence at two positions. In comparisons with other viroids, the sequences and proposed secondary structure of CTiV show most homology with the 246 nucleotide residue variant of coconut cadang-cadang viroid (CCCV (246]. Several regions throughout the rod-like molecules of CTiV show significant structural and sequence homology with other RNAs related to potato spindle tuber viroid. These homologies include a centrally positioned uridine bulged G:C helix and a 17 nucleotide residue sequence found in common with hop stunt viroid in the left-hand end loop of both viroids.






Keese P,Osorio-Keese ME,Symons RH




Has Abstract


1988-02-01 00:00:00














  • Gene 61.3 of bacteriophage T4 is the spackle gene.

    abstract::The bacteriophage T4 e gene encodes lysozyme (e-lysozyme), which releases progeny phage after normal infection of Escherichia coli cells. A mutation in the spackle gene suppresses the defect in e-lysozyme (Emrich, 1968). The spackle gene was mapped between genes 41 and 61, but its precise location has not previously b...


    pub_type: 杂志文章


    authors: Kai T,Ueno H,Otsuka Y,Morimoto W,Yonesaki T

    更新日期:1999-08-01 00:00:00

  • Carboxy-fluorescein diacetate, succinimidyl ester labeled papillomavirus virus-like particles fluoresce after internalization and interact with heparan sulfate for binding and entry.

    abstract::Human papillomaviruses (HPVs) infect epithelial cells and are associated with genital carcinoma. Most epithelial cell lines express cell-surface glycosaminoglycans (GAGs) usually found attached to the protein core of proteoglycans. Our aim was to study how GAGs influenced HPV entry. Using a human keratinocyte cell lin...


    pub_type: 杂志文章


    authors: Drobni P,Mistry N,McMillan N,Evander M

    更新日期:2003-05-25 00:00:00

  • Classical swine H1N1 influenza viruses confer cross protection from swine-origin 2009 pandemic H1N1 influenza virus infection in mice and ferrets.

    abstract::The hemagglutinin of the 2009 pandemic H1N1 influenza virus is a derivative of and is antigenically related to classical swine but not to seasonal human H1N1 viruses. We compared the A/California/7/2009 (CA/7/09) virus recommended by the WHO as the reference virus for vaccine development, with two classical swine infl...


    pub_type: 杂志文章


    authors: Min JY,Chen GL,Santos C,Lamirande EW,Matsuoka Y,Subbarao K

    更新日期:2010-12-05 00:00:00

  • The release of bluetongue virus from infected cells and their superinfection by progeny virus.

    abstract::Immunoelectron microscopy using an anti-VP2 monoclonal antibody complexed to colloidal gold has been used to study the mechanism of bluetongue virus (BTV) release from infected cells. Examination of the BTV-infected cell surface revealed that viruses are released both as enveloped particles, by budding through the pla...


    pub_type: 杂志文章


    authors: Hyatt AD,Eaton BT,Brookes SM

    更新日期:1989-11-01 00:00:00

  • Functional domains in the feline immunodeficiency virus nucleocapsid protein.

    abstract::Retroviral nucleocapsid (NC) proteins are small Gag-derived products containing one or two zinc finger motifs that mediate genomic RNA packaging into virions. In this study, we addressed the role of the feline immunodeficiency virus (FIV) NC protein in the late stages of virus replication by analyzing the assembly phe...


    pub_type: 杂志文章


    authors: Manrique ML,Rauddi ML,González SA,Affranchino JL

    更新日期:2004-09-15 00:00:00

  • Norovirus classification and proposed strain nomenclature.

    abstract::Without a virus culture system, genetic analysis becomes the principal method to classify norovirus (NoV) strains. Currently, classification of NoV strains beneath the species level has been based on sequences from different regions of the viral genome. As a result, the phylogenetic insights of some virus were not app...


    pub_type: 杂志文章


    authors: Zheng DP,Ando T,Fankhauser RL,Beard RS,Glass RI,Monroe SS

    更新日期:2006-03-15 00:00:00

  • Rapid establishment of stable retroviral packaging cells and recombinant susceptible target cell lines employing novel transposon vectors derived from Sleeping Beauty.

    abstract::Viral vector particles derived from murine leukemia virus (MLV) mediate highly efficient stable gene transfer used in gene therapeutic approaches and in the generation of transgenic cell lines. However, the establishment of stable viral packaging cells (VPCs) is a time-consuming challenge. To overcome this limitation,...


    pub_type: 杂志文章


    authors: Berg K,Schäfer VN,Bartnicki N,Eggenschwiler R,Cantz T,Stitz J

    更新日期:2019-05-01 00:00:00

  • High viral load and CD4 lymphopenia in rhesus and cynomolgus macaques infected by a chimeric primate lentivirus constructed using the env, rev, tat, and vpu genes from HIV-1 Lai.

    abstract::Chimeric primate lentiviruses composed of SIV and HIV genes may allow the analysis of the role of these discrete HIV genes in viral pathogenesis in macaque monkeys. We have constructed a chimeric virus in which the env, rev, tat, and vpu genes of HIV-1 Lai replace the env, rev, and tat genes of the SIVmac239 genome. T...


    pub_type: 杂志文章


    authors: Dunn CS,Beyer C,Kieny MP,Gloeckler L,Schmitt D,Gut JP,Kirn A,Aubertin AM

    更新日期:1996-09-15 00:00:00

  • DNA binding activity is required for EBNA 1-dependent transcriptional activation and DNA replication.

    abstract::Epstein-Barr virus nuclear antigen 1 (EBNA 1) has been shown to be a sequence-specific DNA binding protein that is required for the replication of episomal elements carrying the viral origin of DNA replication, oriP, as well as for the activation of a specific transcriptional enhancer. We have constructed and analyzed...


    pub_type: 杂志文章


    authors: Polvino-Bodnar M,Schaffer PA

    更新日期:1992-04-01 00:00:00

  • Region of Nipah virus C protein responsible for shuttling between the cytoplasm and nucleus.

    abstract::Nipah virus (NiV) causes severe encephalitis in humans, with high mortality. NiV nonstructural C protein (NiV-C) is essential for its pathogenicity, but its functions are unclear. In this study, we focused on NiV-C trafficking in cells and found that it localizes predominantly in the cytoplasm but partly in the nucleu...


    pub_type: 杂志文章


    authors: Horie R,Yoneda M,Uchida S,Sato H,Kai C

    更新日期:2016-10-01 00:00:00

  • Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V.

    abstract::Efavirenz resistance during HIV-1 treatment failure is usually associated with the reverse transcriptase mutation K103N. L100I, V108I, or P225H can emerge after K103N and increase its level of efavirenz resistance. K103N + L100I is the most drug-resistant of the double mutants but is the least common clinically. We hy...


    pub_type: 杂志文章


    authors: Koval CE,Dykes C,Wang J,Demeter LM

    更新日期:2006-09-15 00:00:00

  • In vivo analysis of the cell cycle dependent association of the bovine papillomavirus E2 protein and ChlR1.

    abstract::It has been shown that the genomes of episomally maintained DNA viruses are tethered to host cell chromosomes during cell division, facilitating maintenance in dividing cells. The papillomavirus E2 protein serves this mechanism of viral genome persistence by simultaneously associating with chromatin and the viral geno...


    pub_type: 杂志文章


    authors: Feeney KM,Saade A,Okrasa K,Parish JL

    更新日期:2011-05-25 00:00:00

  • Drosophila miR-956 suppression modulates Ectoderm-expressed 4 and inhibits viral replication.

    abstract::Small non-coding microRNAs (miRNAs) can modulate the outcome of virus infection. Here we explore the role of miRNAs in insect-virus interactions, in vivo, using the natural Drosophila melanogaster-Drosophila C virus (DCV) model system. Comparison of the miRNA expression profiles in DCV-infected and uninfected flies sh...


    pub_type: 杂志文章


    authors: Monsanto-Hearne V,Tham ALY,Wong ZS,Asgari S,Johnson KN

    更新日期:2017-02-01 00:00:00

  • The N-terminal domain of the vaccinia virus E3L-protein is required for neurovirulence, but not induction of a protective immune response.

    abstract::Encephalitis is a rare, but serious complication from vaccination against smallpox using replication competent strains of vaccinia virus. In this report we describe mutants of vaccinia virus, containing N-terminal deletions of the vaccinia virus interferon resistance gene, E3L, that are attenuated for neuropathogenesi...


    pub_type: 杂志文章


    authors: Brandt T,Heck MC,Vijaysri S,Jentarra GM,Cameron JM,Jacobs BL

    更新日期:2005-03-15 00:00:00

  • The role of proximal and distal sequence variations in the presentation of an immunodominant CTL epitope encoded by the ecotropic AK7 MuLV.

    abstract::An emv-14-derived, replication-competent ecotropic murine leukemia virus [MuLV], designated AK7, was previously cloned from the AKXL-5 recombinant inbred mouse strain and partially characterized. While genetically encoding for an envelope-derived immunodominant CTL epitope [KSPWFTTL] located in the transmembrane regio...


    pub_type: 杂志文章


    authors: Kim V,Green WR

    更新日期:1997-09-29 00:00:00

  • Mouse mammary tumor virus uses mouse but not human transferrin receptor 1 to reach a low pH compartment and infect cells.

    abstract::Mouse mammary tumor virus (MMTV) is a pH-dependent virus that uses mouse transferrin receptor 1 (TfR1) for entry into cells. Previous studies demonstrated that MMTV could induce pH 5-dependent fusion-from-with of mouse cells. Here we show that the MMTV envelope-mediated cell-cell fusion requires both the entry recepto...


    pub_type: 杂志文章


    authors: Wang E,Obeng-Adjei N,Ying Q,Meertens L,Dragic T,Davey RA,Ross SR

    更新日期:2008-11-25 00:00:00

  • TLR5 stimulation is sufficient to trigger reactivation of latent HIV-1 provirus in T lymphoid cells and activate virus gene expression in central memory CD4+ T cells.

    abstract::When effector CD4+ T cells carrying integrated HIV-1 proviruses revert back to a resting memory state, the virus can remain silent in those cells for years. Following re-exposure to the nominal antigen or in response to other stimuli (e.g. pro-inflammatory cytokines), these cells can begin to produce virus. Here we de...


    pub_type: 杂志文章


    authors: Thibault S,Imbeault M,Tardif MR,Tremblay MJ

    更新日期:2009-06-20 00:00:00

  • Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed macaques.

    abstract::Previous studies have shown that the transmembrane (TM) domain of the subtype B Vpu enhances virion release from cells and some studies have shown that this domain may form an oligomeric structure with properties of an ion channel. To date, no studies have been performed to assess the role of this domain in virus path...


    pub_type: 杂志文章


    authors: Hout DR,Gomez ML,Pacyniak E,Gomez LM,Inbody SH,Mulcahy ER,Culley N,Pinson DM,Powers MF,Wong SW,Stephens EB

    更新日期:2005-08-15 00:00:00

  • Protein S and Gas6 induce efferocytosis of HIV-1-infected cells.

    abstract::Efferocytosis, the phagocytic clearance of apoptotic cells, can provide host protection against certain types of viruses by mediating phagocytic clearance of infected cells undergoing apoptosis. It is known that HIV-1 induces apoptosis and HIV-1-infected cells are efferocytosed by macrophages, although its molecular m...


    pub_type: 杂志文章


    authors: Chua BA,Ngo JA,Situ K,Ramirez CM,Nakano H,Morizono K

    更新日期:2018-02-01 00:00:00

  • Characterization of the polypeptides and determination of genome coding assignments of an aquareovirus.

    abstract::Proteins of an aquareovirus isolated from striped bass (SBR strain) were examined. Twelve viral-specific proteins ranging in molecular weight from approximately 130 to 15 kDa were identified in infected cells. Purified virions and infected cell lysates were used to characterize the structural and nonstructural protein...


    pub_type: 杂志文章


    authors: Subramanian K,McPhillips TH,Samal SK

    更新日期:1994-11-15 00:00:00

  • Characterization of intranuclear capsids made by ts morphogenic mutants of HSV-1.

    abstract::We have characterized capsids made by seven temperature-sensitive (ts) mutants of HSV-1 previously shown to be defective in viral DNA processing and packaging at the nonpermissive temperature (NPT). The empty capsids isolated from mutant-infected cells at the NPT were devoid of DNA, cosedimented in sucrose with wt B c...


    pub_type: 杂志文章


    authors: Sherman G,Bachenheimer SL

    更新日期:1988-04-01 00:00:00

  • Multiple small RNA species and the viroid hypothesis for the sunblotch disease of avocado.

    abstract::Multiple RNA species (ASV(1-5)) ranging in size from about 61,000 to 185,000 daltons have been detected in association with sunblotch disease of avocado. The predominant species, ASV(5), with a molecular weight of 61,000 accumulates to concentration approaching 5 S RNA. All RNA species are detected in extracts from sy...


    pub_type: 杂志文章


    authors: Semancik JS,Desjardins PR

    更新日期:1980-07-15 00:00:00

  • Analysis of human papillomavirus type 16 polypeptides in transformed primary cells.

    abstract::The close association between human papillomavirus type 16 and cervical cancer implies some role for the virus in the development of this cancer. It has been demonstrated that HPV-16 DNA sequences in the presence of activated ras are capable of transforming primary baby rat kidney cells. This communication describes t...


    pub_type: 杂志文章


    authors: Banks L,Crawford L

    更新日期:1988-07-01 00:00:00

  • Expression and glycosylation of the respiratory syncytial virus G protein in Saccharomyces cerevisiae.

    abstract::A cDNA encoding the entire amino acid sequence of the G glycoprotein of respiratory syncytial virus (RSV) was inserted into a yeast-Escherichia coli shuttle vector such that expression of the virus gene was regulated by the yeast GAL1 promoter. Transformation of Saccharomyces cerevisiae with the vector led to the form...


    pub_type: 杂志文章


    authors: Ding MX,Wen DZ,Schlesinger MJ,Wertz GW,Ball LA

    更新日期:1987-08-01 00:00:00

  • Detection of subgenomic cDNAs and mapping of feline foamy virus mRNAs reveals complex patterns of transcription.

    abstract::Feline foamy virus (FeFV) belongs to the group of spumaretroviruses that contain in addition to gag, pol, and env accessory genes collectively called bel genes. Primate FVs have been shown to utilize internal promoters in addition to the 5' LTR promoters. In contrast to other known retroviruses, the FV pol genes are e...


    pub_type: 杂志文章


    authors: Bodem J,Löchelt M,Delius H,Flügel RM

    更新日期:1998-05-10 00:00:00

  • Genetic determinants of host-specificity in bipartite geminivirus DNA A components.

    abstract::Geminiviruses are small, ssDNA-containing plant viruses. Bean golden mosaic virus (BGMV) and tomato golden mosaic virus (TGMV) have bipartite genomes, the components of which are designated A and B. Although they are closely related, BGMV and TGMV nevertheless exhibit distinct host-specific phenotypes, with BGMV being...


    pub_type: 杂志文章


    authors: Gillette WK,Meade TJ,Jeffrey JL,Petty IT

    更新日期:1998-11-25 00:00:00

  • Mutations increasing exposure of a receptor binding site epitope in the soluble and oligomeric forms of the caprine arthritis-encephalitis lentivirus envelope glycoprotein.

    abstract::The caprine arthritis-encephalitis (CAEV) and ovine maedi-visna (MVV) viruses are resistant to antibody neutralization, a feature shared with all other lentiviruses. Whether the CAEV gp135 receptor binding site(s) (RBS) in the functional surface envelope glycoprotein (Env) is protected from antibody binding, allowing ...


    pub_type: 杂志文章


    authors: Hötzel I,Cheevers WP

    更新日期:2005-09-01 00:00:00

  • Capsid protein and helper component-proteinase function as potyvirus cell-to-cell movement proteins.

    abstract::The role of bean common mosaic necrosis potyvirus (BCMNV) and lettuce mosaic potyvirus (LMV) proteins was investigated in terms of their capacity to function as viral movement proteins (MPs). Using Escherichia coli-expressed proteins and microinjection techniques, direct evidence was obtained that both the potyviral c...


    pub_type: 杂志文章


    authors: Rojas MR,Zerbini FM,Allison RF,Gilbertson RL,Lucas WJ

    更新日期:1997-10-27 00:00:00

  • Nucleotide sequence and deduced amino acid sequence of the nonstructural proteins of dengue type 2 virus, Jamaica genotype: comparative analysis of the full-length genome.

    abstract::The sequence of the 5'-end of the genome of dengue 2 (Jamaica genotype) virus has been previously reported (V. Deubel, R. M. Kinney, and D. W. Trent, 1986, Virology 155, 365-377). We have now cloned and sequenced the remaining 75% of the genomic RNA that encodes the nonstructural proteins. The complete genome is 10,72...


    pub_type: 杂志文章


    authors: Deubel V,Kinney RM,Trent DW

    更新日期:1988-07-01 00:00:00

  • Inhibition of vaccinia virus replication by N-(phosphonoacetyl)-L-aspartate: differential effects on viral gene expression result from a reduced pyrimidine nucleotide pool.

    abstract::The replication of vaccinia virus was reduced by 3 logs in cells that had been treated before and during infection with a concentration of N-(phosphonoacetyl)-L-aspartate (PALA) which lowered the UTP and CTP to 5 and 20% of controls, respectively, without affecting cell viability. The antiviral activity of PALA was re...


    pub_type: 杂志文章


    authors: Katsafanas GC,Grem JL,Blough HA,Moss B

    更新日期:1997-09-15 00:00:00