Inhibition of host cellular ribonucleic acid synthesis by glycoprotein of mumps virus.

abstract：:During respiratory syncytial virus (RSV) infection there is a close physical interaction between the filamentous actin (F-actin) and the virus, involving both inclusion bodies and the virus filaments. This interaction appears to occur relatively early in the replication cycle, and can be detected from 8 h post-infecti...

journal_title：Virology

authors： Jeffree CE,Brown G,Aitken J,Su-Yin DY,Tan BH,Sugrue RJ

更新日期：2007-12-20 00:00:00

abstract：:The enveloped virions of two strains of a granulosis virus, a synergistic Hawaiian (GVH) and a nonsynergistic Oregonian (GVO) strain which infect the armyworm, Pseudaletia unipuncta, were liberated from their capsules with 0.02 N NaOH and purified by filtration through membrane filters. The envelopes were solubilized ...

journal_title：Virology

authors： Yamamoto T,Tanada Y

更新日期：1979-04-15 00:00:00

abstract：:During the productive phase of chronic hepadnaviral infections, virion DNA synthesis occurs in the cytoplasm of the infected hepatocyte, but viral RNA is synthesized in the nucleus, apparently from a covalently closed, circular (CCC) viral DNA. J. Tuttleman, C. Pourcel, and J. Summers (1986a, Cell 47, 451-460) have sh...

journal_title：Virology

authors： Wu TT,Coates L,Aldrich CE,Summers J,Mason WS

更新日期：1990-03-01 00:00:00

abstract：:When hemagglutinin (HA) and neuraminidase (NA) are presented together on an intact influenza virus particle, the antigens are competitive, with HA dominant over NA in T- and B-cell priming. Immunization with mixtures of purified HA and NA eliminates antigenic competition between HA and NA, as well as between N1-N2 NA ...

journal_title：Virology

authors： Johansson BE,Kilbourne ED

更新日期：1996-11-01 00:00:00

abstract：:NF-kappaB comprises a family of transcription factors that regulate key immune processes. In this study, the effects of orthopoxvirus infection upon the activation of NF-kappaB were examined. During the early phase of infection, cowpox virus can inhibit the induction of NF-kappaB-regulated gene expression by interferi...

journal_title：Virology

authors： Oie KL,Pickup DJ

更新日期：2001-09-15 00:00:00

abstract：:The heptauridine tract at each gene end and intergenic region (IGR) at the gene junctions of vesicular stomatitis virus (VSV) have effects on synthesis of the downstream mRNA, independent of their respective roles in termination of the upstream mRNA. To investigate the role of the U tract and the IGR in downstream gen...

journal_title：Virology

authors： Hinzman EE,Barr JN,Wertz GW

更新日期：2008-10-25 00:00:00

abstract：:We have used a yeast two-hybrid system to show that human papillomavirus E7 proteins can form oligomeric complexes in vivo. The carboxyl-terminal cysteine-rich metal-binding domain is critical for this activity although amino-terminal sequences also contribute to oligomerization. Our experiments also reveal that E7 po...

journal_title：Virology

authors： Clemens KE,Brent R,Gyuris J,Münger K

更新日期：1995-12-01 00:00:00

abstract：:Clade 2.3.4.4 H5N8 highly pathogenic avian influenza viruses (HPAIVs) have spread worldwide. Phylogenetic analysis identified two genetic groups of the H5N8 HPAIVs in South Korea; group A evolved further into four subgroups. Here, we examined the zoonotic potential, both in vivo and in vitro, of genetically distinct s...

journal_title：Virology

authors： Lee YN,Lee EK,Song BM,Heo GB,Woo SH,Cheon SH,Lee YJ

更新日期：2018-03-01 00:00:00

abstract：:Previously different authors described various flavivirus mutants with high affinity to cell glycosaminoglycans and low neuroinvasiveness in mice that were obtained consequently passages in cell cultures or in ticks. In present study the analysis of TBEV isolates has shown existence of GAG-binding variants in natural ...

journal_title：Virology

authors： Kozlovskaya LI,Osolodkin DI,Shevtsova AS,Romanova LIu,Rogova YV,Dzhivanian TI,Lyapustin VN,Pivanova GP,Gmyl AP,Palyulin VA,Karganova GG

更新日期：2010-03-15 00:00:00

abstract：:The baculovirus-insect cell system is used routinely for foreign glycoprotein production, but the precise nature of the N-glycosylation pathway in this system remains unclear. Some studies indicate that these cells cannot process N-linked oligosaccharides to complex forms containing outer-chain galactose and sialic ac...

journal_title：Virology

authors： Jarvis DL,Finn EE

更新日期：1995-10-01 00:00:00

abstract：:A nonaphid transmissible (NAT) variant of tobacco vein mottling virus (TVMV) was used to test the hypothesis that the viral coat protein (CP) plays a role in determining aphid transmissibility. Comparison of the nucleotide sequences in the coat protein cistron of an aphid transmissible isolate (TVMV-AT) with that of T...

journal_title：Virology

authors： Atreya CD,Raccah B,Pirone TP

更新日期：1990-09-01 00:00:00

abstract：:In reporter-based transient expression systems, we characterized simian immunodeficiency virus from a chimpanzee (SIVCPZ), with special reference to the human immunodeficiency virus type 1 (HIV-1). SIVCPZ was not equally activated by tat and rev transactivators derived from representative primate lentiviruses. HIV-1 a...

journal_title：Virology

authors： Sakuragi J,Sakai H,Sakuragi S,Shibata R,Wain-Hobson S,Hayami M,Adachi A

更新日期：1992-07-01 00:00:00

abstract：:In this study, we investigated the autoimmune response in rabbit ovaries following infection with a recombinant myxoma virus expressing rabbit zona pellucida protein B (MV-ZPB). A specific IgG antibody response to ZPB was elicited in the serum of infected rabbits and the antibody strongly bound to the zona pellucida o...

journal_title：Virology

authors： Gu W,Holland M,Janssens P,Seamark R,Kerr P

更新日期：2004-01-20 00:00:00

abstract：:Recombinant human immunodeficiency virus type-1 (HIV-1)-like gag-env particles produced in mammalian cells were inoculated into two New Zealand white rabbits. In parallel, two control rabbits were inoculated with the homologous HIV-1 virions inactivated by ultra violet light (uv) and psoralen treatments. The humoral a...

journal_title：Virology

authors： Haffar OK,Smithgall MD,Moran PA,Travis BM,Zarling JM,Hu SL

更新日期：1991-08-01 00:00:00

abstract：:Flock house virus (FHV) encodes a suppressor protein B2 to overcome antiviral RNA silencing during infection. Biochemical analyses have shown that a homodimer of B2 binds to double-stranded RNA to inhibit dicer-mediated cleavage of dsRNA and incorporation of small interfering RNAs into the RNA-induced silencing comple...

journal_title：Virology

authors： Seo JK,Kwon SJ,Rao AL

更新日期：2012-10-25 00:00:00

abstract：:The spike (S) and hemagglutinin/esterase (HE) of bovine coronavirus (BCV) are the two envelope proteins that recognize the same receptor-determinant of 9-O-acetylneuraminic acid on host cells. However, the precise and relative roles of the two proteins in BCV infectivity remain elusive. To unequivocally determine thei...

journal_title：Virology

authors： Popova R,Zhang X

更新日期：2002-03-01 00:00:00

abstract：:The genome of Lelystad virus (LV), a positive-strand RNA virus, is 15 kb in length and contains 8 open reading frames (ORFs) that encode putative viral proteins. ORFs 2 to 7 were cloned in plasmids downstream of the Sp6 RNA polymerase promoter, and the translation of transcripts generated in vitro yielded proteins tha...

journal_title：Virology

authors： Meulenberg JJ,Petersen-den Besten A,De Kluyver EP,Moormann RJ,Schaaper WM,Wensvoort G

更新日期：1995-01-10 00:00:00

abstract：:To gain new insights regarding the role of Ku, the DNA-PK DNA-binding component, during lentiviral DNA integration, we have investigated the HIV-1 replication in Ku80-depleted human cells. CEM4fx cells underexpressing the Ku80 factor were selected after transduction by a retroviral vector expressing the Ku80 full-leng...

journal_title：Virology

authors： Jeanson L,Subra F,Vaganay S,Hervy M,Marangoni E,Bourhis J,Mouscadet JF

更新日期：2002-08-15 00:00:00

abstract：:Human Adenovirus Type 4 (HAdV-4) is responsible for epidemic outbreaks of Acute Respiratory Disease (especially in military recruits), and is known to cause significant morbidity with several reported cases of mortality. However, we do not understand why this serotype causes such high morbidity, and have little insigh...

journal_title：Virology

authors： Hartman ZC,Appledorn DM,Serra D,Glass O,Mendelson TB,Clay TM,Amalfitano A

更新日期：2008-05-10 00:00:00

abstract：:Mutants of the influenza virus A/seal/Mass/1/80 (H7N7) are described which contain an insertion of 60 nucleotides in the hemagglutinin (HA) gene, derived most probably by recombination between the HA gene and the nucleoprotein gene of the same virus. The nonhomologous RNA recombination resulted in an enhanced hemagglu...

journal_title：Virology

authors： Orlich M,Gottwald H,Rott R

更新日期：1994-10-01 00:00:00

abstract：:To begin to map functional domains of the Sendai P-L RNA polymerase complex we wanted to characterize the P binding site on the Sendai L protein. Analysis of in vitro and in vivo P-L polymerase complex formation with carboxyl-truncations of the L protein showed that the N-terminal half of the protein was required. Sit...

journal_title：Virology

authors： Chandrika R,Horikami SM,Smallwood S,Moyer SA

更新日期：1995-11-10 00:00:00

abstract：:Using high resolution electron microscopic autoradiography and immunocytochemistry with monoclonal antibodies against poliovirus proteins of the P2 genomic region, the location of these proteins in respect to the virus-induced vesicle formation and the viral RNA synthesis was followed during the viral replication cycl...

journal_title：Virology

authors： Bienz K,Egger D,Pasamontes L

更新日期：1987-09-01 00:00:00

abstract：:A full-size cloned cDNA copy of the rotavirus gene encoding the structural neutralization glycoprotein (VP7) of Nebraska calf diarrhea virus (NCDV), a strain recently shown to be effective as a vaccine in children, has been sequenced. Comparison of the deduced amino acid sequence of NCDV (serotype 6) VP7 with that of ...

journal_title：Virology

authors： Glass RI,Keith J,Nakagomi O,Nakagomi T,Askaa J,Kapikian AZ,Chanock RM,Flores J

更新日期：1985-03-01 00:00:00

abstract：:Old world hantaviruses, causing hemorrhagic fever with renal syndrome (HFRS), still present a public health problem in Asia and Eastern Europe. The majority of cases has been recorded in China. The aim of our study was to generate human recombinant neutralizing antibodies to a hantavirus by phage display technology. T...

journal_title：Virology

authors： Koch J,Liang M,Queitsch I,Kraus AA,Bautz EK

更新日期：2003-03-30 00:00:00

abstract：:cDNA clones encoding the envelope glycoprotein E1 of rubella virus (RV) were altered by site-directed mutagenesis at consensus sites for addition of N-linked glycans. The resulting plasmids were introduced into COS cells and the mutant E1 proteins were analyzed by indirect immunofluorescence, radioimmunoprecipitation,...

journal_title：Virology

authors： Hobman TC,Qiu ZY,Chaye H,Gillam S

更新日期：1991-04-01 00:00:00

abstract：:Sindbis virus (SINV) induces inflammatory and vasoactive responses that are associated with rash and arthritis in human infections. The mechanisms underlying infection-associated microvasculopathy are still unknown. We investigated whether endothelial cells infected by SINV are differentially responsive to bradykinin ...

journal_title：Virology

authors： Rust NM,Papa MP,Scovino AM,da Silva MM,Calzavara-Silva CE,Marques ET Jr,Peçanha LM,Scharfstein J,Arruda LB

更新日期：2012-01-05 00:00:00

abstract：:A major 135-kDa DNA binding protein (mDBP) encoded by the BALF2 open reading frame of Epstein-Barr Virus (EBV) is known to be an essential protein for the induction of the lytic cycle. The present investigation was carried out to know whether this protein forms a complex in vivo with other viral DNA binding proteins (...

journal_title：Virology

authors： Zeng Y,Middeldorp J,Madjar JJ,Ooka T

更新日期：1997-12-22 00:00:00

abstract：:Using reverse genetics methods, we constructed three different transfectant influenza A viruses encoding an Ld-restricted, nine amino-acid-long fragment, corresponding to amino-acid residues 876-884, of beta-galactosidase (beta-gal). Sequences encoding this epitope were nested within the hemagglutinin (HA) or neuramin...

journal_title：Virology

authors： Restifo NP,Surman DR,Zheng H,Palese P,Rosenberg SA,García-Sastre A

更新日期：1998-09-15 00:00:00

abstract：:Major efforts have been put forth for the development of effective rotavirus vaccines including transgenic plant vaccines. Previous studies have reported that rotavirus VP7 maintains its neutralizing immunity when it is transformed into the potato genome. The present study was aimed at investigating the hereditary sta...

journal_title：Virology

authors： Li JT,Fei L,Mou ZR,Wei J,Tang Y,He HY,Wang L,Wu YZ

更新日期：2006-12-05 00:00:00

abstract：:Infectious bronchitis virus (IBV) produces six subgenomic (sg) mRNAs, each containing a 64 nucleotide (nt) leader sequence, derived from the 5' end of the genome by a discontinuous process. Several putative functional domains such as a papain-like proteinase (PL(pro)), main protease (M(pro)), RNA-dependent RNA polymer...

journal_title：Virology

authors： Mondal SP,Cardona CJ

更新日期：2004-06-20 00:00:00