Interleukin-6 and type 1 interferons inhibit varicella zoster virus replication in human neurons.

abstract：:Natural antibodies to gp41 inhibit HIV-1 replication through the recognition of two different regions, corresponding to the leucine zipper motif in the HR1 alpha-helix and to another motif within HR2 region, hosting 2F5 and 4E10 epitope. This study aimed at reproducing such protective responses through VLP vaccination...

journal_title：Virology

authors： Pastori C,Tudor D,Diomede L,Drillet AS,Jegerlehner A,Röhn TA,Bomsel M,Lopalco L

更新日期：2012-09-15 00:00:00

abstract：:A series of carboxy- and amino-terminal deletion mutations in the movement protein (MP) gene of tobacco mosaic virus (TMV) were ligated into a cloned TMV cDNA deleted for the endogenous MP gene. RNA transcripts were produced in vitro from clones carrying the various mutated MP genes. The effect of the deletion mutatio...

journal_title：Virology

authors： Gafny R,Lapidot M,Berna A,Holt CA,Deom CM,Beachy RN

更新日期：1992-04-01 00:00:00

abstract：:Human papillomavirus type 16 (HPV-16) E2 protein negatively regulates transcription of the E6 and E7 genes. This study was done to test the hypothesis that methylation of the HPV 16 long control region (LCR) is overrepresented among cervical cancer (CaCx) cases compared to cytologically normal controls harboring intac...

journal_title：Virology

authors： Bhattacharjee B,Sengupta S

更新日期：2006-10-25 00:00:00

abstract：:In this study, we analyzed the replication and budding sites of severe acute respiratory syndrome coronavirus (SARS-CoV) at early time points of infection. We detected cytoplasmic accumulations containing the viral nucleocapsid protein, viral RNA and the non-structural protein nsp3. Using EM techniques, we found that ...

journal_title：Virology

authors： Stertz S,Reichelt M,Spiegel M,Kuri T,Martínez-Sobrido L,García-Sastre A,Weber F,Kochs G

更新日期：2007-05-10 00:00:00

abstract：:Previously our laboratory constructed an HIV-1 which stably maintained a primer binding site (PBS) complementary to tRNA(His) by mutating the region of the provirus within U5 postulated to interact with the anticodon of tRNA(His) (J. Wakefield, S-M Kang, and C. D. Morrow, 1996, J. Virol, 70, 966-975). From the analysi...

journal_title：Virology

authors： Li Y,Zhang Z,Kang SM,Buescher JL,Morrow CD

更新日期：1997-11-24 00:00:00

abstract：:Stress granule (SG)-like antiviral granules (AVG) had been found in some vaccinia virus infection conditions and shown to repress translation. Similar RNA granules are also associated with translational inhibition and poxvirus restriction mediated by the host restriction factor SAMD9, but their function is less clear....

journal_title：Virology

authors： Meng X,Xiang Y

更新日期：2019-03-01 00:00:00

abstract：:In reporter-based transient expression systems, we characterized simian immunodeficiency virus from a chimpanzee (SIVCPZ), with special reference to the human immunodeficiency virus type 1 (HIV-1). SIVCPZ was not equally activated by tat and rev transactivators derived from representative primate lentiviruses. HIV-1 a...

journal_title：Virology

authors： Sakuragi J,Sakai H,Sakuragi S,Shibata R,Wain-Hobson S,Hayami M,Adachi A

更新日期：1992-07-01 00:00:00

abstract：:We described a simple method to introduce site-specific mutations into region E3 of adenovirus (Ad). Mutations are made in cloned Ad2 EcoRI-D (map position 76-83), then ligated between Ad5 EcoRI-A (map position 0-76) and EcoRI-B (map position 83-100) to complete the viral genome. We have used this method to isolate a ...

journal_title：Virology

authors： Wold WS,Deutscher SL,Takemori N,Bhat BM,Magie SC

更新日期：1986-01-15 00:00:00

abstract：:The amino acid sequence of BMV (brome mosaic virus) coat protein is presented and compared with the sequence derived from RNA structure. Apart from removal of the N-terminal methionine residue and acetylation of the following serine residue, no post-translational modifications occur. ...

journal_title：Virology

authors： Moosic JP,McKean DJ,Shih DS,Kaesberg P

更新日期：1983-09-01 00:00:00

abstract：:We test the hypothesis that the translation machinery in cells infected by influenza A virus efficiently translates only mRNAs that possess the influenza viral 5' untranslated region (5'-UTR) by introducing mRNAs directly into the cytoplasm of infected cells. This strategy avoids effects due to the inhibition of the n...

journal_title：Virology

authors： Cassetti MC,Noah DL,Montelione GT,Krug RM

更新日期：2001-10-25 00:00:00

abstract：:We have previously demonstrated that the bZIP transcription factor CREB-2, also called ATF-4, trans-activates, in association with the viral protein Tax, the human T-cell leukemia virus type I (HTLV-I) promoter. In this study, we have examined whether CREB-2 acetylation affects transcriptional activation mediated by T...

journal_title：Virology

authors： Gachon F,Devaux C,Mesnard JM

更新日期：2002-08-01 00:00:00

abstract：:The nucleotide sequence of the P gene of human parainfluenza virus type 1 (hPIV1) strain C35 was determined directly from genomic viral RNA and by molecular cloning. The gene contained 1893 nucleotides. Four open reading frames (ORF) capable of encoding a P protein (568 amino acids; M(r) = 64,784), a C' protein (219 a...

journal_title：Virology

authors： Power UF,Ryan KW,Portner A

更新日期：1992-07-01 00:00:00

abstract：:The retroviral cyclin protein (rv-cyclin) of walleye dermal sarcoma virus contains two known functional domains, a cyclin box motif and a carboxy terminal transcription activation domain (AD). The AD contacts TATA-binding protein-associated factor 9 (TAF9), and this action is necessary for both positive and negative r...

journal_title：Virology

authors： Quackenbush SL,Linton A,Brewster CD,Rovnak J

更新日期：2009-03-30 00:00:00

abstract：:Chlorella virus PBCV-1 encodes two putative chitinase genes, a181/182r and a260r, and one chitosanase gene, a292l. The three genes were cloned and expressed in Escherichia coli. The recombinant A181/182R protein has endochitinase activity, recombinant A260R has both endochitinase and exochitinase activities, and recom...

journal_title：Virology

authors： Sun L,Adams B,Gurnon JR,Ye Y,Van Etten JL

更新日期：1999-10-25 00:00:00

abstract：:Vaccinia virus gene D12L, which lies between nucleotides 14,350 and 13,487 in the HindIII D fragment, is transcribed at early times in infection and is capable of encoding a protein 287 amino acids in length with a predicted molecular mass of 33,331. A polyclonal antiserum was raised in rabbits to a fusion protein con...

journal_title：Virology

authors： Niles EG,Lee-Chen GJ,Shuman S,Moss B,Broyles SS

更新日期：1989-10-01 00:00:00

abstract：:The second smallest subgenomic messenger RNA, mRNA5, of the coronavirus infectious bronchitis virus includes in its "5' unique region" two separate open reading frames (5a and 5b), whose coding function has not so far been established, and thus it may represent a dicistronic messenger RNA. We report here that two poly...

journal_title：Virology

authors： Liu DX,Inglis SC

更新日期：1992-01-01 00:00:00

abstract：:While several studies have shown a role for autophagy in the replication of dengue virus (DENV), these studies have been performed in directly infected cells. However, in severe cases of DENV infection the critical cell in the disease is believed to be monocytes which are poorly infected directly, but are highly susce...

journal_title：Virology

authors： Panyasrivanit M,Greenwood MP,Murphy D,Isidoro C,Auewarakul P,Smith DR

更新日期：2011-09-15 00:00:00

abstract：:Frequent occurrence of woodchuck hepatitis virus DNA (WHV DNA) integration into or in proximity to myc oncogenes and in the win locus of cellular genome in woodchuck hepatocellular carcinomas (HCC) has been described by several authors. We report a further cellular locus as a recurrent target for WHV integration in wo...

journal_title：Virology

authors： Bruni R,Argentini C,D'Ugo E,Giuseppetti R,Ciccaglione AR,Rapicetta M

更新日期：1995-12-01 00:00:00

abstract：:Influenza viruses of the H3N2 subtype similar to Aichi/2/68 and Victoria/3/75 persist in pigs many years after their antigenic counterparts have disappeared from humans (Shortridge et al. (1977). Science 19, 1454-1455). To provide information on the mechanism of conservation of these influenza viruses in pigs, the hem...

journal_title：Virology

authors： Kida H,Shortridge KF,Webster RG

更新日期：1988-01-01 00:00:00

abstract：:Enveloped virus entry occurs when viral and cellular membranes fuse releasing particle contents into the target cell. Human immunodeficiency virus (HIV) entry occurs by cell-free virus or virus transferred between infected and uninfected cells through structures called virological synapses. We developed a high-through...

journal_title：Virology

authors： Esposito AM,Cheung P,Swartz TH,Li H,Tsibane T,Durham ND,Basler CF,Felsenfeld DP,Chen BK

更新日期：2016-03-01 00:00:00

abstract：:The 5'-terminal noncoding region sequences were determined for the genome RNAs of seven strains of St. Louis encephalitis virus (SLEV) and one strain of West Nile virus (WNV) using a single synthetic cDNA primer complementary to the 5'-terminus of the coding region of a strain of WNV RNA. The 5'-terminal sequences obt...

journal_title：Virology

authors： Brinton MA,Dispoto JH

更新日期：1988-02-01 00:00:00

abstract：:The nucleotide sequences of the long terminal repeat (LTR) of simian retroviruses (STLV), which are closely related to human T-cell leukemia virus type I (HTLV-I) were found to be of at least two subgroups: an Asian subtype in macaques and an African subtype in African green monkeys and chimpanzee. The nucleotide sequ...

journal_title：Virology

authors： Watanabe T,Seiki M,Hirayama Y,Yoshida M

更新日期：1986-01-30 00:00:00

abstract：:Monoclonal antibodies (MAb) against an O1 Suisse isolate of FMDV were used to identify epitopes on the virus particle and to determine their relative function. Six major antigenic sites containing one or more epitopes were identified using competition ELISA. An epitope relationship is proposed consisting of a trypsin-...

journal_title：Virology

authors： McCullough KC,Crowther JR,Carpenter WC,Brocchi E,Capucci L,De Simone F,Xie Q,McCahon D

更新日期：1987-04-01 00:00:00

abstract：:While trying to generate a site-directed deletion in the ORF63 latency-associated gene of varicella-zoster virus (VZV) Oka, we constructed a virus with an unexpected rearrangement. The virus has a small deletion in both copies of ORF63 and two copies of a cassette inserted between ORFs 64/65 and 68/69 containing (a) t...

journal_title：Virology

authors： Ambagala AP,Krogmann T,Qin J,Pesnicak L,Cohen JI

更新日期：2010-04-10 00:00:00

abstract：:Friend murine leukemia virus (Fr-MLV) produces unspliced mRNAs, as well as singly-spliced mRNAs by which the Env protein is generated. We investigated the role of the intron within the Fr-MLV gene in Env expression using vectors with serially truncated introns. The up-regulatory regions, the 361-878 and the 5135-5399 ...

journal_title：Virology

authors： Yamamoto N,Takase-Yoden S

更新日期：2009-03-01 00:00:00

abstract：:Bacteriophage T4 tails contain a set of extended protein molecules in the central channel of the tail tube through which the DNA must exit during infection. Treatment of tails with guanidine hydrochloride separates the baseplates, leaving the tail tube and several specific tube-associated proteins. Methods were develo...

journal_title：Virology

authors： Duda RL,Gingery M,Eiserling FA

更新日期：1986-06-01 00:00:00

abstract：:RNA-binding proteins of coronavirus MHV-A59 were identified using an RNA overlay-protein blot assay (ROPBA). The major viral RNA-binding protein in virions and infected cells was the phosphorylated nucleocapsid protein N (50K). A new 140K virus structural protein was identified as a minor RNA-binding protein both in v...

journal_title：Virology

authors： Robbins SG,Frana MF,McGowan JJ,Boyle JF,Holmes KV

更新日期：1986-04-30 00:00:00

abstract：:The protein p10 that forms the connector of phage phi 29, has been produced in Escherichia coli harboring a plasmid that carried the gene coding for this protein. The connector protein is assembled in a 13.4-S oligomer that has an apparent molecular weight of 460,000, suggesting that it is a dodecamer. The purified ol...

journal_title：Virology

authors： Carrascosa JL,Carazo JM,Ibañez C,Santisteban A

更新日期：1985-03-01 00:00:00

abstract：:Antigenic variation is a characteristic feature of lentiviral infection. The SIV/macaque model of AIDS provides an ideal system in which to investigate the molecular basis of antigenic variation. The purpose of this study was to genetically map the nucleotide changes in env that alter the neutralization phenotype of S...

journal_title：Virology

authors： Kinsey NE,Anderson MG,Unangst TJ,Joag SV,Narayan O,Zink MC,Clements JE

更新日期：1996-07-01 00:00:00

abstract：:Human papillomavirus (HPV) DNA is preferentially found in spontaneous abortions, specifically residing in trophoblasts, and transfected HPV-16 DNA replicates and produces progeny in 3A trophoblasts in culture. In this study 3A trophoblasts were shown to display both HPV receptors and infection by HPV-31b and HPV-6 vir...

journal_title：Virology

authors： You H,Liu Y,Agrawal N,Prasad CK,Chiriva-Internati M,Lowery CL,Kay HH,Hermonat PL

更新日期：2003-11-25 00:00:00