Abstract:
:The nucleotide sequences of the long terminal repeat (LTR) of simian retroviruses (STLV), which are closely related to human T-cell leukemia virus type I (HTLV-I) were found to be of at least two subgroups: an Asian subtype in macaques and an African subtype in African green monkeys and chimpanzee. The nucleotide sequence of HTLV-I was found to be included within the divergence among STLV, but showed closer homology (95%) to African subtype STLV than to Asian subtype STLV (90%).
journal_name
Virologyjournal_title
Virologyauthors
Watanabe T,Seiki M,Hirayama Y,Yoshida Mdoi
10.1016/0042-6822(86)90336-3subject
Has Abstractpub_date
1986-01-30 00:00:00pages
385-8issue
2eissn
0042-6822issn
1096-0341journal_volume
148pub_type
杂志文章相关文献
VIROLOGY文献大全abstract::The red clover necrotic mosaic dianthovirus (RCNMV) genome is split between two single-stranded RNA species termed RNA-1 and RNA-2. RNA-2 is required for infection of whole plants but is dispensable for infection and virion formation in protoplasts. We have used full-length cDNA clones of RNA-1 and -2 from which infec...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1993.1004
更新日期:1993-01-01 00:00:00
abstract::We compared the in vitro fidelity of wild-type human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) and the prototype foamy virus (PFV) RT. Both enzymes had similar error rates for single nucleotide substitutions; however, PFV RT did not appear to make errors at specific hotspots, like HIV-1 RT. In a...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2007.05.034
更新日期:2007-10-25 00:00:00
abstract::Certain temperature-sensitive (ts) mutants of murine leukemia virus (MuLV) were observed to be defective in virus assembly. These mutants also accumulated intracellular core protein precursor, Pr65gag, at 39 degrees, the nonpermissive temperature. At 39 degrees, virions released from cells infected with the various ts...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90306-4
更新日期:1984-04-30 00:00:00
abstract::Studies were performed to induce cross-clade neutralizing antibodies (Abs) by testing various combinations of prime and boost constructs that focus the immune response on structurally-conserved epitopes in the V3 loop of HIV-1 gp120. Rabbits were immunized with gp120 DNA containing a V3 loop characterized by the GPGR ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2009.05.039
更新日期:2009-09-15 00:00:00
abstract::The bipartite genomic RNAs of red clover necrotic mosaic virus (RCNMV) lack a 5' cap and a 3' poly(A) tail. RNA1 encodes viral replication proteins, and RNA2 encodes a movement protein (MP). These proteins are translated in a cap-independent manner. We previously identified two cis-acting RNA elements that cooperative...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2017.06.015
更新日期:2017-09-01 00:00:00
abstract::The complete sequence of the genome of the cherry strain of tomato bushy stunt virus (TBSV), a member of the tombusvirus group, was determined. A full-length clone of the genome containing a bacteriophage T7 RNA polymerase promoter was assembled from partial cDNA clones. In vitro transcripts of the genome, either with...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(90)90468-7
更新日期:1990-07-01 00:00:00
abstract::The immortalizing function of the human adenovirus 5 E1A oncoprotein requires efficient localization to the nucleus. In 1987, a consensus monopartite nuclear localization sequence (NLS) was identified at the C-terminus of E1A. Since that time, various experiments have suggested that other regions of E1A influence nucl...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2014.08.014
更新日期:2014-11-01 00:00:00
abstract::Many viruses activate the phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway, thereby modulating diverse downstream signaling pathways associated with antiapoptosis, proliferation, cell cycling, protein synthesis and glucose metabolism, in order to augment their replication. To date, the role of the PI3K-Akt p...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2009.06.007
更新日期:2009-08-15 00:00:00
abstract::Infection of microglial cells by the human immunodeficiency virus (HIV) is supposed to play an important role in the pathogenesis of AIDS-related central nervous system (CNS) complications. So far, however, experimental data about interactions between HIV and ramified microglia from the adult CNS were only occasionall...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1999.0152
更新日期:2000-03-15 00:00:00
abstract::The open reading frame EP153R, located within the EcoRI E' fragment of the African swine fever (ASF) virus genome, is predicted to encode a membrane protein of 153 amino acids that presents significant homology to the N-terminal region of several CD44 molecules. EP153R contains multiple putative sites for N-glycosylat...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1999.0080
更新日期:2000-01-20 00:00:00
abstract::Mouse mammary tumor virus (MMTV) is a pH-dependent virus that uses mouse transferrin receptor 1 (TfR1) for entry into cells. Previous studies demonstrated that MMTV could induce pH 5-dependent fusion-from-with of mouse cells. Here we show that the MMTV envelope-mediated cell-cell fusion requires both the entry recepto...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2008.08.013
更新日期:2008-11-25 00:00:00
abstract::The RNA genomes of cytopathogenic bovine viral diarrhea virus (BVDV) isolates contain insertions highly homologous to cellular sequences. For two of them the insert was identified as ubiquitin coding sequence. The genome of BVDV Osloss contains exactly one ubiquitin gene monomer. In the case of BVDV CP1 the cellular i...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(91)90074-l
更新日期:1991-02-01 00:00:00
abstract::Marek's Disease Virus (MDV) infects chickens via respiratory route and causes lymphomas in internal organs including gastrointestinal tract. MDV infection causes a shift in the gut microbiota composition. However, interactions between the gut microbiota and immune responses against MDV infection are not well understoo...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2020.10.011
更新日期:2021-01-15 00:00:00
abstract::Many plant virus coat proteins have binding sites for divalent cations, particularly calcium. It has been speculated that the purpose of such sites is to ensure that plant viruses release their RNA only in the host cytoplasm which has a low calcium concentration. By comparison to tomato bushy stunt virus, two of the a...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1993.1655
更新日期:1993-12-01 00:00:00
abstract::NS35, a basic protein encoded by gene 8 of SA11 rotavirus, possesses RNA-binding activity and is essential for genome replication. To identify conserved regions in the NS35 gene and its protein product, we determined the nucleotide sequences of the NS35 gene for the mammalian and avian rotaviruses Wa, DS1, SA11 (Patto...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1993.1059
更新日期:1993-02-01 00:00:00
abstract::Mouse LTK- cells (H-2k) were transfected with a series of recombinant plasmids consisting of the herpes simplex virus type 1 thymidine kinase (TK) gene linked to fragments of SV40 DNA coding for portions of SV40 T antigen in pBR322, and TK+ transformants (LTK+) were selected in HAT medium. The TK+ transformants were a...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(83)90259-3
更新日期:1983-07-30 00:00:00
abstract::We used a series of deletion mutations in the 5' untranslated region of the prototype D type retrovirus, Mason-Pfizer Monkey Virus (MPMV), to analyse RNA encapsidation. A region was identified upstream of the major splice donor which reduced particle production but had a proportionally greater effect on RNA packaging....
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.2001.1061
更新日期:2001-09-15 00:00:00
abstract::Pandemic H1N1 influenza A (H1N1pdm) elicits stronger pulmonary inflammation than previously circulating seasonal H1N1 influenza A (sH1N1), yet mechanisms of inflammatory activation in respiratory epithelial cells during H1N1pdm infection are unclear. We investigated host responses to H1N1pdm/sH1N1 infection and virus ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2013.09.022
更新日期:2014-01-05 00:00:00
abstract::In human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) the gag gene encodes the precursor polyprotein Pr55Gag, which is cleaved by the viral protease to produce the major structural proteins. Recently, it has been shown that HIV and SIV gag RNAs contain internal ribosome entry sites (IR...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2006.10.003
更新日期:2007-03-30 00:00:00
abstract::Previously a new small subclass of SV40 large T antigen with a high-binding affinity to living target cells was characterized (J. Lange-Mutschler and R. Henning, 1983, Virology 127, 333-344.) In the present study the external binding process, particularly the tight linkage of T antigen to lipid of the target cells, wa...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90176-4
更新日期:1984-07-30 00:00:00
abstract::The herpes simplex virus type 1 (HSV-1) UL37 open reading frame encodes a 120-kDa late (gamma 1) phosphoprotein in infected cells. Analysis of isolated mature HSV virions and light particles revealed that the UL37 protein is a component of the virion. Detergent solubilization and protease digestion experiments suggest...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1995.1028
更新日期:1995-02-01 00:00:00
abstract::Two noncomplementing vaccinia virus temperature-sensitive mutants, Cts8 and Cts26, were mapped to the A3L gene, which encodes the major virion structural protein, 4b. The two ts mutants display normal patterns of gene expression, DNA replication, telomere resolution, and protein processing during infection. Morphogene...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2004.08.038
更新日期:2004-12-05 00:00:00
abstract::A minor core protein, VP4, of bluetongue virus serotype 10 (BTV-10) has been synthesized in insect cells infected with a genetically manipulated recombinant baculovirus. When insect cells were coinfected by this recombinant virus and a recombinant baculovirus expressing the two major core proteins (VP3 and VP7) of the...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(92)90600-t
更新日期:1992-08-01 00:00:00
abstract::DNA obtained from New Zealand white rabbit oral papillomas was analyzed for the presence of papillomavirus DNA. The viral genome was cloned as three separate subclones, which were each mapped and oriented with respect to one another. Comparisons with other papillomavirus DNAs by Southern blot hybridization under vario...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(88)90411-4
更新日期:1988-01-01 00:00:00
abstract::The influenza RNA polymerase is known to catalyse three distinct copying activities: (i) transcription of minus-sense virion RNA (vRNA) into mRNA, (ii) transcription of vRNA into full-length complementary RNA (cRNA), and (iii) transcription of cRNA to vRNA. Ever since the discovery of the conserved 13 and 12 long sequ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(92)90079-5
更新日期:1992-01-01 00:00:00
abstract::Alternative splicing of pre-mRNAs plays a critical role in maximizing the coding capacity of the small parvovirus genome. The small-intron region of minute virus of mice (MVM) pre-mRNAs undergoes an unusual pattern of overlapping alternative splicing, using two donors, D1 and D2, and two acceptors, A1 and A2, within a...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1999.9696
更新日期:1999-05-25 00:00:00
abstract::The sequences of 189 residues from the 3' terminus of three RNAs of one strain and two RNAs of another strain of tomato aspermy virus have been determined; there was almost complete sequence homology between the RNAs. A base-paired transfer RNA-like structure is proposed for tomato aspermy virus RNAs which is similar ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(81)90639-5
更新日期:1981-07-15 00:00:00
abstract::Multiple nucleoside resistance involves specific mutational patterns of the HIV-1 pol gene that are independent of the classic mutations conferring resistance to individual dideoxynucleosides. These include a cluster of five mutations in the reverse-transcriptase (RT) coding region (A62V, V75I, F77L, F116Y, and Q151M)...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.2000.0261
更新日期:2000-05-10 00:00:00
abstract::Porcine circovirus type 2 (PCV2) is an economically important cause of post-weaning multisystemic wasting syndrome (PMWS) in weanling piglets. Current commercial vaccines against PCV2 are highly effective. Yet, a recurring emergence of new genotypes in vaccinated herds necessitates a better understanding of protective...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2019.11.008
更新日期:2020-01-15 00:00:00
abstract::Phase I human clinical studies involving therapeutics for emerging and biodefense pathogens with low incidence, such as the severe acute respiratory syndrome coronavirus (SARS-CoV), requires at a minimum preclinical evaluation of efficacy in two well-characterized and robust animal models. Thus, a ferret SARS-CoV mode...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2007.12.032
更新日期:2008-04-25 00:00:00