Abstract：
:The presentation of peptides to T cells by MHC class II molecules is of critical importance in specific recognition by the immune system. Expression of class II molecules is exquisitely controlled at the transcriptional level. A large set of proteins interact with the promoters of class II genes. The most important of these is CIITA, a master controller that orchestrates expression but does not bind directly to the promoter. The transcriptosome complex formed at class II promoters is a model for induction of gene expression.
journal_name
Celljournal_title
Cellauthors
Ting JP,Trowsdale Jdoi
10.1016/s0092-8674(02)00696-7subject
Has Abstractpub_date
2002-04-01 00:00:00pages
S21-33eissn
0092-8674issn
1097-4172pii
S0092867402006967journal_volume
109 Supplpub_type
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