Mapping the SRY gene in Microtus cabrerae: a vole species with multiple SRY copies in males and females.

Abstract:

:The SRY gene is a single-copy, male-specific gene, located on the Y chromosome in most mammals. However, recently we have described the presence of multiple polymorphic copies of this gene in both males and females of the vole species Microtus cabrerae. Here, we present the chromosomal localization of SRY gene copies in this species by fluorescent in situ hybridization (FISH). This technique localized these gene copies in the short arm, and hence in the euchromatic region, of the Y chromosome. Furthermore, several copies of the SRY gene are located on the X chromosome. These copies are spread along the entire heterochromatic region of the X chromosome, occupying the whole short arm, the centromeric region, and the pericentromeric region of the long arm.

journal_name

Genome

journal_title

Genome

authors

Fernández R,Barragán MJ,Bullejos M,Marchal JA,Martínez S,Díaz de la Guardia R,Sánchez A

doi

10.1139/g02-007

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

600-3

issue

3

eissn

0831-2796

issn

1480-3321

journal_volume

45

pub_type

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