Brightness discrimination learning under conditions of cue enhancement by rats with lesions in the amygdala or hippocampus.

abstract：:Changes in synaptic efficacy, including long-term potentiation (LTP) and long-term depression (LTD), provide mechanisms for experience-induced plasticity of cortical and subcortical circuits. LTP is readily induced under drastically different experimental conditions (e.g., in vitro and in vivo). However, few studies h...

journal_title：Brain research

authors： Hager AM,Dringenberg HC

更新日期：2010-03-08 00:00:00

abstract：:Combined amylin+leptin (AMN+LEP) can reduce diet induced obesity and is very effective in combating LEP resistance. The purpose of this study was to evaluate the effect of AMN+LEP on central histaminergic signaling in lean and obese rats. Male rats were administered LEP (300 μg/kg/d), AMN (100 μg/kg/d), AMN+LEP or veh...

journal_title：Brain research

authors： Seth R,Terry DE,Parrish B,Bhatt R,Overton JM

更新日期：2012-03-09 00:00:00

abstract：:The effects of forced swimming for 30 min on extracellular 5-hydroxytryptamine (5-HT) levels were examined in five brain regions in rats using in vivo microdialysis. A single dialysis probe was implanted under surgical anesthesia into either the striatum, ventral hippocampus, frontal cortex, amygdala, or lateral septu...

journal_title：Brain research

authors： Kirby LG,Allen AR,Lucki I

更新日期：1995-06-05 00:00:00

abstract：:In order to better understand the neuroleptic-like effects of neurotensin in vivo, the effects of neurotensin in vitro on dopamine D2 and D1 agonist and antagonist binding sites were characterized in membranes from the neostriatum and the subcortical limbic area. Neurotensin increased the KD but not the Bmax value of ...

journal_title：Brain research

authors： von Euler G

更新日期：1991-10-04 00:00:00

abstract：:The enzymatic and regulatory properties of Ca2+/calmodulin-dependent protein kinase in the postsynaptic density (mPSDp CaM kinase) of the rat forebrain was compared with those of soluble Ca2+/calmodulin-dependent protein kinase II (CaM kinase II). mPSDp CaM kinase was different from soluble CaM kinase II in terms of s...

journal_title：Brain research

authors： Ochiishi T,Sugiura H,Yamauchi T

更新日期：1993-04-30 00:00:00

abstract：:Pentobarbital-anesthetized rats received electrical hindpaw stimulation every 10 s to elicit a maximal hindlimb withdrawal reflex. The integrated EMG response in the ipsilateral tibialis anterior was sampled by a computer which also controlled the timing of electrical stimuli applied to the brain. A suppression of the...

journal_title：Brain research

authors： Duysens J,Dom R,Gybels J

更新日期：1989-10-09 00:00:00

abstract：:The therapeutic effects of dextrorphan and ketamine, two non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists, on neuropathic pain-related behaviors were examined in rats with peripheral mononeuropathy induced by loose ligation of the common sciatic nerve (chronic constrictive injury, CCI). Four daily intr...

journal_title：Brain research

authors： Mao J,Price DD,Hayes RL,Lu J,Mayer DJ,Frenk H

更新日期：1993-03-05 00:00:00

abstract：:Monoamine oxidase A and B (MAO A and B; EC 1.4.3.4) are integral proteins of the outer mitochondrial membrane that degrade monoamines including the neurotransmitters norepinephrine, dopamine, and serotonin. In this study, monoclonal antibodies that recognize rat or monkey MAO A were used in immunocytochemical studies ...

journal_title：Brain research

authors： Westlund KN,Krakower TJ,Kwan SW,Abell CW

更新日期：1993-05-28 00:00:00

abstract：:The development of the dorsal root potential (DRP) and the responsiveness of primary afferent fibers to gamma-aminobutyric acid (GABA) were investigated in the isolated spinal cord of rat fetuses. At embryonic day 15.5, stimulation of the lumbar dorsal root was first effective in eliciting the DRP, which was not inhib...

journal_title：Brain research

authors： Seno N,Saito K

更新日期：1985-01-01 00:00:00

abstract：:Light microscopic double labeling immunocytochemistry for vasoactive intestinal peptide (VIP) and gonadotrophin-releasing hormone (GnRH) was carried out on the hypothalami of male and female rats. It was found that the number of VIP boutons that terminate on GnRH neurons and the percentage of GnRH neurons contacted by...

journal_title：Brain research

authors： Horvath TL,Cela V,van der Beek EM

更新日期：1998-06-08 00:00:00

abstract：:We evaluated the effects of glycine exposure upon CA1-evoked response in the rat hippocampal slice. Exposure to 10 mM glycine for 16 min produced rapid neuronal firing and increased orthodromic population spike (PS), followed by loss of CA1 neural transmission. Upon recovery, CA1 orthodromic and antidromic PS regained...

journal_title：Brain research

authors： Wallis RA,Panizzon KL,Nolan JP

更新日期：1994-11-21 00:00:00

abstract：:Basic fibroblast growth factor (b-FGF) and alpha melanocyte stimulating hormone (alpha-MSH) were tested for their ability to promote axonal elongation on E14 fetal rat spinal cord cell culture, and to support cell survival. A similar development of neurite was observed in alpha-MSH treated cultures or in control cultu...

journal_title：Brain research

authors： Peulve P,Laquerriere A,Hemet J,Tadie M

更新日期：1994-08-22 00:00:00

abstract：:The nictitating membrane response to periocular electrostimulation was investigated in anesthetized and paralyzed rabbits. Recordings from the abducens nerve, which carries the fibers innervating retractor bulbi muscles that are primarily involved in this reflex, showed two distinct volleys to effective stimulation: a...

journal_title：Brain research

authors： Berthier NE,Moore JW

更新日期：1983-01-10 00:00:00

abstract：:The rostral brainstem and thalamus of awake cats were studied for depth correlates of a surface-recorded midlatency auditory evoked potential, wave "A', with a latency range of 17-25 ms. In response to clicks or pure tones, midlatency potentials were recorded from the level of the cuneiform nucleus (14-15 ms latencies...

journal_title：Brain research

authors： Hinman CL,Buchwald JS

更新日期：1983-03-28 00:00:00

abstract：:High cell density, with attendant aggregation, selectively increases expression of substance P (SP) and choline acetyltransferase (ChAT) in virtually pure neonatal sympathetic neuronal cultures. To investigate the specific role of cell contact in selective transmitter expression, SP content and ChAT activity were exam...

journal_title：Brain research

authors： Adler JE,Black IB

更新日期：1986-12-01 00:00:00

abstract：:Basal sleep amounts in adrenalectomized rats (AdX), as compared to intact animals, exhibit a significant increase in slow-wave sleep (SWS), a tendency towards an increase in paradoxical sleep (PS), and circadian rhythms (SWS and PS) flattened in amplitude. An immobilization stress (IS) of 1 h, imposed on AdX rats at t...

journal_title：Brain research

authors： Bonnet C,Marinesco S,Debilly G,Kovalzon V,Cespuglio R

更新日期：2000-01-24 00:00:00

abstract：:There is emerging evidence that increased acetylcholine levels in brain reduce anxiety. More specifically there is evidence that some of these anxiolytic effects of acetylcholine are modulated by the hippocampus. In the present study we examined the roles of the cholinergic systems in the dorsal and ventral hippocampu...

journal_title：Brain research

authors： Degroot A,Treit D

更新日期：2002-09-13 00:00:00

abstract：:We have used magnetic resonance imaging (MRI) of the living rat brain to longitudinally analyze the ontogenesis of an ibotenic acid lesion targeted at the piriform cortex. The MRI data were systematically compared with data obtained from a battery of histopathological techniques, including Nissl stain, hematoxylin sta...

journal_title：Brain research

authors： Ben-Horin N,Hazvi S,Bendel P,Schul R

更新日期：1996-04-29 00:00:00

abstract：:Snake venom kappa-neurotoxins are selective antagonists of nicotinic acetylcholine responses in avian, murine and bovine neurons, and have been used as probes for functionally defined vertebrate neuronal nicotinic receptors. The actions of kappa-bungarotoxin, a kappa-neurotoxin, have now been examined at a central inv...

journal_title：Brain research

authors： Pinnock RD,Lummis SC,Chiappinelli VA,Sattelle DB

更新日期：1988-08-16 00:00:00

abstract：:4-Aminopyridine (4-AP), bicuculline and GABA were applied locally to dorsal horn cells in the lumbar spinal cord in Nembutal-anaesthetized cats and in spinal cats. 4-AP expanded the cutaneous receptive field of 29 of 33 cells tested. Bicuculline and GABA had little or no effect on receptive field size. ...

journal_title：Brain research

authors： Saadé N,Jabbur SJ,Wall PD

更新日期：1985-10-07 00:00:00

abstract：:Protein phosphatases (PPs) regulate many substrates implicated in learning and memory. Conditioned taste aversion (CTA) learning, in which animals associate a novel taste paired with a toxin and subsequently avoid the taste, is dependent on several serine/threonine phosphatase substrates and the PP1-binding protein sp...

journal_title：Brain research

authors： Oberbeck DL,McCormack S,Houpt TA

更新日期：2010-08-12 00:00:00

abstract：:In the companion study (Dev. Brain Res., 34 (1987) 223-233), we showed that a monocular injection of antibodies against ox large retinal ganglion cells produces a 53% (low concentration) to 82% (high concentration) loss of Y-cells in lateral geniculate nucleus (LGN) layers A and A1 that receive inputs from the antibod...

journal_title：Brain research

authors： McCall MA,Spear PD,Crabtree JW,Kornguth SE

更新日期：1987-08-01 00:00:00

abstract：:Basic FGF has recently been shown to produce systemic and cerebral vasodilation. To test the hypothesis that bFGF increases regional cortical blood flow (rCBF), rCBF and brain pHi were measured while bFGF or vehicle was superperfused onto the cortex of rabbits. The results of this study demonstrate that topical applic...

journal_title：Brain research

authors： Regli L,Anderson RE,Meyer FB

更新日期：1994-11-28 00:00:00

abstract：:The distribution of carnosine-like immunoreactivity in photoreceptors of the frog retina was studied by post-embedding electron microscope immunocytochemistry. Different fixation and embedding procedures were applied and the best results were achieved on sections from tissue embedded in the hydrophilic resin LR White....

journal_title：Brain research

authors： Pognetto MS,Cantino D,Fasolo A

更新日期：1992-04-24 00:00:00

abstract：:In the quinolinic acid (QA)-rat model of Huntington's disease (HD), 15 days after QA injection, striatal glutamate, measured by in vivo microdialysis, was unchanged while a significant decrease in adenosine occurred. The decrease in adenosine may depend on QA-induced striatal cell loss. Probe perfusion of the adenosin...

journal_title：Brain research

authors： Gianfriddo M,Corsi C,Melani A,Pèzzola A,Reggio R,Popoli P,Pedata F

更新日期：2003-07-25 00:00:00

abstract：:Soluble amyloid beta protein (A beta)1-40 and highly amyloidogenic A beta 1-42/43 were immunocytochemically labeled in lysosomes of acinar cells and macrophages in the pancreas of transgenic mice systemically expressing a C-terminal fragment of the A beta precursor. A beta 1-42/43 and long A beta species extending the...

journal_title：Brain research

authors： Kawarabayashi T,Igeta Y,Sato M,Sasaki A,Matsubara E,Kanai M,Tomidokoro Y,Ishiguro K,Okamoto K,Hirai S,Shoji M

更新日期：1997-08-15 00:00:00

abstract：:In rats raised from birth under a regular dark-light cycle, retinal dopamine (DA) levels were low at 12 days, increased progressively and steeply at 16, 20, 30 and 60 days and peaked at about 75 days postnatally. Dark-rearing from birth suppressed the magnitude of the normal developmental pattern of DA concentrations ...

journal_title：Brain research

authors： Melamed E,Frucht Y,Vidauri J,Uzzan A,Rosenthal J

更新日期：1986-05-01 00:00:00

abstract：:Neuropeptides, including substance P (SP), calcitonin gene-related peptide (CGRP) and somatostatin (SS) in dorsal root ganglia (DRG) may play a role in neurogenic inflammation and pain transmission. Adrenal corticosteroids regulate neuropeptide synthesis in some areas of the CNS and may modulate neurogenic inflammatio...

journal_title：Brain research

authors： Smith GD,Seckl JR,Sheward WJ,Bennie JG,Carroll SM,Dick H,Harmar AJ

更新日期：1991-11-08 00:00:00

abstract：:Trisomy 21 (Down syndrome) results in abnormalities in electrical membrane properties of cultured human fetal dorsal root ganglion (DRG) neurons. Action potentials have faster rates of depolarization and repolarization, with decreased spike duration, compared to diploid neurons. In order to analyze the faster depolari...

journal_title：Brain research

authors： Caviedes P,Ault B,Rapoport SI

更新日期：1990-03-05 00:00:00

abstract：:The distribution of cells expressing mu-receptor mRNA and mu-receptor binding sites were compared in brain and spinal cord tissue sections using a combination of in situ hybridization and receptor autoradiographic techniques. mu-Receptor mRNA was visualized with a 35S-labeled cRNA probe directed to transmembrane III-V...

journal_title：Brain research

authors： Mansour A,Fox CA,Thompson RC,Akil H,Watson SJ

更新日期：1994-04-18 00:00:00