Doppler echocardiographic detection of left ventricular diastolic dysfunction in patients with pulmonary sarcoidosis.

Abstract:

STUDY OBJECTIVE:To determine the prevalence of left ventricular diastolic dysfunction in patients with biopsy specimen-proved pulmonary sarcoidosis without clinical evidence of cardiac disease. DESIGN:A cross-sectional study. SETTING:A large tertiary care university teaching hospital. PATIENTS AND CONTROL SUBJECTS:Fifty consecutive subjects had biopsy specimen-proved pulmonary sarcoidosis without suspected cardiac involvement. Those with other conditions known to affect diastolic function were excluded. The control group comprised 30 healthy hospital workers. INTERVENTIONS:Clinical examination, 12-lead ECG, and combined echocardiographic/phonocardiographic examination. MEASUREMENTS:Indexes of left ventricular diastolic function, including isovolumic relaxation time, peak velocity of early (E) and late (A) ventricular filling, deceleration rate of early diastolic flow, and the sum of the time velocity integrals of E and A were obtained in each patient and control subject. Systolic function was determined using a modification of Simpson's rule. RESULTS:Diastolic dysfunction was present in 7 (14%) patients, 6 of whom had normal systolic function and normal two-dimensional echocardiographic examination. Those with diastolic dysfunction had a longer duration of illness (15 +/- 7 vs 6 +/- 5 years; p = 0.0004), were significantly older (52 +/- 11 vs 38 +/- 9 years; p = 0.0009), and had higher systolic BP (130 +/- 13 vs 117 +/- 12 mm Hg; p = 0.01) than the sarcoid patients with normal diastolic function. CONCLUSIONS:These results demonstrate a significant prevalence of left ventricular diastolic dysfunction in patients with pulmonary sarcoidosis. The cause of this abnormality may be a subclinical sarcoid cardiomyopathy.

journal_name

Chest

journal_title

Chest

authors

Fahy GJ,Marwick T,McCreery CJ,Quigley PJ,Maurer BJ

doi

10.1378/chest.109.1.62

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

62-6

issue

1

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)45588-6

journal_volume

109

pub_type

杂志文章

相关文献

CHEST文献大全
  • Hypercalcemia due to talc granulomatosis.

    abstract::Pulmonary disease due to talc, a group of hydrous magnesium silicates, is almost exclusively encountered after occupational exposure. One form of this rare disorder is talc granulomatosis. In varying degrees, hypercalcemia is typical of granulomatous disease but has not yet been reported in talcosis. We report the cas...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.117.4.1195

    authors: Woywodt A,Schneider W,Goebel U,Luft FC

    更新日期:2000-04-01 00:00:00

  • The prevalence of exercise-induced bronchospasm among US Army recruits and its effects on physical performance.

    abstract:STUDY OBJECTIVES:To measure the prevalence of exercise-induced bronchospasm (EIB) and to determine its effect on the physical performance response to training in otherwise healthy young adults. DESIGN:Observational, retrospective study. SETTING:Fort Jackson, SC, May to July 1998. PARTICIPANTS:One hundred thirty-seve...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.119.6.1676

    authors: Sonna LA,Angel KC,Sharp MA,Knapik JJ,Patton JF,Lilly CM

    更新日期:2001-06-01 00:00:00

  • Pulmonary hypertension secondary to thrombocytosis in a patient with myeloid metaplasia.

    abstract::A 72-year-old physician with myeloid metaplasia developed marked thrombocytosis, pulmonary hypertension, and right heart failure following splenectomy. No cause for the pulmonary hypertension could be found. The pulmonary hypertension and right heart failure returned to normal when hydroxyurea therapy corrected the th...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.2.642

    authors: Marvin KS,Spellberg RD

    更新日期:1993-02-01 00:00:00

  • DVT Management and Outcome Trends, 2001 to 2014.

    abstract:BACKGROUND:A comprehensive evaluation of temporal trends in the treatment of patients who have DVT may assist with identification of modifiable factors that contribute to short-term outcomes. METHODS:We assessed temporal trends in length of hospital stay and use of pharmacological and interventional therapies among 26...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2016.03.046

    authors: Morillo R,Jiménez D,Aibar MÁ,Mastroiacovo D,Wells PS,Sampériz Á,Saraiva de Sousa M,Muriel A,Yusen RD,Monreal M,RIETE investigators.

    更新日期:2016-08-01 00:00:00

  • Diaphragmatic excursion after pleural sclerosis.

    abstract::Chemical sclerosis of the pleural space is used to prevent recurrence of spontaneous pneumothorax. To test whether sclerosis restricts diaphragmatic excursion, we measured diaphragmatic excursion by ultrasonography in subjects with unilateral pleural sclerosis and compared it with diaphragmatic excursions in normal su...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.95.2.374

    authors: Loring SH,Kurachek SC,Wohl ME

    更新日期:1989-02-01 00:00:00

  • Whole-lung lavage in alveolar proteinosis by a modified lavage technique.

    abstract::Whole-lung lavage is the only efficient treatment in pulmonary alveolar proteinosis. A 36-year-old woman with severe pulmonary alveolar proteinosis confirmed by video-assisted thoracoscopic lung biopsies underwent repetitive whole-lung lavages without improvement. A modified technique consisting of manual ventilation ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.113.6.1718

    authors: Bingisser R,Kaplan V,Zollinger A,Russi EW

    更新日期:1998-06-01 00:00:00

  • Pleural Myiasis Associated With Pleural Angiosarcoma.

    abstract::Myiasis refers to a parasitic infestation of vertebrate mammals by dipterous larvae (maggots) of higher flies. Infections in humans typically occur in tropical and subtropical regions, regions with limited medical access, and areas with poor hygiene and living conditions. Infestations in humans have been described in ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2015.12.022

    authors: Patel MB,Munzer K,Dougherty M,Williams P,Loiselle A

    更新日期:2016-06-01 00:00:00

  • Homogeneity of bronchopulmonary distribution of 99mTc aerosol in normal subjects and in cystic fibrosis patients.

    abstract::We characterized the bronchopulmonary distribution of a 0.9 percent saline aerosol (1.12 microM) labelled with 99mTc sulfur colloid in nine normal subjects and five patients with CF. Homogeneity of distribution was quantified using indices derived from computerized analysis of Anger camera pulmonary images including s...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.95.4.822

    authors: Laube BL,Links JM,LaFrance ND,Wagner HN Jr,Rosenstein BJ

    更新日期:1989-04-01 00:00:00

  • Do native and polymeric alpha1-antitrypsin activate human neutrophils in vitro?

    abstract:BACKGROUND:alpha(1)-Antitrypsin (AAT)-Z deficiency is a risk factor for the development of COPD. Compared to wild-type M, AAT-Z has an increased tendency to polymerize, rendering it inactive as a serine proteinase inhibitor. It has been demonstrated that wild-type M- and Z-deficiency AAT polymers are chemotactic for hu...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.129.6.1683

    authors: Persson C,Subramaniyam D,Stevens T,Janciauskiene S

    更新日期:2006-06-01 00:00:00

  • Pulmonary vein obstruction following single lung transplantation.

    abstract::Angiographic documentation after single lung transplant showed pulmonary venous obstruction due to compression by the omental pedicle. Retransplantation is described, and this complication is examined. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.2.645

    authors: Malden ES,Kaiser LR,Gutierrez FR

    更新日期:1992-08-01 00:00:00

  • Left ventricular function in myocardial infarction. Predictive value during negative low-level exercise three weeks postinfarction.

    abstract::To evaluate whether the response of left ventricular pump function during low-level exercise in the early postinfarction period can anticipate its change during the first year after acute myocardial infarction (MI), global and regional ejection fractions (EF) were investigated using radionuclide angiography in 52 cons...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.2.335

    authors: Iwasaka T,Sugiura T,Nakamura S,Okubo N,Inada M

    更新日期:1992-08-01 00:00:00

  • Long-term effects of nitrendipine on hemodynamics and oxygen transport in patients with cor pulmonale.

    abstract::Recent studies have suggested that vasodilators may acutely improve pulmonary hemodynamics in patients with chronic obstructive pulmonary disease and cor pulmonale, but the effects of long-term therapy have not been assessed. We evaluated the hemodynamic and gas exchange effects of nitrendipine, a calcium channel bloc...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.89.1.141

    authors: Rubin LJ,Moser K

    更新日期:1986-01-01 00:00:00

  • Outcome of treated advanced non-small cell lung cancer with and without central airway obstruction.

    abstract:OBJECTIVE:In patients with advanced non-small cell lung cancer (NSCLC) treated with chemotherapy, we compared survival in patients with treated central airway obstruction to those who did not have central airway obstruction. METHODS:One hundred forty-four patients with advanced and inoperable NSCLC were included. Thes...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.6.1803

    authors: Chhajed PN,Baty F,Pless M,Somandin S,Tamm M,Brutsche MH

    更新日期:2006-12-01 00:00:00

  • Gastric tonometry in patients with sepsis. Effects of dobutamine infusions and packed red blood cell transfusions.

    abstract::We wanted to determine the efficacy of dobutamine infusions and Prbc transfusions on splanchnic tissue oxygen utilization by measuring gastric pHi. Physiologic parameters and pHi measurements via the use of a gastric tonometer were obtained in 21 septic patients before and after the administration of a dobutamine infu...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.1.184

    authors: Silverman HJ,Tuma P

    更新日期:1992-07-01 00:00:00

  • Comparing two heat and moisture exchangers with one vaporizing humidifier in patients with minute ventilation greater than 10 L/min.

    abstract:STUDY OBJECTIVE:To evaluate in patients submitted to minute ventilation > 10 L/min the ability to preserve patients' heat and humidity of two heat and moisture exchangers (HMEs) and one vaporizing humidifier (VH). DESIGN:Prospective, randomized, comparative, non-blinded study. SETTING:Intensive care unit of a univers...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.107.5.1411

    authors: Martin C,Thomachot L,Quinio B,Viviand X,Albanese J

    更新日期:1995-05-01 00:00:00

  • Factitious methemoglobinemia caused by hyperlipemia.

    abstract::Hyperlipemia in an acyanotic patient with diabetic ketoacidosis, alcoholism, and pancreatitis produced a falsely elevated concentration of methemoglobin (19 percent) and a lower-than-expected oxygen saturation measured with an automated spectrophotometer (IL-282 CO-Oximeter). In addition, there was a "normal" hemoglob...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.86.1.84

    authors: Spurzem JR,Bonekat HW,Shigeoka JW

    更新日期:1984-07-01 00:00:00

  • Telescoping plugged catheter. An unusual way of diagnosing Pasteurella multocida pneumonia.

    abstract::We report a case of Pasteurella multocida pneumonia and its unusual clinical presentation. We also discuss the rarity of its diagnosis by TPC specimens and the delay in both an adequate diagnosis and treatment. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.99.6.1517

    authors: Ruiz-Santana S,Antunez IA,Armas M,Rodriguez de Castro F,Manzano JL

    更新日期:1991-06-01 00:00:00

  • Enoximone vs nicardipine during the early postoperative course of patients undergoing cardiac surgery. A prospective study of two therapeutic strategies.

    abstract::The hemodynamic effects of enoximone and nicardipine were compared during the early postcardiac surgery period in 40 patients with systemic hypertension and moderate cardiac dysfunction. Patients were prospectively randomized into two groups. Mean right atrial pressure was maintained above 7 mm Hg. The drug infusion r...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.106.1.52

    authors: Squara P,Denjean D,Godard P,Brunet F,Brusset A,Dubois C

    更新日期:1994-07-01 00:00:00

  • Sleep apnea syndrome and cerebral hemodynamics.

    abstract::The dynamics of cerebral blood flow velocity (CBFV) during sleep were investigated in the right middle cerebral artery of 10 patients with sleep apnea syndrome (SAS) (mean age, 37 years) and 10 healthy control subjects (mean age, 32 years) throughout the entire sleep period. A computer-assisted pulsed (2 MHz) transcra...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.3.670

    authors: Hajak G,Klingelhöfer J,Schulz-Varszegi M,Sander D,Rüther E

    更新日期:1996-09-01 00:00:00

  • Differences in the response to methacholine between the tidal breathing and dosimeter methods: influence of the dose of bronchoconstrictor agent delivered to the mouth.

    abstract:BACKGROUND:It has been postulated that differences in provocative concentration of methacholine causing a 20% fall in FEV1 (PC20) values between the dosimeter method and tidal breathing method might be due to differences in the dose of agonist delivered to the mouth. The aim of the present study was to determine the in...

    journal_title:Chest

    pub_type: 杂志文章,随机对照试验

    doi:10.1378/chest.08-0093

    authors: Prieto L,Lopez V,Llusar R,Rojas R,Marin J

    更新日期:2008-10-01 00:00:00

  • Bronchial leukocyte proteinase inhibitor levels in bronchial washings in asthma patients.

    abstract::To evaluate whether epithelial damage of airways in asthma could be related to diminished levels of the low molecular weight bronchial leukocyte proteinase inhibitor (BLPI) in airways, we determined BLPI in bronchial washings of 13 asthma patients and 13 healthy subjects, using a sensitive enzyme-linked immunoassay. T...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.5.1008

    authors: Ochnio JJ,Abboud RT,Lam S,Johal SS,Smith CE,Johnson DA

    更新日期:1988-05-01 00:00:00

  • Evaluation of respiratory inductive plethysmography in the measurement of breathing pattern and PEEP-induced changes in lung volume.

    abstract:STUDY OBJECTIVE:To assess the accuracy of the respiratory inductive plethysmography in the measurement of PEEP-induced changes in end-expiratory lung volume during mechanical ventilation and its accuracy and stability in the measurement of ventilation during controlled mechanical ventilation and spontaneous breathing. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.1.234

    authors: Valta P,Takala J,Foster R,Weissman C,Kinney JM

    更新日期:1992-07-01 00:00:00

  • Interpretation of cough provoked by airway challenges.

    abstract:STUDY OBJECTIVE:To analyze the cough response to three airway challenges in order to clarify whether the recording of the provoked coughs would be beneficial in the management of asthma. DESIGN:A prospective study. SETTING:University hospital. PARTICIPANTS:Fifteen healthy subjects, 16 steroid-naïve subjects with ast...

    journal_title:Chest

    pub_type: 杂志文章,随机对照试验

    doi:10.1378/chest.128.5.3329

    authors: Koskela HO,Kontra KM,Purokivi MK,Randell JT

    更新日期:2005-11-01 00:00:00

  • Diagnostic utility of ventilation/perfusion lung scans in acute pulmonary embolism is not diminished by pre-existing cardiac or pulmonary disease.

    abstract::The purpose of this study was to assess the impact of prior cardiac or pulmonary disease upon the utility of ventilation/perfusion (V/Q) scans in the diagnosis of acute pulmonary embolism (PE). Ventilation/perfusion scans were evaluated among 365 patients with no prior cardiac or pulmonary disease and compared to V/Q ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.3.604

    authors: Stein PD,Coleman RE,Gottschalk A,Saltzman HA,Terrin ML,Weg JG

    更新日期:1991-09-01 00:00:00

  • Esophagectomy after induction chemoradiation.

    abstract::The definition of a standard therapy for resectable esophageal cancer remains a clinical controversy. In the past decade, a variety of strategies have been developed in an attempt to improve local control and decrease the all too common problem of distant metastases. Preoperative treatment with radiotherapy or chemoth...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.116.suppl_3.466s

    authors: DeCamp MM Jr,Swanson SJ,Jaklitsch MT

    更新日期:1999-12-01 00:00:00

  • Acute lung disease in the immunocompromised host. Diagnostic accuracy of the chest radiograph.

    abstract:PURPOSE:To assess the diagnostic accuracy of the chest radiograph in the evaluation of acute pulmonary complications in immunocompromised patients. METHODS:The study included the chest radiographs in 149 consecutive acute pulmonary complications seen in immunocompromised patients in whom a definitive diagnosis was mad...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.5.1283

    authors: Logan PM,Primack SL,Staples C,Miller RR,Müller NL

    更新日期:1995-11-01 00:00:00

  • Gaps in COPD Guidelines of Low- and Middle-Income Countries: A Systematic Scoping Review.

    abstract:BACKGROUND:Guidelines are critical for facilitating cost-effective COPD care. Development and implementation in low-and middle-income countries (LMICs) is challenging. To guide future strategy, an overview of current global COPD guidelines is required. RESEARCH QUESTION:We systematically reviewed national COPD guideli...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.09.260

    authors: Tabyshova A,Hurst JR,Soriano JB,Checkley W,Wan-Chun Huang E,Trofor AC,Flores-Flores O,Alupo P,Gianella G,Ferdous T,Meharg D,Alison J,Correia de Sousa J,Postma MJ,Chavannes NH,van Boven JFM

    更新日期:2020-10-08 00:00:00

  • Löffler's syndrome secondary to crack cocaine.

    abstract::Eosinophilic pulmonary infiltration is an uncommon presentation from cocaine abuse. We present a patient with migratory pulmonary infiltrates and eosinophilia consistent with Löffler's syndrome. Our review uncovered two other similar patients. The importance of early recognition is stressed in our report. Either absti...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.105.5.1599

    authors: Nadeem S,Nasir N,Israel RH

    更新日期:1994-05-01 00:00:00

  • Use of transesophageal echocardiography for diagnosis of traumatic aortic injury.

    abstract::This prospective study was conducted to describe the signs on transesophageal echocardiography (TEE) associated with traumatic aortic injury (TAI). Twenty-eight patients with TAI underwent TEE, and they were compared with a control group of 30 thoracic trauma patients without aortic injury. The TEE signs were classifi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.112.1.71

    authors: Goarin JP,Catoire P,Jacquens Y,Saada M,Riou B,Bonnet F,Coriat P

    更新日期:1997-07-01 00:00:00

  • Neurosarcoidosis: a personal perspective based on the study of 37 patients.

    abstract::Clinically apparent involvement of the nervous system occurs in a relatively small number of patients with sarcoidosis. The diagnosis of neurosarcoidosis is often difficult and particularly so in patients who lack either pulmonary or systemic manifestations of sarcoidosis. Furthermore, clinical features of neurosarcoi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.112.1.220

    authors: Sharma OP

    更新日期:1997-07-01 00:00:00