Abstract:
STUDY OBJECTIVES:To measure the prevalence of exercise-induced bronchospasm (EIB) and to determine its effect on the physical performance response to training in otherwise healthy young adults. DESIGN:Observational, retrospective study. SETTING:Fort Jackson, SC, May to July 1998. PARTICIPANTS:One hundred thirty-seven ethnically diverse US Army recruits undergoing an 8-week Army basic training course. MEASUREMENTS AND RESULTS:Subjects underwent exercise challenge testing at the end of basic training to evaluate for EIB (defined as a decrease in FEV(1) of > or = 15%, 1 or 10 min after running to peak oxygen uptake on a treadmill). Those subjects who were unable to run to peak oxygen uptake, or who were unable to perform two baseline FEV(1) maneuvers the results of which were within 5% of each other, were excluded from analysis. We measured peak oxygen uptake on a treadmill and the scores achieved on the components of the US Army physical fitness test (APFT). Of 137 subjects, 121 (58 men and 63 women) met our inclusion criteria. Eight subjects (7%) had EIB. Subjects who experienced EIB and unaffected control subjects both showed statistically significant gains in performance on the APFT events during basic training. At the end of basic training, peak oxygen uptake levels and APFT event scores were not significantly different between subjects with EIB and unaffected control subjects. CONCLUSIONS:Seven percent of the US Army recruits who were tested had EIB, but this did not hinder their physical performance gains during basic training. EIB per se should not be an absolute reason to exclude individuals from employment in jobs with heavy physical demands.
journal_name
Chestjournal_title
Chestauthors
Sonna LA,Angel KC,Sharp MA,Knapik JJ,Patton JF,Lilly CMdoi
10.1378/chest.119.6.1676subject
Has Abstractpub_date
2001-06-01 00:00:00pages
1676-84issue
6eissn
0012-3692issn
1931-3543pii
S0012-3692(15)52312-Xjournal_volume
119pub_type
杂志文章相关文献
CHEST文献大全abstract::Immunohistochemistry has come to occupy a key position among the armamentarium of tools pathologists apply to the evaluation of lung and pleural neoplasms. This technique uses antibodies that bind to specific antigens, usually proteins, enabling microscopic detection of the antigens. Over the last several decades, an ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.11-3327
更新日期:2012-11-01 00:00:00
abstract::A mechanical model was employed to examine phase and amplitude relationships between simulated pleural and mouth pressures during panting at different frequencies with and without lower airway obstruction and with rigid or flaccid extrathoracic airways. Results confirm the hypothesis that, in the presence of lower air...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.86.4.589
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare the safety, use, and cost profiles of open thoracotomy vs video-assisted thoracoscopic surgery (VATS) for wedge resection in lung cancer performed by thoracic surgeons in the United States. METHODS:The Premier database, which contains complete patient billing, hospi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-3013
更新日期:2012-02-01 00:00:00
abstract::A 55-year-old woman had bilateral hilar lymphadenopathy and retinouveitis. Microscopic examination of a biopsy specimen from a mediastinal lymph node revealed noncaseating epithelioid cell granulomas. Since granulomatous diseases of infectious origin and sarcoid reaction were reasonably excluded, she was diagnosed as ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.95.1.228
更新日期:1989-01-01 00:00:00
abstract::Solitary extramedullary plasmacytomas are uncommon neoplasms. They occur most frequently in the upper aerodigestive tract and account for 4% of the nonepithelial tumors in this site. The evolution of a plasmacytoma is unsteady and symptoms at presentation have included dystonia, dysphagia, oral pain, cough, and dyspne...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.109.6.1657
更新日期:1996-06-01 00:00:00
abstract::We report a case of pancreatitis, which occurred while the patient was on a propofol drip and then recurred after resolution following an inadvertent rechallenge with propofol. The initial episode was associated with hypertriglyceridemia, whereas the latter was not. The association between propofol and pancreatitis is...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.115.4.1198
更新日期:1999-04-01 00:00:00
abstract::Serum levels of a high molecular weight circulating antigen KL-6, detected by means of a sandwich assay using a monoclonal antibody KL-6 against a sialylated carbohydrate antigen, were evaluated for usefulness in monitoring the activity of interstitial pneumonitis. Abnormally high levels of KL-6 antigen were observed ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.96.1.68
更新日期:1989-07-01 00:00:00
abstract:STUDY OBJECTIVES:To determine the cause of pulmonary hypertension (PH) in systemic sclerosis (SSc) patients since PH can occur because of pulmonary arteriopathy, pulmonary parenchymal destruction, and left ventricular cardiac dysfunction. DESIGN AND SETTING:Consecutive case series in a university hospital. PATIENTS:N...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.4.1077
更新日期:2000-10-01 00:00:00
abstract::Tracheal bronchus is a common anomaly that occurs in approximately 2% of people. Two children with multiple medical problems which led to endotracheal intubation are described. The hospital course for each child was complicated by persistent right upper lobe atelectasis. The presence of a tracheal bronchus was not rec...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.113.2.537
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVES:To gain more knowledge of changes in main pulmonary artery flow and right ventricular mass and volumes in patients with pulmonary hypertension during epoprostenol therapy. METHODS:Eleven patients (9 women) were evaluated before the start of therapy and every 4 months thereafter. Right and left ventricular v...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.2.572
更新日期:2004-02-01 00:00:00
abstract::The hypothetic benefit of CPAP on cardiac performance and on a reduction in VO2 was tested in a patient before heart transplantation after acute myocardial infarction using continuous SvO2 monitoring. The CPAP added to inotropic support (enoximone plus dobutamine) and intraaortic balloon pumping dramatically increased...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.99.2.512
更新日期:1991-02-01 00:00:00
abstract::As of December 1975, there had been 5 to 8 1/2 years of observation on 263 patients with bacteriologically proven tuberculosis who were initially admitted to a general hospital and were treated largely as outpatients by community physicians from July 1967 through December 1970. Ten patients died during hospitalization...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.74.1.19
更新日期:1978-07-01 00:00:00
abstract::Lung volume reduction surgery (LVRS) is being evaluated in the treatment of emphysema. The proposed mechanisms of improvement are increased elastic recoil of the lung and improved mechanical efficiency of the muscles of respiration. We report a unique patient with emphysema who developed a giant bulla 3 years subseque...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.6.1809
更新日期:1999-12-01 00:00:00
abstract:STUDY OBJECTIVE:To examine the relation between left atrial (LA) function and exercise performance. DESIGN AND SETTING:Retrospective study at a referral cardiopulmonary exercise laboratory in a university hospital. PATIENTS:Forty-one patients with recent myocardial infarction. INTERVENTIONS:M-mode echocardiography a...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.111.4.922
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:The objective of the present study was to compare antibiotic prescribing practices and survival in the ICU for patients with pneumococcal severe community-acquired pneumonia (SCAP) between 2000 and 2013. METHODS:This was a matched case-control study of two prospectively recorded cohorts in Europe. Eighty pat...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.13-1531
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Induced sputum cytology and protein biomarkers can be used to assess airways inflammation. Increases in sputum iron have been described in inflammatory lung disease. We hypothesized that other sputum metals may be affected by airways inflammation and investigated their potential value as biomarkers. METHODS...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.09-1047
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:There is a need for a more complete classification system of lung cancer. To address this issue, we assessed whether the new staging could differentiate patients with early-stage cancers who have poorer prognosis and improve the unbalanced patient numbers with overlapping prognoses arising from the current T...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.06-1950
更新日期:2007-07-01 00:00:00
abstract:STUDY OBJECTIVE:To validate a noninvasive first-pass radionuclide ventriculographic (FPRV) measurement of maximum cardiac output (Qv) during exercise. DESIGN:Comparison of Qv to that measured by the Fick principle (Qf) at peak exercise. SETTING:Academic cardiopulmonary exercise laboratory. PATIENTS:Seventy-eight con...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.114.2.457
更新日期:1998-08-01 00:00:00
abstract::Pulmonary disease due to talc, a group of hydrous magnesium silicates, is almost exclusively encountered after occupational exposure. One form of this rare disorder is talc granulomatosis. In varying degrees, hypercalcemia is typical of granulomatous disease but has not yet been reported in talcosis. We report the cas...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.4.1195
更新日期:2000-04-01 00:00:00
abstract:STUDY OBJECTIVES:Although percutaneous transluminal coronary angioplasty (PTCA) is known to have beneficial effects on exercise capacity, its effects on the cardiovascular response during the onset of exercise have not been clarified. The present study was undertaken to determine the effects of PTCA on the kinetics of ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.2.329
更新日期:2000-08-01 00:00:00
abstract::Cardiorespiratory values were measured in ten patients with severe respiratory failure on volume controlled and pressure controlled ventilation. Tidal volume, respirator rate, PEEP, auto-PEEP, inspiratory:expiratory ratio (1:2) and FIo2 were maintained at the same value for both ventilatory modalities. Changing from V...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.6.1445
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND:The clinical course of idiopathic pulmonary fibrosis (IPF) is characterized by progressive decline in lung function and eventual mortality. We sought to determine if future declines in pulmonary function, mortality, or both can be predicted from prior trends in pulmonary function tests (PFTs). METHODS:Data ...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.13-0844
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Asthma morbidity and mortality are higher in the United States for African-American (AA) children when compared to European-American (EA) children. STUDY OBJECTIVES:To explore racial differences in physiologic factors associated with pediatric asthma severity. DESIGN:Cross-sectional. METHODS:We analyzed d...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.5.1336
更新日期:2000-05-01 00:00:00
abstract::Previous studies have described oxygen delivery (DO2) and oxygen consumption (VO2) relationships in patients with ARDS and other acute diseases that suggest occasions when VO2 may be dependent on the supply of oxygen, ie, DO2. We studied 127 postoperative patients who developed ARDS to evaluate the relationship of DO2...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.3.906
更新日期:1992-09-01 00:00:00
abstract::We encountered a clinical problem in a young man who presented with a left upper lobe mass and a diffuse reticular-nodular infiltrate. We thought we had appropriately applied Murphy's Law (the famed bank robber who "went where the money is"), and Ockham's Razor (the philosopher William of Ockham [1285 to 1349]-"Entiti...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.105.6.1864
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2019.09.028
更新日期:2020-01-01 00:00:00
abstract::The toxic-oil syndrome (TOS) is a multisystem disorder whose etiology and pathogenesis are as yet unknown. Lung alterations persist in a significant number of TOS patients due to the underlying vascular lesion. Computer-assisted 67Ga scanning and bronchoalveolar lavage (BAL) studies were performed in 14 TOS patients w...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.88.3.398
更新日期:1985-09-01 00:00:00
abstract::Ventilation and gas exchange were studied during sleep and incremental treadmill exercise in 19 patients with severe stable COPD with the primary aim of comparing the pathophysiology of oxygen desaturation in the two conditions. A secondary aim was to determine whether exercise studies could aid in the prediction of s...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.109.2.387
更新日期:1996-02-01 00:00:00
abstract:STUDY OBJECTIVES:The physicians who initially evaluate patients with non-small cell lung cancer (NSCLC) strongly impact the course of therapy. Their beliefs in treatment and prognosis may contribute to practices of variable quality and appropriateness. We sought to better describe beliefs among pulmonologists and thora...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.1.129
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:Physician productivity, practice expense, resource allocation, facilities, staff, and malpractice are variables in medical practice profitability. The ongoing challenge of collecting reliable and consistent data created an opportunity in 2001 for the American College of Chest Physicians (ACCP) Practice Admin...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.130.3.885
更新日期:2006-09-01 00:00:00