The prevalence of exercise-induced bronchospasm among US Army recruits and its effects on physical performance.


STUDY OBJECTIVES:To measure the prevalence of exercise-induced bronchospasm (EIB) and to determine its effect on the physical performance response to training in otherwise healthy young adults. DESIGN:Observational, retrospective study. SETTING:Fort Jackson, SC, May to July 1998. PARTICIPANTS:One hundred thirty-seven ethnically diverse US Army recruits undergoing an 8-week Army basic training course. MEASUREMENTS AND RESULTS:Subjects underwent exercise challenge testing at the end of basic training to evaluate for EIB (defined as a decrease in FEV(1) of > or = 15%, 1 or 10 min after running to peak oxygen uptake on a treadmill). Those subjects who were unable to run to peak oxygen uptake, or who were unable to perform two baseline FEV(1) maneuvers the results of which were within 5% of each other, were excluded from analysis. We measured peak oxygen uptake on a treadmill and the scores achieved on the components of the US Army physical fitness test (APFT). Of 137 subjects, 121 (58 men and 63 women) met our inclusion criteria. Eight subjects (7%) had EIB. Subjects who experienced EIB and unaffected control subjects both showed statistically significant gains in performance on the APFT events during basic training. At the end of basic training, peak oxygen uptake levels and APFT event scores were not significantly different between subjects with EIB and unaffected control subjects. CONCLUSIONS:Seven percent of the US Army recruits who were tested had EIB, but this did not hinder their physical performance gains during basic training. EIB per se should not be an absolute reason to exclude individuals from employment in jobs with heavy physical demands.






Sonna LA,Angel KC,Sharp MA,Knapik JJ,Patton JF,Lilly CM




Has Abstract


2001-06-01 00:00:00
















  • Subacute rupture of the left ventricular free wall after acute myocardial infarction. Three cases of long-term survival without emergency surgical repair.

    abstract::Rupture of the left ventricular free wall after acute myocardial infarction (AMI) has been regarded as uniformly fatal unless emergency surgical repair is performed. Among 2,862 patients admitted with AMI to our ICU during the last 8 years, 107 patients developed rupture of the left ventricular free wall. Twenty-nine ...


    pub_type: 杂志文章


    authors: Blinc A,Noc M,Pohar B,Cernic N,Horvat M

    更新日期:1996-02-01 00:00:00

  • Outcome of patients with idiopathic pulmonary fibrosis admitted to the ICU for respiratory failure.

    abstract:STUDY OBJECTIVES:To analyze the outcome of acute respiratory failure (ARF) in patients with idiopathic pulmonary fibrosis (IPF), and to evaluate the benefits of invasive and noninvasive mechanical ventilation (MV). DESIGN:Retrospective study. SETTING:University hospital. PATIENTS:Fifteen consecutive patients with IP...


    pub_type: 杂志文章


    authors: Blivet S,Philit F,Sab JM,Langevin B,Paret M,Guérin C,Robert D

    更新日期:2001-07-01 00:00:00

  • Outcomes in post-ICU mechanical ventilation: a therapist-implemented weaning protocol.

    abstract:BACKGROUND:Therapist-implemented protocols have been used to extubate or wean patients in the ICU setting. Barlow Respiratory Hospital (BRH) functions as a center for weaning patients from prolonged mechanical ventilation (PMV) in the post-ICU setting of a long-term acute-care (LTAC) facility. A therapist-implemented p...


    pub_type: 杂志文章


    authors: Scheinhorn DJ,Chao DC,Stearn-Hassenpflug M,Wallace WA

    更新日期:2001-01-01 00:00:00

  • Spinal cord ischemia resulting in paraplegia following extrapleural pneumonectomy.

    abstract::A patient undergoing radical extrapleural pneumonectomy for epithelioid malignant mesothelioma developed acute paraplegia postoperatively related to long-segment spinal cord ischemia. The usual area of concern for this complication is the T9 to T12 area where the artery of Adamkiewicz is most likely to originate. In t...


    pub_type: 杂志文章


    authors: Ural K,Jakob K,Lato S,Gilly G,Landreneau R

    更新日期:2014-08-01 00:00:00

  • Legionnaires disease and HIV infection.

    abstract:STUDY OBJECTIVES:To compare the outcome of Legionnaires disease (LD) in patients with and without HIV infection. DESIGN:Retrospective review of clinical charts. SETTING:Six hundred-bed university hospital. PATIENTS:We studied the clinical findings of 64 patients without HIV and 15 patients with HIV. Patients with a ...


    pub_type: 杂志文章


    authors: Pedro-Botet ML,Sabrià M,Sopena N,García-Núñez M,Dominguez MJ,Reynaga E,Rey-Joly C

    更新日期:2003-08-01 00:00:00

  • Electrolyte disturbances in patients with chronic, stable asthma: effect of therapy.

    abstract:OBJECTIVE:To determine the prevalence of electrolyte disturbances in patients with chronic, stable asthma, and to assess whether the therapeutic agents used to treat chronic asthma have an effect on abnormal electrolyte levels. DESIGN:Prospective, hospital-based, cross-sectional study. SETTING:University teaching hos...


    pub_type: 杂志文章


    authors: Alamoudi OS

    更新日期:2001-08-01 00:00:00

  • Emphysema presence, severity, and distribution has little impact on the clinical presentation of a cohort of patients with mild to moderate COPD.

    abstract:BACKGROUND:Phenotypic characterization of patients with COPD may have potential prognostic and therapeutic implications. Available information on the relationship between emphysema and the clinical presentation in patients with COPD is limited to advanced stages of the disease. The objective of this study was to descri...


    pub_type: 杂志文章


    authors: de Torres JP,Bastarrika G,Zagaceta J,Sáiz-Mendiguren R,Alcaide AB,Seijo LM,Montes U,Campo A,Zulueta JJ

    更新日期:2011-01-01 00:00:00

  • Nerve growth factor in serum and lymphocyte culture in pigeon fanciers' acute hypersensitivity pneumonitis.

    abstract:BACKGROUND:Nerve growth factor (NGF) is a neurotrophic cytokine with immunomodulatory activity. NGF contributes to neurogenic inflammation and has been described in asthma and idiopathic pulmonary fibrosis. OBJECTIVES:To identify and quantify NGF in serum and peripheral blood lymphocyte cultures from pigeon fanciers, ...


    pub_type: 杂志文章


    authors: McSharry CP,Fraser I,Chaudhuri R,Anderson K,Bourke SJ,Thomson NC,Boyd G

    更新日期:2006-07-01 00:00:00

  • Interposed abdominal compressions and carotid blood flow during cardiopulmonary resuscitation. Support for a thoracoabdominal unit.

    abstract::To determine if the timing of interposed abdominal compressions (IAC) affects the augmented blood flow during this form of cardiopulmonary resuscitation (CPR), we performed early-onset or late-onset abdominal compressions at three vascular volumes in nine dogs. Early-onset IAC began immediately following chest compres...


    pub_type: 杂志文章


    authors: Einagle V,Bertrand F,Wise RA,Roussos C,Magder S

    更新日期:1988-06-01 00:00:00

  • Effect of inhaled corticosteroid therapy on CT scan-estimated airway dimensions in a patient with chronic bronchitis related to ulcerative colitis.

    abstract::CT scanning allows assessment of airway-wall thickness and is useful for diagnosing and assessing various lung diseases, including asthma and COPD. Several studies have reported that CT scan-estimated dimensions are positively correlated with pulmonary function test results and a positive response to treatment. Howeve...


    pub_type: 杂志文章


    authors: Hamada S,Ito Y,Imai S,Oguma T,Niimi A,Mishima M

    更新日期:2011-04-01 00:00:00

  • Complete resolution of roentgenographic changes in a patient with pulmonary histiocytosis X.

    abstract::A smoker presented with pleuritic chest pain and was found to have reticulonodular interstitial opacities on chest x-ray film. Open lung biopsy revealed changes consistent with histiocytosis X, a disease seen almost exclusively in smokers. Smoking cessation was recommended, and the patient complied. A chest x-ray film...


    pub_type: 杂志文章


    authors: Von Essen S,West W,Sitorius M,Rennard SI

    更新日期:1990-09-01 00:00:00

  • Serial fiberoptic bronchoscopic observations of endobronchial tuberculosis before and early after antituberculosis chemotherapy.

    abstract:STUDY OBJECTIVE:To evaluate the antituberculous treatment responsiveness of endobronchial tuberculosis in the different stages of evolution. DESIGN:A prospective study before and after trial with 9 months of antituberculosis chemotherapy without steroid. PATIENTS AND INTERVENTION:One hundred thirty-six endobronchial ...


    pub_type: 杂志文章


    authors: Kim YH,Kim HT,Lee KS,Uh ST,Cung YT,Park CS

    更新日期:1993-03-01 00:00:00

  • A combined modality approach to recurrent cardiac sarcoma resulting in a prolonged remission: a case report.

    abstract::We report a case of cardiac fibrosarcoma that was treated with cardiac tumor resection, chemotherapy, cardiac explantation, tumor repeat resection, and autotransplantation followed by external beam irradiation. The patient was able to achieve clinical remission and remained disease free > 2 years after the initial dia...


    pub_type: 杂志文章


    authors: Mery GM,Reardon MJ,Haas J,Lazar J,Hindenburg A

    更新日期:2003-05-01 00:00:00

  • Lung volume reduction surgery for emphysema.

    abstract::There has been dramatic resurgence of interest in surgical treatment of emphysema, particularly "lung volume reduction" procedures. Recent studies have demonstrated improvements in pulmonary function, lung mechanics, exercise tolerance, and quality of life in selected patients following volume reduction procedures. Ho...


    pub_type: 杂志文章,评审


    authors: Brenner M,Yusen R,McKenna R Jr,Sciurba F,Gelb AF,Fischel R,Swain J,Chen JC,Kafie F,Lefrak SS

    更新日期:1996-07-01 00:00:00

  • Biochemical response to treatment of bone hyperresorption in chronically critically ill patients.

    abstract:STUDY OBJECTIVE:The chronically critically ill (CCI) are a subgroup of critically ill patients who have survived an acute critical illness but remain profoundly debilitated and ventilator dependent. We have previously shown that CCI patients have a very high prevalence of bone hyperresorption. The objective of this pre...


    pub_type: 杂志文章


    authors: Nierman DM,Mechanick JI

    更新日期:2000-09-01 00:00:00

  • Left atrial myxoma and acute myocardial infarction. A dangerous duo in the thrombolytic agent era.

    abstract::Systemic embolization is a common complication of left atrial myxoma; however, coronary embolism leading to acute myocardial infarction is rare. The use of echocardiography has increased the detection of intracardiac tumors when signs and symptoms are not evident. Echocardiography is the diagnostic procedure of choice...


    pub_type: 杂志文章


    authors: Abascal VM,Kasznica J,Aldea G,Davidoff R

    更新日期:1996-04-01 00:00:00

  • Metastatic malignant melanoma presenting clinically as obstruction of the right ventricular inflow and outflow tracts. Characterization by magnetic resonance imaging.

    abstract::Metastatic disease involving the heart may present in a variety of fashions. A patient with melanoma metastatic to the right ventricle which was diagnosed clinically by evidence of recent onset of right ventricular inflow and outflow tract obstruction is described. Important information regarding the extent of the met...


    pub_type: 杂志文章


    authors: Emmot WW,Vacek JL,Agee K,Moran J,Dunn MI

    更新日期:1987-08-01 00:00:00

  • Clinical characteristics and outcome of severe melioidosis requiring intensive care.

    abstract:STUDY OBJECTIVE:To describe the clinical characteristics and outcome of patients with severe melioidosis requiring intensive care. DESIGN:Retrospective chart review. SETTING:Two ICUs from a tertiary-care teaching hospital. PATIENTS:Twenty-seven adult ICU patients with microbiologically documented melioidosis. INTER...


    pub_type: 杂志文章


    authors: Chan KP,Low JG,Raghuram J,Fook-Chong SM,Kurup A

    更新日期:2005-11-01 00:00:00

  • Diaphragmatic motion studied by m-mode ultrasonography: methods, reproducibility, and normal values.

    abstract:BACKGROUND:Although diaphragmatic motion is readily studied by ultrasonography, the procedure remains poorly codified. The aim of this prospective study was to determine the reference values for diaphragmatic motion as recorded by M-mode ultrasonography. METHODS:Two hundred ten healthy adult subjects (150 men, 60 wome...


    pub_type: 杂志文章


    authors: Boussuges A,Gole Y,Blanc P

    更新日期:2009-02-01 00:00:00

  • N-terminal pro-brain natriuretic peptide and renal insufficiency as predictors of mortality in pulmonary hypertension.

    abstract:BACKGROUND:N-terminal pro-brain natriuretic peptide (NT-proBNP) is a byproduct of the brain natriuretic peptide (BNP) that was shown to be of prognostic value in pulmonary hypertension (PH). The role of NT-proBNP in PH has to be determined, especially under the influence of renal impairment that might lead to an accumu...


    pub_type: 杂志文章


    authors: Leuchte HH,El Nounou M,Tuerpe JC,Hartmann B,Baumgartner RA,Vogeser M,Muehling O,Behr J

    更新日期:2007-02-01 00:00:00

  • Pulmonary Hypertension in Parenchymal Lung Diseases: Any Future for New Therapies?

    abstract::Pulmonary hypertension (PH) due to chronic lung disease is associated with a poor prognosis, regardless of the underlying respiratory condition. Updated PH guidelines recommend optimal treatment of the underlying lung disease, including long-term oxygen therapy, in patients with chronic hypoxemia despite the lack of r...


    pub_type: 杂志文章,评审


    authors: Harari S,Elia D,Humbert M

    更新日期:2018-01-01 00:00:00

  • Calcified plaque in the superior portion of the major fissure. An unusual manifestation of asbestos exposure.

    abstract::Parietal pleural plaque is a well-recognized sign of exposure to asbestos. Visceral pleural involvement is an uncommon manifestation, and calcified visceral pleural plaques are rare. Those reported have been in the minor fissure and inferior major fissure. We describe a unique calcified plaque in the superior major fi...


    pub_type: 杂志文章


    authors: Rupp SB,Jolles H

    更新日期:1989-12-01 00:00:00

  • Thomas A. Neff lecture. Application of expression profiling to the developing lung: identification of putative regulatory networks controlling matrix production.

    abstract::If we hope to repair damaged lung tissue associated with a variety of acquired and developmental diseases, we must first gain a full appreciation of normal lung development. As an approach, we have utilized Affymetrix (Santa Clara, CA) high-density, oligonucleotide-based microarrays to generate an expression profile o...




    authors: Mariani TJ,Shapiro SD

    更新日期:2002-03-01 00:00:00

  • Tricuspid atresia. A review of 68 cases.

    abstract::Sixty-eight patients with tricuspid atresia were seen at Indiana University during the past 30 years. Long term survivors treated without operation emerged from our review. In these, there was a combination of tricuspid atresia and transposition of the great vessels. ...


    pub_type: 杂志文章


    authors: Shariatzadeh AN,King H,Girod D,Shumacker HB

    更新日期:1977-04-01 00:00:00

  • Activation of bronchial epithelial cells in smokers without airway obstruction and patients with COPD.

    abstract:STUDY OBJECTIVE:The aim of this study was to investigate the basal level as well as the tumor necrosis factor (TNF)-alpha- and interferon (IFN)-gamma-induced expression and release of the neutrophil chemoattractants interleukin (IL)-8 and growth-related oncogene (GRO)-alpha in primary bronchial epithelial cells (PBECs)...


    pub_type: 杂志文章


    authors: Schulz C,Krätzel K,Wolf K,Schroll S,Köhler M,Pfeifer M

    更新日期:2004-05-01 00:00:00

  • Preparing for pulmonary resection: preoperative evaluation of patients.

    abstract::Preoperative evaluation of patients being considered for pulmonary resection is a common practice for both pulmonologists and internists. Traditionally, preoperative evaluation of this population has entailed identifying patients in whom pulmonary resection carries an unacceptably high risk of morbidity and mortality....


    pub_type: 杂志文章,评审


    authors: Reilly JJ

    更新日期:1997-10-01 00:00:00

  • Propranolol-induced urticaria: successful therapy with tolamolol.

    abstract::Urticaria with systemic effects occurred in a patient being treated with propranolol and was reproducible upon rechallenge with the drug; Successful beta-adrenergic blocking therapy was achieved using a new agent, tolamolol, with no evidence of any adverse effects. ...


    pub_type: 杂志文章


    authors: Seides SF,Ruskin JN,Damato AN

    更新日期:1975-04-01 00:00:00

  • The effect of body mass index on patient outcomes in a medical ICU.

    abstract:STUDY OBJECTIVES:To examine the effect of patient body mass index (BMI) on outcome in intensive care. DESIGN:In a prospective study, the patients were classified into groups based on the calculated BMI, as follows: BMI < 19.0 (n = 350), > or = 19.0 and < 25.0 (n = 663), > or = 25.0 and < 29.9 (n = 585), > or = 30.0 an...


    pub_type: 杂志文章


    authors: Ray DE,Matchett SC,Baker K,Wasser T,Young MJ

    更新日期:2005-06-01 00:00:00

  • Effect of Balloon Pulmonary Angioplasty on Respiratory Function in Patients With Chronic Thromboembolic Pulmonary Hypertension.

    abstract:BACKGROUND:Balloon pulmonary angioplasty (BPA) in chronic thromboembolic pulmonary hypertension (CTEPH) improves hemodynamics and exercise capacity. However, its effect on respiratory function is unclear. Our objective was to investigate the effect of BPA on respiratory function. METHODS:We enrolled patients with inop...


    pub_type: 杂志文章


    authors: Akizuki M,Serizawa N,Ueno A,Adachi T,Hagiwara N

    更新日期:2017-03-01 00:00:00

  • Safety of long-term treatment with HFA albuterol.

    abstract:BACKGROUND:Chlorofluorocarbons (CFCs) used as propellants in metered-dose inhalers deplete stratospheric ozone, which results in serious public health concerns. Albuterol has been reformulated in the non-ozone-depleting propellant, hydrofluoroalkane-134a (HFA albuterol). OBJECTIVES:The primary objective was to compare...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Ramsdell JW,Klinger NM,Ekholm BP,Colice GL

    更新日期:1999-04-01 00:00:00