Familial type II hyperlipoproteinemia with coronary heart disease: effect of diet-colestipol-nicotinic acid treatment.

Abstract:

:Heterozygous familial type II hyperlipoproteinemia (F type II) is primarily manifested in hypercholesterolemia (due to low density lipoprotein-cholesterol [LDL-C] elevation) and premature coronary heart disease (CHD). We studied sequentially the effects of low cholesterol-low saturated fat-low simple carbohydrate diet; diet and colestipol, 30 g/day; and diet, colestipol, plus nicotinic acid (NA) 3 to 7 g/day on plasma cholesterol (Ch), LDL-C, triglyceride (TG), high density lipoprotein-cholesterol (HDL-C) and angiographically documented coronary arterial lesions of 32 F type II patients. Effective control of F type II resulted in arresting the progression of angiographically demonstrated coronary arterial lesions.

journal_name

Chest

journal_title

Chest

authors

Kuo PT,Kostis JB,Moreyra AE,Hayes JA

doi

10.1378/chest.79.3.286

subject

Has Abstract

pub_date

1981-03-01 00:00:00

pages

286-91

issue

3

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)61191-1

journal_volume

79

pub_type

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