Abstract:
:Twenty-one patients with malignant pleural effusion (MPE) were prospectively entered into a nonrandomized, single-armed study to evaluate the efficacy and safety of recombinant interferon (IFN) alpha-2b (INTRON A; Schering-Plough; Kenilworth, NJ) as an intrapleural palliative agent. From March 1989 through February 1993 (48 months), 21 patients were entered into the study. No symptomatic effusion recurred and no substantial side effects were associated with treatment. This suggests recombinant IFN alpha-2b represents a safe and effective intrapleural agent for the palliation of MPE.
journal_name
Chestjournal_title
Chestauthors
Wilkins HE 3rd,Connolly MM,Grays P,Marquez G,Nelson Ddoi
10.1378/chest.111.6.1597subject
Has Abstractpub_date
1997-06-01 00:00:00pages
1597-9issue
6eissn
0012-3692issn
1931-3543pii
S0012-3692(15)47048-5journal_volume
111pub_type
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