Recombinant interferon alpha-2b in the management of malignant pleural effusions.

Abstract:

:Twenty-one patients with malignant pleural effusion (MPE) were prospectively entered into a nonrandomized, single-armed study to evaluate the efficacy and safety of recombinant interferon (IFN) alpha-2b (INTRON A; Schering-Plough; Kenilworth, NJ) as an intrapleural palliative agent. From March 1989 through February 1993 (48 months), 21 patients were entered into the study. No symptomatic effusion recurred and no substantial side effects were associated with treatment. This suggests recombinant IFN alpha-2b represents a safe and effective intrapleural agent for the palliation of MPE.

journal_name

Chest

journal_title

Chest

authors

Wilkins HE 3rd,Connolly MM,Grays P,Marquez G,Nelson D

doi

10.1378/chest.111.6.1597

subject

Has Abstract

pub_date

1997-06-01 00:00:00

pages

1597-9

issue

6

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)47048-5

journal_volume

111

pub_type

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