Ostium primum defect in the adult: postoperative follow-up studies.

abstract：:Phosphodiesterase 4 (PDE4) is a major cyclic adenosine-3',5'-monophosphate-metabolizing enzyme in immune and inflammatory cells, airway smooth muscle, and pulmonary nerves. Selective inhibitors of this enzyme have been available for a number of years and show a broad spectrum of activity in animal models of COPD and a...

journal_title：Chest

authors： Sturton G,Fitzgerald M

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The synthetic peptide solnatide is a novel pharmacologic agent that reduces extravascular lung water, blunts reactive oxygen species production, and improves lung function due to its ability to directly activate the epithelial sodium channel. The goal of this study was to investigate the effect of solnatide ...

journal_title：Chest

authors： Zhou Q,Wang D,Liu Y,Yang X,Lucas R,Fischer B

更新日期：2017-03-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the relationship between obstructive sleep apnea (OSA) and ventilatory responsiveness to carbon dioxide in both men and women. DESIGN:An analysis of 219 patients referred to an university-based sleep center between 1989 to 1994 was conducted (104 with OSA and 115 without OSA; 43 women and 1...

journal_title：Chest

authors： Sin DD,Jones RL,Man GC

更新日期：2000-02-01 00:00:00

abstract：:A case is reported of 38-year-old woman with chest pain attributed to a left lung sarcoidosis mass. The mass failed to diminish and symptoms failed to resolve with systemic corticosteroid therapy. CT-guided direct intralesional transthoracic injection of dexamethasone resulted in resolution of the patient's symptoms a...

journal_title：Chest

authors： Judson MA,Uflacker R

更新日期：2001-07-01 00:00:00

abstract：STUDY OBJECTIVES:We sought to compare arterial oxygen partial pressure (PaO2) relationships between a 15.1% hypoxia inhalation test (HIT) at sea level and a hypobaric chamber exposure equivalent to 2,438 m (8,000 feet) of altitude above sea level in patients with chronic obstructive pulmonary disease (COPD) and healthy...

journal_title：Chest

authors： Dillard TA,Moores LK,Bilello KL,Phillips YY

更新日期：1995-02-01 00:00:00

abstract：:Portopulmonary hypertension (PPHTN) is an uncommon complication of advanced liver disease. Epoprostenol has been effective in the treatment of PPHTN and has been used as a bridge to orthotopic liver transplantation (OLT). The role of OLT in the reversal of PPHTN is unclear. We report a case of severe PPHTN (mean pulmo...

journal_title：Chest

authors： Rafanan AL,Maurer J,Mehta AC,Schilz R

更新日期：2000-11-01 00:00:00

abstract：STUDY OBJECTIVES:To quantify the snoring sound intensity levels generated by individuals during polysomnographic testing and to examine the relationships between acoustic, polysomnographic, and clinical variables. DESIGN:The prospective acquisition of acoustic and polysomnographic data with a retrospective medical cha...

journal_title：Chest

authors： Wilson K,Stoohs RA,Mulrooney TF,Johnson LJ,Guilleminault C,Huang Z

更新日期：1999-03-01 00:00:00

abstract：:The value of home spirometry in detecting acute lung rejection and opportunistic infections was studied in 15 heart-lung transplant recipients over a six-month period. The patients measured their FEV1 and FVC twice daily at home using a portable turbine spirometer. The records were then reviewed in relation to the res...

journal_title：Chest

authors： Otulana BA,Higenbottam T,Ferrari L,Scott J,Igboaka G,Wallwork J

更新日期：1990-02-01 00:00:00

abstract：STUDY OBJECTIVE:To compare the efficacy of standard medical therapy (ST) and noninvasive mechanical ventilation additional to standard medical therapy in hypercapnic acute respiratory failure (HARF). DESIGN:Single center, prospective, randomized, controlled study. SETTING:Pulmonary medicine directed critical care uni...

journal_title：Chest

authors： Celikel T,Sungur M,Ceyhan B,Karakurt S

更新日期：1998-12-01 00:00:00

abstract：STUDY OBJECTIVES:Community-acquired pneumonia (CAP) is a widespread disease with important implications for health-care systems worldwide. This study investigated direct costs, treatment patterns, and outcomes associated with two patient cohorts hospitalized with CAP. DESIGN:The study design was naturalistic, prospect...

journal_title：Chest

authors： Bauer TT,Welte T,Ernen C,Schlosser BM,Thate-Waschke I,de Zeeuw J,Schultze-Werninghaus G

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Pulmonary disease due to Mycobacterium avium complex (MAC-PD) radiographically resembles that due to tuberculosis; it preferentially affects elderly white men with predisposing pulmonary disorders (PDPD). METHODS:Twenty-nine patients with MAC-PD were identified from a community-based population, and the med...

journal_title：Chest

authors： Reich JM,Johnson RE

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVES:To study the effects of augmentation of continuous positive airway pressure (CPAP) education and support on compliance and outcome in patients with obstructive sleep apnea (OSA). DESIGN:A randomized, controlled, parallel study of basic vs augmented CPAP education and support. SETTING:A university teaching ...

journal_title：Chest

authors： Hui DS,Chan JK,Choy DK,Ko FW,Li TS,Leung RC,Lai CK

更新日期：2000-05-01 00:00:00

abstract：:The assessment of the structure and function of the subvalvular apparatus (SVA) in patients with rheumatic mitral stenosis (MS) is complex, yet is of major importance prior to therapeutic decision making. Currently available methods of assessment are neither sufficiently accurate nor feasible. We review anatomic and f...

journal_title：Chest

authors： Turgeman Y,Atar S,Rosenfeld T

更新日期：2003-11-01 00:00:00

abstract：:A 75-year-old man with a history of resected colon carcinoma presented to his primary care physician because of a new onset of coughing. The patient had expectorated a small piece of solid tissue; pathologic examination of the tissue found it to be consistent with metastatic colon adenocarcinoma. After further work-up...

journal_title：Chest

authors： Zias EA,Owen RP,Borczuk A,Reichel J,Frater RW

更新日期：1998-01-01 00:00:00

abstract：:Recent studies have suggested that vasodilators may acutely improve pulmonary hemodynamics in patients with chronic obstructive pulmonary disease and cor pulmonale, but the effects of long-term therapy have not been assessed. We evaluated the hemodynamic and gas exchange effects of nitrendipine, a calcium channel bloc...

journal_title：Chest

authors： Rubin LJ,Moser K

更新日期：1986-01-01 00:00:00

abstract：:The self-expandable stainless steel stents (Gianturco, William Cook, Bjaeverskov, Denmark) used extensively in biliary ducts and the vascular system have recently been modified for use in the tracheobronchial tree. Between March 1991 and September 1992, six patients with unresectable tracheobronchial and mediastinal d...

journal_title：Chest

authors： Zannini P,Melloni G,Chiesa G,Carretta A

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:Analysis of laryngotracheoscopic findings of the upper airway tract following percutaneous tracheostomy using the technique according to Griggs. DESIGN:Retrospective cohort study PATIENTS:Nineteen of 32 long-term surviving patients (mean follow-up duration, 17 months; range, 11 to 23 months) underwent a mod...

journal_title：Chest

authors： Dollner R,Verch M,Schweiger P,Deluigi C,Graf B,Wallner F

更新日期：2002-07-01 00:00:00

abstract：:Heterozygous familial type II hyperlipoproteinemia (F type II) is primarily manifested in hypercholesterolemia (due to low density lipoprotein-cholesterol [LDL-C] elevation) and premature coronary heart disease (CHD). We studied sequentially the effects of low cholesterol-low saturated fat-low simple carbohydrate diet...

journal_title：Chest

authors： Kuo PT,Kostis JB,Moreyra AE,Hayes JA

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Much controversy persists regarding the place of statin drugs in the treatment of patients with COPD. This systematic review and meta-analysis sought to determine the clinical efficacy of statin therapy in COPD. METHODS:We searched MEDLINE, EMBASE, the Cochrane Database, and PubMed for relevant clinical stu...

journal_title：Chest

authors： Zhang W,Zhang Y,Li CW,Jones P,Wang C,Fan Y

更新日期：2017-12-01 00:00:00

abstract：:The efficacy of a nasopharyngeal tube was evaluated in 44 patients with obstructive sleep apnea syndrome. Twenty-four of these patients underwent repeated polysomnographic studies with the nasopharyngeal tube in place. They had a 62.3 percent decrease in apnea index and a 39.2 percent decrease in disordered breathing ...

journal_title：Chest

authors： Nahmias JS,Karetzky MS

更新日期：1988-12-01 00:00:00

abstract：:The clinical course of congestive heart failure (CHF) and mitral valve stenosis (MVS) is accompanied by episodes of dyspnea, wheezing, and cough, symptoms also observed in patients with bronchial hyperreactivity. However, it is still controversial whether bronchial hyperreactivity is demonstrable in patients with chro...

journal_title：Chest

authors： Brunnée T,Graf K,Kastens B,Fleck E,Kunkel G

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To ascertain the differences in smoking characteristics between a group of smokers with COPD and another group of healthy smokers, both of which were identified in a population-based epidemiologic study. DESIGN AND PARTICIPANTS:This is an epidemiologic, multicenter, population-based study conducted in seven ...

journal_title：Chest

authors： Jiménez-Ruiz CA,Masa F,Miravitlles M,Gabriel R,Viejo JL,Villasante C,Sobradillo V

更新日期：2001-05-01 00:00:00

abstract：:Patients with spinal muscle atrophy (SMA) who survive to adulthood experience a slow, continuous loss of motor function but typically have a normal life expectancy. These patients, however, require vigilance on the part of their health-care providers to reverse treatable disorders to maintain a satisfactory quality of...

journal_title：Chest

authors： Puruckherr M,Mehta JB,Girish MR,Byrd RP Jr,Roy TM

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:The "Dutch hypothesis" suggests that asthma and COPD have common genetic determinants. The serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) gene previously has been associated with COPD. We sought to determine whether SERPINE2 is associated with asthma ...

journal_title：Chest

authors： Himes BE,Klanderman B,Ziniti J,Senter-Sylvia J,Soto-Quiros ME,Avila L,Celedón JC,Lange C,Mariani TJ,Lasky-Su J,Hersh CP,Raby BA,Silverman EK,Weiss ST,DeMeo DL

更新日期：2011-09-01 00:00:00

abstract：:Hemodynamic and metabolic effects of methylprednisolone were investigated in a double-blind study of 28 patients with acute myocardial infarction (AMI), confirmed by unequivocal electrocardiographic and enzyme changes. Measurements were performed prior to and at 1.5, 3, 4, 4.5, 12 and 24 hours following infusion of me...

journal_title：Chest

authors： Henning RJ,Becker H,Vincent JL,Thijs L,Kalter E,Weil MH

更新日期：1981-02-01 00:00:00

abstract：:Closure of ventricular septal defects through the aortic valve annulus has been described for a variety of cardiac anomalies. This technique is most appropriate when simultaneous aortic valve replacement is anticipated. A continuous suture through the patch material may produce a purse-string effect upon the aortic va...

journal_title：Chest

authors： Stewart S

更新日期：1976-08-01 00:00:00

abstract：STUDY OBJECTIVE:To determine whether higher personnel intensive chest physical therapy can prevent the atelectasis that routinely follows cardiac valve surgery. DESIGN:Randomized, controlled trial. SETTING:Tertiary care hospital. PATIENTS:Seventy-eight patients undergoing elective cardiac valve surgery between Octob...

journal_title：Chest

authors： Johnson D,Kelm C,Thomson D,Burbridge B,Mayers I

更新日期：1996-03-01 00:00:00

abstract：:Since 1986, the Emergency Medical Treatment and Labor Act (EMTALA) has imposed an obligation on hospitals and physicians to evaluate and stabilize patients who present to a hospital ED seeking care. Available sanctions for noncompliance include fines, damages awarded in civil litigation, and exclusion from Medicare. E...

journal_title：Chest

authors： Hyman DA,Studdert DM

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The clinical course of idiopathic pulmonary fibrosis (IPF) is characterized by progressive decline in lung function and eventual mortality. We sought to determine if future declines in pulmonary function, mortality, or both can be predicted from prior trends in pulmonary function tests (PFTs). METHODS:Data ...

journal_title：Chest

authors： Schmidt SL,Tayob N,Han MK,Zappala C,Kervitsky D,Murray S,Wells AU,Brown KK,Martinez FJ,Flaherty KR

更新日期：2014-03-01 00:00:00

abstract：:Despite major advances in our understanding of the pathophysiologic processes leading to pulmonary arterial hypertension and recent developments in therapeutic approaches, the long-term prognosis for patients with pulmonary arterial hypertension remains unsatisfactory. Early detection and adequate clinical classificat...

journal_title：Chest

authors： Provencher S,Jais X,Yaici A,Sitbon O,Humbert M,Simonneau G

更新日期：2005-12-01 00:00:00