Hypercapnic ventilatory response in patients with and without obstructive sleep apnea: do age, gender, obesity, and daytime PaCO(2) matter?

abstract：:A newborn infant with severe respiratory distress from bilateral diaphragmatic paralysis caused by birth injury was successfully treated with nasal continuous positive airway pressure (CPAP). Improvement gradually occurred, and CPAP was discontinued after he was 23 days of age. This therapy has advantages over alterna...

journal_title：Chest

authors： Zajkowski EJ,Kravath RE

更新日期：1979-03-01 00:00:00

abstract：:This study compared the bronchodilator effect in experimental canine asthma of dyphylline administered by aerosol and intravenous routes in doses producing equivalent concentrations of the drug in the plasma. Pulmonary resistance (RL) was calculated from simultaneous measurements of pressure and flow during fixed-volu...

journal_title：Chest

authors： Hirshman CA,Lawyer C,Downes H,Farbood A,Rodgers R,Gerber N

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Lung cancer screening, despite its proven mortality benefit, remains vastly underutilized. Previous studies examined knowledge, attitudes, and beliefs to better understand the reasons underlying the low screening rates. These investigations may have limited generalizability because of traditional participant...

journal_title：Chest

authors： Monu J,Triplette M,Wood DE,Wolff EM,Lavallee DC,Flum DR,Farjah F

更新日期：2020-07-01 00:00:00

abstract：:We studied 15 nonsmoking, clinically stable asthmatic subjects aged 27 to 39 years to evaluate the potential cardiotoxic effects of combined use of a beta-adrenergic agonist drug and theophylline in the treatment of asthma. Subjects underwent a one-week washout period followed by two one-week periods of study receivin...

journal_title：Chest

authors： Coleman JJ,Vollmer WM,Barker AF,Schultz GE,Buist AS

更新日期：1986-07-01 00:00:00

abstract：:99mTechnetium macroaggregated albumin has successfully been used to define severe postoperative pulmonary vasoconstriction in a four-month-old boy with D-transposition of the great vessels who had undergone a Blalock-Hanlon surgical atrial septectomy. Radionuclide imaging documented clinically suspected pulmonary vaso...

journal_title：Chest

authors： Moodie DS,Levy JM,Kahn DR,Lieberman LM,Pastakia B

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVES:To investigate the time course and the relation to prognosis of coagulation and fibrinolytic abnormalities in patients with septic shock. PATIENTS AND METHODS:Forty-eight consecutive patients admitted to the medical ICU with the diagnosis of septic shock (diagnosed by defined criteria) were studied. Mortali...

journal_title：Chest

authors： Lorente JA,García-Frade LJ,Landín L,de Pablo R,Torrado C,Renes E,García-Avello A

更新日期：1993-05-01 00:00:00

abstract：:Itraconazole is a new orally active antifungal triazole with impressive activity against Aspergillus spp. Six patients with allergic bronchopulmonary aspergillosis (ABPA), aged 14 to 49 years, were treated with oral itraconazole (200 mg twice daily) for a mean of 3.9 months (range, one to six months; three patients co...

journal_title：Chest

authors： Denning DW,Van Wye JE,Lewiston NJ,Stevens DA

更新日期：1991-09-01 00:00:00

abstract：INTRODUCTION:Managed care, both via staff model health maintenance plans and nonstaff model plans, has become a major source of health-care funding in the United States. However, very little is known about the asthma-specific products and services offered by these plans. The purpose of this study is to examine the asth...

journal_title：Chest

authors： Nelson SG,Grant EN,Trubitt MJ,Foggs MB,Weiss KB

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Current treatment strategies for asthma and chronic obstructive pulmonary disease (COPD) emphasize the inhalation route, yet patients often misuse metered-dose inhalers (MDI). To address this problem, patient education by medical personnel has been recommended and a variety of alternate inhaler devices have ...

journal_title：Chest

authors： Hanania NA,Wittman R,Kesten S,Chapman KR

更新日期：1994-01-01 00:00:00

abstract：:Macrophages are the most abundant immune cell population in normal lung tissue and serve critical roles in innate and adaptive immune responses as well as the development of inflammatory airway disease. Studies in a mouse model of chronic obstructive lung disease and translational studies of humans with asthma and COP...

journal_title：Chest

authors： Byers DE,Holtzman MJ

更新日期：2011-09-01 00:00:00

abstract：:Simultaneous hemodynamic and blood gas measurements were performed in 26 hypertensive adults, who were cigarette smokers, before and after a 30-minute infusion of saralasin (5 microgram/kg/min) which is a highly specific competitive antagonist of angiotensin II (AII). The arterial pressure fell in nine, rose in seven ...

journal_title：Chest

authors： Mookherjee S,Obeid AI,Ashutosh K,Warner RA,Smulyan H

更新日期：1979-04-01 00:00:00

abstract：:A 10-year-old, 36-kg child with a malignant air leak who failed conventional mechanical ventilation and high-frequency jet ventilation was successfully treated with a neonatal high-frequency oscillatory ventilator for 31 days. Since the air leak resolved with minimal hemodynamic compromise, this technique may have app...

journal_title：Chest

authors： Mayes TC,Jefferson LS,David Y,Louis PT,Fortenberry JD

更新日期：1991-07-01 00:00:00

abstract：:Twenty-eight patients developed severe, progressive acute respiratory insufficiency despite aggressive application of conventional respiratory therapy. Application of increased PEEP (18 torr or greater) resulted in a significant decrease in QA/QT. Selection of the optimal levle of PEEP for each patient required seria...

journal_title：Chest

authors： Kirby RR,Downs JB,Civetta JM,Modell JH,Dannemiller FJ,Klein EF,Hodges M

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:In the current economic climate, hospitals and academic institutions demand that medical departments function in an efficient and cost-effective manner. Detailed business plans are necessary to build new clinical programs, and institutions have learned that new programs are associated with significant costs ...

journal_title：Chest

authors： Lunn W,Garland R,Gryniuk L,Smith L,Feller-Kopman D,Ernst A

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:We aimed to evaluate the availability and practice of spirometry, training of technicians, and spirometer features and maintenance in Spain in both primary care (PC) and secondary care (SC) centers. METHODS:We used a nationwide, cross-sectional, 36-item telephone survey of health-care centers in Spain to ta...

journal_title：Chest

authors： López-Campos JL,Soriano JB,Calle M,Encuesta de Espirometría en España (3E) Project.

更新日期：2013-08-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the efficacy of mass spirometry use for the detection of airflow obstruction in a high-risk population. DESIGN:Free spirometry was offered to smokers who were > 39 years of age with a smoking history of > 10 pack-years. Action was preceded by the dissemination of information on the causes ...

journal_title：Chest

authors： Zieliñski J,Bednarek M,Know the Age of Your Lung Study Group.

更新日期：2001-03-01 00:00:00

abstract：:Normal subjects were exposed to an aerosol of Escherichia coli endotoxin. Carbon monoxide diffusion (Dco), spirometry, blood neutrophils, white blood cells, and platelets were determined at various times thereafter. A significant decrease in Dco and an increase in blood neutrophils was found, with a maximum effect 4 t...

journal_title：Chest

authors： Herbert A,Carvalheiro M,Rubenowitz E,Bake B,Rylander R

更新日期：1992-10-01 00:00:00

abstract：:Metastatic disease involving the heart may present in a variety of fashions. A patient with melanoma metastatic to the right ventricle which was diagnosed clinically by evidence of recent onset of right ventricular inflow and outflow tract obstruction is described. Important information regarding the extent of the met...

journal_title：Chest

authors： Emmot WW,Vacek JL,Agee K,Moran J,Dunn MI

更新日期：1987-08-01 00:00:00

abstract：:We studied the value of pleural fluid neuron-specific enolase as a possible diagnostic marker for pleurisy of small cell lung cancer by using enzyme immunoassay. Pleural fluid NSE levels in 12 patients with carcinomatous pleurisy due to small cell lung cancer were compared with those in 37 patients with carcinomatous ...

journal_title：Chest

authors： Shimokata K,Niwa Y,Yamamoto M,Sasou H,Morishita M

更新日期：1989-03-01 00:00:00

abstract：STUDY OBJECTIVES:Whereas pulmonary rehabilitation reduces symptoms and improves the quality of life of patients with COPD and is recommended in management guidelines, few patients have access to rehabilitation services. The purpose of this study was to investigate the effectiveness of increasing access to selected comp...

journal_title：Chest

authors： Coultas D,Frederick J,Barnett B,Singh G,Wludyka P

更新日期：2005-10-01 00:00:00

abstract：:Acute chest syndrome complicating sickle cell anemia may progress to adult respiratory distress syndrome despite appropriate therapy. Extra-alveolar air leaks may complicate the care of these patients as conventional mechanical ventilation becomes increasingly difficult. We successfully treated a child with sickle cel...

journal_title：Chest

authors： Baird JS,Johnson JL,Escudero J,Powars DR

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of electrolyte disturbances in patients with chronic, stable asthma, and to assess whether the therapeutic agents used to treat chronic asthma have an effect on abnormal electrolyte levels. DESIGN:Prospective, hospital-based, cross-sectional study. SETTING:University teaching hos...

journal_title：Chest

authors： Alamoudi OS

更新日期：2001-08-01 00:00:00

abstract：:The pathogenesis and clinical manifestations of COPD are not restricted to pulmonary inflammation and structural remodeling. Rather, this disorder is associated with clinically significant systemic alterations in biochemistry and organ function. The systemic aspects of COPD include oxidative stress and altered circula...

journal_title：Chest

authors： Wouters EF,Creutzberg EC,Schols AM

更新日期：2002-05-01 00:00:00

abstract：:COPD is a significant public health challenge, notably set to become the third leading cause of death and fifth leading cause of chronic disability worldwide by the next decade. Skeletal muscle impairment is now recognized as a disabling, extrapulmonary consequence of COPD that is associated with reduced quality of li...

journal_title：Chest

authors： Taivassalo T,Hussain SN

更新日期：2016-05-01 00:00:00

abstract：STUDY OBJECTIVES:Patients with COPD have an increased sympathetic modulation and reduced baroreflex sensitivity (BRS). Therefore, we studied the effects of breathing 31% supplemental oxygen (SuppO(2)) on autonomic modulation in a group of COPD patients. DESIGN:We measured autonomic modulation before and during the adm...

journal_title：Chest

authors： Bartels MN,Gonzalez JM,Kim W,De Meersman RE

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Sleep apnea has major neurocognitive and cardiovascular and metabolic risks. Treatment of sleep apnea is suboptimal because of variable adherence to existing therapies. METHODS:This trial compared positive airway pressure adherence among patients who were provided active patient engagement (APE) technology ...

journal_title：Chest

authors： Malhotra A,Crocker ME,Willes L,Kelly C,Lynch S,Benjafield AV

更新日期：2018-04-01 00:00:00

abstract：:To determine if a regimen of intravenous and oral corticosteroids reduces the relapse rate after treatment of decompensated COPD in the ED, 30 patients were studied. Forty-five visits in which intravenous and oral corticosteroids were given (T visits) were compared with an equal number of matched visits in which they ...

journal_title：Chest

authors： Murata GH,Gorby MS,Chick TW,Halperin AK

更新日期：1990-10-01 00:00:00

abstract：STUDY OBJECTIVES:To assess exercise tolerance and determine the distinct role of cardiac, respiratory, or peripheral factors on it after delayed surgical repair in patients with tetralogy of Fallot. DESIGN:The aerobic exercise capacity of 15 adult patients (mean [+/- SD] age, 21 +/- 6; age range, 9 to 30 years) underg...

journal_title：Chest

authors： Ercisli M,Vural KM,Gokkaya KN,Koseoglu F,Tufekcioglu O,Sener E,Tasdemir O

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:To examine outcome and associated factors of acute respiratory failure (ARF) in non-HIV-related Pneumocystis pneumonia (PCP) in patients admitted to a medical ICU between 1995 and 2002. DESIGN:A retrospective review of medical records and an APACHE (acute physiology and chronic health evaluation) III databas...

journal_title：Chest

authors： Festic E,Gajic O,Limper AH,Aksamit TR

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Our study assessed the short-term effect of electrical muscle stimulation (EMS) of the lower extremities on the thenar muscle microcirculation of patients who are critically ill. METHODS:Twenty-nine hospital ICU patients (19 men; mean [+/- SD] age, 58 +/- 19 years; mean acute physiology and chronic health e...

journal_title：Chest

authors： Gerovasili V,Tripodaki E,Karatzanos E,Pitsolis T,Markaki V,Zervakis D,Routsi C,Roussos C,Nanas S

更新日期：2009-11-01 00:00:00