Hypercapnic ventilatory response in patients with and without obstructive sleep apnea: do age, gender, obesity, and daytime PaCO(2) matter?

abstract：:Persistent minor hemoptysis resulted from extensive granulation tissue on the main carina and adjacent bronchi due to frequent spraying of metered-dose inhaler (MDI)-generated aerosol medications directly into a permanent tracheostomy. Salbutamol, containing oleic acid, was considered the most likely cause. After an A...

journal_title：Chest

authors： Newhouse MT

更新日期：1999-01-01 00:00:00

abstract：:It is known that smoking affects the development and maintenance of certain types of granulomatous lung diseases. To explore this mechanism(s), we measured tumor necrosis factor (TNF)-alpha concentrations in the culture supernatants of lipopolysaccharide (LPS)-stimulated alveolar macrophages (AMs) in 13 healthy nonsmo...

journal_title：Chest

authors： Yamaguchi E,Itoh A,Furuya K,Miyamoto H,Abe S,Kawakami Y

更新日期：1993-02-01 00:00:00

abstract：:Paclitaxel, the first of the taxanes, has exhibited unique and encouraging single-agent activity in the treatment of non-small cell lung cancer (NSCLC). Yet, with single-agent response rates approaching 25%, it was logical to examine the impact of paclitaxel in combination chemotherapy regimens. In trials evaluating t...

journal_title：Chest

authors： Belani CP

更新日期：2000-04-01 00:00:00

abstract：:Actinomyces israelii is a rare cause of pericarditis. Infection spreads to pericardium from an intrathoracic focus. Branching gram-positive filaments are seen on microscopic examination of clinical specimens. Cultures should be performed under anaerobic conditions. Both surgical drainage and antibiotics (penicillin) a...

journal_title：Chest

authors： Schlossberg D,Franco-Jove D,Woodward C,Shulman J

更新日期：1976-05-01 00:00:00

abstract：:In rabbits, an experimental model of fat embolism was produced that simulates the course of events in the clinical situation. Small doses of fat-cell suspension (0.075 ml/kg of body weight), prepared by collagenase treatment of homologous adipose tissue, were injected intravenously. Concomitantly, hypovolemia was prod...

journal_title：Chest

authors： Cotev S,Rosenmann E,Eyal Z,Weinberg H,Shafrir E,Davidson JT

更新日期：1976-04-01 00:00:00

abstract：STUDY OBJECTIVE:To reevaluate whether it is possible to reliably differentiate malignant mediastinal lymph nodes from benign nodes by size, and to determine the frequency of metastases to normal-sized mediastinal lymph nodes that directly affects the sensitivity for detecting malignant mediastinal lymph nodes (N2 nodes...

journal_title：Chest

authors： Arita T,Matsumoto T,Kuramitsu T,Kawamura M,Matsunaga N,Sugi K,Esato K

更新日期：1996-10-01 00:00:00

abstract：:A number of general observations can be made from these recent studies. Lactate is a ubiquitous substance that is produced and removed from the body at all times, even at rest, both with and without the availability of oxygen. It is now recognized that lactate accumulates in the blood for several reasons, not just the...

journal_title：Chest

authors： Myers J,Ashley E

更新日期：1997-03-01 00:00:00

abstract：:The ipsilateral recurrence rate after the first spontaneous pneumothorax treated with tube thoracostomy is reported to be between 23 percent and 52 percent. The incidence of recurrence after the first recurrence is substantially higher. Chemical pleurodesis has been attempted to decrease the recurrence rate. Tetracycl...

journal_title：Chest

authors： Milanez JR,Vargas FS,Filomeno LT,Fernandez A,Jatene A,Light RW

更新日期：1994-10-01 00:00:00

abstract：:Because of its greater ease and rapidity of insertion, the percutaneous intraaortic balloon in many institutions has become the primary method for implementing counterpulsation. We report the results and complications of 113 attempted procedures in a variety of clinical settings. We had a high (93.8 percent) insertion...

journal_title：Chest

authors： Hauser AM,Gordon S,Gangadharan V,Ramos RG,Westveer DC,Garg AK,Timmis GC

更新日期：1982-10-01 00:00:00

abstract：STUDY OBJECTIVES:Whereas pulmonary rehabilitation reduces symptoms and improves the quality of life of patients with COPD and is recommended in management guidelines, few patients have access to rehabilitation services. The purpose of this study was to investigate the effectiveness of increasing access to selected comp...

journal_title：Chest

authors： Coultas D,Frederick J,Barnett B,Singh G,Wludyka P

更新日期：2005-10-01 00:00:00

abstract：:Pathologic obstruction of the proximal lumen and secondary atrophy of the media of the peripheral small pulmonary arteries were absolute operative contraindications in cases of VSD and/or PDA with severe pulmonary hypertension. Such patients who were operated on died with no decrease in pulmonary arterial pressure. Th...

journal_title：Chest

authors： Yamaki S,Mohri H,Haneda K,Endo M,Akimoto H

更新日期：1989-07-01 00:00:00

abstract：:Forty-four patients with newly discovered biopsy-proven pulmonary sarcoidosis in roentgenographic stage II (adenopathy and interstitial abnormalities) who also had abnormal pulmonary function (TLC and/or DCO less than 80 percent predicted) were assigned in alternate sequence to either a daily or alternate day predniso...

journal_title：Chest

authors： Spratling L,Tenholder MF,Underwood GH,Feaster BL,Requa RK

更新日期：1985-11-01 00:00:00

abstract：:These data suggest that the alveolar lining layer and lamellar body membranes contain the same saline-insoluble proteins, two of which are unusual in that they contain hydroxyproline and large amounts of glycine. Neither the function nor the origin of these glycopeptides has been established, and we are currently eval...

journal_title：Chest

authors： Passero MA,Bhattacharyya SN,Sahu S,Lynn WS

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify the CT scan features that predict patient outcome after reexpansion procedures in patients with the fibrotic stage of endobronchial TB. METHODS:We retrospectively enrolled 30 patients (four men, 26 women) aged 32 +/- 11 years who had lobar or whole-lung atelectasis ...

journal_title：Chest

authors： Lee JY,Yi CA,Kim TS,Kim H,Kim J,Han J,Kwon OJ,Lee KS,Chung MJ

更新日期：2010-08-01 00:00:00

abstract：:Aortic valve atresia is usually associated with hypoplasia of the left ventricle and mitral valve. We report a patient presenting aortic atresia with ventricular septal defect and a normally sized left ventricle. The electrocardiogram showed left axis deviation and left ventricular hypertrophy. The ventricular septal ...

journal_title：Chest

authors： Pellegrino PA,Thiene G

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in patients with COPD. METHODS:Serum SIRT1 protein of all samples was meas...

journal_title：Chest

authors： Yanagisawa S,Papaioannou AI,Papaporfyriou A,Baker JR,Vuppusetty C,Loukides S,Barnes PJ,Ito K

更新日期：2017-08-01 00:00:00

abstract：:Research on dominant oncogenes and tumor suppressor genes has characterized differences in genetic lesions between small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) and identified associations with clinical parameters. More than one half of all lung cancers contain a mutation of the p53 tumor suppre...

journal_title：Chest

authors： Johnson BE,Kelley MJ

更新日期：1993-01-01 00:00:00

abstract：:Symptom-limited supine bicycle exercise with radionuclide angiography was performed on 11 patients with severe mitral regurgitation (who were not receiving vasodilators), to assess changes in left ventricular volume, regurgitant fraction, forward flow and regurgitant flow during exercise. All patients were in normal s...

journal_title：Chest

authors： Lavie CJ,Lam JB,Gibbons RJ

更新日期：1989-11-01 00:00:00

abstract：STUDY OBJECTIVE:To compare the acute bronchodilatory effect of the long-acting beta2-agonist formoterol against the short-acting beta2-agonist (SABA) terbutaline during exercise-induced bronchoconstriction (EIB) in children with asthma. DESIGN:A randomized, double-blind, placebo-controlled, crossover study of the imme...

journal_title：Chest

authors： Hermansen MN,Nielsen KG,Buchvald F,Jespersen JJ,Bengtsson T,Bisgaard H

更新日期：2006-05-01 00:00:00

abstract：:The electrical impedance of a pulmonary mass was measured in 53 patients of whom 44 had primary lung cancer, 5 had metastatic lung tumor, and 4 had organizing pneumonia. Because biologic tissue can be regarded, electrically, to consist of extracellular resistance (Re), intracellular resistance (Ri), and the electrical...

journal_title：Chest

authors： Kimura S,Morimoto T,Uyama T,Monden Y,Kinouchi Y,Iritani T

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Work-related symptoms and disability due to respiratory disease are common and costly among working-age adults. To investigate this problem, we analyzed data on respiratory symptoms related to the workplace and occupational disability from the European Community Respiratory Health Survey (ECRHS). METHODS:Th...

journal_title：Chest

authors： Blanc PD,Burney P,Janson C,Torén K

更新日期：2003-09-01 00:00:00

abstract：:Although NCPAP is the most efficient nonsurgical treatment for patients with OSA, many patients do not accept sleeping with a nose mask. To determine the factors influencing acceptance, treatment with NCPAP was offered to 95 patients with an AHI greater than 15. After the first night on NCPAP, 47 of 65 patients decide...

journal_title：Chest

authors： Rauscher H,Popp W,Wanke T,Zwick H

更新日期：1991-10-01 00:00:00

abstract：:Disappointing results of surgery and postoperative adjuvant chemotherapy or chemoradiotherapy in stage IIIA (N2) lung cancer have led to a number of phase II trials of induction (neoadjuvant) chemotherapy given prior to surgery. Preliminary results of 2 such studies indicate that mitomycin, vinca alkaloid, and platinu...

journal_title：Chest

authors： Ginsberg RJ

更新日期：1993-04-01 00:00:00

abstract：:The literature contains many reports of the echocardiographic findings in left atrial myxoma and clot; however, descriptions of left ventricular thrombus or tumor are rare. We discuss here the echocardiographic findings in a patient with a large apical left ventricular thrombus which was confirmed both angiographicall...

journal_title：Chest

authors： DeJoseph RL,Shiroff RA,Levenson LW,Martin CE,Zelis RF

更新日期：1977-03-01 00:00:00

abstract：:We studied 15 nonsmoking, clinically stable asthmatic subjects aged 27 to 39 years to evaluate the potential cardiotoxic effects of combined use of a beta-adrenergic agonist drug and theophylline in the treatment of asthma. Subjects underwent a one-week washout period followed by two one-week periods of study receivin...

journal_title：Chest

authors： Coleman JJ,Vollmer WM,Barker AF,Schultz GE,Buist AS

更新日期：1986-07-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the role of microaspiration in gastroesophageal reflux-induced bronchoconstriction. DESIGN:Prospective study blinded to the subject. SETTING:Outpatient laboratory of a 908-bed university hospital. PARTICIPANTS:Thirty nonsmoking adults divided into two groups: asthmatics with reflux (AR), ...

journal_title：Chest

authors： Harding SM,Schan CA,Guzzo MR,Alexander RW,Bradley LA,Richter JE

更新日期：1995-11-01 00:00:00

abstract：STUDY OBJECTIVES:Small-cell lung cancer (SCLC) has an unfavorable prognosis, especially when the disease is extensive at presentation. Accurate staging procedures are therefore needed for treatment planning. Positron emission tomography (PET) is a modern noninvasive imaging technique, the value of which for the staging...

journal_title：Chest

authors： Hauber HP,Bohuslavizki KH,Lund CH,Fritscher-Ravens A,Meyer A,Pforte A

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial pneumonia and sometimes coexists with a histologic usual interstitial pneumonia (UIP) pattern. This study aimed to describe the distinct clinical features of PPFE with UIP pattern compared with idiopathic pulmonary fibrosis (IPF). METHOD...

journal_title：Chest

authors： Oda T,Ogura T,Kitamura H,Hagiwara E,Baba T,Enomoto Y,Iwasawa T,Okudela K,Takemura T,Sakai F,Hasegawa Y

更新日期：2014-11-01 00:00:00

abstract：:We compared the bronchodilator effects and systemic tolerability of 12, 24 and 48 micrograms formoterol DP capsules with 12 micrograms formoterol MDI and placebo in 30 patients with reversible obstructive airway disease. Pulmonary function tests were done and pulse rate and blood pressure were recorded. We observed si...

journal_title：Chest

authors： Maesen FP,Costongs R,Smeets SJ,Zweers PG,Goedhart DM

更新日期：1992-05-01 00:00:00

abstract：:Since first described in 1984, nontraumatic pneumothoraces in patients with AIDS has become more common. When compared with spontaneous pneumothorax in the general population, pneumothoraces in patients with AIDS are often complicated by prolonged air leaks as well as higher recurrence rates. Chemical pleurodesis has ...

journal_title：Chest

authors： Read CA,Reddy VD,O'Mara TE,Richardson MS

更新日期：1994-03-01 00:00:00