Mycobacterium avium complex pulmonary disease presenting as an isolated lingular or middle lobe pattern. The Lady Windermere syndrome.


BACKGROUND:Pulmonary disease due to Mycobacterium avium complex (MAC-PD) radiographically resembles that due to tuberculosis; it preferentially affects elderly white men with predisposing pulmonary disorders (PDPD). METHODS:Twenty-nine patients with MAC-PD were identified from a community-based population, and the medical records and chest roentgenograms (CRs) of six with a previously undescribed pattern of MAC-PD were reviewed. The distinctive clinical and demographic features of these six patients were identified and summarized. RESULTS:All were women who tended to be elderly. None had clinically evident PDPD. The dependent portion of the lingula or its counterpart, the middle lobe, was initially affected. Hilar adenopathy, volume loss, and cavitary disease were uniformly absent. CONCLUSIONS:To account for the distinctive features of this syndrome, we offer the hypothesis that habitual voluntary suppression of cough may have led to the development of nonspecific inflammatory processes in these poorly draining lung regions, upon which MAC-PD engrafted. We offer the term, Lady Windermere's syndrome, to describe this pattern among elderly women and to suggest that their fastidiousness may be its root cause.






Reich JM,Johnson RE




Has Abstract


1992-06-01 00:00:00
















  • Human Epididymis Protein 4: A Novel Serum Inflammatory Biomarker in Cystic Fibrosis.

    abstract:BACKGROUND:Increased expression of the human epididymis protein 4 (HE4) was previously described in lung biopsy samples from patients with cystic fibrosis (CF). It remains unknown, however, whether serum HE4 concentrations are elevated in CF. METHODS:Seventy-seven children with CF from six Hungarian CF centers and 57 ...


    pub_type: 杂志文章


    authors: Nagy B Jr,Nagy B,Fila L,Clarke LA,Gönczy F,Bede O,Nagy D,Újhelyi R,Szabó Á,Anghelyi A,Major M,Bene Z,Fejes Z,Antal-Szalmás P,Bhattoa HP,Balla G,Kappelmayer J,Amaral MD,Macek M Jr,Balogh I

    更新日期:2016-09-01 00:00:00

  • Percutaneous transfemoral coronary arteriography; prevention of morbid complication.

    abstract::During a six-year experience involving 3,089 selective coronary arteriograms (99 percent by the percutaneous transfemoral method), modifications of technique have reduced the incidence of morbid complications. Modifications have involved guidewire technique, systemic heparinization, attention to spontaneous catheter b...


    pub_type: 杂志文章


    authors: Page HL Jr,campbell WB

    更新日期:1975-02-01 00:00:00

  • Quantification of traumatic hemomediastinum using transesophageal echocardiography: impact on patient management.

    abstract:STUDY OBJECTIVES:To determine whether the quantitative evaluation of hemomediastinum using transesophageal echocardiography (TEE) is predictive of the presence of a traumatic disruption of the thoracic aorta (TDA) or its branches in patients who have sustained severe blunt chest trauma. DESIGN:Retrospective study. SE...


    pub_type: 杂志文章


    authors: Vignon P,Rambaud G,François B,Preux PM,Lang RM,Gastinne H

    更新日期:1998-06-01 00:00:00

  • Prediction of successful ventilator weaning using airway occlusion pressure and hypercapnic challenge.

    abstract::We studied eleven patients during 14 attempts at weaning from mechanical ventilation to determine whether central ventilatory drive, measured as airway occlusion pressure 0.1 s after onset of inspiration (P 0.1), during spontaneous breathing before and during a brief hypercapnic challenge, could accurately predict the...


    pub_type: 杂志文章


    authors: Montgomery AB,Holle RH,Neagley SR,Pierson DJ,Schoene RB

    更新日期:1987-04-01 00:00:00

  • Patterns of Use of Adjunctive Therapies in Patients With Early Moderate to Severe ARDS: Insights From the LUNG SAFE Study.

    abstract:BACKGROUND:Adjunctive strategies are an important part of the management of ARDS. However, their application in clinical practice remains inconsistent. RESEARCH QUESTION:We wished to determine the frequency and patterns of use of adjunctive strategies in patients with moderate to severe ARDS (Pao2/Fio2 [P/F ratio] < 1...


    pub_type: 杂志文章


    authors: Duggal A,Rezoagli E,Pham T,McNicholas BA,Fan E,Bellani G,Rubenfeld G,Pesenti AM,Laffey JG,LUNG SAFE Investigators and the ESICM Trials Group.

    更新日期:2020-06-01 00:00:00

  • Nutritional support for individuals with COPD: a meta-analysis.

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    pub_type: 临床试验,杂志文章,meta分析,随机对照试验


    authors: Ferreira IM,Brooks D,Lacasse Y,Goldstein RS

    更新日期:2000-03-01 00:00:00

  • Improved management of acute asthma among pregnant women presenting to the ED.

    abstract:BACKGROUND:A multicenter study in the late 1990s demonstrated suboptimal emergency asthma care for pregnant women in US EDs. After a decade, follow-up data are lacking. We aimed to examine changes in emergency asthma care of pregnant women since the 1990s. METHODS:We combined data from four multicenter observational s...


    pub_type: 杂志文章


    authors: Hasegawa K,Cydulka RK,Sullivan AF,Langdorf MI,Nonas SA,Nowak RM,Wang NE,Camargo CA Jr

    更新日期:2015-02-01 00:00:00

  • Pulmonary vein obstruction following single lung transplantation.

    abstract::Angiographic documentation after single lung transplant showed pulmonary venous obstruction due to compression by the omental pedicle. Retransplantation is described, and this complication is examined. ...


    pub_type: 杂志文章


    authors: Malden ES,Kaiser LR,Gutierrez FR

    更新日期:1992-08-01 00:00:00

  • Negative pressure pulmonary edema following bronchospasm.

    abstract::Negative pressure pulmonary edema (NPPE) is an important cause of noncardiogenic pulmonary edema but is rarely reported in the setting of bronchospasm. A 43-year-old woman with severe reactive airway disease suffered an episode of severe bronchospasm after endotracheal extubation following an otherwise uneventful gene...


    pub_type: 杂志文章


    authors: Krodel DJ,Bittner EA,Abdulnour RE,Brown RH,Eikermann M

    更新日期:2011-11-01 00:00:00

  • Concomitant assessment of depth of sedation by changes in bispectral index and changes in autonomic variables (heart rate and/or BP) in pediatric critically ill patients receiving neuromuscular blockade.

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    pub_type: 杂志文章


    authors: Trope RM,Silver PC,Sagy M

    更新日期:2005-07-01 00:00:00

  • The snoring spectrum: acoustic assessment of snoring sound intensity in 1,139 individuals undergoing polysomnography.

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    pub_type: 杂志文章


    authors: Wilson K,Stoohs RA,Mulrooney TF,Johnson LJ,Guilleminault C,Huang Z

    更新日期:1999-03-01 00:00:00

  • A practical algorithmic approach to the diagnosis and management of solitary pulmonary nodules: part 1: radiologic characteristics and imaging modalities.

    abstract::The solitary pulmonary nodule (SPN) is frequently encountered on chest imaging and poses an important diagnostic challenge to clinicians. The differential diagnosis is broad, ranging from benign granulomata and infectious processes to malignancy. Important concepts in the evaluation of SPNs include the definition, mor...


    pub_type: 杂志文章,评审


    authors: Patel VK,Naik SK,Naidich DP,Travis WD,Weingarten JA,Lazzaro R,Gutterman DD,Wentowski C,Grosu HB,Raoof S

    更新日期:2013-03-01 00:00:00

  • Safety of long-term treatment with HFA albuterol.

    abstract:BACKGROUND:Chlorofluorocarbons (CFCs) used as propellants in metered-dose inhalers deplete stratospheric ozone, which results in serious public health concerns. Albuterol has been reformulated in the non-ozone-depleting propellant, hydrofluoroalkane-134a (HFA albuterol). OBJECTIVES:The primary objective was to compare...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Ramsdell JW,Klinger NM,Ekholm BP,Colice GL

    更新日期:1999-04-01 00:00:00

  • Measurement of dynamic hyperinflation after a 6-minute walk test in patients with COPD.

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    pub_type: 杂志文章


    authors: Callens E,Graba S,Gillet-Juvin K,Essalhi M,Bidaud-Chevalier B,Peiffer C,Mahut B,Delclaux C

    更新日期:2009-12-01 00:00:00

  • The role of computer games in measuring spirometry in healthy and "asthmatic" preschool children.

    abstract:STUDY OBJECTIVES:To explore the role of respiratory interactive computer games in teaching spirometry to preschool children, and to examine whether the spirometry data achieved are compatible with acceptable criteria for adults and with published data for healthy preschool children, and whether spirometry at this age c...


    pub_type: 杂志文章


    authors: Vilozni D,Barak A,Efrati O,Augarten A,Springer C,Yahav Y,Bentur L

    更新日期:2005-09-01 00:00:00

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    pub_type: 杂志文章


    authors: Priou P,Hamel JF,Person C,Meslier N,Racineux JL,Urban T,Gagnadoux F

    更新日期:2010-07-01 00:00:00

  • Treatment of sarcoidosis-associated pulmonary hypertension. A two-center experience.

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    pub_type: 杂志文章,多中心研究


    authors: Barnett CF,Bonura EJ,Nathan SD,Ahmad S,Shlobin OA,Osei K,Zaiman AL,Hassoun PM,Moller DR,Barnett SD,Girgis RE

    更新日期:2009-06-01 00:00:00

  • Effects of hypercapnia on hemodynamic, inotropic, lusitropic, and electrophysiologic indices in humans.

    abstract:STUDY OBJECTIVE:The inotropic, lusitropic, and electrophysiologic effects of acute hypercapnia in humans are not known. Although the effects of hypercapnia on the systemic circulation have been well documented, there is still some debate as to whether hypercapnia causes true pulmonary vasoconstriction in vivo. We have ...


    pub_type: 杂志文章


    authors: Kiely DG,Cargill RI,Lipworth BJ

    更新日期:1996-05-01 00:00:00

  • Coronary artery bypass surgery in patients less than 40 years of age.

    abstract::Coronary bypass patients less than 40 years of age were identified and compared with a control group previously studied at our hospital. In patients less than 40 years, the average age was 35 years. Men comprised 90.1 percent of group 1, and 83.4 percent of group 2. Operative mortality was 2.89 percent for group 1 and...


    pub_type: 杂志文章


    authors: Kelly ME,DeLaria GA,Najafi H

    更新日期:1988-12-01 00:00:00

  • Right upper lobe pulmonary edema caused by acute mitral regurgitation. Diagnosis by transesophageal echocardiography.

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    pub_type: 杂志文章


    authors: Roach JM,Stajduhar KC,Torrington KG

    更新日期:1993-04-01 00:00:00

  • Long-term outcomes for elderly survivors of prolonged ventilator assistance.

    abstract::Care of ventilator-dependent patients requires considerable resources, yet the long-term outcomes of this type of care have rarely been described. We retrospectively investigated the posthospital course of elderly patients who survived an episode of prolonged ventilator dependency to describe survival rates, subsequen...


    pub_type: 杂志文章


    authors: Elpern EH,Larson R,Douglass P,Rosen RL,Bone RC

    更新日期:1989-11-01 00:00:00

  • OSA and pulmonary hypertension: time for a new look.

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    pub_type: 杂志文章,评审


    authors: Ismail K,Roberts K,Manning P,Manley C,Hill NS

    更新日期:2015-03-01 00:00:00

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    abstract::Marked airway obstruction and interference with gas exchange was encountered following institution of general anesthesia for resection of a cystic subcarinal mass. Intraoperative bronchoscopy revealed marked airway compression. The cyst was decompressed using a transbronchial needle through a fiberbronchoscope. This a...


    pub_type: 杂志文章


    authors: McDougall JC,Fromme GA

    更新日期:1990-06-01 00:00:00

  • Emergency Medical Treatment and Labor Act: what every physician should know about the federal antidumping law.

    abstract::Since 1986, the Emergency Medical Treatment and Labor Act (EMTALA) has imposed an obligation on hospitals and physicians to evaluate and stabilize patients who present to a hospital ED seeking care. Available sanctions for noncompliance include fines, damages awarded in civil litigation, and exclusion from Medicare. E...


    pub_type: 杂志文章,评审


    authors: Hyman DA,Studdert DM

    更新日期:2015-06-01 00:00:00

  • Detection of unstable angina by 99m technetium pyrophosphate myocardial scintigraphy.

    abstract::99mTechnetium stannous pyrophosphate has been shown to accumulate in acutely infarcted myocardium. To determine if the isotope is also taken up by severely ischemic, but not necrotic myocardium, we performed myocardial scintigraphic studies in 17 patients with chest pains. Seven of the patients satisfied conventional ...


    pub_type: 杂志文章


    authors: Abdulla AM,Canedo MI,Cortez BC,McGinnis KD,Wilhelm SK

    更新日期:1976-02-01 00:00:00

  • Pleural effusion in Churg-Strauss syndrome.

    abstract::A 33-year-old man with a two-year history of asthma and sinusitis presented with wheezing, pleuritis, bilateral pleural effusions, and patchy basilar infiltrates on chest roentgenogram. Laboratory studies revealed peripheral blood eosinophilia, and pulmonary function studies showed an obstructive pattern which was bro...


    pub_type: 杂志文章


    authors: Erzurum SC,Underwood GA,Hamilos DL,Waldron JA

    更新日期:1989-06-01 00:00:00

  • Outcome prediction in chest injury by a mathematical search and display program.

    abstract:OBJECTIVE:This study applies a stochastic or probability search and display model to prospectively predict outcome and to evaluate therapeutic effects in a consecutively monitored series of 396 patients with severe thoracic and thoracoabdominal injuries. STUDY DESIGN:Prospective observational study of outcome predicti...


    pub_type: 杂志文章


    authors: Shoemaker WC,Bayard DS,Wo CC,Chan LS,Chien LC,Lu K,Jelliffe RW

    更新日期:2005-10-01 00:00:00

  • An 84-Year-Old Man With Progressive Dyspnea and an Abnormal Chest CT Scan.

    abstract:CASE PRESENTATION:An 84-year-old man without a history of smoking presented with progressive dyspnea of 6 months' duration accompanied by fatigue and unintentional weight loss. He denied fever, chills, chest pain, hemoptysis, rash, joint pains, or muscle aches. He had multiple hospitalizations for similar presentations...


    pub_type: 杂志文章


    authors: Fakih HAM,Samra Y,Ataya A,Prasad A,Papierniak E,Wakefield D,Urbine D

    更新日期:2017-08-01 00:00:00

  • Elevated levels of soluble interleukin-2 receptors in tuberculous pleural effusions.

    abstract::The levels of soluble IL-2R were measured in pleural fluid from patients with tuberculosis pleurisy. There were significantly elevated soluble IL-2R values in tuberculous pleural fluid as compared with pleural fluid of nontuberculous etiology including malignant, bacterial and transudative pleural effusions. In patien...


    pub_type: 杂志文章


    authors: Ito M,Kojiro N,Shirasaka T,Moriwaki Y,Tachibana I,Kokubu T

    更新日期:1990-05-01 00:00:00

  • Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial.

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    pub_type: 杂志文章,随机对照试验


    authors: Anderson WJ,Short PM,Williamson PA,Lipworth BJ

    更新日期:2012-12-01 00:00:00