Abstract:
BACKGROUND:Pulmonary disease due to Mycobacterium avium complex (MAC-PD) radiographically resembles that due to tuberculosis; it preferentially affects elderly white men with predisposing pulmonary disorders (PDPD). METHODS:Twenty-nine patients with MAC-PD were identified from a community-based population, and the medical records and chest roentgenograms (CRs) of six with a previously undescribed pattern of MAC-PD were reviewed. The distinctive clinical and demographic features of these six patients were identified and summarized. RESULTS:All were women who tended to be elderly. None had clinically evident PDPD. The dependent portion of the lingula or its counterpart, the middle lobe, was initially affected. Hilar adenopathy, volume loss, and cavitary disease were uniformly absent. CONCLUSIONS:To account for the distinctive features of this syndrome, we offer the hypothesis that habitual voluntary suppression of cough may have led to the development of nonspecific inflammatory processes in these poorly draining lung regions, upon which MAC-PD engrafted. We offer the term, Lady Windermere's syndrome, to describe this pattern among elderly women and to suggest that their fastidiousness may be its root cause.
journal_name
Chestjournal_title
Chestauthors
Reich JM,Johnson REdoi
10.1378/chest.101.6.1605subject
Has Abstractpub_date
1992-06-01 00:00:00pages
1605-9issue
6eissn
0012-3692issn
1931-3543pii
S0012-3692(16)38408-2journal_volume
101pub_type
杂志文章相关文献
CHEST文献大全abstract:BACKGROUND:It has been reported, but not proven, that perioperative blood transfusions have a detrimental effect on the survival of patients undergoing surgery for lung cancer. STUDY DESIGN:and methods: A prospective study was carried out on the patients undergoing lobectomy for stage I lung cancer at our department f...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.124.1.102
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:Postoperative pulmonary hypertension (POPH) substantially increases mortality after repair of congenital heart diseases. Inhaled nitric oxide (NO) has been reported as an effective and specific means of controlling POPH crisis. No randomized, placebo-controlled study has addressed the ability of NO administra...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.5.3537
更新日期:2005-11-01 00:00:00
abstract::Two cases are presented in which a Dormia ureteral stone dislodger with straight filiform tip was used to retrieve broken central venous pressure catheters from the right side of the heart and vena cavae. It should be emphasized that this particular model is more easily passed into the vascular system and more easily ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.69.3.435
更新日期:1976-03-01 00:00:00
abstract:STUDY OBJECTIVE:To analyze the cough response to three airway challenges in order to clarify whether the recording of the provoked coughs would be beneficial in the management of asthma. DESIGN:A prospective study. SETTING:University hospital. PARTICIPANTS:Fifteen healthy subjects, 16 steroid-naïve subjects with ast...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1378/chest.128.5.3329
更新日期:2005-11-01 00:00:00
abstract::Of all patients presenting at our level 1 trauma center with multiorgan system injuries, 33 have been identified with acute lesions of the thoracic aorta. Mean severity injury score was 24 +/- 3. Four patients underwent resuscitative thoracotomy upon arrival in the emergency department. One survived and fully recovere...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.2.331
更新日期:1992-02-01 00:00:00
abstract:STUDY OBJECTIVES:To analyze the outcome of acute respiratory failure (ARF) in patients with idiopathic pulmonary fibrosis (IPF), and to evaluate the benefits of invasive and noninvasive mechanical ventilation (MV). DESIGN:Retrospective study. SETTING:University hospital. PATIENTS:Fifteen consecutive patients with IP...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.1.209
更新日期:2001-07-01 00:00:00
abstract::Prior antibiotic therapy, size of the infiltrate, and the person who performed the technique were the three factors that we studied to assess their influence on the effectiveness of transthoracic needle aspiration (TNA). Ninety-one patients with a diagnosis of severe bacterial pneumonia, who underwent TNA, have been i...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.107.1.96
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy, permanence, and safety of thoracoscopic talc poudrage (TTP) for pleurodesis in malignant effusions. DESIGN:Retrospective. PARTICIPANTS:Patients with lifetime follow-up who received TTP in two related centers in Marseilles, France. RESULTS:Three hundred sixty patients were included i...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.110.6.1387
更新日期:1996-12-01 00:00:00
abstract::Between December 1985 and August 1988, there were 115 patients at 13 centers who were entered on a randomized comparison of tetracycline and bleomycin for treatment of malignant pleural effusions. Fifteen patients were not treated, primarily due to rapid progression of systemic cancer. Fifteen patients entered on a hi...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1378/chest.100.6.1528
更新日期:1991-12-01 00:00:00
abstract::The issue of tobacco industry responsibility for population health problems and compensation for their treatment has been growing since the 1960s. In 1999, the state attorneys general collectively launched the largest class action lawsuit in US history and sued the tobacco industry to recover the costs of caring for s...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.09-0982
更新日期:2010-03-01 00:00:00
abstract:STUDY OBJECTIVE:To determine whether patients with congestive heart failure who develop Cheyne-Stokes respiration (CSR) during sleep experience excessive daytime sleepiness. This was addressed by comparing sleep quality and daytime sleepiness in three groups: patients with CHF and CSR during sleep (CSR group), patients...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.107.4.952
更新日期:1995-04-01 00:00:00
abstract:STUDY OBJECTIVES:To evaluate the safety and efficacy of sitaxsentan, an endothelin-A receptor antagonist, in a 12-week, open-label trial of patients with pulmonary arterial hypertension (PAH). PATIENTS:Six children and 14 adults with New York Heart Association (NYHA) functional class II, III, or IV primary pulmonary h...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1378/chest.121.6.1860
更新日期:2002-06-01 00:00:00
abstract::A 60-pack-year smoker presented with cough, dyspnea and orthopnea of three months' duration. Spirometry revealed severe reduction in maximal expiratory flow; CT of the chest and bronchoscopy demonstrated expiratory collapse of a mid-tracheal segment, and a presumptive diagnosis of tracheomalacia was made. A right late...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.4.939
更新日期:1990-04-01 00:00:00
abstract::Antiphospholipid syndrome is an autoimmune disorder characterized by a hypercoagulable state, leading to arterial and venous thrombosis. We present a 23-year-old patient, suspected of having Budd-Chiari syndrome due to antiphospholipid syndrome, who developed severe and progressive hypoxemia, requiring prolonged mecha...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.13-2879
更新日期:2014-11-01 00:00:00
abstract::Fungal endocarditis is a rare complication of permanent pacemaker implantation. In all reports we have identified, this infection has been fatal, diagnosed postmortem. We present a patient in whom early echocardiographic diagnosis resulted in curative surgical and antimicrobial therapy. Fungal endocarditis is an unusu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.1.283
更新日期:1993-01-01 00:00:00
abstract::This is the first reported case of discrete fibrous subaortic stenosis in tetralogy of Fallot. Transaortic excision of the subaortic membrane was readily accomplished. To detect this and other forms of left ventricular outflow-tract obstruction in tetralogy of Fallot before surgery, routine selective left ventriculogr...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.69.4.543
更新日期:1976-04-01 00:00:00
abstract::Significant concentrations of asbestos fibers have been found in samples of laryngeal tissue from two patients with past exposure to asbestos and associated asbestosis. In one case, there was a polyp on a vocal cord and in the other one a laryngeal carcinoma. These findings could provide an indication of a local carci...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.6.697
更新日期:1979-12-01 00:00:00
abstract::The study objective was to assess the widespread applicability of ST/HR slope for the modified Bruce exercise test using a computerized electrocardiogram (ECG); compare the usefulness of the ST/HR slope with standard ECG criteria in detection of coronary artery disease (CAD) and identification of three-vessel or left ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.94.4.737
更新日期:1988-10-01 00:00:00
abstract::Prior to 1978, the conventional treatment of pneumothorax generally consisted of conservative therapies such as rest, needle puncture, or thoracic cavity drainage; however, when conservative therapies were ineffective or relapse occurred therapeutic approach, 34 percent (11/32) of our patients required a thoracotomy. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.100.4.953
更新日期:1991-10-01 00:00:00
abstract::Liposarcoma is rare in children and rarely occurs in the posterior mediastinum in any age group. A massive intrathoracic tumor in a 17-year-old young man was a diagnostic dilemma; preoperative radiographic evaluation and biopsy led us to believe it was a teratoma. At operation, a poorly differentiated myxoid liposarco...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.106.4.1288
更新日期:1994-10-01 00:00:00
abstract::Cocaine use is associated with adverse events in nearly every organ system. Cardiovascular complications include hemorrhagic and ischemic stroke, aortic dissection, cardiomyopathy, accelerated coronary artery disease, myocardial infarction, and sudden cardiac death. Syncope may be the presenting symptom in these condi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.1.275
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The Parent Cough-Specific Quality-of-Life questionnaire (PC-QOL) has relevance and clinical utility as a cough-specific QOL measure for pediatric use. Its validity has been demonstrated. This study sought to determine the minimally important difference (MID) for the PC-QOL completed by parents of young child...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-1476
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Patients with common variable immunodeficiency (CVID) suffer from respiratory infections leading over time to permanent lung damage. Increased radiosensitivity has been described, and clinicians should consider a risk-benefit assessment when ordering a CT scan, in that the exact level of "safe" radiation exp...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-3147
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:The airways in patients with cystic fibrosis (CF) are characterized by the accumulation of tenacious, dehydrated mucus that is a precursor for chronic infection, inflammation, and tissue destruction. The clearance of mucus is an integral component of daily therapy. Inhaled mannitol is an osmotic agent that i...
journal_title:Chest
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1378/chest.07-2294
更新日期:2008-06-01 00:00:00
abstract::Histochemical quantification of goblet cells and measurements of the epithelial thickness were made in the trachea of male and female rats exposed to fresh whole tobacco smoke for 30 consecutive days. Exposure to tobacco smoke resulted in an increase in the total goblet cell count in both sexes, with the female rats d...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.73.4.515
更新日期:1978-04-01 00:00:00
abstract:STUDY OBJECTIVES:To determine whether, in patients with bilateral pleural effusions, the main cellular and biochemical features of the pleural fluid on the right side differ from or correlate with those on the left side. We examined lactate dehydrogenase (LDH), glucose, and total protein (TP) levels, RBC count, nucleat...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.124.1.167
更新日期:2003-07-01 00:00:00
abstract::Measurement of lung volumes is an integral part of complete pulmonary function testing. Some lung volumes can be measured during spirometry; however, measurement of the residual volume (RV), functional residual capacity (FRC), and total lung capacity (TLC) requires special techniques. FRC is typically measured by one ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.11-2964
更新日期:2012-08-01 00:00:00
abstract::A 20-year-old woman developed severe shortness of breath 4 h after a cesarean section. Chest roentgenogram showed a pleural effusion and tension pneumothorax; insertion of a chest tube drained liquid stool. At surgery she was found to have a left diaphragmatic defect with herniation, strangulation, and perforation of ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.3.950
更新日期:1993-03-01 00:00:00
abstract::A 32-year-old man who presented with symptoms suggesting empyema was found at thoracotomy to have infarction of an extralobar pulmonary sequestration. He was completely relieved by excision of the sequestration after securing the systemic vascular pedicle which had undergone torsion. Recognition of the anomalous blood...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.68.1.98
更新日期:1975-07-01 00:00:00
abstract::The resurgence of tuberculosis (TB) in the early 1990s, including multidrug-resistant strains, led health officials to recommend the use of involuntary detention for persistently nonadherent patients. Using a series of recently published articles on the subject, this paper offers some opinions on how detention program...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.115.1.236
更新日期:1999-01-01 00:00:00