Differential response in the male and female tracheal epithelium following exposure to tobacco smoke.

abstract：BACKGROUND:Limited data are available on the impact of time to ICU admission and outcomes for patients with severe community acquired pneumonia (CAP). Our objective was to examine the association of time to ICU admission and 30-day mortality in patients with severe CAP. METHODS:A retrospective cohort study of 161 ICU ...

journal_title：Chest

authors： Restrepo MI,Mortensen EM,Rello J,Brody J,Anzueto A

更新日期：2010-03-01 00:00:00

abstract：:The most frequent radiographic presentation of (PCP) is bilateral interstitial or alveolar infiltrates. Atypical features include lobar distribution, pleural effusions, hilar adenopathy, cyst formation and spontaneous pneumothorax. A diffuse miliary pattern has not been described previously for PCP. A 30-year-old male...

journal_title：Chest

authors： Wasser LS,Brown E,Talavera W

更新日期：1989-09-01 00:00:00

abstract：:We studied the reproducibility of tests of RM performance in normal elderly subjects and compared their performance with that of patients with COPD. The RM strength was measured as MIP and MEP. The RM endurance was measured using a two-minute incremental threshold loading test. The max load, the average Ppk as %MIP at...

journal_title：Chest

authors： Morrison NJ,Richardson J,Dunn L,Pardy RL

更新日期：1989-01-01 00:00:00

abstract：RATIONALE:Airway hyperresponsiveness to adenosine monophosphate (AMP) has been validated as a surrogate marker for airway inflammation. We wished to know whether an abbreviated challenge at the final threshold dose would produce the same fall in FEV1 as a full, conventional dose-response challenge. METHODS:Seventeen p...

journal_title：Chest

authors： Fardon TC,Hodge MR,Lipworth BJ

更新日期：2005-06-01 00:00:00

abstract：:OSA is a common yet underdiagnosed disorder encountered in everyday practice. The disease is a unique physiologic stressor that contributes to the development or progression of many other disorders, particularly cardiovascular conditions. The pulmonary circulation is specifically affected by the intermittent hypoxic a...

journal_title：Chest

authors： Ismail K,Roberts K,Manning P,Manley C,Hill NS

更新日期：2015-03-01 00:00:00

abstract：:Although the relationship between blood pressure and cardiac performance has been widely recognized, there are few published clinical observations concerning the effect of blood pressure control on cardiac function. We evaluated the effect of prazosin, an antihypertensive agent which also improves hemodynamic measurem...

journal_title：Chest

authors： Massie BM,Chan S

更新日期：1981-12-01 00:00:00

abstract：:A saccular aneurysm arising from the descending thoracic aorta was identified ultrasonically in a 60-year-old man with a subsequent pathologic diagnosis of a Listeria monocytogenes mycotic aneurysm. A cross-sectional scanning technique, which permitted visualization of the descending thoracic aorta in long axis, demon...

journal_title：Chest

authors： Come PC,Sacks B,Vine H,McArdle C,Koretsky S,Weintraub R

更新日期：1981-04-01 00:00:00

abstract：STUDY OBJECTIVES:To describe the health-related quality of life (HRQL) and mental health of persons with sarcoidosis, as well as to assess physician-patient agreement about the presence of sarcoidosis symptoms. DESIGN AND SETTING:Cross-sectional study at three university medical center outpatient pulmonary clinics. P...

journal_title：Chest

authors： Cox CE,Donohue JF,Brown CD,Kataria YP,Judson MA

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Male sex is an independent predictor of worse survival in pulmonary arterial hypertension (PAH). This finding might be explained by more severe pulmonary vascular disease, worse right ventricular (RV) function, or different response to therapy. The aim of this study was to investigate the underlying cause of...

journal_title：Chest

authors： Jacobs W,van de Veerdonk MC,Trip P,de Man F,Heymans MW,Marcus JT,Kawut SM,Bogaard HJ,Boonstra A,Vonk Noordegraaf A

更新日期：2014-06-01 00:00:00

abstract：:Esophageal malposition is a potentially disastrous complication of attempted airway intubation. We report an unusual case in which a promptly recognized esophageal intubation aided detection of a perforated gastric ulcer. After the endotracheal tube was repositioned and the ulcer was surgically repaired, our patient h...

journal_title：Chest

authors： Dunham D,Schmidt GA

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Hospital readmissions for acute exacerbations of COPD (AECOPDs) pose burdens to the health-care system and patients. A current gap in knowledge is whether a predischarge screening and educational tool administered to patients with COPD reduces readmissions and ED visits. METHODS:A single-center, randomized ...

journal_title：Chest

authors： Jennings JH,Thavarajah K,Mendez MP,Eichenhorn M,Kvale P,Yessayan L

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to assess the usefulness of a specific inspiratory muscle training in Duchenne muscular dystrophy (DMD). PATIENTS AND METHODS:Fifteen patients with DMD started 6 months of training the inspiratory muscles and 15 patients served as a control group. Pulmonary and inspiratory muscle func...

journal_title：Chest

authors： Wanke T,Toifl K,Merkle M,Formanek D,Lahrmann H,Zwick H

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:Analysis of laryngotracheoscopic findings of the upper airway tract following percutaneous tracheostomy using the technique according to Griggs. DESIGN:Retrospective cohort study PATIENTS:Nineteen of 32 long-term surviving patients (mean follow-up duration, 17 months; range, 11 to 23 months) underwent a mod...

journal_title：Chest

authors： Dollner R,Verch M,Schweiger P,Deluigi C,Graf B,Wallner F

更新日期：2002-07-01 00:00:00

abstract：:Plug closure of patent ductus arteriosus without thoracotomy is reliable and can be a good alternative to surgical closure for selected patients. We report our experiences with plug closure in 87 consecutive patients (age range, 3 to 38 years). Closure was successful in 83 patients (95 percent). There has been no mort...

journal_title：Chest

authors： Kitamura S,Sato K,Naito Y,Shimizu Y,Fujino M

更新日期：1976-11-01 00:00:00

abstract：:Cardiorespiratory values were measured in ten patients with severe respiratory failure on volume controlled and pressure controlled ventilation. Tidal volume, respirator rate, PEEP, auto-PEEP, inspiratory:expiratory ratio (1:2) and FIo2 were maintained at the same value for both ventilatory modalities. Changing from V...

journal_title：Chest

authors： Abraham E,Yoshihara G

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Conventional tests are not always helpful in making a diagnosis of tuberculous pleurisy. Many studies have investigated the usefulness of interferon (IFN)-gamma measurements in pleural fluid for the early diagnosis of tuberculous pleurisy. We conducted a metaanalysis to determine the accuracy of IFN-gamma me...

journal_title：Chest

authors： Jiang J,Shi HZ,Liang QL,Qin SM,Qin XJ

更新日期：2007-04-01 00:00:00

abstract：:A man with primary lung cancer developed respiratory failure due to lymphangitis carcinomatosis that was diagnosed by transbronchial lung biopsy specimen. After combination chemotherapy with high-dose etoposide and cisplatin (CDDP), he was able to cease oxygen therapy and showed improvement of his lymphangitis carcino...

journal_title：Chest

authors： Fujita J,Yamagishi Y,Kubo A,Takigawa K,Yamaji Y,Takahara J

更新日期：1993-03-01 00:00:00

abstract：:Two patients with schistosomal cor pulmonale and central cyanosis were studied by contrast-enhanced echocardiography, using indocyanine green injection. Intrapulmonary shunts were detected by this method. To our knowledge, this is the first report that proves the presence of intrapulmonary shunts in schistosomal cor p...

journal_title：Chest

authors： Rafla SM,Sourour S

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Therapist-implemented protocols have been used to extubate or wean patients in the ICU setting. Barlow Respiratory Hospital (BRH) functions as a center for weaning patients from prolonged mechanical ventilation (PMV) in the post-ICU setting of a long-term acute-care (LTAC) facility. A therapist-implemented p...

journal_title：Chest

authors： Scheinhorn DJ,Chao DC,Stearn-Hassenpflug M,Wallace WA

更新日期：2001-01-01 00:00:00

abstract：:The previously unreported association of chronic persistent cough due to a duplication esophageal cyst is presented. The presence of a long history of atopy, bronchitis, and asthma resulted in a delay in diagnosis. When vigorous bronchodilator therapy was unsuccessful, close observation of the patient and review of he...

journal_title：Chest

authors： Bowton DL,Katz PO

更新日期：1984-07-01 00:00:00

abstract：:Native valve endocarditis normally presents with fever and only later in its course demonstrates dysfunction of the affected valve. We describe a case of endocarditis due to Neisseria subflava, a Gram-negative diplococcal saprophyte of the oral cavity, which was unsuspected clinically and found unexpectedly during a m...

journal_title：Chest

authors： Amsel BJ,Moulijn AC

更新日期：1996-01-01 00:00:00

abstract：:A 54-year-old Japanese man demonstrated a sultamicillin-induced hilar and mediastinal lymphadenopathy with hypersensitivity pneumonitis. A positive lymphocyte stimulation test for sultamicillin and a decreased CD4/CD8 ratio of lymphocytes in BAL fluid suggested that an alteration in cell-mediated mechanisms was respon...

journal_title：Chest

authors： Yonemaru M,Mizuguchi Y,Kasuga I,Utsumi K,Ichinose Y,Toyama K

更新日期：1992-12-01 00:00:00

abstract：:Bronchoscopy is essential to the practice of pulmonary medicine. It is an important diagnostic and therapeutic tool for many disease processes. Bronchoscopy can be performed in a variety of clinical settings, from the bedside to an operating room. Although bronchoscopy has been practiced for more than a century, conse...

journal_title：Chest

authors： Mehta AC,Avasarala SK,Jain P,Deshwal H,Gildea TR

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Acquired somatic mutations induced by oxidative stress may contribute to the molecular pathogenesis of chronic inflammatory airway diseases. The objective of this study was to assess the intensity of oxidative DNA damage and the presence of microsatellite DNA instability (MSI), a marker of acquired somatic m...

journal_title：Chest

authors： Tzortzaki EG,Dimakou K,Neofytou E,Tsikritsaki K,Samara K,Avgousti M,Amargianitakis V,Gousiou A,Menikou S,Siafakas NM

更新日期：2012-05-01 00:00:00

abstract：:Our current understanding of the pathogenesis of sepsis suggests that bacteria as well as bacterial-derived products activate an uncontrolled network of host-derived mediators such as proinflammatory cytokines (ie, tumor necrosis factor [TNF] and interleukin [IL]-1beta), which can ultimately lead to cardiovascular col...

journal_title：Chest

authors： Knuefermann P,Nemoto S,Baumgarten G,Misra A,Sivasubramanian N,Carabello BA,Vallejo JG

更新日期：2002-04-01 00:00:00

abstract：:The occasional use of over-the-counter (OTC) epinephrine inhalers appears to be safe and effective when used according to labeled instruction by individuals with mild, intermittent asthma. However, gross misuse of these products can cause severe adverse reactions, including death. Limited survey data suggest that appr...

journal_title：Chest

authors： Dickinson BD,Altman RD,Deitchman SD,Champion HC

更新日期：2000-08-01 00:00:00

abstract：:Paclitaxel, the first of the taxanes, has exhibited unique and encouraging single-agent activity in the treatment of non-small cell lung cancer (NSCLC). Yet, with single-agent response rates approaching 25%, it was logical to examine the impact of paclitaxel in combination chemotherapy regimens. In trials evaluating t...

journal_title：Chest

authors： Belani CP

更新日期：2000-04-01 00:00:00

abstract：STUDY OBJECTIVE:To investigate the efficacy and safety profiles of corticosteroid therapy in severe acute respiratory syndrome (SARS) patients. DESIGN:Four hundred one of 1,278 SARS cases treated in Guangzhou China between December 2002 and June 2003 fulfilled the diagnostic criteria issued by the World Health Organiz...

journal_title：Chest

authors： Chen RC,Tang XP,Tan SY,Liang BL,Wan ZY,Fang JQ,Zhong N

更新日期：2006-06-01 00:00:00

abstract：:The significance of dynamic changes of the QS wave magnitude, as demonstrated in the precordial leads, within the natural evolution of acute anterior wall myocardial infarction (AAMI) was assessed in 25 patients within two weeks of their admission to the intensive cardiac care unit. Two sets of tests, including 12-lea...

journal_title：Chest

authors： Klainman E,Sclarovsky S,Zafrir N,Lewin RF,Farbstein H,Agmon J

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a rare disease with a predilection for young women that is associated with right ventricular failure and premature death. PAH can complicate pregnancy with hemodynamic instability or sudden death during parturition and postpartum. Our aim was to examine the impact of ...

journal_title：Chest

authors： Duarte AG,Thomas S,Safdar Z,Torres F,Pacheco LD,Feldman J,deBoisblanc B

更新日期：2013-05-01 00:00:00