Predischarge bundle for patients with acute exacerbations of COPD to reduce readmissions and ED visits: a randomized controlled trial.

abstract：BACKGROUND:COPD is associated with significant morbidity primarily driven by acute exacerbations. Relative pulmonary artery (PA) enlargement, defined as a PA to ascending aorta (A) diameter ratio greater than one (PA:A>1) identifies patients at increased risk for exacerbations. However, little is known about the correl...

journal_title：Chest

authors： Iyer AS,Wells JM,Vishin S,Bhatt SP,Wille KM,Dransfield MT

更新日期：2014-04-01 00:00:00

abstract：:Our understanding of asthma epidemiology is growing increasingly complex. Asthma outcomes are clearly socially patterned, with asthma ranking as a leading cause of health disparities among minority and low socioeconomic groups. Yet, the increasing prevalence and marked disparities in asthma remain largely unexplained ...

journal_title：Chest

authors： Wright RJ,Subramanian SV

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...

journal_title：Chest

authors： Faust HE,Reilly JP,Anderson BJ,Ittner CAG,Forker CM,Zhang P,Weaver BA,Holena DN,Lanken PN,Christie JD,Meyer NJ,Mangalmurti NS,Shashaty MGS

更新日期：2020-01-01 00:00:00

abstract：:Each of four examiners performed standardized physical examinations on a group of patients who had just undergone tests of ventilatory function. The intensity of breath sounds heard with deep inspiration was graded on a rating scale of 0 to 4; the grades in six areas of the chest were added to give a total score, with...

journal_title：Chest

authors： Pardee NE,Martin CJ,Morgan EH

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) remains a public health threat with significant annual impacts on morbidity and mortality. However, few studies have examined the impact of active and latent TB infection (LTBI) on health-related quality of life (HRQL). METHODS:Patients with recently diagnosed active TB or LTBI patients we...

journal_title：Chest

authors： Marra CA,Marra F,Colley L,Moadebi S,Elwood RK,Fitzgerald JM

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Congenital airway malacia is one of the few causes of irreversible airways obstruction in children, but the incidence in the general population is unknown. Severe airway malacia or malacia associated with specific syndromes is usually recognized and diagnosed early in infancy, but information about clinical f...

journal_title：Chest

authors： Boogaard R,Huijsmans SH,Pijnenburg MW,Tiddens HA,de Jongste JC,Merkus PJ

更新日期：2005-11-01 00:00:00

abstract：:A total of 161 patients with chronic obstructive pulmonary disease (COPD) plus 100 control subjects (identified during a study of heart disease in 6,860 Japanese-American men aged 52 to 75 years who were residing in Hawaii) were analyzed for phenotype in search of the antitrypsin gene Z, which has been shown to be ass...

journal_title：Chest

authors： Roberts A,Kagan A,Rhoads GG,Pierce JA,Bruce RM

更新日期：1977-10-01 00:00:00

abstract：:Endobronchial ultrasonography (EBUS) has become an invaluable tool in the diagnosis of patients with a variety of thoracic abnormalities. The majority of EBUS procedures are used to diagnose and stage mediastinal and hilar abnormalities, as well as peripheral pulmonary targets, with a probe-based technology. Nearly 1,...

journal_title：Chest

authors： Gildea TR,Nicolacakis K

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Pulmonary arterial hypertension (PAH) is the most common cause of scleroderma-related deaths. New medications for PAH patients make it necessary to identify patients with high risk factors for PAH. This study looks at the use of an exercise echocardiogram in identifying patients who may have PAH and may be...

journal_title：Chest

authors： Steen V,Chou M,Shanmugam V,Mathias M,Kuru T,Morrissey R

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:To compare the systemic bioavailability (assessed by cortisol suppression) of high-dose budesonide when given by four inhaler devices and orally. Also studied are the relative systemic potencies of three inhaled steroids (budesonide, fluticasone propionate, and beclomethasone dipropionate) when given by mete...

journal_title：Chest

authors： Wales D,Makker H,Kane J,McDowell P,O'Driscoll BR

更新日期：1999-05-01 00:00:00

abstract：:Bronchial thermoplasty (BT) involves the application of radiofrequency energy to visible proximal airways to selectively ablate airway smooth muscle. BT is the first nonpharmacologic interventional therapy approved by the US Food and Drug Administration (FDA) for severe asthma. This approval was based on the results o...

journal_title：Chest

authors： Iyer VN,Lim KG

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Angiogenesis is a prerequisite for airway remodeling in bronchial asthma. Several factors may play important roles in inflammation and angiogenesis through effects on inflammatory cell infiltration or neovascularization. OBJECTIVES:(1) To determine the levels of vascular endothelial growth factor (VEGF) and...

journal_title：Chest

authors： Abdel-Rahman AM,el-Sahrigy SA,Bakr SI

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Rhinovirus (RV)-induced pulmonary exacerbations are common in cystic fibrosis (CF) and have been associated with impaired virus clearance by the CF airway epithelium in vitro. Here, we assess in vivo the association of RV prevalence and load with antiviral defense mechanisms, airway inflammation, and lung fu...

journal_title：Chest

authors： Kieninger E,Singer F,Tapparel C,Alves MP,Latzin P,Tan HL,Bossley C,Casaulta C,Bush A,Davies JC,Kaiser L,Regamey N

更新日期：2013-03-01 00:00:00

abstract：:Itraconazole is a new orally active antifungal triazole with impressive activity against Aspergillus spp. Six patients with allergic bronchopulmonary aspergillosis (ABPA), aged 14 to 49 years, were treated with oral itraconazole (200 mg twice daily) for a mean of 3.9 months (range, one to six months; three patients co...

journal_title：Chest

authors： Denning DW,Van Wye JE,Lewiston NJ,Stevens DA

更新日期：1991-09-01 00:00:00

abstract：:Extrapulmonary tuberculosis refers to Mycobacterium tuberculosis involving organs other than the lungs (eg, pleura, lymph nodes, genitourinary tract, abdomen, skin, joints and bones, or meninges). In non-HIV-endemic areas, where reactivation is the predominant mechanism of tuberculosis, pleural involvement occurs in 4...

journal_title：Chest

authors： Gleason JB,Tashtoush B,Mehta J,Savage E,Martinez F,Mehta AC

更新日期：2016-10-01 00:00:00

abstract：STUDY OBJECTIVES:To assess the incidence of tuberculosis in the native and immigrant populations of southern Israel in the period between 1992 and 1997, and to study the prevalence of drug resistance overall and among these subpopulations in the region in order to create guidelines for empirical antituberculous treatme...

journal_title：Chest

authors： Gilad J,Borer A,Riesenberg K,Peled N,Schlaeffer F

更新日期：2000-03-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the cause of pulmonary hypertension (PH) in systemic sclerosis (SSc) patients since PH can occur because of pulmonary arteriopathy, pulmonary parenchymal destruction, and left ventricular cardiac dysfunction. DESIGN AND SETTING:Consecutive case series in a university hospital. PATIENTS:N...

journal_title：Chest

authors： Strange C,Bolster M,Mazur J,Taylor M,Gossage JR,Silver R

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Assessment of patient preferences for attributes of asthma treatments. METHODS:Two hundred ninety-eight patients (age range, 18 to 60 years) from 15 centers in Sweden completed a questionnaire concerning their asthma, and ranked 18 alternative treatments using conjoint analysis. Patients were receiving treat...

journal_title：Chest

authors： Johansson G,Ställberg B,Tornling G,Andersson S,Karlsson GS,Fält K,Berggren F

更新日期：2004-03-01 00:00:00

abstract：:The clinical and histopathologic features of pulmonary amyloidosis were reviewed in 22 patients with systemic amyloidosis who came to autopsy. Eleven of 12 patients (92 percent) with primary amyloidosis had prominent interalveolar amyloid deposits. Symptoms attributable to these deposits were found in four cases (33 p...

journal_title：Chest

authors： Celli BR,Rubinow A,Cohen AS,Brody JS

更新日期：1978-11-01 00:00:00

abstract：CASE PRESENTATION:A 37-year-old man with poorly controlled type 2 diabetes presented with severe right-sided pleuritic chest pain, respiratory splinting, and cough. Two weeks earlier, he had been evaluated at an urgent care for cough and was prescribed a 5-day course of azithromycin for bronchitis. He then presented to...

journal_title：Chest

authors： Galant-Swafford J,Light M,Onaitis MW,Rawlings SA,Fierer J,Landsberg JW

更新日期：2019-07-01 00:00:00

abstract：STUDY OBJECTIVES:Pneumonia during chemotherapy-induced leukocytopenia is a major cause of overall treatment failure in patients with hematologic malignancies. To improve outcome in these high-risk patients, early diagnosis of pulmonary infiltrates and institution of adequate antimicrobial treatment are mandatory. To id...

journal_title：Chest

authors： Kiehl MG,Ostermann H,Thomas M,Birkfellner T,Kienast J

更新日期：1997-11-05 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a frequent cause of morbidity and mortality in patients with systemic sclerosis (SSc). PAH is generally considered to be a late complication of limited cutaneous SSc. This study identified and investigated a subset of SSc patients with early-onset PAH. METHODS:Clinic...

journal_title：Chest

authors： Hachulla E,Launay D,Mouthon L,Sitbon O,Berezne A,Guillevin L,Hatron PY,Simonneau G,Clerson P,Humbert M,French PAH-SSc Network.

更新日期：2009-11-01 00:00:00

abstract：:What is the meaning of these findings to the practicing chest physician? First, leukotrienes are potent airway constrictors; they are capable of reproducing the type of airway constriction observed in asthma. The role of leukotrienes in this regard has yet to be established, but experiments to test the importance of t...

journal_title：Chest

authors： Drazen JM

更新日期：1986-03-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the usefulness of radioaerosol ventilation scans for the detection and localization of air leaks from the lungs or bronchial tree. DESIGN:Selected patients with suspected air leaks underwent ventilation scans. Retrospective analysis of data was carried out. SETTING AND PATIENTS:Twenty-ei...

journal_title：Chest

authors： Mark JB,McDougall IR

更新日期：1997-02-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the safety and efficacy of sitaxsentan, an endothelin-A receptor antagonist, in a 12-week, open-label trial of patients with pulmonary arterial hypertension (PAH). PATIENTS:Six children and 14 adults with New York Heart Association (NYHA) functional class II, III, or IV primary pulmonary h...

journal_title：Chest

authors： Barst RJ,Rich S,Widlitz A,Horn EM,McLaughlin V,McFarlin J

更新日期：2002-06-01 00:00:00

abstract：:Bacterial pericarditis with cardiac tamponade is a life-threatening disorder that has been associated with a variety of organisms. There is usually an associated underlying condition or a seeding of the pericardium from an infection elsewhere. We report the development of cardiac tamponade and a subsequent pericardial...

journal_title：Chest

authors： Snyder RW,Braun TI

更新日期：1999-06-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the efficacy of mass spirometry use for the detection of airflow obstruction in a high-risk population. DESIGN:Free spirometry was offered to smokers who were > 39 years of age with a smoking history of > 10 pack-years. Action was preceded by the dissemination of information on the causes ...

journal_title：Chest

authors： Zieliñski J,Bednarek M,Know the Age of Your Lung Study Group.

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:This study attempts to determine the distribution of transudates vs exudates in pathologically proved malignant pleural effusions and the necessity for cytologic studies in patients with a transudative effusion. MATERIALS AND METHODS:A retrospective review of all cytologically positive malignant pleural effusi...

journal_title：Chest

authors： Assi Z,Caruso JL,Herndon J,Patz EF Jr

更新日期：1998-05-01 00:00:00

abstract：STUDY OBJECTIVES:Pulmonary fibrosis due to lipid peroxidation is a major symptom of paraquat intoxication. Ethane in the expired breath (exEth) reflects lipid peroxidation and may be a measure of the damage effected by oxygen radicals in acute lung injury. The purpose of this study was to evaluate the clinical efficacy...

journal_title：Chest

authors： Hong SY,Gil HW,Yang JO,Lee EY,Na JO,Seo KH,Kim YH

更新日期：2005-09-01 00:00:00

abstract：:In this study, the systemic and coronary hemodynamic changes associated with the administration of diltiazem, a recent calcium antagonist, were evaluated in three different situations as follows: following a 200 microgram/kg intravenous bolus of the drug in 12 open-chest anesthetized dogs; following two successive int...

journal_title：Chest

authors： Bourassa MG,Cote P,Theroux P,Tubau JF,Genain C,Waters DD

更新日期：1980-07-01 00:00:00