Abstract:
:A total of 161 patients with chronic obstructive pulmonary disease (COPD) plus 100 control subjects (identified during a study of heart disease in 6,860 Japanese-American men aged 52 to 75 years who were residing in Hawaii) were analyzed for phenotype in search of the antitrypsin gene Z, which has been shown to be associated with pulmonary emphysema in other racial groups. No carriers of the Z gene were found, and the question of whether the rarity or absence of this gene relates to a low frequency of COPD among Japanese-Americans is reviewed.
journal_name
Chestjournal_title
Chestauthors
Roberts A,Kagan A,Rhoads GG,Pierce JA,Bruce RMdoi
10.1378/chest.72.4.489subject
Has Abstractpub_date
1977-10-01 00:00:00pages
489-91issue
4eissn
0012-3692issn
1931-3543pii
S0012-3692(16)53614-9journal_volume
72pub_type
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