Antitrypsin and chronic obstructive pulmonary disease among Japanese-American men.

Abstract:

:A total of 161 patients with chronic obstructive pulmonary disease (COPD) plus 100 control subjects (identified during a study of heart disease in 6,860 Japanese-American men aged 52 to 75 years who were residing in Hawaii) were analyzed for phenotype in search of the antitrypsin gene Z, which has been shown to be associated with pulmonary emphysema in other racial groups. No carriers of the Z gene were found, and the question of whether the rarity or absence of this gene relates to a low frequency of COPD among Japanese-Americans is reviewed.

journal_name

Chest

journal_title

Chest

authors

Roberts A,Kagan A,Rhoads GG,Pierce JA,Bruce RM

doi

10.1378/chest.72.4.489

subject

Has Abstract

pub_date

1977-10-01 00:00:00

pages

489-91

issue

4

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)53614-9

journal_volume

72

pub_type

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