Intentional leaks in industrial masks have a significant impact on efficacy of bilevel noninvasive ventilation: a bench test study.

Abstract:

BACKGROUND:During noninvasive ventilation, nonintentional leaks have a detrimental effect on the efficacy of ventilation. A wide range of industrial masks are available, with intentional leaks of different importance. The potential impact of this variability in intentional leaks on performances of bilevel ventilators has not been assessed. OBJECTIVE:To measure intentional leaks in seven different industrial masks and determine whether higher leaks modify ventilator performance and quality of ventilation. METHODS:Seven interfaces connected to four ventilators, the VPAP III ST (ResMed; NorthRyde, Australia), the BiPAP Harmony (Respironics; Monroeville, PA), the SmartAir ST (Covidien/Airox; Pau, France), and the GoodKnight 425 ST Bilevel (Covidien/Tyco-Nellcor/Puritan Bennett; Pleasanton, CA), were adapted on a mannequin connected to a lung model (ASL5000, IngMar Medical; Pittsburgh, PA). Inspiratory positive airway pressure (IPAP) and expiratory positive airway pressure were 14 and 4 cm H(2)O, respectively. The lung model was set with a respiratory rate of 15 cycles per min and a duration of inspiration of 1 s in three simulated conditions (normal, restrictive, and obstructive). Inspiratory trigger delay and effort, capacity to achieve and maintain IPAP, expiratory cycling and tidal volume were analyzed for all masks and ventilators in the three simulated lung conditions. RESULTS:The level of intentional leaks in the seven masks ranged from 30 to 45 L/min for an IPAP of 14 cm H(2)O. Importance of leaks did not influence trigger performances. However, capacity to achieve and maintain IPAP was significantly decreased with all ventilators and in all simulated lung conditions when intentional leaks increased. This led to a maximum reduction in delivered tidal volume of 48 mL. Expiratory cycling was not affected by the level of intentional leaks except in obstructive lung conditions. CONCLUSION:Mask intentional leaks can impair efficacy of ventilation, especially when > 40 L/min.

journal_name

Chest

journal_title

Chest

authors

Borel JC,Sabil A,Janssens JP,Couteau M,Boulon L,Lévy P,Pépin JL

doi

10.1378/chest.08-1340

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

669-677

issue

3

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(09)60193-8

journal_volume

135

pub_type

杂志文章

相关文献

CHEST文献大全
  • Inhalation challenge with sulfidopeptide leukotrienes in human subjects.

    abstract::What is the meaning of these findings to the practicing chest physician? First, leukotrienes are potent airway constrictors; they are capable of reproducing the type of airway constriction observed in asthma. The role of leukotrienes in this regard has yet to be established, but experiments to test the importance of t...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.89.3.414

    authors: Drazen JM

    更新日期:1986-03-01 00:00:00

  • Acute cavitary histoplasmosis.

    abstract::A case of acute cavitary histoplasmosis in the upper lobes is documented. The relationship of this entity to chronic cavitary histoplasmosis is discussed. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.73.1.103

    authors: Davies SF,Sarosi GA

    更新日期:1978-01-01 00:00:00

  • Symptomatic coccidioidomycosis following a severe natural dust storm. An outbreak at the Naval Air Station, Lemoore, Calif.

    abstract::Eighteen newly diagnosed cases of symptomatic cocidioidomycosis developed two to four weeks following exposure to a severe natural dust storm. The population at risk consisted of 26,000 residents of the San Joaquin Valley with access to health care at the Naval Hospital, Lemoore, Calif. Eight patients were white, and ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.76.5.566

    authors: Williams PL,Sable DL,Mendez P,Smyth LT

    更新日期:1979-11-01 00:00:00

  • Left lung asthma.

    abstract::The chest radiograph of a woman with acute asthma showed signs of obstructive emphysema of the left lung. Fiberoptic bronchoscopy excluded obstruction of a large bronchus. The signs disappeared after antiasthmatic treatment, suggesting that they were caused by airway closure. In usual asthma, airway closure affects bo...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.6.1919

    authors: DiFrancia M,Barbier D,Orehek J

    更新日期:1993-12-01 00:00:00

  • Eosinophilic pneumonia without radiographic pulmonary infiltrates.

    abstract::In a 52-year-old man, chronic eosinophilic pneumonia (CEP), suggested by clinical history and marked eosinophilia in the peripheral blood and in the bronchoalveolar lavage fluid, has been diagnosed on open lung biopsy. Nevertheless, chest roentgenograms never showed any infiltration during the course of the disease. E...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.84.5.637

    authors: Dejaegher P,Derveaux L,Dubois P,Demedts M

    更新日期:1983-11-01 00:00:00

  • Localized Wegener's granulomatosis relapsing as diffuse massive intra-alveolar hemorrhage.

    abstract::In a 75-year-old patient presenting with a solitary pulmonary mass, a localized form of Wegener's granulomatosis was diagnosed after lobectomy. In the absence of extrapulmonary manifestations and after a benign postoperative course, the patients was discharged without medical treatment. Three months later, diffuse alv...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.3.955

    authors: Odeh M,Best LA,Kerner H,Bassan H,Oliven A

    更新日期:1993-09-01 00:00:00

  • Combined dose ratios of dopamine and dobutamine and right ventricular performance after cardiac surgery.

    abstract::The effect of combined administration of different dose ratios of dobutamine (DB) and dopamine (DA) (DB/DA ratio of 1:1; 1.5:0.5; 2:0; 0.5:1.5; and 0:2), with the added dose kept constant (10 micrograms/kg/min-20 micrograms/kg/min), on right ventricular function (measured by the thermal washout method with the aid of ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.5.1197

    authors: Imai T,Saitoh K,Kani H,Fujita T,Murata K

    更新日期:1992-05-01 00:00:00

  • A 34-Year-Old Woman With Hoarseness of Voice and an Abnormal Echocardiogram.

    abstract:CASE PRESENTATION:A 34-year-old woman presented for evaluation of several months of a hoarse voice and dyspnea on exertion that progressed over the last 3 years. She had a clinical diagnosis of asthma that had been treated with bronchodilators and inhaled corticosteroids for a few years. She continued to use her inhale...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2019.01.021

    authors: Jalil BA,Smith JS,El-Kersh K

    更新日期:2019-06-01 00:00:00

  • Surgical transsternal treatment of bronchopleural fistula postpneumonectomy.

    abstract::An original method of treatment for main bronchus fistula occurring after pneumonectomy was described in 1961. The operation is performed via a median sternotomy and the carinal region exposed. The main bronchi can then be divided in an area not involved with infection. We describe ten patients who underwent this proc...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.95.2.379

    authors: Beltrami V

    更新日期:1989-02-01 00:00:00

  • Association of Psychological Disorders With 30-Day Readmission Rates in Patients With COPD.

    abstract:BACKGROUND:There is a growing understanding of the prevalence and impact of psychological disorders on COPD. However, the role of these disorders in early readmission is unclear. METHODS:We analyzed data from 5% fee-for-service Medicare beneficiaries diagnosed with COPD (International Classification of Diseases, Ninth...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.15-0449

    authors: Singh G,Zhang W,Kuo YF,Sharma G

    更新日期:2016-04-01 00:00:00

  • High-intensity physical training in adults with asthma. A 10-week rehabilitation program.

    abstract::Twenty-six adults (23 to 58 years) with mild to moderate asthma underwent a 10-week supervised rehabilitation program, with emphasis on physical training. In the first 2 weeks, they exercised daily in an indoor swimming pool (33 degrees C) and received education about asthma, medication, and principles of physical tra...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.109.2.323

    authors: Emtner M,Herala M,Stålenheim G

    更新日期:1996-02-01 00:00:00

  • Changes in urinary uric acid excretion in obstructive sleep apnea before and after therapy with nasal continuous positive airway pressure.

    abstract:STUDY OBJECTIVE:To assess the utility of urinary uric acid excretion as a marker of nocturnal hypoxia in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) before and after the institution of nasal continuous positive airway pressure (CPAP). DESIGN:Prospective, open. SETTING:Sleep Disorders Laboratory, V...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.113.6.1604

    authors: Sahebjani H

    更新日期:1998-06-01 00:00:00

  • Safety and Efficacy of Remimazolam Compared With Placebo and Midazolam for Moderate Sedation During Bronchoscopy.

    abstract:BACKGROUND:While the complexity of flexible bronchoscopy has increased, standard options for moderate sedation medications have not changed in three decades. There is a need to improve moderate sedation while maintaining safety. Remimazolam was developed to address shortcomings of current sedation strategies. METHODS:...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.chest.2018.09.015

    authors: Pastis NJ,Yarmus LB,Schippers F,Ostroff R,Chen A,Akulian J,Wahidi M,Shojaee S,Tanner NT,Callahan SP,Feldman G,Lorch DG Jr,Ndukwu I,Pritchett MA,Silvestri GA,PAION Investigators.

    更新日期:2019-01-01 00:00:00

  • Elevated basic fibroblast growth factor levels in patients with pulmonary arterial hypertension.

    abstract:STUDY OBJECTIVES:Cellular growth in the vascular wall, including endothelial and smooth-muscle cell proliferation, is recognized as a component of the obstructive vasculopathy observed in the small vessels of the lungs in pulmonary arterial hypertension (PAH). We hypothesized that angiogenic growth factors may have a r...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.126.4.1255

    authors: Benisty JI,McLaughlin VV,Landzberg MJ,Rich JD,Newburger JW,Rich S,Folkman J

    更新日期:2004-10-01 00:00:00

  • The role of computer games in measuring spirometry in healthy and "asthmatic" preschool children.

    abstract:STUDY OBJECTIVES:To explore the role of respiratory interactive computer games in teaching spirometry to preschool children, and to examine whether the spirometry data achieved are compatible with acceptable criteria for adults and with published data for healthy preschool children, and whether spirometry at this age c...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.128.3.1146

    authors: Vilozni D,Barak A,Efrati O,Augarten A,Springer C,Yahav Y,Bentur L

    更新日期:2005-09-01 00:00:00

  • Impact of habitual cocaine smoking on the physiologic response to maximum exercise.

    abstract:BACKGROUND:Habitual smoking of alkaloidal cocaine (crack) has been reported to be associated with a number of cardiopulmonary complications that may not be clinically obvious but could potentially interfere with normal physiologic responses to exercise and thus impair maximum exercise performance. STUDY OBJECTIVE:To e...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.112.4.1008

    authors: Marques-Magallanes JA,Koyal SN,Cooper CB,Kleerup EC,Tashkin DP

    更新日期:1997-10-01 00:00:00

  • Health-related quality of life of persons with sarcoidosis.

    abstract:STUDY OBJECTIVES:To describe the health-related quality of life (HRQL) and mental health of persons with sarcoidosis, as well as to assess physician-patient agreement about the presence of sarcoidosis symptoms. DESIGN AND SETTING:Cross-sectional study at three university medical center outpatient pulmonary clinics. P...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.125.3.997

    authors: Cox CE,Donohue JF,Brown CD,Kataria YP,Judson MA

    更新日期:2004-03-01 00:00:00

  • Behçet's disease presenting with a pulmonary mass lesion.

    abstract::We report a case of Behçet's disease with pulmonary and splenic involvement. The radiologic presentation was quite different from the modes defined in the literature. A large, anteriorly located, well circumscribed ovoid mass was the x-ray film image of a large area of infarction with hemorrhage. The involved pulmonar...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.104.5.1635

    authors: Tüzün H,Yaman M,Gemicioglu B,Bozkurt K,Uygun N,Aktan K

    更新日期:1993-11-01 00:00:00

  • Tetralogy of Fallot with discrete fibrous subaortic stenosis.

    abstract::This is the first reported case of discrete fibrous subaortic stenosis in tetralogy of Fallot. Transaortic excision of the subaortic membrane was readily accomplished. To detect this and other forms of left ventricular outflow-tract obstruction in tetralogy of Fallot before surgery, routine selective left ventriculogr...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.69.4.543

    authors: Sanders JH,Van Praagh R,Sade RM

    更新日期:1976-04-01 00:00:00

  • Use of transesophageal echocardiography for diagnosis of traumatic aortic injury.

    abstract::This prospective study was conducted to describe the signs on transesophageal echocardiography (TEE) associated with traumatic aortic injury (TAI). Twenty-eight patients with TAI underwent TEE, and they were compared with a control group of 30 thoracic trauma patients without aortic injury. The TEE signs were classifi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.112.1.71

    authors: Goarin JP,Catoire P,Jacquens Y,Saada M,Riou B,Bonnet F,Coriat P

    更新日期:1997-07-01 00:00:00

  • Diagnosis of tracheoesophageal fistula by analysis of gastric air.

    abstract::Two patients receiving positive pressure ventilation experienced marked gaseous abdominal distension. Analysis of gases from the stomach, ventilator, and room air suggested that the gastric gases came from the ventilator in one patient. The diagnosis of tracheoesophageal fistula was confirmed by esophagoscopy. Analysi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.2.641

    authors: Kovitz KL,Siebens A,Brower RG

    更新日期:1993-08-01 00:00:00

  • Synchronized intermittent mandatory ventilation with and without pressure support ventilation in weaning patients with COPD from mechanical ventilation.

    abstract::This prospective study compared two weaning modalities in COPD patients requiring mechanical ventilation (MV) for acute respiratory failure. Nineteen patients with COPD were studied when their precipitating illness was controlled. Although they satisfied the conventional bedside weaning criteria, they could not tolera...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.105.4.1204

    authors: Jounieaux V,Duran A,Levi-Valensi P

    更新日期:1994-04-01 00:00:00

  • Implications of lower- and upper-limb training procedures in patients with chronic airway obstruction.

    abstract::In assessing the effectiveness of lower-limb and upper-limb nonspecific physical training, we have considered 3 objectives in this study: (1) determination of clinical and functional actual state in patients with chronic airway obstruction (CAO), before and after training; (2) determination of the tests, level of work...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.101.5_supplement.279s

    authors: Gimenez M,Predine E,Marchand M,Servera E,Ponz JL,Polu JM

    更新日期:1992-05-01 00:00:00

  • A randomized trial of delayed thoracic radiotherapy in complete responder patients with small-cell lung cancer. Petites Cellules Group.

    abstract::In small-cell lung cancer, the optimal combination of chemotherapy and radiotherapy is not clearly established. To assess the value of delayed thoracic radiotherapy, we performed a randomized clinical trial in 53 complete responder patients after eight courses of chemotherapy. Twenty-seven patients received a mean of ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.104.3.726

    authors: Lebeau B,Chastang C,Brechot JM,Capron F

    更新日期:1993-09-01 00:00:00

  • Humidifier lung. An outbreak in office workers.

    abstract::Symptoms consistent with hypersensitivity pneumonitis (HP) occurred in 26 of 50 employees working in a localized area of a large factory. This area was served by a single heating-cooling unit utilizing a water humidification system. The illness consisted of flu-like symptoms with fever, chills, headache, cough, dyspne...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.77.2.183

    authors: Ganier M,Lieberman P,Fink J,Lockwood DG

    更新日期:1980-02-01 00:00:00

  • Figure-eight kinking of the aorta (pseudocoarctation) coexistent with coarctation.

    abstract::An asymptomatic young man presented with a cardiac murmur and hypertension only in the right arm. Angiograms showed kinking of the aortic arch with a figure-eight appearance consistent with pseudocoarctation. Before the kinked segment, also demonstrated were a stenotic lesion in the aortic arch proximal to the left ca...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.97.5.1239

    authors: Tsai LM,Fu M,Chang CH,Hung JS

    更新日期:1990-05-01 00:00:00

  • Metastatic squamous cell carcinoma of the mediastinum with unknown primary tumor.

    abstract::Although metastatic carcinoma from an unknown primary tumor is known to occur, the combination of squamous cell carcinoma histologic findings and a mediastinal location is quite unusual. The evaluation of a case of a patient with a posterior mediastinal mass, eventually shown to be metastatic squamous cell carcinoma o...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.114.3.938

    authors: Blanco N,Kirgan DM,Little AG

    更新日期:1998-09-01 00:00:00

  • The effect of secondhand smoke exposure on markers of elastin degradation.

    abstract:BACKGROUND:Tobacco smoke is a major risk factor in the development of COPD. Secondhand smoke (SHS) exposure is a known risk factor in asthma, bronchitis, and coronary artery disease. Elastin is a recognized target for injury in COPD, and the amino acids desmosine and isodesmosine (D/I), which are specific for elastin d...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.10-2298

    authors: Slowik N,Ma S,He J,Lin YY,Soldin OP,Robbins RA,Turino GM

    更新日期:2011-10-01 00:00:00

  • Varying ejection fractions of both ventricles in paradoxical pulses: demonstration by radionuclide study.

    abstract::A noninvasive radionuclide study of the paradoxical pulse in pericardial effusion is described. The study shows complementary changes of the right and left ventricular ejection fractions in a patient with paradoxical pulse, supporting the theory that the inspiratory reduction of the left ventricular stroke volume is a...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.74.6.687

    authors: Yeh EL

    更新日期:1978-12-01 00:00:00

  • Detection of aortopulmonary window with ventricular septal defect by Doppler color flow imaging.

    abstract::Aortopulmonary window is a rare congenital cardiac anomaly. When it coexists with a ventricular septal defect, the accurate diagnosis of aortopulmonary window on the basis of clinical examination is difficult. We report the case of an infant who had an aortopulmonary window together with a ventricular septal defect. A...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.1.280

    authors: Horimi H,Hasegawa T,Shiraishi H,Endo H,Yanagisawa M

    更新日期:1992-01-01 00:00:00