Negative pressure pulmonary edema following bronchospasm.

Abstract:

:Negative pressure pulmonary edema (NPPE) is an important cause of noncardiogenic pulmonary edema but is rarely reported in the setting of bronchospasm. A 43-year-old woman with severe reactive airway disease suffered an episode of severe bronchospasm after endotracheal extubation following an otherwise uneventful general anesthetic. Subsequently, she developed clinical and radiographic signs of pulmonary edema in the absence of other symptoms of acute left-sided heart failure, leading to the diagnosis of noncardiogenic pulmonary edema. She received noninvasive positive pressure ventilation for a few hours, after which her clinical and radiologic signs and symptoms of pulmonary edema were greatly improved. This clinical scenario strongly suggests NPPE. We submit that it is possible to create NPPE by generating highly negative intrathoracic pressures in the setting of severe bronchospasm.

journal_name

Chest

journal_title

Chest

authors

Krodel DJ,Bittner EA,Abdulnour RE,Brown RH,Eikermann M

doi

10.1378/chest.11-0529

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1351-1354

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(11)60605-3

journal_volume

140

pub_type

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