The effects of macrolides on inflammatory cells.

abstract：:Diagnosis of the hereditary disorder alpha 1-antitrypsin (alpha 1AT) deficiency is critically dependent on quantification of serum levels of alpha 1AT, a 52-kDa antiprotease that serves to protect the lung from destruction by neutrophil elastase. Although the measurement of serum alpha 1AT levels is not difficult, the...

journal_title：Chest

authors： Brantly ML,Wittes JT,Vogelmeier CF,Hubbard RC,Fells GA,Crystal RG

更新日期：1991-09-01 00:00:00

abstract：:Respondents at an interactive symposium on pleural space infections (n = 339) at the 1991 American College of Chest Physicians Annual Scientific Assembly recorded their personal management preferences for hypothetical patients with empyema. The group's preference was to treat pleural sepsis from an anaerobic multilocu...

journal_title：Chest

authors： Strange C,Sahn SA

更新日期：1993-01-01 00:00:00

abstract：STUDY OBJECTIVES:The aim of this study was to develop an acute asthma index for utilization in the early differentiation between patients with poor and good therapeutic response in the emergency department (ED) setting. SETTING:The ED of a large tertiary-care hospital in Montevideo, Uruguay. PATIENTS AND DESIGN:The s...

journal_title：Chest

authors： Rodrigo G,Rodrigo C

更新日期：1998-10-01 00:00:00

abstract：:This study compared the bronchodilator effect in experimental canine asthma of dyphylline administered by aerosol and intravenous routes in doses producing equivalent concentrations of the drug in the plasma. Pulmonary resistance (RL) was calculated from simultaneous measurements of pressure and flow during fixed-volu...

journal_title：Chest

authors： Hirshman CA,Lawyer C,Downes H,Farbood A,Rodgers R,Gerber N

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-7 was reported to be a key molecule in the pathogenesis of idiopathic pulmonary fibrosis (IPF) based on the result of microarray analysis and knockout mice. However, the role of MMP-7 has not been determined in other types of idiopathic interstitial pneumonia (IIP). The aim of ...

journal_title：Chest

authors： Huh JW,Kim DS,Oh YM,Shim TS,Lim CM,Lee SD,Koh Y,Kim WS,Kim WD,Kim KR

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has been documented to cause community-acquired pneumonias (CAP), notable for necrotizing features. The frequency of occurrence, risk factors, and optimal treatment of CA-MRSA CAP are unclear. METHODS:This was a retrospective analysis ...

journal_title：Chest

authors： Lobo LJ,Reed KD,Wunderink RG

更新日期：2010-07-01 00:00:00

abstract：:Clinicians who auscultate the chest of normal children note that the frequency content of their breath sounds appears to vary with age. Because these changes have not been systematically documented before, we recorded and analyzed inspiratory breath sounds in 35 children (0 to 13 years) and five adults (34 to 43 years...

journal_title：Chest

authors： Hidalgo HA,Wegmann MJ,Waring WW

更新日期：1991-10-01 00:00:00

abstract：:A 66-year-old woman was cared for at two referral institutions following a witnessed cardiac arrest in a local emergency department. Despite aggressive initial care, she failed to regain consciousness during a 28-day course. Based on an erroneous neurologic diagnosis of anoxic encephalopathy, pessimism regarding likel...

journal_title：Chest

authors： Dunn WF,Adams SC,Adams RW

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:It has been postulated that differences in provocative concentration of methacholine causing a 20% fall in FEV1 (PC20) values between the dosimeter method and tidal breathing method might be due to differences in the dose of agonist delivered to the mouth. The aim of the present study was to determine the in...

journal_title：Chest

authors： Prieto L,Lopez V,Llusar R,Rojas R,Marin J

更新日期：2008-10-01 00:00:00

abstract：STUDY OBJECTIVE:To examine the hemodynamic and metabolic short-term effects of hypophosphatemia correction in patients with septic shock receiving catecholamine therapy. DESIGN:Prospective, single cohort study. SETTING:ICU, university hospital. PATIENTS:Ten patients with septic shock and hypophosphatemia below 2 mg/...

journal_title：Chest

authors： Bollaert PE,Levy B,Nace L,Laterre PF,Larcan A

更新日期：1995-06-01 00:00:00

abstract：STUDY OBJECTIVE:Our objective was to compare the efficacy of ultrahigh frequency ventilation (UHFV) (frequencies > 3 Hz) with respect to oxygenation, airway pressures, and hemodynamic parameters in patients with adult respiratory distress syndrome (ARDS) who were not responding to conventional ventilation. DESIGN:We u...

journal_title：Chest

authors： Gluck E,Heard S,Patel C,Mohr J,Calkins J,Fink MP,Landow L

更新日期：1993-05-01 00:00:00

abstract：:Electrocardiogram changes and pharmacologic responses were studied in 28 cases of brain death. Cardiac activity in this condition is possibly determined by the dynamic balance between the depressant action of hypothermia and the stimulating action of the sympathetic nervous system (without any vagal or central influen...

journal_title：Chest

authors： Drory Y,Ouaknine G,Kosary IZ,Kellermann JJ

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...

journal_title：Chest

authors： Faust HE,Reilly JP,Anderson BJ,Ittner CAG,Forker CM,Zhang P,Weaver BA,Holena DN,Lanken PN,Christie JD,Meyer NJ,Mangalmurti NS,Shashaty MGS

更新日期：2020-01-01 00:00:00

abstract：:We assessed the importance of Streptococcus pneumoniae and immunologic response to 14-valent pneumococcal vaccine in a randomized (saline placebo or vaccine) double-blind pilot study involving 103 patients with chronic obstructive pulmonary disease (COPD). Antibody titers, the flora of the sputum, respiratory infectio...

journal_title：Chest

authors： Davis AL,Aranda CP,Schiffman G,Christianson LC

更新日期：1987-08-01 00:00:00

abstract：:Since first described in 1984, nontraumatic pneumothoraces in patients with AIDS has become more common. When compared with spontaneous pneumothorax in the general population, pneumothoraces in patients with AIDS are often complicated by prolonged air leaks as well as higher recurrence rates. Chemical pleurodesis has ...

journal_title：Chest

authors： Read CA,Reddy VD,O'Mara TE,Richardson MS

更新日期：1994-03-01 00:00:00

abstract：:An asymptomatic young man presented with a cardiac murmur and hypertension only in the right arm. Angiograms showed kinking of the aortic arch with a figure-eight appearance consistent with pseudocoarctation. Before the kinked segment, also demonstrated were a stenotic lesion in the aortic arch proximal to the left ca...

journal_title：Chest

authors： Tsai LM,Fu M,Chang CH,Hung JS

更新日期：1990-05-01 00:00:00

abstract：:The serum concentration of angiotensin-converting enzyme is frequently elevated in individuals with active sarcoidosis. The enzyme is presumably actively synthesized by the epithelioid and giant cells of the granuloma. Hypersensitivity pneumonitis, resulting from the inhalation of antigens from pigeons by susceptible ...

journal_title：Chest

authors： McCormick JR,Thrall RS,Ward PA,Moore VL,Fink JN

更新日期：1981-10-01 00:00:00

abstract：:To assess the effects of intravenous aminophylline on the sinus node, 12 patients with clinical and Holter monitor-documented sick sinus syndrome were studied (1) during the control state, (2) after pharmacologic autonomic blockade and (3) 5 min after intravenous administration of aminophylline. The effects of aminoph...

journal_title：Chest

authors： Lai WT,Lai HM,Lin CT,Sheu SH,Hwang YS

更新日期：1991-04-01 00:00:00

abstract：INTRODUCTION:The diaphragm plays a pivotal role in weaning and successful extubation. We hypothesized that ultrasonographic evaluation of the movements of the diaphragm by measuring liver/spleen displacement during spontaneous breathing trials is a good predictor for extubation outcome. PATIENTS AND METHODS:The studie...

journal_title：Chest

authors： Jiang JR,Tsai TH,Jerng JS,Yu CJ,Wu HD,Yang PC

更新日期：2004-07-01 00:00:00

abstract：:A 56-year-old woman presented to our hospital with a 4-month history of worsening chest pain. She denied having any respiratory symptoms, such as dyspnea, sputum, cough, or hemoptysis, or any history of smoking or exposure to dusts. One year previously she had a vertebral fracture. There was no specific family history...

journal_title：Chest

authors： Kato T,Muto H,Hishima T,Kawashima M,Nagai H,Matsui H,Shimada M,Hebisawa A,Doki N,Miyawaki S,Ohashi K

更新日期：2018-05-01 00:00:00

abstract：:To determine whether continuous Fick cardiac output measurement is applicable to exercise testing, cardiac output data obtained by the continuous Fick method (Qcf) during exercise were compared with data obtained by the thermodilution method (Qth). Seventeen patients with old myocardial infarction underwent a 1-min or...

journal_title：Chest

authors： Nakanishi N,Yoshioka T,Okano Y,Nishimura T

更新日期：1993-08-01 00:00:00

abstract：:Solitary extramedullary plasmacytomas are uncommon neoplasms. They occur most frequently in the upper aerodigestive tract and account for 4% of the nonepithelial tumors in this site. The evolution of a plasmacytoma is unsteady and symptoms at presentation have included dystonia, dysphagia, oral pain, cough, and dyspne...

journal_title：Chest

authors： Byrd RP Jr,Roy TM,Bentz W,Mehta JB

更新日期：1996-06-01 00:00:00

abstract：:A 60-year-old man developed histologic lesions characteristic of acute febrile neutrophilic dermatosis in skin and lung during preleukemic and leukemic phases of acute myeloid leukemia. These lesions showed improvement and resolution during oral prednisone therapy, requiring higher doses during each relapse. The respo...

journal_title：Chest

authors： Lazarus AA,McMillan M,Miramadi A

更新日期：1986-12-01 00:00:00

abstract：STUDY OBJECTIVE:To investigate the efficacy and safety profiles of corticosteroid therapy in severe acute respiratory syndrome (SARS) patients. DESIGN:Four hundred one of 1,278 SARS cases treated in Guangzhou China between December 2002 and June 2003 fulfilled the diagnostic criteria issued by the World Health Organiz...

journal_title：Chest

authors： Chen RC,Tang XP,Tan SY,Liang BL,Wan ZY,Fang JQ,Zhong N

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Little is known about the prevalence, predictors, and outcomes of late vasopressor administration which evolves after admission to the ICU. RESEARCH QUESTION:What is the epidemiology of late vasopressor administration in the ICU? STUDY DESIGN AND METHODS:We retrospectively studied a cohort of veterans admi...

journal_title：Chest

authors： Viglianti EM,Bagshaw SM,Bellomo R,McPeake J,Molling DJ,Wang XQ,Seelye S,Iwashyna TJ

更新日期：2020-08-01 00:00:00

abstract：STUDY OBJECTIVES:Lymphangioleiomyomatosis (LAM) is a rare disorder of unknown etiology, affecting almost exclusively women of childbearing age, that is associated with the proliferation of spindle cells and cystic changes in the affected lung. The underlying processes that contribute to this disease are poorly understo...

journal_title：Chest

authors： Evans SE,Colby TV,Ryu JH,Limper AH

更新日期：2004-03-01 00:00:00

abstract：:The incidence of distal esophageal adenocarcinoma and primary proximal gastric carcinoma has increased substantially in the past 15 years, particularly in North America and in some European countries. Patients with curatively resected cancer consistently have a 10 to 20% 5-year survival rate. Radiation therapy alone s...

journal_title：Chest

authors： Ajani JA

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Portable monitoring is a convenient means for diagnosing sleep apnea. However, data on whether one night of monitoring is sufficiently precise for the diagnosis of sleep apnea are limited. RESEARCH QUESTION:The current study sought to determine the variability and misclassification in disease severity over ...

journal_title：Chest

authors： Punjabi NM,Patil S,Crainiceanu C,Aurora RN

更新日期：2020-07-01 00:00:00

abstract：:Although nearly 3,000 e-cigarette-related hospitalizations have been reported in North America, the long-term outcomes in these patients have not been described. We followed an 18-year-old boy who survived acute critical illness and respiratory failure related to 5 months of e-cigarette use. Chronic irreversible airfl...

journal_title：Chest

authors： Eddy RL,Serajeddini H,Knipping D,Landman ST,Bosma KJ,Mackenzie CA,Dhaliwal I,Parraga G

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the incidence of catamenial pneumothorax (CP) among women who have been referred for the surgical treatment of spontaneous pneumothorax (SP) and to study its pathogenic mechanisms. DESIGN:A prospective study of women of reproductive age who have been referred to our center for the surgical treat...

journal_title：Chest

authors： Alifano M,Roth T,Broët SC,Schussler O,Magdeleinat P,Regnard JF

更新日期：2003-09-01 00:00:00