Is sick sinus syndrome an adenosine-mediated disease? Effects of intravenous aminophylline on sick sinus node function after pharmacologic autonomic blockade.

abstract：BACKGROUND:Altitude exposure is associated with mild pulmonary hypertension and decreased exercise capacity. We tested the hypothesis that pulmonary vascular resistance (PVR) contributes to decreased exercise capacity in hypoxic healthy subjects. METHODS:An incremental cycle ergometer cardiopulmonary exercise test and...

journal_title：Chest

authors： Faoro V,Boldingh S,Moreels M,Martinez S,Lamotte M,Unger P,Brimioulle S,Huez S,Naeije R

更新日期：2009-05-01 00:00:00

abstract：:We wanted to determine the efficacy of dobutamine infusions and Prbc transfusions on splanchnic tissue oxygen utilization by measuring gastric pHi. Physiologic parameters and pHi measurements via the use of a gastric tonometer were obtained in 21 septic patients before and after the administration of a dobutamine infu...

journal_title：Chest

authors： Silverman HJ,Tuma P

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Walking is a familiar daily activity that is generally limited by breathlessness, whereas cycling is an uncommon physical effort typically limited by leg discomfort. The hypothesis was that patients with COPD would exhibit greater improvements in exercise endurance and relief of breathlessness with bronchodi...

journal_title：Chest

authors： Zhang X,Waterman LA,Ward J,Baird JC,Mahler DA

更新日期：2010-06-01 00:00:00

abstract：:The factors that contribute to the symptoms of breathlessness and fatigue, and that limit exercise capacity in patients with chronic heart failure are poorly understood. Recent evidence suggests that the major mechanism is not related to central hemodynamics but to a reduction of skeletal muscle mass and diminished bl...

journal_title：Chest

authors： Poole-Wilson PA,Buller NP,Lindsay DC

更新日期：1992-05-01 00:00:00

abstract：STUDY OBJECTIVES:(1) To describe a new percutaneous pleural biopsy technique to obtain multiple-site parietal pleural biopsy specimens in patients with pleural effusion (PE), and (2) to evaluate its effectiveness and safety compared to current techniques. DESIGN:Prospective interventional study. SETTING:University te...

journal_title：Chest

authors： Uthaman B,Behbehani N,Abal A,Madda J,Khan S

更新日期：2004-05-01 00:00:00

abstract：:This article is the first in a planned series from the Section on Lung Cancer of the ACCP addressing the important and clinically relevant aspects of what is now the most common malignancy in the world, lung cancer. This initial report addresses the problem of staging of lung cancer. Staging, or identifying the anatom...

journal_title：Chest

authors： Little AG,Stitik FP

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Bronchoscopy is a useful tool for the diagnosis of lesions near central airways; however, the diagnostic accuracy of these procedures for peripheral pulmonary lesions (PPLs) is a matter of ongoing debate. In this setting, electromagnetic navigation bronchoscopy (ENB) is a technique used to navigate and obtai...

journal_title：Chest

authors： Folch EE,Labarca G,Ospina-Delgado D,Kheir F,Majid A,Khandhar SJ,Mehta HJ,Jantz MA,Fernandez-Bussy S

更新日期：2020-10-01 00:00:00

abstract：:A 79-year-old woman in the course of a syncope evaluation is shown to have a trazodone-related cardiac arrhythmia confirmed by drug rechallenge. This nontricyclic antidepressant should be considered as potentially arrhythmogenic despite its generally favorable cardiovascular profile. ...

journal_title：Chest

authors： Vitullo RN,Wharton JM,Allen NB,Pritchett EL

更新日期：1990-07-01 00:00:00

abstract：STUDY OBJECTIVES:Surgical resection remains the treatment of choice for anatomically resectable non-small cell lung cancer. However, the presence of associated comorbid conditions increases the risk of death and surgical complications. Several studies have evaluated the usefulness of preoperative exercise testing for p...

journal_title：Chest

authors： Win T,Jackson A,Sharples L,Groves AM,Wells FC,Ritchie AJ,Laroche CM

更新日期：2005-04-01 00:00:00

abstract：STUDY OBJECTIVE:To ascertain the incidence, types, morbidity, and mortality of infectious episodes in isolated lung transplant recipients. DESIGN:Retrospective chart review of patients who have undergone transplants over a six-year period in one institution. PATIENTS:Twenty-three single and 17 double lung transplants...

journal_title：Chest

authors： Maurer JR,Tullis DE,Grossman RF,Vellend H,Winton TL,Patterson GA

更新日期：1992-04-01 00:00:00

abstract：:Ischemic myocardium undergoes many physiologic changes, including alterations in contractile function, histologic condition, and oxygen utilization. Reperfusion of ischemic myocardium may reverse some of these changes; however, the level of reperfusion needed for adequate functional recovery, as opposed to myocyte sal...

journal_title：Chest

authors： Rohs TJ Jr,Benedict MB,Bolling SF

更新日期：1997-10-01 00:00:00

abstract：:We describe a neonate with an accessory diaphragm, a rare congenital anomaly. It almost always occurs in the right hemithorax, which appears diffusely hazy on the anterior chest roentgenogram. The lateral chest roentgenogram is essential in the diagnosis of this condition. ...

journal_title：Chest

authors： Hopkins RL,Davis SH

更新日期：1988-09-01 00:00:00

abstract：:Three sets of guidelines for the management of COPD that are widely recognized (from the European Respiratory Society [ERS], American Thoracic Society [ATS], and British Thoracic Society [BTS]) are reviewed and compared. None of the documents uses classic evidence-based documentation, and, in many instances, the recom...

journal_title：Chest

authors： Ferguson GT

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Early high-dose IV vitamin C is being investigated as adjuvant therapy in patients who are critically ill, but the optimal dose and infusion method are unclear. The primary aim of this study was to describe the dose-plasma concentration relationship and safety of four different dosing regimens. METHODS:This...

journal_title：Chest

authors： de Grooth HJ,Manubulu-Choo WP,Zandvliet AS,Spoelstra-de Man AME,Girbes AR,Swart EL,Oudemans-van Straaten HM

更新日期：2018-06-01 00:00:00

abstract：:The resurgence of tuberculosis (TB) in the early 1990s, including multidrug-resistant strains, led health officials to recommend the use of involuntary detention for persistently nonadherent patients. Using a series of recently published articles on the subject, this paper offers some opinions on how detention program...

journal_title：Chest

authors： Lerner BH

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Balance deficits and an increased fall risk are well documented in individuals with COPD. Despite evidence that balance training programs can improve performance on clinical balance tests, their minimal clinically important difference (MCID) is unknown. The aim of this study was to determine the MCID of the ...

journal_title：Chest

authors： Beauchamp MK,Harrison SL,Goldstein RS,Brooks D

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:To develop an evidence-based approach to follow-up of patients after curative intent therapy for lung cancer. METHODS:Guidelines on lung cancer diagnosis and management published between 2002 and December 2005 were identified by a systematic review of the literature, and supplemental material appropriate to...

journal_title：Chest

authors： Rubins J,Unger M,Colice GL,American College of Chest Physicians.

更新日期：2007-09-01 00:00:00

abstract：:In patients with chronic obstructive pulmonary disease (COPD) studied at rest, nifedipine releases hypoxic pulmonary vasoconstriction (HPV) and worsens gas exchange. During exercise, this drug lowers pulmonary hypertension, but the effects of this lower pulmonary vascular tone on ventilation-perfusion (VA/Q) relations...

journal_title：Chest

authors： Agustí AG,Barberá JA,Roca J,Wagner PD,Guitart R,Rodriguez-Roisín R

更新日期：1990-02-01 00:00:00

abstract：:To facilitate the studies in cell biology and drug sensitivity of non-small cell lung cancer, cell samples from 55 patients have been used to establish cell lines in culture using a chemically defined medium (ACL-4). A total of 20 cell lines (36 percent) were directly established and characterized: 14 (44 percent) fro...

journal_title：Chest

authors： Masuda N,Fukuoka M,Takada M,Kudoh S,Kusunoki Y

更新日期：1991-08-01 00:00:00

abstract：:The history of the use of beta-blockers for congestive heart failure, beginning with the innovative seminal study by the Swedish group in 1975 to studies in 1995, is reviewed and shows that almost all trials favored the use of beta-blockers. They tended to demonstrate an increase in ejection fraction, a decrease in le...

journal_title：Chest

authors： Constant J

更新日期：1998-03-01 00:00:00

abstract：:Substantial experimental evidence supports the idea that the fibroblast may play a significant role in the vascular response to injury, especially under hypoxic conditions. Fibroblasts have the ability to rapidly respond to hypoxic stress and to modulate their function to adapt rapidly to local vascular needs. Fibrobl...

journal_title：Chest

authors： Stenmark KR,Gerasimovskaya E,Nemenoff RA,Das M

更新日期：2002-12-01 00:00:00

abstract：STUDY OBJECTIVES:To determine and compare the values of positron emission tomography (PET) with F-18 fluorodeoxyglucose (FDG) and CT for predicting clinical outcome of patients with aggressive lymphoma undergoing salvage cytoreductive chemotherapy followed by high-dose chemotherapy and autologous stem-cell transplantat...

journal_title：Chest

authors： Filmont JE,Czernin J,Yap C,Silverman DH,Quon A,Phelps ME,Emmanouilides C

更新日期：2003-08-01 00:00:00

abstract：:POC testing provides an opportunity for clinicians and laboratorians to work together to consider how best to serve the patients within an individual institution. Each health system has unique characteristics relative to patient population, as well as a unique laboratory structure. If physicians, nurses, laboratorians...

journal_title：Chest

authors： Kost GJ,Ehrmeyer SS,Chernow B,Winkelman JW,Zaloga GP,Dellinger RP,Shirey T

更新日期：1999-04-01 00:00:00

abstract：:The preoperative physiologic assessment of a patient being considered for surgical resection of lung cancer must consider the immediate perioperative risks from comorbid cardiopulmonary disease, the long-term risks of pulmonary disability, and the threat to survival due to inadequately treated lung cancer. As with any...

journal_title：Chest

authors： Beckles MA,Spiro SG,Colice GL,Rudd RM,American College of Chest Physicians.

更新日期：2003-01-01 00:00:00

abstract：:We describe three cases of acute uncomplicated bacterial pneumonia due to viridans streptococci in previously healthy adults, which were indistinguishable from those caused by other well-known respiratory pathogens. On arrival, all of these patients were treated with IV aqueous penicillin based on Gram stain of sputum...

journal_title：Chest

authors： Sarkar TK,Murarka RS,Gilardi GL

更新日期：1989-10-01 00:00:00

abstract：:Elimination half-life and apparent volume of distribution of theophylline were determined in ten healthy volunteers who used smokeless tobacco (snuff or chewing tobacco) regularly but did not smoke cigarettes. Serum concentrations of the acute phase reactant alpha 1-acid glycoprotein (AAG) were also measured. The elim...

journal_title：Chest

authors： Parish RC,Terrell JR,Brown WJ Jr

更新日期：1989-06-01 00:00:00

abstract：:The pulmonary status of 178 asymptomatic asthmatic children with normal time-volume spirograms was further evaluated using flow-volume loops, body plethysmographic studies, and blood gas tensions in arterialized capillary blood. Residual volume (RV) was abnormal in 26%, total lung capacity (TLC) in 33%, RV/TLC% in 41%...

journal_title：Chest

authors： Cooper DM,Cutz E,Levison H

更新日期：1977-03-01 00:00:00

abstract：:This study was designed to compare the efficacy of coronary thrombolysis obtained with i.v. administration of three dose regimens of recombinant tissue plasminogen activator (rtPA). Although many studies have confirmed the efficacy of thrombolytic therapy in treatment of acute myocardial infarction, few prospective st...

journal_title：Chest

authors： Prewitt RM,Schick U,Ducas J

更新日期：1996-02-01 00:00:00

abstract：:Complications following open chest massage in patients with porcine xenografts in the mitral location have not been previously described. The authors report a case of cardiac resuscitation following mitral valve replacement with a stented porcine valve. The patient died following brief closed chest, and then, prolonge...

journal_title：Chest

authors： Wild LM,Lajos TZ,Lee AB Jr,Wright J

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVE:To investigate the associations of maternal and grandmaternal smoking before, during, and after pregnancy with childhood asthma. DESIGN, SETTING, AND PARTICIPANTS:We conducted a case-control study nested within the Children's Health Study in southern California. The case patients consisted of 338 children wi...

journal_title：Chest

authors： Li YF,Langholz B,Salam MT,Gilliland FD

更新日期：2005-04-01 00:00:00