Clinical pharmacokinetics of theophylline and levels of alpha 1-acid glycoprotein in smokeless tobacco users.

abstract：OBJECTIVE:Patients with COPD are at risk for cardiovascular events. This is attributed to increased systemic inflammation. The course of COPD is punctuated by exacerbations, which further increase systemic inflammation, but the risk of vascular events in the postexacerbation period has never been defined. METHODS:We a...

journal_title：Chest

authors： Donaldson GC,Hurst JR,Smith CJ,Hubbard RB,Wedzicha JA

更新日期：2010-05-01 00:00:00

abstract：:To assess the clinical correlates and therapeutic outcome of new postoperative supraventricular tachyarrhythmias, 916 patients who were in sinus rhythm throughout the course of surgery were prospectively followed after major noncardiac surgery. The 35 patients (4 percent) who developed new postoperative supraventricul...

journal_title：Chest

authors： Goldman L

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:COPD is accepted to be a multicomponent disease with various comorbidities. To our knowledge, the contribution of the GI tract to the systemic manifestation of COPD has never been investigated. This metabolically active organ may experience recurring local oxygen deficits during daily life, leading to distur...

journal_title：Chest

authors： Rutten EPA,Lenaerts K,Buurman WA,Wouters EFM

更新日期：2014-02-01 00:00:00

abstract：:We studied hypoxic and hypercapnic ventilatory drives in 22 eucapnic obese subjects (14 female and eight male subjects) referred for weight reduction therapy and 23 normal subjects (eight female and 15 male subjects). In the female subjects, both occlusion pressure, currently used as an indicator of ventilatory drive,...

journal_title：Chest

authors： Kunitomo F,Kimura H,Tatsumi K,Kuriyama T,Watanabe S,Honda Y

更新日期：1988-05-01 00:00:00

abstract：:A massive GI bleed secondary to a Dieulafoy's lesion developed in a 77-year-old woman. Fifteen days later, massive pulmonary emboli developed. We describe successful thrombolytic treatment of her pulmonary emboli without complicating GI hemorrhage. ...

journal_title：Chest

authors： Levin MS,Vernovsky I,Beer DJ

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Chronic tobacco smoke exposure results in a broad range of lung pathologies including emphysema, airway disease and parenchymal fibrosis as well as a multitude of extra-pulmonary comorbidities. Prior work using CT imaging has identified several clinically relevant subgroups of smoking related lung disease, b...

journal_title：Chest

authors： Billatos E,Ash SY,Duan F,Xu K,Romanoff J,Marques H,Moses E,Han MK,Regan EA,Bowler RP,Mason SE,Doyle TJ,San José Estépar R,Rosas IO,Ross JC,Xiao X,Liu H,Liu G,Sukumar G,Wilkerson M,Dalgard C,Stevenson C,Whitney

更新日期：2020-09-16 00:00:00

abstract：:Five different volumes of test solutions (1 to 3 ml) containing 15 mg of metaproterenol were placed in each of five different nebulizers. The time to complete nebulization and the amount of drug delivered varied considerably, depending upon the initial volume of solution placed in the nebulizer. Small volumes (1 ml) w...

journal_title：Chest

authors： Kradjan WA,Lakshminarayan S

更新日期：1985-04-01 00:00:00

abstract：STUDY OBJECTIVES:To explore the role of respiratory interactive computer games in teaching spirometry to preschool children, and to examine whether the spirometry data achieved are compatible with acceptable criteria for adults and with published data for healthy preschool children, and whether spirometry at this age c...

journal_title：Chest

authors： Vilozni D,Barak A,Efrati O,Augarten A,Springer C,Yahav Y,Bentur L

更新日期：2005-09-01 00:00:00

abstract：:Relapsing polychondritis (RP) is a rare disease characterized by recurrent inflammation and destruction of the cartilaginous structures. Tracheobronchial chondritis is a dreaded complication of RP. We wish to report a case of RP of the trachea and bronchi which was treated with nasal continuous positive airway pressur...

journal_title：Chest

authors： Adliff M,Ngato D,Keshavjee S,Brenaman S,Granton JT

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:There is controversy about whether therapy with inhaled corticosteroids (ICSs) modifies the natural history of COPD, characterized by an accelerated decline in FEV(1). METHODS:The Inhaled Steroids Effect Evaluation in COPD (ISEEC) study is a pooled study of patient-level data from seven long-term randomized...

journal_title：Chest

authors： Soriano JB,Sin DD,Zhang X,Camp PG,Anderson JA,Anthonisen NR,Buist AS,Burge PS,Calverley PM,Connett JE,Petersson S,Postma DS,Szafranski W,Vestbo J

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Population-based studies have documented an association between obesity and an increased prevalence of asthma in women. METHODS:We prospectively studied 58 obese women with a body mass index of > 30 kg/m(2), 24 of whom had asthma, who were enrolled in an intensive 6-month weight loss program to determine wh...

journal_title：Chest

authors： Aaron SD,Fergusson D,Dent R,Chen Y,Vandemheen KL,Dales RE

更新日期：2004-06-01 00:00:00

abstract：:Although in SLE pericarditis is common, cardiac tamponade is rare and its usual treatment has been effusion drainage. A 19-year-old girl presenting with cardiac tamponade was diagnosed with SLE. Treatment with indomethacin rapidly reduced the hemodynamic compromise, avoiding the need for pericardiocentesis. ...

journal_title：Chest

authors： Porcel JM,Selva A,Tornos MP,Galve E,Soler-Soler J

更新日期：1989-11-01 00:00:00

abstract：:The use of portable monitors (PM) devices has been demonstrated in a wide variety of investigational settings with varying results. While most devices correlate very well with in-laboratory polysomnography, some still misclassify a significant numbers of patients and have lower sensitivity. In addition, the failure ra...

journal_title：Chest

authors： Ahmed M,Patel NP,Rosen I

更新日期：2007-11-01 00:00:00

abstract：:A post-right pneumonectomy syndrome is described which manifests symptoms of exertional dyspnea and inspiratory stridor on rapid inspiration. These symptoms were associated with marked rightward and posterior deviation of the trachea, over-distention of the left lung with its herniation into the right side of the ches...

journal_title：Chest

authors： Wasserman K,Jamplis RW,Lash H,Brown HV,Cleary MG,Lafair J

更新日期：1979-01-01 00:00:00

abstract：:The prevalence of periodic limb movements (PLM) during sleep and their effect on sleep and daytime alertness were determined in 23 men with severe, stable congestive heart failure (CHF) and 9 healthy control subjects. Each subject had overnight polysomnography and the following day completed a subjective assessment of...

journal_title：Chest

authors： Hanly PJ,Zuberi-Khokhar N

更新日期：1996-06-01 00:00:00

abstract：:Six young cocaine users, median age 35.5 years (range 27 to 44 years) experienced acute myocardial infarction. The close temporal correlation in two cases between cocaine use and clinical infarction and the relative paucity of atherosclerotic blockage of the coronary arteries in the others, as demonstrated by autopsy ...

journal_title：Chest

authors： Kossowsky WA,Lyon AF

更新日期：1984-11-01 00:00:00

abstract：:Neurosarcoidosis occurs in approximately 5% of patients with systemic sarcoidosis. A review of medical literature shows that intracranial mass-like lesions secondary to sarcoidosis are quite rare. CT and MRI scanning would suggest that this manifestation of neurosarcoidosis may be more common than previously realized....

journal_title：Chest

authors： Veres L,Utz JP,Houser OW

更新日期：1997-02-01 00:00:00

abstract：:A series of 15 patients with life threatening, massive hemoptysis is reported. Thirteen of these patients underwent immediate operative treatment with only three deaths. One died after bronchoscopic identification of the bleeding site while awaiting elective thoracotomy. The other patient left the hospital against med...

journal_title：Chest

authors： McCollun WB,Mattox KL,Guinn GA,Beall AC Jr

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Surgical patients with OSA are at increased risk for perioperative complications. Postoperative supplemental oxygen is commonly used, but it may contribute to respiratory depression in patients with OSA receiving opioids. The objective of the study is to investigate the effect of postoperative supplemental o...

journal_title：Chest

authors： Liao P,Wong J,Singh M,Wong DT,Islam S,Andrawes M,Shapiro CM,White DP,Chung F

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:COPD is characterized by chronic inflammation. In vitro and ex vivo observations suggest that this inflammatory response is partially resistant to the effect of corticosteroids and that low-dose theophylline can restore this response via enhancement of histone deacetylase (HDAC) activity. Whether this occurs...

journal_title：Chest

authors： Cosío BG,Shafiek H,Iglesias A,Yanez A,Córdova R,Palou A,Rodriguez-Roisin R,Peces-Barba G,Pascual S,Gea J,Sibila O,Barnes PJ,Agusti A

更新日期：2016-07-01 00:00:00

abstract：STUDY OBJECTIVES:Pneumonia during chemotherapy-induced leukocytopenia is a major cause of overall treatment failure in patients with hematologic malignancies. To improve outcome in these high-risk patients, early diagnosis of pulmonary infiltrates and institution of adequate antimicrobial treatment are mandatory. To id...

journal_title：Chest

authors： Kiehl MG,Ostermann H,Thomas M,Birkfellner T,Kienast J

更新日期：1997-11-05 00:00:00

abstract：STUDY OBJECTIVE:To determine the usefulness of routinely inserting a hollow airway exchange catheter (jet stylet) prior to tracheal extubation of adult patients with risk factors for difficult tracheal intubation. DESIGN:Prospective, 1-year study of 40 consecutive patients undergoing mechanical ventilation who had one...

journal_title：Chest

authors： Loudermilk EP,Hartmannsgruber M,Stoltzfus DP,Langevin PB

更新日期：1997-06-01 00:00:00

abstract：:A case of acute tuberculous pneumonia diagnosed by transbronchial biopsy is presented. We postulate that the unusually rapid progression was due to an exudative hypersensitivity reaction to aspirated tuberculoprotein. ...

journal_title：Chest

authors： Septimus EJ,Awe RJ,Greenberg SD,Raleigh JW

更新日期：1977-06-01 00:00:00

abstract：:Two-dimensional echocardiography showed myocardial thickening in 3 of 16 acute myocarditis patients in childhood. In all 3 cases, this myocardial thickening was transient and diminished within 3 weeks. This myocardial thickening was most marked at a few days after the onset; the interventricular septal thickness for e...

journal_title：Chest

authors： Nakagawa M,Hamaoka K

更新日期：1993-12-01 00:00:00

abstract：:A new bronchoscopic-protected catheter brush (BPCB), designed to obtain uncontaminated bronchial secretions, was studied in vitro and in vivo. The device was composed of a standard biopsy brush, protected by a single catheter and occluded with an agar plug. Ejection of the plug was obtained neither by advancing the br...

journal_title：Chest

authors： Marquette CH,Ramon P,Courcol R,Wallaert B,Tonnel AB,Voisin C

更新日期：1988-04-01 00:00:00

abstract：:False-negative results from transthoracic needle aspiration biopsy of malignant lung masses may occur if a central necrotic area is present and is the source of the biopsy material. The purpose of this study is to determine if the use of ultrasonic guidance can improve the sensitivity of lung needle biopsies in this c...

journal_title：Chest

authors： Pan JF,Yang PC,Chang DB,Lee YC,Kuo SH,Luh KT

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Coccidioides infections often result in chronic relapsing disease that presents a challenge to the currently available therapy. Posaconazole, an oral extended-spectrum triazole agent, has been shown in vitro and in vivo to have potent activity against this fungus. METHODS:An open-label multinational study o...

journal_title：Chest

authors： Stevens DA,Rendon A,Gaona-Flores V,Catanzaro A,Anstead GM,Pedicone L,Graybill JR

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to compare antibiotic prescribing practices and survival in the ICU for patients with pneumococcal severe community-acquired pneumonia (SCAP) between 2000 and 2013. METHODS:This was a matched case-control study of two prospectively recorded cohorts in Europe. Eighty pat...

journal_title：Chest

authors： Gattarello S,Borgatta B,Solé-Violán J,Vallés J,Vidaur L,Zaragoza R,Torres A,Rello J,Community-Acquired Pneumonia en la Unidad de Cuidados Intensivos II Study Investigators*.

更新日期：2014-07-01 00:00:00

abstract：STUDY OBJECTIVES:Pulmonary rehabilitation (PR) that includes exercise training can improve exercise tolerance and quality of life for patients with COPD. However, the degree of benefit from PR is variable. We hypothesized that the exercise response to PR varies depending on the initial factors that limit exercise. DES...

journal_title：Chest

authors： Plankeel JF,McMullen B,MacIntyre NR

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To determine the success rate and correlates of ambulatory peak expiratory flow (PEF) monitoring in an epidemiologic study. DESIGN:An observational survey. SETTING:Several communities in California. PARTICIPANTS:We studied 1,223 nonsmoking men and women (mean age, 66 years) from an established cohort. OUT...

journal_title：Chest

authors： Enright PL,Burchette RJ,Peters JA,Lebowitz MD,McDonnell WF,Abbey DE

更新日期：1997-10-01 00:00:00