Abstract:
OBJECTIVE:To determine the success rate and correlates of ambulatory peak expiratory flow (PEF) monitoring in an epidemiologic study. DESIGN:An observational survey. SETTING:Several communities in California. PARTICIPANTS:We studied 1,223 nonsmoking men and women (mean age, 66 years) from an established cohort. OUTCOME MEASURES:A standard respiratory symptoms and diagnoses questionnaire, spirometry before and after bronchodilator, and a diary of PEF recorded four times per day for 7 days at home. RESULTS:A physician diagnosis of asthma was reported in 8.6% of the women and 9.4% of the men. Of those who agreed to complete PEF diaries at home, 87% successfully provided a valid measure of PEF lability. The mean PEF lability from those with asthma was significantly higher than the others (12.0% vs 8.9% in women and 10.2% vs 8.1% in men). Independent correlates of higher PEF lability included asthma, wheezing symptoms, airways obstruction by spirometry, older age, and male gender. CONCLUSIONS:Middle-aged and elderly persons are largely successful at providing a measure of PEF lability at home. In nonsmoking adults living in California, increased PEF lability is correlated with asthma, wheezing, airways obstruction, and older age, validating its use in epidemiology studies as an index of airways hyperreactivity.
journal_name
Chestjournal_title
Chestauthors
Enright PL,Burchette RJ,Peters JA,Lebowitz MD,McDonnell WF,Abbey DEdoi
10.1378/chest.112.4.895subject
Has Abstractpub_date
1997-10-01 00:00:00pages
895-901issue
4eissn
0012-3692issn
1931-3543pii
S0012-3692(15)47267-8journal_volume
112pub_type
杂志文章相关文献
CHEST文献大全abstract:BACKGROUND:Obesity is known to be an important risk factor for OSA; however, OSA can also be seen in nonobese patients with a small maxilla and/or mandible as well as in all obese patients with such features. Thus, we hypothesized that regional factors, oropharyngeal crowding associated with fat deposition, and maxillo...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2016.03.005
更新日期:2016-08-01 00:00:00
abstract::To further delineate indications for noninvasive pressure support ventilation (NIPSV), we proposed this noninvasive technique as an alternative to endotracheal intubation in 17 consecutive patients with acute respiratory failure from various causes. Eight patients (47 percent) were successfully ventilated with NIPSV, ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.3.907
更新日期:1993-03-01 00:00:00
abstract::A 75-year-old man with a history of resected colon carcinoma presented to his primary care physician because of a new onset of coughing. The patient had expectorated a small piece of solid tissue; pathologic examination of the tissue found it to be consistent with metastatic colon adenocarcinoma. After further work-up...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.113.1.244
更新日期:1998-01-01 00:00:00
abstract::An asymptomatic young man presented with a cardiac murmur and hypertension only in the right arm. Angiograms showed kinking of the aortic arch with a figure-eight appearance consistent with pseudocoarctation. Before the kinked segment, also demonstrated were a stenotic lesion in the aortic arch proximal to the left ca...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.5.1239
更新日期:1990-05-01 00:00:00
abstract:STUDY OBJECTIVES:To assess the functional sequelae (FS) of patients with tuberculous pleurisy (TP), to analyze the influence of different factors in the occurrence of these FS, and, finally, to evaluate the relationship between the FS and roentgenographic sequelae. DESIGN:An observational, retrospective study. SETTIN...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.123.6.1996
更新日期:2003-06-01 00:00:00
abstract::The respiratory pattern during wakefulness and sleep was characterized in a 70-year-old woman with respiratory dyskinesia. During wakefulness, both respiratory frequency and tidal volume exhibited an irregularly irregular pattern. In addition, wide fluctuations occurred in the position of the rib cage and abdomen at e...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.90.5.779
更新日期:1986-11-01 00:00:00
abstract:STUDY OBJECTIVE:The diagnostic value of tumor markers in pleural fluid is subject to debate. The aim of this study was to evaluate the diagnostic performance of several tumor markers in common use for detecting malignant pleural disease. DESIGN:Blinded comparison of four tumor markers in pleural fluid with a confirmat...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.6.1757
更新日期:2004-12-01 00:00:00
abstract::Microbubble formation has been accepted as the mechanism producing contrast echoes. Comparisons of the contrast effects of various agents have been studied extensively, but the importance of gas-mixing has been less appreciated. To test the hypothesis that good gas-mixing, by facilitating microbubble formation, would ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.89.5.723
更新日期:1986-05-01 00:00:00
abstract:STUDY OBJECTIVES:We sought to compare catheter studies using a right ventricular ejection fraction (REF) catheter together with echocardiography and MRI in patients with pulmonary hypertension. PATIENTS AND METHODS:We compared hemodynamic findings, echocardiography, and MRI studies in 16 patients with pulmonary hypert...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.2.502
更新日期:2001-08-01 00:00:00
abstract::Mucociliary clearance (MCC) is one of the most important nonspecific defense mechanisms of the respiratory tract, and its impairment is a well-documented feature of chronic respiratory diseases, including asthma. In vitro and in vivo data suggest that several inflammatory mediators influence the mucociliary apparatus....
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.118.4.1142
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial pneumonia and sometimes coexists with a histologic usual interstitial pneumonia (UIP) pattern. This study aimed to describe the distinct clinical features of PPFE with UIP pattern compared with idiopathic pulmonary fibrosis (IPF). METHOD...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.13-2866
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Combination therapy with inhaled corticosteroids (ICSs) and long-acting beta(2)-agonists (LABAs), or treatment with high doses of ICSs alone improves asthma control when therapy with low-dose ICSs is not sufficient. However, it is not known which of these treatment options is more effective in sustaining ast...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1378/chest.08-1018
更新日期:2008-12-01 00:00:00
abstract::Portopulmonary hypertension (PPHTN) is an uncommon complication of advanced liver disease. Epoprostenol has been effective in the treatment of PPHTN and has been used as a bridge to orthotopic liver transplantation (OLT). The role of OLT in the reversal of PPHTN is unclear. We report a case of severe PPHTN (mean pulmo...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.5.1497
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Cough is a common symptom prompting patients to seek medical care. Like patients in the general population, patients with compromised immune systems also seek care for cough. However, it is unclear whether the causes of cough in immunocompromised patients who are deemed unlikely to have a life-threating cond...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2017.07.039
更新日期:2017-11-01 00:00:00
abstract:STUDY OBJECTIVE:s: Consensus guidelines for the empirical treatment of community-acquired pneumonia (CAP) have been published. We investigated the following factors: (1) the degree of adherence to American Thoracic Society (ATS) and the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) guidelines; and (2) the...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.2.612
更新日期:2002-08-01 00:00:00
abstract::An asymptomatic cremator was found incidentally to have lymphocytic alveolitis by bronchoalveolar lavage, and the basis for this finding was investigated. No known causes of lymphocyte alveolitis including sarcoidosis, hypersensitivity pneumonitis, berylliosis, tuberculosis, or fungal diseases of the lung were found. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.105.2.617
更新日期:1994-02-01 00:00:00
abstract::Urticaria with systemic effects occurred in a patient being treated with propranolol and was reproducible upon rechallenge with the drug; Successful beta-adrenergic blocking therapy was achieved using a new agent, tolamolol, with no evidence of any adverse effects. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.67.4.496
更新日期:1975-04-01 00:00:00
abstract:OBJECTIVE:An overdiagnosis bias occurs with the diagnosis of a disease that does not produce signs or symptoms before the patient dies from other causes. We sought to determine whether overdiagnosis bias is a factor when screening for squamous cell carcinoma of the lung. DESIGN:Retrospective study of the Miyagi Popula...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.1.108
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Among patients hospitalized for community-acquired pneumonia (CAP), the risk factors for short-term hospital readmission after discharge are unknown. METHODS:We conducted a prospective observational study of 1,117 patients who had been discharged alive after hospitalization for CAP. We collected variables a...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.08-2950
更新日期:2009-10-01 00:00:00
abstract::Hyperbaric oxygen therapy, the administration of 100% oxygen at pressures > 1 atm, is believed to promote wound healing by increasing angiogenesis and collagen synthesis. To our knowledge, this treatment modality has never been described in patients with tracheal radionecrosis. Here, we report the case of a 55-year-ol...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2016.03.027
更新日期:2016-12-01 00:00:00
abstract::To elucidate the effect of oxitropium bromide (OTB), an anticholinergic drug, on dyspnea and gas exchange during exercise in patients with chronic obstructive pulmonary disease (COPD), we performed the cycle exercise test on 19 patients with COPD (mean age, 72.0 +/- 1.9 years; mean FEV1, 1.28 +/- 0.07 L) before and af...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.103.6.1774
更新日期:1993-06-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the extent to which rapid on-site cytologic evaluation (ROSE) of transbronchial needle aspiration (TBNA) samples can safely and cost-effectively reduce the need for additional biopsy during bronchoscopy. SETTING:University Hospital in Long Island, NY. PATIENT AND METHODS:Forty-four bronch...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.2.869
更新日期:2005-08-01 00:00:00
abstract::Thromboendarterectomy is the treatment of choice for chronic large vessel thromboembolic pulmonary hypertension. To identify the mechanisms responsible for the improvement in gas exchange following thromboendarterectomy, we studied nine patients with chronic thromboembolic pulmonary hypertension before and eight to 18...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.1.14
更新日期:1990-07-01 00:00:00
abstract:PURPOSE:The National Asthma Education and Prevention Program (NAEPP) published guidelines for asthma management in 1991. The purpose of this study is to assess the concordance between emergency physicians' practice and the guidelines. DESIGN:Survey mailed to emergency physicians. Non-respondents were mailed a second c...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.109.3.708
更新日期:1996-03-01 00:00:00
abstract::A series of 15 patients with life threatening, massive hemoptysis is reported. Thirteen of these patients underwent immediate operative treatment with only three deaths. One died after bronchoscopic identification of the bleeding site while awaiting elective thoracotomy. The other patient left the hospital against med...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.67.2.152
更新日期:1975-02-01 00:00:00
abstract::Rupture of the left ventricular free wall after acute myocardial infarction (AMI) has been regarded as uniformly fatal unless emergency surgical repair is performed. Among 2,862 patients admitted with AMI to our ICU during the last 8 years, 107 patients developed rupture of the left ventricular free wall. Twenty-nine ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.109.2.565
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVES:To gain more knowledge of changes in main pulmonary artery flow and right ventricular mass and volumes in patients with pulmonary hypertension during epoprostenol therapy. METHODS:Eleven patients (9 women) were evaluated before the start of therapy and every 4 months thereafter. Right and left ventricular v...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.2.572
更新日期:2004-02-01 00:00:00
abstract::The objective was to determine if garnetting and raw cotton dusts differed in botanical composition. Estimates of dust composition were based on the contents of gross trash in cotton raw materials and the potential of each gross trash component to be converted into less than 10 mum particulate by a laboratory abrasion...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.79.4_supplement.97s
更新日期:1981-04-01 00:00:00
abstract::The adverse effects of prolonged immobility are due primarily to gravitational effects on blood flow and ventilation, impairment of the normal mucociliary escalator and possibly an increase in extravascular lung water. However, CLRT theoretically should reverse these abnormalities. The sequence of events that culminat...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.1378/chest.99.5.1263
更新日期:1991-05-01 00:00:00
abstract:STUDY OBJECTIVES:The aim of this study was to explore the relationship between quality of life and measures of asthma, such as lung function, reversibility to bronchodilation, exhaled nitric oxide (NO), and bronchial responsiveness to direct and indirect stimulus in patients with mild asthma in a primary care setting. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.129.3.624
更新日期:2006-03-01 00:00:00