Oral Low-dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients With Severe COPD: A Pilot Clinical Trial.

abstract：OBJECTIVE:Congenital airway malacia is one of the few causes of irreversible airways obstruction in children, but the incidence in the general population is unknown. Severe airway malacia or malacia associated with specific syndromes is usually recognized and diagnosed early in infancy, but information about clinical f...

journal_title：Chest

authors： Boogaard R,Huijsmans SH,Pijnenburg MW,Tiddens HA,de Jongste JC,Merkus PJ

更新日期：2005-11-01 00:00:00

abstract：STUDY OBJECTIVE:To ascertain the incidence, types, morbidity, and mortality of infectious episodes in isolated lung transplant recipients. DESIGN:Retrospective chart review of patients who have undergone transplants over a six-year period in one institution. PATIENTS:Twenty-three single and 17 double lung transplants...

journal_title：Chest

authors： Maurer JR,Tullis DE,Grossman RF,Vellend H,Winton TL,Patterson GA

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Interest in airways inflammatory disease has increasingly focused on innate immunity. We investigated several components of innate immunity in induced sputum of patients with cystic fibrosis (CF), COPD, and asthma, and healthy control subjects. METHODS:Twenty eight patients with mild CF lung disease (age > ...

journal_title：Chest

authors： Xiao W,Hsu YP,Ishizaka A,Kirikae T,Moss RB

更新日期：2005-10-01 00:00:00

abstract：:Positron emission tomography (PET) imaging is an important tool to refine the diagnosis and staging approach in patients with a possible lung cancer. In addition, other applications of PET imaging are being explored. Data consistently show that the intensity of uptake on a PET scan correlates with the biological aggre...

journal_title：Chest

authors： Detterbeck FC,Vansteenkiste JF,Morris DE,Dooms CA,Khandani AH,Socinski MA

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Failure to reliably diagnose ARDS may be a major driver of negative clinical trials and underrecognition and treatment in clinical practice. We sought to examine the interobserver reliability of the Berlin ARDS definition and examine strategies for improving the reliability of ARDS diagnosis. METHODS:Two hu...

journal_title：Chest

authors： Sjoding MW,Hofer TP,Co I,Courey A,Cooke CR,Iwashyna TJ

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:To review statistics on smoking prevalence and to analyze whether the implementation of national tobacco control legislation had an association with the prevalence of smoking, and thereby, with the occurrence of smoking-related lung diseases. DESIGN:Smoking prevalence rates (from 1960 to 2000), lung cancer ...

journal_title：Chest

authors： Heloma A,Nurminen M,Reijula K,Rantanen J

更新日期：2004-12-01 00:00:00

abstract：:The literature on pulmonary function testing in sarcoidosis is critically reviewed. The results indicate that pulmonary function tests are not a reliable means for detecting the presence of parenchymal sarcoidosis, nor do they provide an accurate estimate of the extent of parenchymal disease. There are at present no k...

journal_title：Chest

authors： Winterbauer RH,Hutchinson JF

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:There is a growing use of procalcitonin (PCT) to facilitate the diagnosis and management of severe sepsis. We investigated the impact of one to two PCT determinations on ICU day 1 on health-care utilization and cost in a large research database. METHODS:A retrospective, propensity score-matched multivariabl...

journal_title：Chest

authors： Balk RA,Kadri SS,Cao Z,Robinson SB,Lipkin C,Bozzette SA

更新日期：2017-01-01 00:00:00

abstract：STUDY OBJECTIVES:The purpose of this study was to determine the impact of a multisite implementation of an evidence-based clinical practice guideline for bronchiolitis. DESIGN:Before and after study. SETTING:Eleven Child Health Accountability Initiative (CHAI) study hospitals. PATIENTS:Children < 12 months of age wi...

journal_title：Chest

authors： Kotagal UR,Robbins JM,Kini NM,Schoettker PJ,Atherton HD,Kirschbaum MS

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:To determine whether certain occupations and occupationally related exposures were associated with a history of sarcoidosis in African-American siblings. METHODS:We collected occupational data from 921 African Americans in 273 sibships that had been identified through a sarcoidosis case. Among the 648 sibli...

journal_title：Chest

authors： Kucera GP,Rybicki BA,Kirkey KL,Coon SW,Major ML,Maliarik MJ,Iannuzzi MC

更新日期：2003-05-01 00:00:00

abstract：:Pulmonary hypertension is a common finding in patients with idiopathic pulmonary fibrosis (IPF), and is associated with increased morbidity and mortality. Therapy with sildenafil has been shown to decrease pulmonary vascular resistance in patients with pulmonary fibrosis and may improve functional status. Patients wit...

journal_title：Chest

authors： Collard HR,Anstrom KJ,Schwarz MI,Zisman DA

更新日期：2007-03-01 00:00:00

abstract：:In a prospective study murmurs increased in intensity with carotid sinus pressure in 18 of 26 patients with hypertrophic obstructive cardiomyopathy (HOCM) (sensitivity, 69.2 percent for the 26 patients, 85.7 percent for the 21 patients in whom heart rate and blood pressure decreased with carotid sinus pressure). On th...

journal_title：Chest

authors： Klein HO,DiSegni E,Dean H,Beker B,Bakst A,Kaplinsky E

更新日期：1988-04-01 00:00:00

abstract：:A growing number of drugs, including a number of alkylating agents, have been implicated as the cause of pulmonary diseases. A patient with chronic myelogenous leukemia presented with typical cytology, biopsy, and roentgenologic findings of lung toxicity after only six weeks of therapy with busulfan. There was subsequ...

journal_title：Chest

authors： Hankins DG,Sanders S,MacDonald FM,Drage CW

更新日期：1978-03-01 00:00:00

abstract：:In a 52-year-old man, chronic eosinophilic pneumonia (CEP), suggested by clinical history and marked eosinophilia in the peripheral blood and in the bronchoalveolar lavage fluid, has been diagnosed on open lung biopsy. Nevertheless, chest roentgenograms never showed any infiltration during the course of the disease. E...

journal_title：Chest

authors： Dejaegher P,Derveaux L,Dubois P,Demedts M

更新日期：1983-11-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the accuracy of the respiratory inductive plethysmography in the measurement of PEEP-induced changes in end-expiratory lung volume during mechanical ventilation and its accuracy and stability in the measurement of ventilation during controlled mechanical ventilation and spontaneous breathing. ...

journal_title：Chest

authors： Valta P,Takala J,Foster R,Weissman C,Kinney JM

更新日期：1992-07-01 00:00:00

abstract：:Coronary bypass patients less than 40 years of age were identified and compared with a control group previously studied at our hospital. In patients less than 40 years, the average age was 35 years. Men comprised 90.1 percent of group 1, and 83.4 percent of group 2. Operative mortality was 2.89 percent for group 1 and...

journal_title：Chest

authors： Kelly ME,DeLaria GA,Najafi H

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Cytochrome P-450 2J2 (CYP2J2) has recently been shown to be an important enzyme in the metabolism of epoxygenase-derived eicosanoids that play important functional roles in pulmonary physiology and may contribute to the pathogenesis of asthma. STUDY OBJECTIVE:The focus of our pilot study was to evaluate whe...

journal_title：Chest

authors： Polonikov AV,Ivanov VP,Solodilova MA,Khoroshaya IV,Kozhuhov MA,Panfilov VI

更新日期：2007-07-01 00:00:00

abstract：:Eighteen postmenopausal women were examined by Doppler echocardiography before initiation of HRT (T1), then after ten weeks (T2) and one year (T3). This study group was compared with another in which HRT was not used. Flow velocity integral, which correlates with SV, and MA, an indicator of cardiac contractility, were...

journal_title：Chest

authors： Pines A,Fisman EZ,Ayalon D,Drory Y,Averbuch M,Levo Y

更新日期：1992-11-01 00:00:00

abstract：PURPOSE:To assess whether the presence and duration of air leaks after lobectomy are associated with an increased incidence of cardiopulmonary complications. METHODS:Propensity score analysis was used on 726 patients undergoing pulmonary lobectomy from 1995 through 2004 to form three well-matched pairs of patients: pa...

journal_title：Chest

authors： Brunelli A,Xiume F,Al Refai M,Salati M,Marasco R,Sabbatini A

更新日期：2006-10-01 00:00:00

abstract：:Primary pulmonary hypertension (PPH) is a serious pulmonary vascular disease occurring mostly in adult women. Although its occurrence in families was reported within a few years after the original clinical report, PPH was formerly believed rarely to have a genetic basis. Recent progress has not only clarified a basic ...

journal_title：Chest

authors： Loyd JE

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Recent study of the inflammatory reactions occurring during and after cardiopulmonary bypass (CPB) has improved our understanding of the involvement of the inflammatory cascade in perioperative injury. However, the exact mechanisms of this complex response remain to be fully determined. METHODS:Literature o...

journal_title：Chest

authors： Wan S,LeClerc JL,Vincent JL

更新日期：1997-09-01 00:00:00

abstract：:Hydrochlorothiazide (HCTZ)-induced pulmonary disease has been described as either an allergic interstitial pneumonitis or a cause of noncardiogenic pulmonary edema. The mechanism of this rare life-threatening side effect is largely unknown. Many patients show peripheral leukopenia and extensive immunologic studies rev...

journal_title：Chest

authors： Darwish OS,Criley J

更新日期：2011-01-01 00:00:00

abstract：:This study investigated the effect of dynamic exercise on mitral regurgitation (MR) as assessed by color flow Doppler imaging and tested the hypothesis that MR increases in patients with left ventricular (LV) function worsening during exercise. We studied 513 patients (390 men, 123 women:mean age [+/-1 SD] 58+/-11 yea...

journal_title：Chest

authors： Peteiro J,Freire E,Montserrat L,Castro-Beiras A

更新日期：1998-10-01 00:00:00

abstract：:Ventilation and gas exchange were studied during sleep and incremental treadmill exercise in 19 patients with severe stable COPD with the primary aim of comparing the pathophysiology of oxygen desaturation in the two conditions. A secondary aim was to determine whether exercise studies could aid in the prediction of s...

journal_title：Chest

authors： Mulloy E,McNicholas WT

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:The implementation of workplace smoking bans has contributed to a significant reduction in the incidence of acute coronary syndrome admissions, but their influence on adult acute pulmonary disease admissions is unclear. We sought to assess the impact of a national smoking ban on nationwide admissions of indi...

journal_title：Chest

authors： Kent BD,Sulaiman I,Nicholson TT,Lane SJ,Moloney ED

更新日期：2012-09-01 00:00:00

abstract：STUDY OBJECTIVES:To describe the risk factors for the development of and mortality resulting from acute respiratory failure (ARF) in a large patient population. DESIGN:A substudy of a prospective, multicenter, observational cohort study, which was designed to validate the sequential organ failure assessment score. SE...

journal_title：Chest

authors： Vincent JL,Akça S,De Mendonça A,Haji-Michael P,Sprung C,Moreno R,Antonelli M,Suter PM,SOFA Working Group. Sequntial organ failure assessment.

更新日期：2002-05-01 00:00:00

abstract：:Five different volumes of test solutions (1 to 3 ml) containing 15 mg of metaproterenol were placed in each of five different nebulizers. The time to complete nebulization and the amount of drug delivered varied considerably, depending upon the initial volume of solution placed in the nebulizer. Small volumes (1 ml) w...

journal_title：Chest

authors： Kradjan WA,Lakshminarayan S

更新日期：1985-04-01 00:00:00

abstract：:A case of subaortic stenosis caused by two discrete membranes is presented. Following demonstration of the two distinct sites of obstruction by intraventricular pressure gradients and angiocardiogram, the two membranes were excised through a transaortic approach. The importance of being aware of the occurrence of this...

journal_title：Chest

authors： Lemole GM,Tesler UF,Colombi M,Eldredge WJ

更新日期：1976-01-01 00:00:00

abstract：:Results of preoperative pulmonary function tests were evaluated in 106 patients who had major thoracic or upper abdominal cardiovascular surgery. These results were related to the occurrence of postoperative complications by comparison of pulmonary function data in patients with an ICU stay of less than 5 days versus ...

journal_title：Chest

authors： Cain HD,Stevens PM,Adaniya R

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Lidocaine is used to alleviate procedural pain but paradoxically increases pain during injection. Pain perception can be modulated by non-noxious stimuli such as temperature or touch according to the gate control theory of pain. We postulated that lidocaine dripped onto the skin prior to injection would cool...

journal_title：Chest

authors： Patel BK,Wendlandt BN,Wolfe KS,Patel SB,Doman ER,Pohlman AS,Hall JB,Kress JP

更新日期：2018-10-01 00:00:00