Posaconazole therapy for chronic refractory coccidioidomycosis.

abstract：BACKGROUND:Proton pump inhibitors (PPIs) and histamine type 2 receptor blockers (H2Bs) are used for stress ulcer prophylaxis. Although the PPIs have greater potency for acid suppression, their relative effectiveness for preventing clinically important GI bleeding (CIGIB) has not been established. The goal of this study...

journal_title：Chest

authors： Lilly CM,Aljawadi M,Badawi O,Onukwugha E,Tom SE,Magder LS,Harris I

更新日期：2018-09-01 00:00:00

abstract：:Transient left ventricular (LV) dysfunction syndrome, or Tako-tsubo syndrome, occurs following intense emotional or physical stress and simulates the clinical presentation of an acute myocardial infarction. We report a case of a 77-year-old man with esophageal adenocarcinoma with local invasion of the central airways ...

journal_title：Chest

authors： Guerrero J,Majid A,Ernst A

更新日期：2009-01-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually fatal disease, based on a multifaceted and incompletely understood pathogenesis. Some of the cellular and molecular mechanisms of vascular remodeling have been experimentally explored, and it is obvious that alterations of microvessels are invo...

journal_title：Chest

authors： Hanumegowda C,Farkas L,Kolb M

更新日期：2012-07-01 00:00:00

abstract：:A case of acute and recrudescent melioidosis complicated by pericarditis and pericardial effusion is described. The potential for the appearance of future cases in the United States and the necessity for physicians to remain aware of this potential diagnosis are discussed. ...

journal_title：Chest

authors： Ruff MJ,Lamkin N Jr,Braun J,Barnwell P

更新日期：1976-02-01 00:00:00

abstract：:Acute hypoxemic respiratory failure (AHRF) can result from diverse lung insults. Toxic oxygen metabolites have been implicated in this clinical condition and in animal models of pulmonary edema. Hydrogen peroxide (H2O2), an oxygen metabolite, mediates tissue injury. We measured H2O2 levels by a spectrophotometric tech...

journal_title：Chest

authors： Sznajder JI,Fraiman A,Hall JB,Sanders W,Schmidt G,Crawford G,Nahum A,Factor P,Wood LD

更新日期：1989-09-01 00:00:00

abstract：:We retrospectively studied the acute toxicity of corticosteroid therapy in 23 episodes of PCP occurring in the setting of AIDS and determined the incidence of HIV-related complications following these and 16 other contemporaneous episodes of AIDS-related PCP treated with antimicrobials alone. The mean duration of cort...

journal_title：Chest

authors： Lambertus MW,Goetz MB,Murthy AR,Mathisen GE

更新日期：1990-07-01 00:00:00

abstract：:A 34-year-old HIV-infected man was successfully treated with antimicrobial therapy alone for Rhodococcus equi pneumonia and has survived longer than six months. In the current literature, only two of seven HIV-infected patients so treated have survived as long as six months. Based on our experience and the available l...

journal_title：Chest

authors： Cury JD,Harrington PT,Hosein IK

更新日期：1992-11-01 00:00:00

abstract：:As an aid in the differential diagnosis of exudative pleural effusions, tumor markers were investigated. We measured immunosuppressive acidic protein (IAP), carbohydrate antigen 19-9 (CA 19-9), tissue polypeptide antigen (TPA), carcinoembryonic antigen (CEA), adenosine deaminase (ADA), and alpha 1-acid glycoprotein (A...

journal_title：Chest

authors： Niwa Y,Kishimoto H,Shimokata K

更新日期：1985-03-01 00:00:00

abstract：:Antiphospholipid syndrome is an autoimmune disorder characterized by a hypercoagulable state, leading to arterial and venous thrombosis. We present a 23-year-old patient, suspected of having Budd-Chiari syndrome due to antiphospholipid syndrome, who developed severe and progressive hypoxemia, requiring prolonged mecha...

journal_title：Chest

authors： Bunge JJH,Wiersema US,Moelker A,van Bommel J,Tjwa ETTL

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The benefits of inhaled corticosteroids in the management of COPD are less apparent than they are in asthma therapy, and the potential for adverse systemic effects of high-dose inhaled corticosteroids has been recognized recently. It is therefore essential to know the maximal obtainable benefits in order to ...

journal_title：Chest

authors： Nishimura K,Koyama H,Ikeda A,Tsukino M,Hajiro T,Mishima M,Izumi T

更新日期：1999-01-01 00:00:00

abstract：:Fondaparinux, a selective inhibitor of factor Xa, is the first of a new class of antithrombotic compounds, the synthetic pentasaccharides. Its benefit-to-risk ratio in preventing venous thromboembolism after major orthopedic surgery was investigated in four randomized, double-blind international phase III trials in pa...

journal_title：Chest

authors： Turpie AG,Eriksson BI,Bauer KA,Lassen MR

更新日期：2003-12-01 00:00:00

abstract：STUDY OBJECTIVES:The objective of this study was to evaluate the feasibility of the sentinel lymph node (SLN) biopsy in peripheral clinically stage I or II non-small cell lung cancer (NSCLC) using (99m)Tc colloid and a hand-held gamma detection probe, associated with a blue dye technique. DESIGN:Prospective study. SE...

journal_title：Chest

authors： Tiffet O,Nicholson AG,Khaddage A,Prévot N,Ladas G,Dubois F,Goldstraw P

更新日期：2005-02-01 00:00:00

abstract：:We describe a case of unsuspected infrahepatic interruption of the inferior vena cava with hemiazygos continuation in a 67-year-old man presenting with chest pain and evidence of mitral regurgitation. He had no persistent superior vena cava, with the hemiazygos draining directly into the right superior vena cava. Poly...

journal_title：Chest

authors： Dellavalle A,Ribichini F,Steffenino G

更新日期：1994-11-01 00:00:00

abstract：:Clinical trials have established the superiority of the implantable cardioverter-defibrillator (ICD) over antiarrhythmic drug therapy in survivors of sudden cardiac death and in high-risk patients with coronary artery disease. The ICD has evolved to overcome the limitation of earlier devices that required thoracotomy ...

journal_title：Chest

authors： Gollob MH,Seger JJ

更新日期：2001-04-01 00:00:00

abstract：:Chemical sclerosis of the pleural space is used to prevent recurrence of spontaneous pneumothorax. To test whether sclerosis restricts diaphragmatic excursion, we measured diaphragmatic excursion by ultrasonography in subjects with unilateral pleural sclerosis and compared it with diaphragmatic excursions in normal su...

journal_title：Chest

authors： Loring SH,Kurachek SC,Wohl ME

更新日期：1989-02-01 00:00:00

abstract：INTRODUCTION:The specific causes and mechanism(s) for asthma occurring among occupants of non-residential buildings with poor indoor air quality are not known, but allergic and nonallergic processes are possible explanations METHODS:Repeated indoor air quality measurements were made while employees were working in a b...

journal_title：Chest

authors： Brooks SM,Spaul W,McCluskey JD

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Septic pulmonary embolism (SPE) is an uncommon disorder with an insidious onset and is difficult to diagnose. STUDY OBJECTIVES:To characterize the presenting features and clinical course of patients with SPE. DESIGN:Retrospective study. SETTING:Tertiary care, referral medical center. PATIENTS:Fourteen su...

journal_title：Chest

authors： Cook RJ,Ashton RW,Aughenbaugh GL,Ryu JH

更新日期：2005-07-01 00:00:00

abstract：:Positron emission tomography (PET) imaging is an important tool to refine the diagnosis and staging approach in patients with a possible lung cancer. In addition, other applications of PET imaging are being explored. Data consistently show that the intensity of uptake on a PET scan correlates with the biological aggre...

journal_title：Chest

authors： Detterbeck FC,Vansteenkiste JF,Morris DE,Dooms CA,Khandani AH,Socinski MA

更新日期：2004-11-01 00:00:00

abstract：:The usefulness of lung-thorax compliance (or elastance) as an index of pulmonary compliance (or elastance) was examined in 15 patients being ventilated for acute respiratory failure. Mean lung-thorax elastance (ELT) was 27.9 +/- 2.6 cm H2O/L, and the chest wall accounted for 34 +/- 2 percent of the mean total value. C...

journal_title：Chest

authors： Katz JA,Zinn SE,Ozanne GM,Fairley HB

更新日期：1981-09-01 00:00:00

abstract：:Pulmonary tumor embolism is a rare but well-documented cause of respiratory failure in patients with cancer. This entity is probably clinically underrecognized and may represent an important cause of morbidity and mortality. A typical pattern of multiple peripheral subsegmental defects on perfusion lung scanning has b...

journal_title：Chest

authors： Moores LK,Burrell LM,Morse RW,Belgrave CH,Balingit AG

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:In patients with advanced non-small cell lung cancer (NSCLC) treated with chemotherapy, we compared survival in patients with treated central airway obstruction to those who did not have central airway obstruction. METHODS:One hundred forty-four patients with advanced and inoperable NSCLC were included. Thes...

journal_title：Chest

authors： Chhajed PN,Baty F,Pless M,Somandin S,Tamm M,Brutsche MH

更新日期：2006-12-01 00:00:00

abstract：:Bronchial responsiveness assessed by histamine bronchial challenge testing in 22 children with chronic stable asthma was compared with the number of inflammatory cells per milliliter of broncholavage fluid obtained by fiberoptic bronchoscopy. Hyperresponsiveness was closely correlated with increased counts of eosinoph...

journal_title：Chest

authors： Ferguson AC,Wong FW

更新日期：1989-11-01 00:00:00

abstract：:Chronic heart failure (CHF) is a complex syndrome affecting many body systems. Body wasting (ie, cardiac cachexia) is a serious complication of CHF long known but little investigated. Although no specific diagnostic criteria have been established, we have suggested that cardiac cachexia be defined on the basis of the ...

journal_title：Chest

authors： Anker SD,Coats AJ

更新日期：1999-03-01 00:00:00

abstract：:The ability of mixed venous oxygen saturation (SvO2) monitoring to reflect changes in cardiac index (CI) with therapy in critically ill patients is unclear. To this end, SvO2 and CI were measured before and during an infusion of enoximone and/or dobutamine in 30 patients with advanced heart failure. A nonlinear relati...

journal_title：Chest

authors： Jain A,Shroff SG,Janicki JS,Reddy HK,Weber KT

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in patients with COPD. METHODS:Serum SIRT1 protein of all samples was meas...

journal_title：Chest

authors： Yanagisawa S,Papaioannou AI,Papaporfyriou A,Baker JR,Vuppusetty C,Loukides S,Barnes PJ,Ito K

更新日期：2017-08-01 00:00:00

abstract：STUDY OBJECTIVE:The primary objective of this study was to test whether an elevated systolic pulmonary artery (PA) pressure or an elevated pulmonary dead space fraction (Vd/Vt) in early acute lung injury (ALI) is associated with poor clinical outcomes in the era of lung-protective ventilation. DESIGN:Prospective obser...

journal_title：Chest

authors： Cepkova M,Kapur V,Ren X,Quinn T,Zhuo H,Foster E,Liu KD,Matthay MA

更新日期：2007-09-01 00:00:00

abstract：:Thrombocytopenia is a common problem in cardiovascular patients, but the etiology and management of this condition may be different than those in other populations. Around the time that percutaneous coronary interventions are performed, the drugs most commonly associated with thrombocytopenia are the glycoprotein (GP)...

journal_title：Chest

authors： Matthai WH Jr

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Rhinovirus (RV)-induced pulmonary exacerbations are common in cystic fibrosis (CF) and have been associated with impaired virus clearance by the CF airway epithelium in vitro. Here, we assess in vivo the association of RV prevalence and load with antiviral defense mechanisms, airway inflammation, and lung fu...

journal_title：Chest

authors： Kieninger E,Singer F,Tapparel C,Alves MP,Latzin P,Tan HL,Bossley C,Casaulta C,Bush A,Davies JC,Kaiser L,Regamey N

更新日期：2013-03-01 00:00:00

abstract：:The effect of interstitial pulmonary fibrosis on pregnancy is unclear. We present the findings in a 31-year-old woman with severe pulmonary fibrosis (vital capacity, 37 percent of predicted) secondary to hard metal disease who went through a successful term pregnancy. The patient was a grinder of tungsten-carbide dril...

journal_title：Chest

authors： Ratto D,Balmes J,Boylen T,Sharma OP

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Health-care workers are concerned about the risk of acquiring contagious diseases such as severe acute respiratory syndrome and avian influenza after recent outbreaks. We studied exhaled air and particle dispersion through an oronasal mask attached to a human-patient simulator (HPS) during noninvasive positi...

journal_title：Chest

authors： Hui DS,Hall SD,Chan MT,Chow BK,Tsou JY,Joynt GM,Sullivan CE,Sung JJ

更新日期：2006-09-01 00:00:00