Angiogenesis in pulmonary fibrosis: too much or not enough?

abstract：RATIONALE:Following collapse of the World Trade Center (WTC), individuals reported new-onset respiratory symptoms. Despite symptoms, spirometry often revealed normal airway function. However, bronchial wall thickening and air trapping were seen radiographically in some subjects. We hypothesized that symptomatic individ...

journal_title：Chest

authors： Oppenheimer BW,Goldring RM,Herberg ME,Hofer IS,Reyfman PA,Liautaud S,Rom WN,Reibman J,Berger KI

更新日期：2007-10-01 00:00:00

abstract：:The diaphragm is the primary muscle of inspiration. Its capacity to respond to the load imposed by pulmonary disease is a major determining factor both in the onset of ventilatory failure and in the ability to successfully separate patients from ventilator support. It has recently been established that a very large pr...

journal_title：Chest

authors： Petrof BJ

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:Clinical practice guidelines have been devised to change practitioner performance and to improve the process and outcomes of care. The objective of this study was to determine whether adherence to a practice guideline on noninvasive positive-pressure ventilation (NPPV) for the treatment of patients with acut...

journal_title：Chest

authors： Sinuff T,Cook DJ,Randall J,Allen CJ

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:In chronic obstructive pulmonary disease, both smaller and larger airways are affected. FEV1 mainly reflects large airways obstruction, while the later fraction of forced exhalation reflects reduction in terminal expiratory flow. In this study, the objective was to evaluate the relationship between spirometr...

journal_title：Chest

authors： Dilektasli AG,Porszasz J,Casaburi R,Stringer WW,Bhatt SP,Pak Y,Rossiter HB,Washko G,Castaldi PJ,Estepar RSJ,Hansen JE,COPDGene investigators.

更新日期：2016-11-01 00:00:00

abstract：:The effect of interstitial pulmonary fibrosis on pregnancy is unclear. We present the findings in a 31-year-old woman with severe pulmonary fibrosis (vital capacity, 37 percent of predicted) secondary to hard metal disease who went through a successful term pregnancy. The patient was a grinder of tungsten-carbide dril...

journal_title：Chest

authors： Ratto D,Balmes J,Boylen T,Sharma OP

更新日期：1988-03-01 00:00:00

abstract：:Aortopulmonary window is a rare congenital cardiac anomaly. When it coexists with a ventricular septal defect, the accurate diagnosis of aortopulmonary window on the basis of clinical examination is difficult. We report the case of an infant who had an aortopulmonary window together with a ventricular septal defect. A...

journal_title：Chest

authors： Horimi H,Hasegawa T,Shiraishi H,Endo H,Yanagisawa M

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy, permanence, and safety of thoracoscopic talc poudrage (TTP) for pleurodesis in malignant effusions. DESIGN:Retrospective. PARTICIPANTS:Patients with lifetime follow-up who received TTP in two related centers in Marseilles, France. RESULTS:Three hundred sixty patients were included i...

journal_title：Chest

authors： Viallat JR,Rey F,Astoul P,Boutin C

更新日期：1996-12-01 00:00:00

abstract：:The solitary pulmonary nodule (SPN) is frequently encountered on chest imaging and poses an important diagnostic challenge to clinicians. The differential diagnosis is broad, ranging from benign granulomata and infectious processes to malignancy. Important concepts in the evaluation of SPNs include the definition, mor...

journal_title：Chest

authors： Patel VK,Naik SK,Naidich DP,Travis WD,Weingarten JA,Lazzaro R,Gutterman DD,Wentowski C,Grosu HB,Raoof S

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Spontaneous pneumothorax (SPTX) is an uncommon phenomenon in the general population and is most commonly associated with prior bulbous emphysema, cystic parenchymal lung disease, and tuberculous lung disease. A rare cause of SPTX is malignant disease, either in the form of primary lung or pleural cancers, or...

journal_title：Chest

authors： Hoag JB,Sherman M,Fasihuddin Q,Lund ME

更新日期：2010-09-01 00:00:00

abstract：:There is a small population of peripheral T cells bearing the gamma delta T-cell receptor, which may be involved in the defense against invading microorganisms and tumor cells. The present study was designed to evaluate the levels of gamma delta T cells in patients with pulmonary tuberculosis, bacterial pneumonia, chr...

journal_title：Chest

authors： Ito M,Kojiro N,Ikeda T,Ito T,Funada J,Kokubu T

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVES:This study was designed to determine the incidence rate, define risk factors, and suggest proper management protocols for pulmonary artery (PA) rupture associated with Swan-Ganz catheters. DESIGN:This is a retrospective chart-review study. SETTING:This study involved 32,442 inpatients requiring hemodynamic...

journal_title：Chest

authors： Kearney TJ,Shabot MM

更新日期：1995-11-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the safety and efficacy of sitaxsentan, an endothelin-A receptor antagonist, in a 12-week, open-label trial of patients with pulmonary arterial hypertension (PAH). PATIENTS:Six children and 14 adults with New York Heart Association (NYHA) functional class II, III, or IV primary pulmonary h...

journal_title：Chest

authors： Barst RJ,Rich S,Widlitz A,Horn EM,McLaughlin V,McFarlin J

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To assess the effect of baseline variables, including treatment, on outcome in patients with nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA). DESIGN:Retrospective analysis of data from two prospective, randomized, double-blind studies. SETTING:Multinational study with 134 site...

journal_title：Chest

authors： Wunderink RG,Rello J,Cammarata SK,Croos-Dabrera RV,Kollef MH

更新日期：2003-11-01 00:00:00

abstract：:Fluid infusion may be lifesaving in patients with severe sepsis, especially in the earliest phases of treatment. Following initial resuscitation, however, fluid boluses often fail to augment perfusion and may be harmful. In this review, we seek to compare and contrast the impact of fluids in early and later sepsis; sh...

journal_title：Chest

authors： Durairaj L,Schmidt GA

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:During noninvasive ventilation, nonintentional leaks have a detrimental effect on the efficacy of ventilation. A wide range of industrial masks are available, with intentional leaks of different importance. The potential impact of this variability in intentional leaks on performances of bilevel ventilators h...

journal_title：Chest

authors： Borel JC,Sabil A,Janssens JP,Couteau M,Boulon L,Lévy P,Pépin JL

更新日期：2009-03-01 00:00:00

abstract：STUDY OBJECTIVES:Among adults presenting to the emergency department (ED) with acute asthma, we sought to determine the prevalence of obesity, and the relation of body mass index (BMI) to asthma severity in this high-risk population. DESIGN:Multicenter, prospective cohort study. SETTING:Twenty-six North American EDs....

journal_title：Chest

authors： Thomson CC,Clark S,Camargo CA Jr,MARC Investigators.

更新日期：2003-09-01 00:00:00

abstract：:Superior vena caval (SVC) syndrome may be caused by extravascular compression or intravascular obstruction. Knowing the mechanism of SVC syndrome enables the physician to choose appropriate treatment. Transesophageal echocardiography (TEE) is a safe bedside procedure that is excellent for evaluating the SVC and its su...

journal_title：Chest

authors： Ayala K,Chandrasekaran K,Karalis DG,Parris TM,Ross JJ Jr

更新日期：1992-03-01 00:00:00

abstract：STUDY OBJECTIVES:The inhalation of hypoxic gas has been reported to enhance the airway responsiveness to methacholine in some animal models. However, the data on humans have so far been conflicting. We attempted to examine the effect of hypoxic gas inhalation on the airway responsiveness to methacholine. DESIGN:We eva...

journal_title：Chest

authors： Saito H,Nishimura M,Shinano H,Sato F,Miyamoto K,Kawakami Y

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:We investigated factors related to the diagnostic sensitivity of CT-guided transbronchial biopsy (TBB) using an ultrathin bronchoscope and virtual bronchoscopy (VB) navigation for small peripheral pulmonary lesions. METHOD:We have performed this procedure on 83 patients with 85 small peripheral pulmonary le...

journal_title：Chest

authors： Shinagawa N,Yamazaki K,Onodera Y,Asahina H,Kikuchi E,Asano F,Miyasaka K,Nishimura M

更新日期：2007-02-01 00:00:00

abstract：:Norepinephrine, an alpha 1,2-beta 1,2-adrenergic agonist, seems to be an alternative to epinephrine, an alpha 1,2-beta 1,2-agonist, for restoration of spontaneous circulation in VF. We therefore studied the effect of epinephrine and norepinephrine on MDO2 and MVO2 using OCCM after five minutes of cardiopulmonary arres...

journal_title：Chest

authors： Lindner KH,Ahnefeld FW,Schuermann W,Bowdler IM

更新日期：1990-06-01 00:00:00

abstract：:We report a patient with situs inversus and ischemic heart disease who had myocardial revascularization with anastomosis of the right mammary artery to the anterior descending coronary artery. ...

journal_title：Chest

authors： Abensur H,Ramires JA,Dallan LA,Jatene A

更新日期：1988-10-01 00:00:00

abstract：:Results of preoperative pulmonary function tests were evaluated in 106 patients who had major thoracic or upper abdominal cardiovascular surgery. These results were related to the occurrence of postoperative complications by comparison of pulmonary function data in patients with an ICU stay of less than 5 days versus ...

journal_title：Chest

authors： Cain HD,Stevens PM,Adaniya R

更新日期：1979-08-01 00:00:00

abstract：:A 41-year-old woman had progressive shortness of breath. Cerebrotendinous xanthomatosis was diagnosed 4 years before. An open-lung biopsy showed the simultaneous presence of cerebrotendinous xanthomatosis and pulmonary lymphangioleiomyomatosis. This is perhaps the first time the coincidental occurrence of these two di...

journal_title：Chest

authors： Dormans TP,Verrips A,Bulten J,Cox N

更新日期：1997-07-01 00:00:00

abstract：:An unusual case of essential thrombocythemia in a young man presenting with progressive angina pectoris is presented. Angiography revealed proximal left anterior descending artery stenosis. Successful percutaneous transluminal angioplasty along with antiplatelet therapy and a calcium channel blocking drug have rendere...

journal_title：Chest

authors： Hanger KH Jr,Kilgore J,James E

更新日期：1984-12-01 00:00:00

abstract：:Eosinophilic pulmonary infiltration is an uncommon presentation from cocaine abuse. We present a patient with migratory pulmonary infiltrates and eosinophilia consistent with Löffler's syndrome. Our review uncovered two other similar patients. The importance of early recognition is stressed in our report. Either absti...

journal_title：Chest

authors： Nadeem S,Nasir N,Israel RH

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to determine the prevalence of Aspergillus fumigatus and Candida albicans in the sputa of patients with cystic fibrosis (CF), to assess serologic IgE responses of these patients to the presence of fungi in the sputum, to evaluate what effect this may have on clinical status,...

journal_title：Chest

authors： Máiz L,Cuevas M,Quirce S,Cañón JF,Pacheco A,Sousa A,Escobar H

更新日期：2002-03-01 00:00:00

abstract：:Herein is a report of an adult case of primary HIV infection with cytomegalovirus coinfection causing cough, fever, and lymphocytic alveolitis. Primary HIV infection has not been previously reported as a cause of lymphocytic alveolitis. ...

journal_title：Chest

authors： Jouveshomme S,Couderc LJ,Ferchal F,Vignon D,Autran B,Balloul E,Caubarrere I

更新日期：1997-10-01 00:00:00

abstract：:We describe two patients with histologically proven pulmonary Langerhans' cell histiocytosis in whom radiologic improvement occurred following smoking cessation. The patients had 23- and 25-pack-year smoking histories, respectively. High-resolution CT revealed multiple small nodules, located predominantly in the upper...

journal_title：Chest

authors： Mogulkoc N,Veral A,Bishop PW,Bayindir U,Pickering CA,Egan JJ

更新日期：1999-05-01 00:00:00

abstract：:The relative usefulness of a combination of some tumor markers, such as CEA, AFP, ferritin and NSE for the diagnosis of lung cancer was assessed by multiple logistic analysis. Serum concentration of these markers was determined in 68 patients with lung cancer (50 with NSCLC and 18 with SCLC, in 68 patients with benign...

journal_title：Chest

authors： Lombardi C,Tassi GF,Pizzocolo G,Donato F

更新日期：1990-03-01 00:00:00

abstract：:The antimicrobial resistance problem in hospitals continues to worsen. In particular, extended-spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-KP) and vancomycin-resistant enterococci (VRE) are significant causes of morbidity and mortality among critically ill patients. Treating infections caused by thes...

journal_title：Chest

authors： Patterson JE

更新日期：2001-02-01 00:00:00